JP2009519055A - Antibacterial cellulose sheet - Google Patents

Abstract

  Include an antibacterial lotion in the cellulose sheet for paper towels. With this towel, the moisture absorption time (WAR) becomes longer, the lotion transfer to the skin is further promoted, and the transfer efficiency is improved.

Description

[Priority claim]
This formal application is based on US Provisional Application No. 60 / 748,499, filed Dec. 8, 2005 with the same invention name. Accordingly, the priority of US Provisional Application No. 60 / 748,499 is claimed here and the disclosure content is cited as a reference for this application.

  The present invention relates to a paper towel used as a hand towel. When this towel contains an antibacterial lotion, the moisture absorption time (WAR) becomes longer, the lotion transfer to the skin is further promoted, and the transfer efficiency is improved. The lotion is preferably applied as a microemulsion.

  Frequent hand washing is a simple and effective way to ensure proper hygiene and to prevent food contamination and disease transmission. Complex systems have been proposed that allow food providers and healthcare professionals to adequately perform frequent hand-washing because they are relatively more likely to cause undesirable contamination related to their activities. Yes.

  Cleaning the skin, especially the hands, with an antibacterial soap formulation can remove many viruses and bacteria from the cleaning surface. The removal of viruses and bacteria is due to the surface activity of the soap and the mechanical action during cleaning. Therefore, it is known and currently recommended that hand washing be performed frequently to reduce the transmission of viruses and bacteria. However, recent research has shown that although about 95% of people claim that they wash their hands after using public toilets, actual observations show that this figure does not exceed about 66%. . Although awareness of the need is increasing, there is a tendency to wash hands quickly, and as a result it cannot be denied that hygiene management is inadequate. Accordingly, many systems and devices have been developed that facilitate longer and more complete hand washing.

  Collopy in US Pat. No. 6,832,916 discloses a hand-washer with a display panel that encourages the user to perform hand-washing for about 15 seconds to remove bacteria. Gorra in US Pat. No. 5,945,910 discloses a method and apparatus for monitoring and reporting hand washing. This apparatus includes a sensor for causing the cleaning liquid to flow out of the dispenser and a module for reporting and monitoring. Allen in U.S. Pat. No. 5,781,942 discloses a cleaning station that monitors hand washing and assists in hand washing and its method of operation. These systems are relatively expensive, difficult to implement, and often require human training and monitoring. Even if such measures are taken, the probability that everyone will follow an appropriate cleaning procedure is small.

  Frequent hand washing has the disadvantage that soap and cleaning agents are irritating and can cause skin irritation and damage the acid mantle of the skin.

  Cellulose substrates coated with lotion are well known in the art. For example, US Pat. No. 5,665,426 to Krzysik et al. Relates to a lotion formulation that can be applied to tissue. With this tissue, the lotion moves to the user's skin, reducing the tingling and redness of the skin. US Pat. No. 5,871,763 to Luu et al. Also relates to a lotion formulation applied to a substrate used in skin care procedures. The lotion composition of the '763 patent is melted by the heat generated in the hands of the cellulose-based user, and the lotion can be transferred to the user's skin. Another lotion-treated substrate is described in US Pat. No. 5,525,345 to Warner et al. The lotion composition of the '345 patent consists of a plastic or flowable emollient that is solid or semi-solid at room temperature and an immobilizing agent that has a melting point above room temperature. This immobilizing agent stabilizes the lotion composition on the substrate surface. See also U.S. Patent Application No. 10 / 483,633 (U.S. Patent Application Publication No. 2005/0031847). This applies two distinct and different phases, lipid and water, to the substrate to facilitate skin cleansing. In addition, US Pat. No. 4,987,632 to Rowe et al. Describes a cleaning wipe treated with a composition comprising a detergent. This detergent is leached upon contact with water.

  A lotion containing an antibacterial agent and a pH balance agent for skin protection is also known. For example, US Pat. No. 6,238,682 to Klofta et al. Relates to a tissue treated with anhydrous skin lotion containing an antimicrobial component in addition to a hydrophilic solvent and a surfactant. See also U.S. Pat. No. 6,352,700 to Luu et al. This relates to a substrate treated with a lotion, which contains a compound that balances the pH of the skin and maintains an appropriate skin acid jacket. Regarding other lotions containing antibacterial agents, US Patent Application No. 10 / 608,661 (US Patent Application Publication No. 2004/0039353) on wet wipes containing Yucca seed extract as an antibacterial agent, US patent application Ser. No. 09 / 851,273 (U.S. Patent Application Publication No. 2002/0031486) relating to an antibacterial detergent composition that may contain little or no volatile alcohol, alone or in combination with lotions, US Pat. No. 6,436,885 to Biedermann et al. For an antimicrobial cleaning composition having a pH of about 2 to about 5.5, Kaiser for an antimicrobial lotion for topical use in the form of an oil-in-water emulsion. U.S. Pat. No. 6,383,505. Further, similar subjects include US Pat. No. 6,482,423 to Beerse et al., US Pat. No. 6,488,943 to Beers et al., US Pat. No. 6,284,259 to Beerse et al. US Pat. No. 6,258,368 to Beers et al., US Pat. No. 6,183,763 to Beers et al. And US Pat. No. 6,210,695 to Beers et al.

US Pat. No. 6,832,916 US Pat. No. 5,945,910 US Pat. No. 5,781,942 US Pat. No. 5,665,426 US Pat. No. 5,871,763 US Pat. No. 5,525,345 US Patent Application Publication No. 2005/0031847 U.S. Pat. No. 4,987,632 US Pat. No. 6,238,682 US Pat. No. 6,352,700 US Patent Application Publication No. 2004/0039353 US Patent Application Publication No. 2002/0031486 US Pat. No. 6,436,885 US Pat. No. 6,383,505 US Pat. No. 6,482,423 US Pat. No. 6,488,943 US Pat. No. 6,284,259 US Pat. No. 6,258,368 US Pat. No. 6,183,763 US Pat. No. 6,210,695

  Despite the abundance of technology, there is a need for a simple and effective way to promote hygiene and skin care simultaneously in connection with hand washing.

  A salient aspect of the present invention involves adding a suitable antimicrobial lotion to the substrate in an amount that actually lengthens the WAR of the cellulose sheet. This function is usually undesirable for towel products, but promotes the transfer of antimicrobial lotion to the skin. This is because the user wipes his / her hand with a towel for a longer period of time. Lotion transfer is crucial for both skin care and antibacterial efficacy, as will be appreciated by those skilled in the art.

