KR20030079604A - The composition of improved materials in treating alcohol hangover and boosting an energy. - Google Patents

Abstract

PURPOSE: Provided is a composition for removing alcohol hangover and relieving fatigue which is prepared by extracting pharmacologically active ingredients of animals and plants and concentrating the extracts. CONSTITUTION: A composition for removing alcohol hangover and relieving fatigue contains 50-70 part by weight of an extract or essence oil from red ginseng, Lycium chinense Mill., Ganoderma lucidum, Hovenia dulcis Thunb., Citrus unshiu, Taraxacum Platycarpum H. dahlst., Gardenia Jasminoides, Pueraria thunbergiana, licorice root, and Cnidium officinale, 40-60 part by weight of an extract or essence oil from Cornus officinalis sied, et zucc, Eucommia ulmoides Hardy Rubber Tree, Cordyceps militaris, Allium tuberosum, Acanto Panax, Angelica uchiyamana, cervi parvum cornu, licorice root and the like, and 30-50 part by weigh of an extract or essence from Dioscorea japonica, Citrus nobilis, Asparagus cochinchinensis, Epimedii Folium, Bombyx mori Linne, Schizandra chinensis Baillon, Lonicera japonica, licorice root and Glycine max (L.) Merr.

Description

Hangover detoxification and fatigue recovery composition {The composition of improved materials in treating alcohol hangover and boosting an energy.}

The present invention relates to a pharmaceutically acceptable composition formulated and formulated through a three step process by adding dopamine to the medicinal components of medicinal animals and plants. In particular, the drug components of 1), 2) and 3) below are made to include DL-asparagine (DL-Asparagine) to synergize with each other.

1) In the first step, red ginseng is divided into 50 meshes of the medicinal plant. (Ginsenoside Ro, Ra-Rh, panaxynal, β- Elemen, β- sitosterol, Amino acid, peptides, Maltol, choline), Gugija (枸杞 子; main ingredient-Betaine, Vitamin B ₁ , Zeaxanthine, Physaline), Ganoderma lucidum (靈 芝; main ingredient-Gyrophoric acid, Lecanoric acid) 子; Main ingredient-Glucose, Calcium malate, Cheongpi (靑 皮-Main ingredient-d-Limonene, Hesperidin, Naringin, Aspartic acid), Pogongyoung (Main ingredient-Taraxacin, Taraxarol, Asparagin), Gardenia (梔子; Main ingredient-Geniposide, Genipin , Gardenoside, Crocin, Crocetin, Gardenin, Pectin), Brown root;川芎: It is a medicinal ingredient extracted by weighing and extracting the main ingredients-essential oils mainly including Ligustilide, Butylidenphthalide, Butylphthalide, Neocnidilide, Cnidilide, Sedanolide, and Senkyunolide.

2) In the second stage, medicinal animals and plants are treated with cornus (山茱萸; main components-Morroniside, Loganin, Cornin, Gallic acid, Malic acid), ; Main ingredient-Gutta-Percha, Kotose, Chlorogenic acid, Pectin), Cordyceps sinensis 夏 草; Main ingredients-Cordycepic acid, Cordycepin), Guja ( 子; Main ingredient-Allycysteine Sulfoxide, Vitamin C), Ogapi (五加皮; Main ingredient-Acanthoside A, B, C, D, Daucosterol, Polyacetylenes, Ziliodendlin, β- Sitosterol, Campesterol, Ethoxy-hydroxy-benzoid acid), Angelica (當歸; Main ingredient-Coumarin derivatives such as Decursin, Decursinol, Nodakenin, essential oils mainly composed of α -Pinene, Limonene, β -Eudesmol, Elemol, etc.), Deer Antler (鹿 茸), Protein, Phosphate, Calcium, Magnesium, Estrone ), Licorice (甘草; the main ingredients-Glycyrrhizin, Liquiritigenin, Glucose, Mannitol, Malic acid, ℓ-Asparagin) are each extracted by weight and take.