  In one aspect of the present invention, an antimicrobial cellulose sheet comprising a) a cellulose web and b) a moveable lotion composition comprising a softener and an antimicrobial agent is provided for a paper towel. The lotion composition is immobilized on the cellulosic web in a solid or semi-solid form, and the movable lotion composition is movable from the lotion composition that is movable by contact with water or by the application of heat. A lotion composition. And c) the mobile lotion composition added to the web is selected and added in an amount that provides a water absorption rate delay of at least about 25% for the cellulosic web. In a preferred embodiment, the movable lotion composition added to the web is selected and added in an amount that provides a delayed water absorption rate of at least about 50%, 75%, 100% or more relative to the cellulose web. Is done. Therefore, it is also preferred that the non-lotion-added cellulose web has substantially the same SAT value as the lotion-added cellulose web. The cellulose sheet of the present invention may have a SAT value of at least about 3 g / g, at least about 3.5 g / g, at least about 4 g / g, or at least about 4.5 g / g. Generally, the cellulose sheet of the present invention has a SAT value of about 3 g / g to about 5 g / g.

  Lotioned cellulose sheets generally have a WAR value of at least about 40 seconds or 50 seconds. A WAR value of about 55 seconds to about 75 seconds is generally appropriate.

The movable lotion is preferably in an amount of about 3% to about 20% (based on the combined weight of the towel and lotion), for example in an amount of about 5% to about 15%, or about 8% Added to the cellulose web in an amount of ~ 10%. The non-lotion added cellulose web may have a basis weight of about 15 g / m < ² > to about 65 g / m < ² >, e.g., about 25 g / m < ² > to about 50 g / m < ² >. A basis weight of about 30 g / m < ² > to about 40 g / m < ² > is typical, and the cellulose web consists primarily of softwood fibers. The web may contain at least about 65-70% by weight of softwood fibers, typically about 70% to about 90% by weight of softwood fibers. The preferred softwood fibers are Douglas fir fibers, especially for electronic dispensers (motion sensitive). The sheet preferably has an eight sheet thickness of about 35 to about 90 mils (about 0.889 to about 2.286 millimeters), consists primarily of coniferous fibers, and is in the form of a single layer towel. is there.

  Generally, the lotion composition comprises from about 0.01% to about 10% by weight antimicrobial agent, preferably from about 0.05% to about 5% by weight antimicrobial agent. Antibacterial agents include 2,4,4′-trichloro-2′-hydroxydiphenyl ether, 3,4,4′-trichlorocarbanilide, 3,4,4′-trifluoromethyl-4,4′-dichlorocarbanilide. Lido, 5-chloro-2-methyl-4-isothiazolin-3-one, iodopropynyl butyl carbamate, 8-hydroxyquinoline, 8-hydroxyquinoline citrate, 8-hydroxyquinoline sulfate, 4-chloro-3,5-xylenol 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, butconazole, nystatin, terconazole, nitrofurantoin, phenazopyridine, acyclovir, chlortrimazole, chloroxylenol, chlorhexidine, chlorhexidine gluconate , Miconazole, ta Conazole, butylparaben, ethylparaben, methylparaben, methylchloroisothiazoline, methylisothiazoline, a mixture of 1,3-bis (hydroxymethyl) -5,5-dimethylhydantoin and 3-iodo-2-propynylbutylcarbamate, oxyquinoline, EDTA, EDTA tetrasodium, p-hydroxylbenzoate, alkylpyridinum compound, cocophoshatidyl PG-dimonium chloride, chlorhexidene digluconate, chlorhexidene acetate, chlorhexidene isothiocyanate, chlorhexidene hydrochloride , Benzalkonium chloride, benzethonium chloride, polyhexamethylene biguanide, zinc salts, and mixtures thereof.

  Web includes aldehyde-containing polyol, aldehyde-containing cationic starch, glyoxal, glutaraldehyde, dialdehyde, borate carbonate, zirconium ammonium carbonate, glyoxalated polyacrylamide, polyamide-epichlorohydrin, polyamine-epichlorohydrin, Optionally contains a wetting toughener selected from urea-formaldehyde, melamine-formaldehyde, polyethyleneimine, and latex emulsion.

One preferred embodiment is an antimicrobial cellulose sheet for seat towels, comprising a) a cellulose web and b) a lotion emulsion containing an antimicrobial agent added on the web. The lotion emulsion contains a polar softener and a nonpolar softener as well as a surfactant composition comprising a nonionic surfactant, and the lotion emulsion is substantially liquid at room temperature. The softener and surfactant composition are selected such that the lotion emulsion is fixed to the web in a semi-solid or solid form, and the lotion emulsion is capable of forming an aqueous gel when contacted with water. And c) the lotion composition added to the web is selected and added in an amount that provides a water absorption rate delay of at least about 25% relative to the cellulose web. In connection with this class of lotion application sheets, lotion emulsions generally comprise a polar softener in an amount of about 2% to about 40% based on the weight of the lotion emulsion, the lotion emulsion comprising propylene glycol, glycol, glycerol, A polar polyhydroxy softener selected from diethylene glycol, methylene glycol, polypropylene glycol, polyethylene glycol, and sorbitol may be included. The lotion emulsion also preferably includes a non-polar softener in an amount of about 10% to about 40% based on the weight of the lotion emulsion, the non-polar softener being an aromatic or chain ester, Guerbet ester. , Mineral oil, squalene, liquid paraffin, and mixtures thereof. Accordingly, suitable non-polar softeners include isopropyl myristate, C ₁₂ -C ₁₅ alkyl benzoate, tri-octyldodecyl citrate, a mixture of C ₁₂ -C ₁₅ alkyl benzoate esters, and carnation oil. Surfactant compositions may include nonionic surfactants containing fatty alcohol in an amount of about 40% to about 70% based on the weight of the lotion emulsion. Suitable nonionic surfactants are PEG-20 methyl glucose sesquistearate, PPG-20 methyl glucose ether, PPG-20 methyl glucose ether distearate, PEG-20 methyl glucose distearate, PEG-120 methyl glucose di-stearate. It may be selected from oleate, ethoxylated methyl glucose having about 10 to about 20 repeating ethoxy units, mixtures thereof, and the like. The surfactant composition most preferably comprises the co-surfactant in an amount of about 0.1% to about 20% based on the weight of the lotion emulsion. The co-surfactant is preferably a C ₁₂ -C ₁₈ fatty alcohol, behenyl alcohol, cetyl alcohol, stearyl alcohol, iso-cetyl alcohol and iso-stearyl alcohol, myristyl alcohol, and cetyl alcohol (C ₁₆ ) and stearyl alcohol. Selected from a mixture of (C ₁₈ ). In general, lotion emulsions are substantially anhydrous.

  Another preferred embodiment comprises: a) a cellulose web; and b) a substantially liquid anhydrous microemulsion at room temperature immobilized on the web in a semi-solid or solid state, wherein The anhydrous microemulsion comprises a surfactant composition comprising an antibacterial agent, a polar softener, a nonpolar softener, and a nonionic surfactant. Furthermore, the anhydrous microemulsion can form an aqueous microemulsion when contacted with water. And c) the anhydrous microemulsion added to the web is selected and added in an amount that results in a water absorption rate delay of at least about 25% relative to the cellulose web.

Yet another embodiment of the present invention is an antimicrobial cellulose sheet for paper towels, which is a) a cellulose web, and b) a movable lotion composition applied on the web, comprising a softener and an antimicrobial agent. And a retention / release agent, a ΔH greater than about 10 calories / gram above 37 ° C., a total heat greater than about 25 calories / gram at the melting point, and An antimicrobial cellulose sheet for paper towels comprising a moveable lotion composition having an onset of melting temperature of at least about 30 ° C., and c) a moveable lotion composition applied to a web comprising cellulose Selected and added in an amount that results in a water absorption rate delay of at least about 25% relative to the web. The lotion composition on the sheet optionally comprises a surfactant composition in an amount of about 10% to about 15% based on the weight of the lotion composition. The surfactant may be methyl glycoside sesquistearate, ethoxylated methyl glycoside sesquistearate containing 20 moles of oxyethylene units, a mixture of PEG-20 methyl glucose sesquistearate and methyl glucose sesquistearate, or a combination of the above compounds You can choose from. Preferably, the lotion composition comprises a softener in an amount of about 5% to about 75% based on the weight of the lotion composition. Softeners include aromatic ester softeners, ester softeners of non-fatty organic acids and fatty alcohols, or mixtures thereof. Typical aromatic ester softeners include C ₁₂ -C ₁₅ alkyl benzoate, stearyl benzoate, octyldodecyl benzoate, isostearyl benzoate, methyl glucoto-20 benzoate, stearyl ether benzoate, poloxamer 182 dibenzoate, poloxamer 105 dibenzoate, or Mention may be made of these mixtures. Softeners for esters of non-fatty organic acids and fatty alcohols include C ₁₂ -C ₁₅ octanoates.

The heat sensitive lotion composition generally comprises a retention / release agent in an amount of about 25% to about 95% based on the weight of the lotion composition. Holding / releasing agent may be a C ₁₂ -C ₁₈ fatty alcohols. Suitable fatty alcohols are selected from dodecanol, tridecanol, tetradecanol, pentadecanol, hexadecanol, heptadecanol, octadecanol, a mixture of cetyl alcohol and stearyl alcohol and combinations of said compounds.

  Further aspects of the invention will become clear from the discussion below.

The present invention is described in detail below by way of example only. Modifications within the spirit and scope of the present invention as set forth in the claims will be readily apparent to those skilled in the art. As used herein, terms and abbreviations have their usual meanings. For example, “cp” means centipoise, g means gram, mg means milligram, m ² means square meter, and so on.

  The absorbency of the product of the present invention is measured with a simple absorbency tester. This simple absorbency tester is a particularly useful device for measuring the hydrophilic and absorption properties of tissue, napkins or towel samples. In this test, a 2.0 inch (5.08 centimeter) diameter tissue, napkin, or towel sample is placed between the top flat plastic cover and the bottom grooved sample plate. A tissue, napkin, or towel disc sample is securely held by a 1/8 inch (3.175 mm) annular flange section. Do not compress the sample with the holder. 73 ° F. (about 22.8 ° C.) deionized water is introduced into the sample placed on the bottom sample plate via a 1 mm caliber conduit. This water is at a hydrostatic pressure of minus 5 mm water column. The flow is started with a pulse made by the instrument mechanism at the start of the measurement. Thus, water is absorbed into the tissue, napkin, or towel sample in a radially outward direction from the central entry point by capillary action. The test ends when the water absorption rate decreases to 0.005 g or less per 5 seconds. Weigh the amount of water removed from the storage tank and absorbed by the sample and report the results as grams of water per square meter of sample or grams of water per gram of sheet. In practice, the M / K Systems Inc. Gravimetric Absorbency Testing System is used. This is a commercial system commercially available from M / K Systems (Massachusetts, Danvers, Garden Street 12). WAC, or water absorption capacity, also called SAT, is actually measured by the instrument itself. WAC is defined as the point at which the slope of the water absorption vs. time graph is “zero”, that is, the point at which the sample stops absorbing water. The termination criterion for the test is expressed as the maximum change in the weight of water absorbed over a period of time. This basically shows the point where the slope is zero on the weight versus time graph. In the program, the end point is the time when only 0.005 g has changed in 5 seconds. However, when “slow SAT” is defined, the cutoff criterion is 1 mg for 20 seconds.

  The water absorption rate, or WAR, is the time taken to absorb 0.1 g of water droplets measured in seconds and loaded on the sample surface with an automatic injector. The test specimen is preferably conditioned to 23 ° C. ± 1 ° C. (73.4 ° F. ± 1.8 ° F.) at 50% relative humidity. For each sample, four 3 × 3 inch (7.62 × 7.62 cm) test specimens are made. Each specimen is placed in a sample holder, and a high-intensity lamp is irradiated on the specimen. Place 0.1 mL of water on the specimen surface and start the stopwatch. At the end of water absorption, this is indicated by the absence of further light reflection from the water droplets, but the stopwatch is stopped and the time is recorded in 0.1 second increments. This procedure is repeated for each specimen and the results are averaged for each sample. WAR is measured according to TAPPI method T-432 om-99.