3) In the third step, as in 1), the medicine (山藥; main ingredient-Saponin, Mucin, Arginine, Allantoin, Amylase, Choline), dermis (秦 皮; main ingredient-Aesculetin, Aesculin), Astronomical (天 門冬; main ingredient-Asparasaponin IV, -V, -VI, -Ⅶ, Asparagine, β -sitosterol, 5-Methoxymethylfurfural), Yin and Yang Guk (淫羊藿; main components-Icariin, des-o-Methylicariin, Magnoflorine) 蠶; Main ingredient-Lipoprotein, Schizandrin, Gomisin A-Q, Citral, α- Ylangene, Citric acid, Malic acid, β- Chamigrene, Citric acid, Malic acid, β- Chamigrene, Fatty Oil金 銀花; main ingredients-Inositol, Luteolin, Tannin), licorice (甘草; main ingredients-Glycyrrhizin, Liquiritigenin, Glucose, Mannitol, Malic acid, ℓ-Asparagin), black bean (黑豆; main ingredients-Protein, Fatty Oil) Extracted medicine ingredient.

The composition of the present invention is a dopamine (Dopamine) and DL-asparagine so that more than 100 kinds of medicinal components of medicinal animals and plants through the process of steps 1, 2, 3 (DL-Asparagine) is added, extracted with ethyl alcohol (抽出) is a composition prepared by aging (maturation). The active ingredient of medicinal animals and plants is composed of water solubility and oil solubility. Conventionally, medicinal animals and plants are appropriately sliced, poured into a boiling water bath, boiled, and brought to a certain amount when squeezed into Mapocheong. Therefore, medicinal usefulness could not be taken. In the present invention, as in the constitution of the invention, medicinal animals and plants are sliced to obtain a <mesh recipe> to remove the toxicity in the active ingredient and to improve the composition of the drug>

Dopamine (dopamine = 3-Hydroxytyramine) and DL-Asparagine (DL-Asparagine = H ₂ NCOCH ₂ CH ( NH ₂ ) CO ₂ ㆍ H ㆍ H ₂ O ) are added to the mixture, and extracted with ethyl alcohol. Water-soluble and oil-soluble medicinal ingredients of medicinal animals and plants are almost extracted. In addition, since it is a powder or tablet (capsule) to more than 200 mesh powder, it is easy for human to take.

The drug effect is superior to that taken in the conventional medicine bath. In addition, it was found that the addition of dopamine (dopamine) significantly improves the cardiovascular system and the effects of blood circulation on the kidneys and liver when the drug is applied to the human body. Initial development goals of the present invention are as follows.

Diuretic effect (利 尿 作用), hepatocellular proliferation (肝 細胞 新生 促進 作用), blood clotting (淸 血 作用), cardiac action (强 心 作用), high blood pressure lowering (高血壓 降下), cholesterol lowering (cholesterol), diabetes (糖 尿), expansion of the coronary arteries (冠狀 張 作用), increased blood flow of the brain (腦 血流 作用), blood circulation improvement (血液 循環 改善 作用), stroke (中風), energy enhancement (精力, hepatoprotective, blue-heated fire, blue-heat detoxification, blood detoxification It is a drug that has been researched and developed for the purpose of 血 解毒, fatty liver, nourishing tonic effect, hangover detoxification, fatigue recovery, and improvement.

The drug component of the present invention contains about 100 kinds of drug components such as nourishing tonic action, antibacterial action, blue blood action, sexual function promotion action, hypoglycemic action, blood pressure lowering action. As such, it was a very difficult task to have more than 100 kinds of medicines act effectively on the human body. However, medicinal plants and plants were first formulated and completely solved by the addition of dopamine and DL-Asparagine. In addition, in order to process the medicinal ingredients more completely, 50 mesh powder was extracted before extraction, and the contact surface with ethyl alcohol was broadened and almost completely extracted. However, ethyl alcohol is a flammable substance and is very dangerous to fire. Accordingly used with 30-60% alcohol. Alcohols that evaporate during the concentration of medicinal extracts present a risk of pollution. This is done by recovering alcohol and supplementing the facility in mass production. In particular, the process of drying the concentrate was difficult. Above 120 ° C, the medicinal component was found to be reduced, and a special dryer was designed and completed. In addition, contaminants added during the handling of medicinal plants could be solved during the legal process. Contamination of bacteria during handling was also solved by drying to 120 ° C. The following concerns about the corruption of the drug. This is because no preservative is used in the present invention. However, because of the antimicrobial activity among the drug ingredients were able to solve by drying the concentrate 100%.