  The water absorption rate delay in percent is calculated as follows from the WAR values of the cellulose web without lotion and the lotion-added sheet product of the present invention. That is,

[Equation 1]
Absorption rate delay =
(WAR value of cellulose sheet added with lotion−WAR value of cellulose web without addition of lotion) ÷ (WAR value of cellulose web without addition of lotion) × 100%

  “Aqueous gel” refers to a viscous lotion / water composition having a room temperature viscosity of generally about 500 cp (mPa · s) or more at room temperature, generally about 1,000 cp or more at room temperature. Preferred lotion compositions form gels of greater than 1,500 cp at room temperature as seen in Table 2 below.

  “Basis weight”, BWT, bwt, etc. are indicated in grams per square meter of product, or pounds per 3,000 square feet.

  Terms such as “cellulose” and “cellulose sheet” are meant to include any product containing papermaking fibers based on cellulose. “Papermaking fibers” includes virgin pulp or recycled (secondary) cellulose fibers or fiber mix comprising cellulose fibers. Suitable fibers for producing the webs of the present invention include fibers obtained from deciduous and coniferous trees, for example, coniferous fibers such as northern and southern softwood kraft fibers and hardwood fibers such as eucalyptus, maple, hippopotamus, poplar, etc. In addition, it contains non-wood based cellulose fibers. Papermaking fibers are separated from raw materials using any one of a wide variety of chemical pulping processes well known to those skilled in the art, including pulping processes such as sulfate, sulfite, polysulfide, and soda processes. Can do. The pulp can be bleached by chemical methods, including the use of chlorine, chlorine dioxide, oxygen, alkaline peroxide, etc., if desired. The product of the present invention is a blend of conventional fibers (whether virgin pulp and those derived from recycled raw materials) and tube-like fibers rich in coarse lignin, such as bleached chemical thermomechanical pulp (BCTMP). It can be included. Terms such as “furnish” refer to an aqueous composition that includes fibers for making paper products and, optionally, wet strength resins and disintegrants.

  The fibers of the towel product of the present invention are preferably composed mainly of softwood (SW) fibers such as bay pine (over 50% by weight on a fiber content basis). Southern softwood craft (SSWK) is also a preferred fiber. Softwood fibers give strength to the product. Southern softwood is generally preferred for the towels of the present invention. However, thin, soft northern softwood can also be used in the fiber mixture.

  Unless otherwise specified, “%” means “% by weight”, and unless otherwise specified, it means “% by weight without water”. Terms or expressions such as the weight percent of softwood fibers refer to the weight percent of softwood fibers based on the fiber content of the product or composition, excluding other ingredients.

  Room temperature refers to a temperature of about 20 ° C to 25 ° C.

  For dry tensile strength (MD and CD directions), elongation, ratio of these, modulus, cut modulus, stress and strain, standard Instron tester, or other suitable stretch tensions that can be configured variously Use a strip of tissue or towel, typically 3 inches (7.62 cm) or 1 inch (2.54 cm) wide, on a tester, 23 ° ± 1 ° C. (73.4 ° ± 1 ° F. at 50% relative humidity) ) And tempering for 2 hours in the atmosphere. The tensile test is performed at a crosshead speed of 2 inches / minute (5.08 cm / minute). The cutting modulus is expressed in grams / 3 inches /% strain. Strain% is dimensionless and does not require any regulation.

  The tensile strength ratio is simply the ratio of the values measured by the method described above. The tensile properties are those of the dry sheet unless otherwise specified.

  The wet tensile strength of the tissue of the present invention is a 3 inch (7.62 cm) wide strip of tissue formed in a loop and fixed to a special instrument called a Finch Cup, Measured by immersion in water. The Finch Cup is available from Thwing-Albert Instrument Company, Philadelphia, Pennsylvania, and attaches to a 2.0 pound load cell equipped tensile tester. The fin of the finch cup is fastened to the lower jaw of the testing machine, and the end of the tissue loop is fastened to the upper jaw of the tensile testing machine. The sample is immersed in water adjusted to a pH of 7.0 ± 0.1, and the tensile test is performed after 5 seconds of immersion.

  Terms such as “anhydrous”, “substantially anhydrous” generally refer to compositions comprising less than about 10% water by weight. In the case where water is present in the first place, it is preferable that water is not added as water but is contained in other components as water.

  In some preferred embodiments of the present invention, the lotion composition is described in US patent application Ser. No. 10 / 141,442 filed May 7, 2002 (US Patent Application Publication No. 2003/0211124). "Cold" lotion. This application is incorporated herein by reference. “Cold” lotion refers to a lotion that is substantially liquid at room temperature and can be applied as a liquid to a substrate. Because “cold” lotions are in a liquid state at room temperature, they do not require equipment for heating or melting, and substrates with several adoptable techniques such as spraying, printing, coating, extrusion, or other techniques Can be added.

  The cold lotion used in the present invention contains a microemulsion composition mainly comprising a softener composition and a surfactant composition. The particle size of the microemulsion is so small that the surface area of the component is increased and the usefulness of the composition of the present invention by improving the interaction between the softener and the skin surface, i.e. desirable properties for the repair of the skin oil layer. Contributes to sex. Preferably, the microemulsion composition contains a mixture of an external continuous nonpolar or polar softener, an internal discontinuous polar or nonpolar softener, a surfactant, and a fatty alcohol-based cosurfactant. Lotion compositions may contain optionally applicable ingredients, such as typical cosmetic additives, preservatives, botanical extracts, fragrances, and pharmaceutical agents. Any combination and any ratio of the ingredients that form the microemulsion can be used.

  An important aspect of the cold lotion used is that when the liquid lotion contacts the fiber or nonwoven substrate, it causes a phase change in situ from the liquid to the immobilized semi-solid or solid form. This phase change of the lotion results when the substrate web surface fibers absorb the continuous external phase of the microemulsion. In this case, the microemulsion can be a nonpolar or polar softener. Thereafter, the% of the microemulsion external phase in the composition decreases, the% of the microemulsion internal phase increases, and the composition of the original lotion changes from point A (liquid microemulsion) to point B or C (semi-solid). Shift to state). Point B or C is located outside the microemulsion region (see FIG. 1). The immobilized antibacterial lotion can be restored to a mobile form upon contact with water, forming an aqueous gel. The composition of the present invention is preferably selected to be within the microemulsion region of a given formulation. All percentages, ratios, and ratios of the components present in the compositions of the present invention are polar softener / nonpolar softener / cosurfactant / nonionic surfactant formulation (PE / NPE / COS / NIS). In the three-phase phase diagram of the microemulsion region. Outside the microemulsion region on the low% side of polar or non-polar softeners, it is preferred that there be a semi-solid or solid region. Microemulsions are thermodynamically stable and are essentially transparent in the visible region of the spectrum. This generally indicates that the particle size is preferably less than about 0.1 μm. When the particle size is greater than about 3,200 angstroms (about 0.32 micrometers), the liquid is no longer considered a microemulsion and the liquid often appears cloudy and is a thermodynamically unstable emulsion. It is. The micelle structure of the microemulsion is either “direct” type (head outside / tail inside) or “inverse” type (head inside / tail outside). Liquid microemulsions increase the surface area of the lipophilic component and contribute significantly to the usefulness of the compositions of the present invention in a clean form. The fluidity, small particle size, high surface area, and high hydrophilic properties on the skin surface achieve the cleaning purpose when the substrate itself is used or when the lotioned product is rewet with water This is a very desirable property. These components that form the microemulsion can be used in any combination and in any ratio.

  The hot lotion composition used in connection with the present invention has a ΔH of about 37 ° C. or more of about 10 calories / gram or more, a ΔH of about 37 ° C. or less of about 15 calories / gram or more, The total ΔH (total energy to melting) above about 37 ° C. is selected to be about 25 calories / gram. Further, the retention / release agent is preferably selected to have a melting point substantially higher than about room temperature but lower than about 65 ° C., and the lotion onset of melting temperature is about 30 ° C. To be in the range of ~ 45 ° C. This allows the lotion composition to be substantially in a solid state at approximately room temperature and partially maintain a molten state at human skin temperature.

  It should be noted that for purposes of this description, the human skin temperature is about 30 ° C. to about 37 ° C., and the room temperature is about 20 ° C. to about 25 ° C.

  An important aspect of the hot lotion used is that it is partially melted by body heat, partially liquefied, partially solid state softener (s) and retention / release agent particles and other ingredients It is possible to move to the skin. Partial melting of the lotion is important. This is because if the lotion is completely melted into a liquid by body heat, it will feel too oily, and if the lotion is not sufficiently melted by body heat, it will not easily diffuse onto the skin. At least a portion of the partially melted lotion resolidifies on the skin, forming a smooth and moisturizing layer. Further details regarding suitable hot lotion compositions are found in US Pat. No. 5,871,763, the entire disclosure of which is hereby incorporated by reference.

  Antibacterial lotions optionally include coronavirus, picornavirus, renovirus, herpes simplex, genital herpes, cold sores, respiratory zinc virus (RSV), parainfluenza, cytomegalovirus, adenovirus Effective against certain synergistic disease states that can be associated with viruses, protozoa, or viruses and unfriendly enzymes such as proteases, lipases, and amylases that give rise to susceptible skin as a pioneering condition, dystrophy, and viral infections Or a suitable antiviral agent comprising at least an inhibitory antiviral agent. Specific antiviral agents suitable for use in lotions include bioflavonoids, such as certain selected amino acids from legumes such as hesperitin, naringin, catechin and L-canavanine and L-arginine. And dicarboxylic acids such as malonic acid, glutaric acid, citric acid, succinic acid, and diglycolic acid, α-hydroxycarboquinic acid such as D-galacturonic acid obtained from Karaya tree, and unmodified In the form of neem seed oil (Azadiracta indica) and unmodified form of sandalwood (sandalwood) oil (Santalum album L.). Optionally, the antiviral agent can be formulated with up to about 50% by weight of a protease inhibitor antiviral agent such as zinc oxide or other suitable zinc salt.

  Cold or hot lotion compositions may optionally contain other ingredients that are generally present in this type of lotion. These optionally applicable ingredients include aloe extract, avocado oil, basil extract, sesame oil, olive oil, jojoba oil and chamomile extract, eucalyptus extract, plant extract such as peppermint extract, and also emu oil, Contains animal oils such as cod liver oil, orange luffy fish oil and mink oil.

  The lotion of the present invention may also optionally include a wetting agent. A humectant is a hygroscopic material having a dual moisture imparting action including water retention and water absorption. Humectants prevent moisture loss from the skin and attract moisture from the environment. Preferred wetting agents include glycerol, hydrolyzed silk, ammonium lactate, hydroxypropyltrimonium hydrolyzed silk, hydroxypropyl chitosan, hydroxypropyltrimonium hydrolyzed wheat protein, lactamidepropyltrimonium chloride, and ethyl ester of hydrolyzed silk Is mentioned. The plant extract, animal oil, or wetting agent is preferably present in an amount of less than about 3% when used in a lotion base formulation. Further, in some cases, optional components include skin refreshing agents such as capsule-in-oil water, eucalyptus oil, and menthol oil. All these optional materials are well known in the art as additives for such formulations and can be employed in the appropriate amounts for the lotion compositions of the present invention by those skilled in the art.

  The lotion may optionally contain a fragrance. The perfume may be present in an amount from 0.01% to about 2%. Suitable fragrances include volatile aromatic esters, non-aromatic esters, aromatic aldehydes, non-aromatic aldehydes, aromatic alcohols, non-aromatic alcohols, heterocyclic aromatic drugs, and roses, carnations, gardenia, geraniums. , Natural flower-derived fragrances such as iris, hawthorn, hyacinth and jasmine.

  The lotion may also optionally contain natural or synthetic powders such as talc, mica, boron nitride, silicone, or mixtures thereof.

  The towel web of the present invention may be any suitable cellulosic substrate web, optionally with the addition of a wet strength agent, and optionally a synthetic fiber such as melt spun polyethylene, polypropylene, polyethylene. Polymers can be included. The substrate can also be embossed.

  The wet strength agents that can be added include temporary wet strength agents as well as temporary wet strength agents. Suitable wet strength agents include non-active selected from the group consisting of glyoxal, glutaraldehyde, dialdehyde, aldehyde-containing polyol, non-active aldehyde-containing polymer, cyclic urea, mixtures thereof and aldehyde-containing cationic starch Type chemical subgroups, mixtures of polyvinyl alcohol and salts of polyvalent anions such as boric acid or ammonium zirconium carbonate, glyoxalated polyacrylamide, polyamide-epichlorohydrin, polyamide-epichlorohydrin, urea-formaldehyde, melamine-formaldehyde, polyethyleneimine and Examples include latex emulsions.

  The present invention includes a cellulosic fibrous web that is treated on at least one side with an antimicrobial lotion. The amount is preferably from about 0.1% to about 25%, more preferably from about 0.5% to about 20%, based on the weight of the dry fiber web.