1) Red ginseng, Gugija, ganoderma lucidum, earthworm 50-70 parts by weight of each of Cheongpi, Cheongpi, Pogongyoung, Gardenia, Brown root, Cheongung, and 3% brine, 400-600 parts, Takju (ethyl alcohol 6%), namely 100-300 parts of makgeolli and 30-50 parts of milk was added to precipitate for 24 hours, and the salt, salt, and milk added were shaken well, washed and dried. After drying, 10-30 parts of black bean, 10-30 parts of licorice, and 700-900 parts of distilled water are taken and heated slowly for about 2 hours. When the beans are fully cooked, stop heating, cool, remove the black beans and licorice, and dry them. To this, 50-70 parts of licorice is added and pulverized to about 50 mesh. Then, 5-15 parts of dopamine, 10-30 parts of DL-Asparagine, and 700-900 parts of ethyl alcohol are added thereto. Seal the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble drug ingredients are extracted. This is filtered to obtain 600-800 parts. Concentrate the obtained solution again, and care should be taken as ethyl alcohol is flammable. Concentrate at 90-100 ° C. for 3 hours. This concentrated product was completely dried in a dryer at 100-120 ° C. for 5 hours. This product is made into powder which is 200 mesh or more.

2) Put medicinal animals and plants in container B as in 1) ), Cordyceps sinensis (冬) 夏 草), Guja ( Take 40-60 parts of oak, ogapi, Angelica and antler, weigh 300-500 parts of 3% brine, 100-300 parts of Takju (6% ethyl alcohol) and milk 30 Precipitate for 24 hours by adding -50 parts, shake the added brine, takju and milk well, and dry. After drying, 40-60 parts of licorice is added and pulverized to about 50 mesh. Then, 1-10 parts of dopamine, 10-20 parts of DL-Asparagine, and ethyl alcohol 500-700 Add and seal the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble drug ingredients are extracted. This was filtered to obtain 400-600 parts. This filtrate was concentrated to 90-100 ° C. for 3 hours. The concentrated product was dried in a dryer at 100-120 ° C. for 5 hours, and then ground to 200 mesh or more to obtain the product.

3) In the container C, as in 1), mountain medicine, Jinpi, Cheonmun-dong, Yin-Yang-Kwak, and Baekgang-Jam. -50) Take 30-50 parts of Omija and Geumhwa, respectively, and add 3% brine 200-400 parts, 100-200 parts of Takju and 30-50 parts of milk, and settle for 24 hours. Shake well, takju and milk, dry and dry. After drying, 30-50 parts of black bean and 30-50 parts of licorice are added and ground to 50 mesh, and then 1-10 parts of dopamine and 10-20 parts of DL-Asparagine, and Add 400-600 parts of ethyl alcohol and close the lid of the container. After 15 days, almost all of the water-soluble and oil-soluble components are extracted. This was filtered to obtain 300-500 parts. This filtrate was concentrated to 90-100 ° C. for 3 hours. The concentrated product was dried in a dryer at 100-120 ° C. for 5 hours, and then ground to 200 mesh or more to obtain the product. A, B, and C products are mixed and kneaded well to obtain the final product.

Example 1

1) Take red ginseng, gojija, ganoderma lucidum, earthworm, cheongpi, pogongyoung, gardenia, brown root, and cheongung each weighing 600g each in container A. 3% saline 5,000cc, Takju (ethyl alcohol 6 %) Add 2,000cc and 400cc of milk and settle for 24 hours, shake the added brine, Takju and milk well, dry them after drying. After drying, 200 g of black bean (black bean), 200 g of licorice and 8,000 cc of distilled water were taken and heated until the beans were fully ripe. It was heated for about 2 hours. When the beans are fully cooked, stop heating, cool, remove the black beans and licorice, and dry them. Add 600 g of licorice and grind it to about 50 mesh, add 99 g of dopamine, 198 g of DL-asparagine, and 8,000 cc of ethyl alcohol, and seal the lid of the container. Filtration was carried out after 15 days to obtain 7,000cc of a weak ingredient extract. This acquisition liquid was concentrated to 100 degreeC for 3 hours. This concentrated liquid was completely dried in a dryer for 5 hours. This was ground to 200 mesh or more to obtain 594 g of fine powder.