  Cellulose substrates can be made according to conventional processes known to those skilled in the art (TAD, CWP and variations thereof). A preferred towel web is a shrink-woven towel web as used in Example 18. The lotion can be applied to the substrate according to conventional application methods known to those skilled in the art.

[Examples 1-7]
When an anhydrous lotion formulation is prepared, the ingredients, ratios, and conditions selected to provide a microemulsion that undergoes an in situ phase change upon contact with a cellulose substrate are shown in the examples below. Changed to be.

  In preparing each formulation, the following general procedure was used. The polar phase propylene glycol was mixed with the surfactant and co-surfactant in a heated vessel at about 60 ° C. to about 70 ° C. to completely melt the drug. A non-polar oil phase was added to the mixture and stirred moderately for about 10 minutes and then cooled to room temperature. In this regard, the lotion was in the form of a clear liquid and could be easily added to the substrate. The microemulsion formed spontaneously without the need for a high shear machine and was infinitely stable.

  Examples 1-7 were prepared according to US patent application Ser. No. 10 / 141,442. This disclosure is incorporated herein by reference. These lotion formulations are liquid at room temperature, transparent and extremely stable, so the lotion component ratio is a micro of phase phase diagram such as FIG. 1, which is a partial phase phase diagram of the composition of Example 1. It was in the emulsion area. Surprisingly, the lotion of the present invention has the characteristics that the touch is excellent and the hand does not feel oily. This is presumably because the oil phase cannot be detected with the fingertip because the particle size of the microemulsion is extremely small.

[Example 8]
The lotion prepared in Example 1 was added to the tissue substrate sheet at a 5% addition level and then converted to a bilayer tissue product. This product was tested and the amount of lotion transferred to the skin was determined. The results were compared to commercially available lotion-loaded tissue. In comparison, the cold lotion remaining on the glass was reflected on the other two products. The scattering of light caused by the lotion remaining on the glass slide of the microscope was measured using a UV / visible spectrophotometer in the wavelength region of 700 nm to 400 nm. The lotion was moved by holding the glass slide between two lotion-added tissues for 30 seconds and then rubbing the tissue 20 times on the slide for 15 seconds. The lotion remaining on the glass slide was placed under the sample beam of a UV / visible light double beam spectrophotometer, and light scattering was measured. The results indicate that the light scattering caused by the lotion remaining on the slide rubbed with the tissue treated with the lotion of Example 1 is the same as the control (untreated tissue). Looked like. However, the two commercially available lotion-added facial tissue products subjected to the test produced a significant amount of light scattering when compared to the lotion-added tissue of the present invention. In fact, the containers for these products are specially stated as “not recommended to wipe glasses cleanly”. Furthermore, laboratory tests have determined that the amount of lotion transferred to the skin with the lotion loaded substrate of the present invention is about 4.2 mg / cm ² .

  The lotion-added substrate product of the present invention was able to “transfer the glasses and maintain a clear field of view” while allowing the lotion to move to the skin to enhance skin care benefits. These properties of the present invention represent a significant advantage over prior art lotioned facial tissue.

  The anhydrous emulsion composition of the present invention has a myriad of attributes that make it particularly suitable for paper towels. For one thing, anhydrous microemulsions form low-viscosity aqueous microemulsions with relatively small amounts of water, so that a lotion immobilized on a substrate recovers when wetted with water or mixed with water. And can be moved easily. Thus, for example, upon contact with the wet hand of a paper towel user, the lotion is easily transferred from the towel to the user's skin.

  Another unique property of the present invention is that as the amount of water mixed with the lotion increases, the lotion emulsion can combine with the water to form a highly viscous gel. Gels are generally more desirable as hand lotions because they are generally more colloidal than liquids.

  Details regarding these properties are provided in Examples 9-16 below.

[Examples 9 to 16]
The composition of Example 1 was mixed with water and tested for viscosity using a Brookfield digital viscometer at 73 ° F. (about 22.8 ° C.). Examples 9, 10, 11 and 16 are no. Tests were performed with 2 spindles, while Examples 12, 13, 14 and 15 were No. The test was performed with 5 spindles. Details regarding the composition and test conditions are given in Table 2 below.

  It can be seen in Table 2 that the water / emulsion mixture remained in the microemulsion state to a water concentration of 10% to 15% by weight of the composition (Examples 9-12). At a water concentration of 15%, the lotion emulsion turned into a viscous gel and became more viscous as more water was added. When the water concentration was 20%, the composition became an elastic gel having a viscosity of 22,000 cp (mPa · s), and viscosity measurement became difficult. At a water concentration of 30% (Example 14), the gel was somewhat opaque, some crystal structure appeared and appeared to be almost brittle. For Example 13, the practical difference in viscosity between Examples 13 and 14 is less than shown in Table 2 due to the difficulty of measuring viscosity in addition to the elastic and adhesive properties of the elastic gel. Can be considered.

  At a water concentration of 50% by weight, the viscosity dropped dramatically and the composition became a thick, turbid gel, showing some translucency. The viscosities of Examples 12 and 15 were equivalent, and the composition of Example 14 showed a fairly high turbidity. At a water concentration of 80%, the viscosity decreased again, but the composition was no longer clear and showed the appearance of a somewhat turbid emulsion.

  The phase behavior of the mixtures in Table 2 is shown in the partial phase diagram of FIG. It can be seen that Examples 9, 10 and 11 are in the microemulsion region of the phase diagram. Examples 12, 13, 14 and 15 are in a “semi-solid” state, while Example 16 is a two-phase liquid.

[Example 17 and Comparative Example A]
Yet another feature of the present invention that is highly desirable is the WAR delay function that promotes lotion transfer to the skin and the antibacterial action of the paper towel. These functions are understood from the following discussion.

  A towel base sheet was filed on June 12, 2006 (Attorney Docket No. 20079; GP-05-10), co-pending US patent application Ser. No. 11 / 451,111, entitled “Shrink Weave Sheet for Dispenser ( Fabric-Creped Sheet for Dispensers), using a class of shrink woven / yankee dry method, using 100% Bay Pine craft fiber. The entire disclosure content of that application is incorporated herein by reference. Using this base sheet with the Dynatec ™ applicator of the class found in US Pat. Nos. 5,904,298, 5,902,540, and 5,882,573 Lotions were applied in 1 inch (2.54 cm) wide bands along the machine direction (alternatively to 1 inch (2.54 cm) wide bands without addition of lotion). The entire disclosure is cited herein as a reference. The lotion formulation of Example 1 was used, but additionally contained 2% by weight of the lotion triclosan antimicrobial compound, 2,4,4'-trichloro-2'-hydroxydiphenyl ether. Further details are shown in Table 3 below.