2) Take medicinal animals and plants in B container as in 1), and weigh 500g of cornus oil, tofu, cordyceps, guja, agapi, donkey, and deer antler, respectively, 3% brine 4,000cc, Takju (ethyl alcohol 6%) 2,000cc Add 400cc of milk and settle for 24 hours, shake the added brine, takju and milk well, wash and dry. After drying, 500g of licorice is added and pulverized to about 50 mesh and 73g of dopamine

Add 146 g of DL-Asparagine and 6,000 cc of ethyl alcohol and seal the lid of the container. Filtration after 15 days to obtain 5,000 cc of drug extract. This acquisition liquid was concentrated to 100 degreeC for 3 hours. This concentrated liquid was completely dried in a dryer for 5 hours. This was ground to 200 mesh or more to obtain 440 g of fine powder.

3) In the C container, take 400g each of powdered acid, dermis, astronomical dong, Yin Yang Kwak, Baekgangjam, Schisandra chinensis and Gold and Silver Coin as in 1), add 3% brine 3,000cc, 1,500cc Takju (6% ethyl alcohol) and 400cc milk. After settling for 24 hours, shake the added brine, takju and milk well, and dry them. After drying, 400g of black bean (black soybean) and 400g of licorice are pulverized to about 50 mesh, and then 66g of dopamine, 132g of DL-Asparagine and 5,000cc of ethyl alcohol are added to the lid of the container. Seal it. After 15 days, the solution was filtered to obtain 4,000 cc of drug substance extract. This acquisition liquid was concentrated to 100 degreeC for 3 hours. This concentrated liquid was completely dried in a dryer for 5 hours. This was ground to 200 mesh or more to obtain 396 g of fine powder. Acquisition of A, B, C containers The mixture was mixed and kneaded well, and finally 1,430 g of product was obtained. This was filled into capsules to produce 2,860 capsule medicines.

As described in the summary of the present invention as a medicinal effect of about 100 ingredients, Daebowongi (大補 元氣), Bokbok Ikbi (補肺 益脾), Bosin Ikjeong (補 賢 益 精), nomenclature (양 明目) , Bojung Ikgi (補中益氣), Yunheol Geodam, Cheongyeolsahwa (淸 熱 瀉火), Haeju poison, Cheongyeol detoxification (양 解毒), Blood detoxification ( 해 解毒, Haedoptojin, Activation of blood circulation, Bowik Ganshin, Kang Geun-gol, Antae, Food style seascape ), Hwadam mountain, fire breeze, wind breeze, blood landscape, blood circulation, active blood pain, bowie stomach, pulmonary dysfunction (,), Consonant (윤), yunjijihae (潤肺 止咳), Yang Yin Shengjin, Boxin Chaoyang (신 陽), autism Bosin (염) 익, Ixin fixation, blue liver nominal, nervous system excitement, adrenal cortex stimulation, sexual function promoting機能 促進 作用, cardiovascular action, hypoglycemic action, appetite boosting effect (食 항 作用), anti-anaphylaxis action, antidiuretic action (抗 利 尿 作用) , Nourishing tonic (滋養 强壯 作用), hepatocellular proliferation (肝 細胞 新生 促進 作用), detoxification (解毒 作用), corticoids (Corticoid, 作用), jingyeong (, 作用), stomach acid secretion inhibitory Action (거 分 거 制作 用), expectorant action (祛痰 作用), anti-inflammatory action (抗炎 作用), growth promoting action (發育 促進 作用), hematopoietic action (用 作用), dry stomach action (健胃 作用), sweating (發汗 作用), antifungal action (抗 眞 菌 作用), antipyretic action (解熱 作用), coronary artery dilatation action (作 動作 用 用), increase in blood flow to the brain (腦 血流增加 作用), Idam effect (利膽 作用), sedation (鎭 靜 作用), blood pressure lowering (血壓 降下 作用), nourishing (滋養 作用), vasodilation (血管 擴張 作用), analgesic action (鎭 痛 作用, anti-trichomonas action (抗 用 用), tonic action (强壯 作用), antiviral action (抗 Virus 作用), Jimangan (脂肪 肝), Jinhae effect (鎭 咳 作用), digestion promoting action (消化促進 作用, bronchial dilatation (氣管 支 擴張 作用), energetic strengthening (精力 통), transmutation (通便 作用), transsaminase lowering (Transaminase, 下 作用), relaxation (弛緩 作用), hangover detoxification ( It is a drug researched and developed with the goal of improving 및 解毒 and fatigue recovery.

If the present invention is commercialized as a health drink for improving hangover detoxification and fatigue recovery, the scope of application will be further expanded.