  The towels were treated to obtain antibacterial properties by placing a circular specimen of a wet towel in agar medium inoculated with a fungus in a Petri dish. The antibacterial properties are “negative” if microbial contamination is observed on or around the towel itself after culturing the bacteria, and “positive” if a “ring” is observed around the test specimen. The latter indicates that microbial growth was inhibited with a towel.

  The results of the antibacterial test are also shown in Table 3.

  As can be seen in Table 3, the antibacterial lotion was effective against S. aureus, E. coli, and Salmonella.

  It can also be seen that the absorption capacity (SAT) of the control and the lotion-added towel is substantially the same, but the WAR time, i.e. the absorption rate, has increased considerably, which is probably due to the gel blocking action ( gel blockage) and is consistent with the data in Table 2 above. WAR is generally not desirable, but the gel feel and initial “wetness” experienced by towel users is a positive result, offsetting and wiping low absorption rate measurements Therefore, the antimicrobial lotion of the present invention is more effective in preventing or improving soiling. The apparent gel blocking action also appears to increase the wet tensile strength in the CD direction. The common cause of towel destruction is its low value.

[Examples 18 to 22]
The lotion compositions of the following examples are composed of a basic lotion with and without a pH balance agent. Suitable pH balance agents include glycolic acid, α-acetylglycolic acid, lactic acid, tartaric acid, α-acetyllactic acid, α-hydroxyisobutyric acid, salicylic acid, mandelic acid, o-acetylmandelic acid, benzylic acid, o-acetyl. Benzyl acid, malic acid, citric acid, gluconic acid, pyruvic acid, sorbic acid, and mixtures thereof. Examples 18 and 19 are for comparison and do not contain any pH balance agents, and Examples 20-22 relate to lotion compositions mixed with pH balance agents. Further details can be found in US Pat. No. 6,352,700. The entire disclosure is cited herein as a reference.

  The lotions of Examples 20-22 were prepared according to the following procedure. The basic lotion ingredients, i.e., softener (s), release / retainer and surfactant were mixed together and heated to 75 ° C to completely melt the mixture. See the ingredients of the lotion composition in Table 4. The lotion composition mixture was maintained at 75 ° C. with moderate agitation for about 15 minutes. The pH balancer compound was then added, stirring was increased and the compound was completely melted and mixed. The pH value of each lotion is emulsified with 0.276 g of a solid lotion (corresponding to the amount of lotion contained in 5 sheets of 15% lotion added tissue) in 23 mL of 20 mL of tap water (pH = 8.65). Was measured. The emulsion was shaken for 5 minutes, after which the pH was measured using a standard calibrated pH meter.

  While the invention has been described in terms of many embodiments, it will be readily apparent to those skilled in the art that modifications may be made to these embodiments within the spirit and scope of the invention. In light of the foregoing discussion, appropriate knowledge of the art, and references including the above-mentioned co-pending applications, all relevant disclosures are included herein by reference and no further explanation is necessary. It is said.

2 is a partial phase diagram of the composition of Example 1 showing the phase characteristics of the anhydrous microemulsion. FIG. 2 is a partial phase diagram of water and the composition of Example 1 illustrating the phase behavior of the mixture of the composition of Example 1 and water. FIG.

Claims (69)