Self-clinical experiment example (for test "NANOPASS" taker)

1) The 60-year-old man was very weak and was too weak to climb or descend the stairs and felt tired easily. After taking this product for 1 month, he saw improvement in fatigue recovery and was able to live with confidence in everything. It can be said.

2) A 50-year-old middle-aged woman feels helpless and tired when everything is in the afternoon hours of the day, but after taking this product for a month, she can spend her day happily looking for the vitality of life.

3) A 45-year-old middle-aged man has excessive drinking for 5 days a week, and because of the hangover fatigue, it is very hard to take this product before drinking and after drinking. The fatigue could be solved.

4) After drinking both men and women, the hangover caused severe mash and severe headaches, and it was very hard. After taking this product, the hangover detoxification effect was improved.

5) The sample taker of the present invention has been more than 100 people wanted to sell as it is good, but because it is not a formal product was not available for sale, but with confidence in this drug, the name for filing an invention patent.

Claims (7)

After legislating medicinal animals and plants as in the invention A solution extracted with ethyl alcohol by adding 5-15 parts of dopamine and 10-30 parts of DL-Asparagine, 1) rosin senno side, Al-A-Al H., said panak day, β-elegans men, β-Saito sterol, amino acid, peptide, maltol, choline, betaine, vitamin B _1, if ssantin, Pisa Lin, gyro PO Lactic acid, Lecanoric acid, Glucose, Calcimal malat, d-limonene, hesperidin, naringin, aspartic acid, taracsulfate, tarasalol, asparagine, geniside, zenipine, gardnoside, crocin, crocetin , Gardnin, pectin, starch, dydzein, dydazine, fueraryin, glycyrrhizine, liquiritinigenin, mannitol, marimic acid, l-asparagine, ligustilide, butylidenephthalide, butylphthal 50-70 parts each of essential oils, such as essential oils such as Ryde, Neoknilide, Tsunidelide, Sedanolide and Sengranolide. 2) Moroniniside, Loganine, Colnin, Gallic Acid, Marimic Acid, Gutta-Percha, Cotose, Chlorogenic Acid, Pectin, Cordycepic Acid, Cordycepin, Alicysteine Sulfoside, Vitamin C, Acantoside Ko, such as A, B, C, D, Dowsterol, polyactetylene, ziliodendrin, β -cytosterol, campestrol, ethoxy-hydroxy-benzoic acid, decusin, decosinol, nodakenin, etc. Marine derivatives and α -pinene, limonene, β -eudesmol, elemol essential oil, colloid, protein, phosphate, calcidium, magnesium, estrone, glycyrrhizin, liquiditagenin, glucose, 40 to 60 parts each of mannitol and l-asparagine. 3) Saponin, mucin, arginine, allantoin, amylase, choline, escurin, escurin, asparasaponin VI, -V, -VI, -VIII, asparagine, β -cytosterol, 5-methoxymethylperfural, Icarin, Des-O-Methylacarin, Magnoflorin, Lipoprotein, Succidrin, Gomisin A-Q, Citral, α -Ilangen, Citric Acid, Maric Acid, β -Chammigren, Patioyl, AH A hangover detoxification and fatigue recovery composition prepared by concentrating, drying and crushing 30-50 parts of each of inositol, luteolin, tannin, glycyrrhizin, liquiditagenin, glucose, mannitol, l-asparagine, and protein. The various medicinal components in 1) of the main body and claim 1 are components extracted from plants of red ginseng, wolfberry, ganoderma lucidum, earth pear, green skin, pogongyoung, gardenia, brown root, licorice, and cheongung. The various medicinal components in the main body and 2) of claim 1 are components extracted from wild plants, plants, plants, cucumbers, cordyceps, angelica, antler, and licorice. Various drug components in the main body and 3) of claim 1 are extracted from plants of acid, dermis, astronomical dong, yin and yang, baekgangjam, schisandra, gold and silver, licorice, and black bean. The drugs used in the main body and the legislation in claim 1 are licorice, black bean (black bean), takju, milk (liquid) and 3% saline. Dopamine used in the text and claim 1 in the scientific name is a drug called dopamine (dopamine) or 3-hydroxytyramine hydrochloride (3-Hydroxytyramine Hydrochloride). As used in the text and in claim 1 it is Diel-asparagine (DL-Asparagine = H ₂ NCOCH ₂ CH ( NH ₂ ) CO ₂ ㆍ H ㆍ H ₂ O )