An antimicrobial cellulose sheet for paper towels,
a) a cellulose web;
b) A movable lotion composition comprising a softener and an antibacterial agent, wherein the lotion composition is immobilized on the cellulose web in a solid or semi-solid form;
Including
The movable lotion composition is selected from a lotion composition that is movable when contacted with water, or a lotion composition that is movable when heat is applied;
c) The antimicrobial cellulose sheet, wherein the movable lotion composition added to the web is selected and added in an amount that causes a delay in water absorption rate of at least about 25% to the cellulose web.   2. The antimicrobial cellulose sheet according to claim 1, wherein the movable lotion composition added to the web is selected and added in an amount that causes a delayed water absorption rate to the cellulose web of at least about 50%. Antibacterial cellulose sheet.   2. The antimicrobial cellulose sheet of claim 1 wherein the movable lotion composition added to the web is selected and added in an amount that provides a delayed water absorption rate to the cellulose web of at least about 70%. Antibacterial cellulose sheet.   2. The antimicrobial cellulose sheet of claim 1 wherein the movable lotion composition added to the web is selected and added in an amount that provides a delayed water absorption rate to the cellulose web of at least about 100%. Antibacterial cellulose sheet.   2. The antibacterial cellulose sheet according to claim 1, wherein the lotion-free cellulose web has the same SAT value as the lotion-added cellulose web.   The antimicrobial cellulose sheet of claim 1, wherein the cellulose sheet has a SAT value of at least about 3 g / g.   The antimicrobial cellulose sheet according to claim 1, wherein the cellulose sheet has a SAT value of at least about 3.5 g / g.   The antimicrobial cellulose sheet of claim 1, wherein the cellulose sheet has a SAT value of at least about 4 g / g.   The antimicrobial cellulose sheet of claim 1, wherein the cellulose sheet has a SAT value of at least about 4.5 g / g.   The antimicrobial cellulose sheet according to claim 1, wherein the cellulose sheet has a SAT value of about 3 g / g to about 5 g / g.   The antimicrobial cellulose sheet of claim 1, wherein the cellulose sheet has a WAR value of at least about 40 seconds.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose sheet has a WAR value of at least about 50 seconds.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose sheet has a WAR value of about 55 seconds to about 75 seconds.   The antimicrobial cellulose sheet of claim 1, wherein the movable lotion is added to the cellulose web in an amount of about 3 wt% to about 20 wt%.   The antimicrobial cellulose sheet of claim 1, wherein the movable lotion is added to the cellulose web in an amount of about 5 wt% to about 15 wt%.   The antimicrobial cellulose sheet of claim 1, wherein the movable lotion is added to the cellulose web in an amount of about 8 wt% to about 10 wt%. In anti-microbial cellulosic sheet according to Claim 1, antimicrobial cellulosic sheet which is the cellulosic web lotion not added, and having from about 15 g / m ² basis weight of about 65 g / m ^2. 2. The antimicrobial cellulose sheet according to claim 1, wherein the lotion-free cellulose web has a basis weight of about 25 g / m < ² > to about 50 g / m < ² >. 2. The antimicrobial cellulose sheet according to claim 1, wherein the non-lotion-added cellulose web has a basis weight of about 30 g / m < ² > to about 40 g / m < ² >.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose web is mainly composed of softwood fibers.   2. The antimicrobial cellulose sheet of claim 1, wherein the cellulose web comprises at least about 65% by weight of softwood fibers.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose web comprises at least about 70% by weight of softwood fibers.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose web contains about 70% to about 90% by weight of softwood fibers.   2. The antimicrobial cellulose sheet according to claim 1, wherein the cellulose web is mainly composed of bay pine fibers.   2. The antimicrobial cellulose sheet of claim 1, wherein the sheet has an 8 sheet thickness of about 35 mils to about 90 mils, consists primarily of coniferous fibers and is in the form of a single layer towel. Sheet.   2. The antimicrobial cellulose sheet of claim 1, wherein the cellulose web comprises at least about 70% by weight bay pine fibers.   The antibacterial cellulose sheet according to claim 1, wherein the lotion composition comprises about 0.01 wt% to about 10 wt% of an antibacterial agent.   2. The antimicrobial cellulose sheet according to claim 1, wherein the lotion composition comprises about 0.05% to about 5% by weight of an antimicrobial agent.   2,4,4′-trichloro-2′-hydroxydiphenyl ether, 3,4,4′-trichlorocarbanilide, 3,4,4′-trifluoromethyl-4,4′-dichlorocarbanilide, 5- Chloro-2-methyl-4-isothiazolin-3-one, iodopropynylbutylcarbamate, 8-hydroxyquinoline, 8-hydroxyquinoline citrate, 8-hydroxyquinoline sulfate, 4-chloro-3,5-xylenol, 2-bromo 2-nitropropane-1,3-diol, diazolidinyl urea, butconazole, nystatin, terconazole, nitrofurantoin, phenazopiphenazopyridine, acyclovir, chlortrimazole, chloroxylenol, chlorhexidine, chlorhexidine gluconate, Miconazole, ta Conazole, butylparaben, ethylparaben, methylparaben, methylchloroisothiazoline, methylisothiazoline, mixture of 1,3-bis (hydroxymethyl) -5,5-dimethylhydantoin and 3-iodo-2-propynylbutylcarbamate, oxyquinoline, EDTA EDTA tetrasodium, p-hydroxylbenzoate, alkylpyridinum compound, cocophoshatidyl PG-dimonium chloride, chlorhexidene digluconate, chlorhexidene acetate, chlorhexidene isothiocyanate, chlorhexidene hydrochloride, The antibacterial of claim 1, comprising an antibacterial agent selected from benzalkonium chloride, benzethonium chloride, polyhexamethylene biguanide, and mixtures thereof. Cellulose sheet.   The antibacterial cellulose sheet according to claim 1, wherein the antibacterial agent is 2,4,4'-trichloro-2'-hydroxydiphenyl ether.   The antibacterial cellulose sheet according to claim 1, wherein the antibacterial agent contains benzalkonium chloride.   2. The antibacterial cellulose sheet according to claim 1, wherein the antibacterial agent contains a zinc salt.   The antibacterial cellulose sheet according to claim 1, wherein the cellulose web is mainly softwood fibers, and the antibacterial agent is 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichloro. Carbanilide, 3,4,4′-trifluoromethyl-4,4′-dichlorocarbanilide, 5-chloro-2-methyl-4-isothiazolin-3-one, iodopropynylbutylcarbamate, 8-hydroxyquinoline , 8-hydroxyquinoline citrate, 8-hydroxyquinoline sulfate, 4-chloro-3,5-xylenol, 2-bromo-2-nitropropane-1,3-diol, diazolidinyl urea, butconazole, nystatin, turconazole , Nitrofurantoin, phenazopiphenazopyridine, acyclo , Chlortrimazole, chloroxylenol, chlorhexidine, chlorhexidine gluconate, miconazole, terconazole, butylparaben, ethylparaben, methylparaben, methylchloroisothiazoline, methylisothiazoline, 1,3-bis (hydroxymethyl) -5,5-dimethyl Mixture of hydantoin and 3-iodo-2-propynylbutylcarbamate, oxyquinoline, EDTA, tetrasodium EDTA, p-hydroxylbenzoate, alkylpyridinum compound, cocophoshatidyl PG-dimonium chloride, chlorhexidene digluconate, Chlorhexidene acetate, Chlorhexidene isothiocyanate, Chlorhexidene hydrochloride, Benzalkonium chloride, Benzethonium chloride, Poly Antimicrobial cellulosic sheet, wherein hexamethylene biguanide, and that the mixtures thereof.   2. The antimicrobial cellulose sheet according to claim 1, wherein the web contains a wet strength agent.   The antibacterial cellulose sheet according to claim 34, wherein the wet strength agent is an aldehyde-containing polyol, an aldehyde-containing cationic starch, glyoxal, glutaraldehyde, dialdehyde, borate carbonate, zirconium ammonium carbonate, glyoxalized polyacrylamide, An antimicrobial cellulose sheet characterized in that it is selected from polyamide-epichlorohydrin, polyamine-epichlorohydrin, urea-formaldehyde, melamine-formaldehyde polyethyleneimine, and latex emulsion. An antimicrobial cellulose sheet for paper towels,
a) a cellulose web;
b) a lotion emulsion containing an antibacterial agent added to a web, wherein the lotion emulsion comprises a polar softener, a nonpolar softener and a surfactant composition further comprising a nonionic surfactant; The emulsion is substantially liquid at room temperature, the surfactant composition is selected to be fixed to the web in a solid or semi-solid form, and the lotion emulsion is aqueous when contacted with water. A lotion emulsion that can form a gel;
Including
c) The antibacterial cellulose sheet, wherein the lotion emulsion added to the web is selected and added in an amount that causes a delay in water absorption rate of at least about 25% to the cellulose web.   37. The antimicrobial cellulose sheet according to claim 36, wherein the lotion emulsion comprises a polar softener in an amount of about 2% to about 40% based on the weight of the lotion emulsion.   37. The antimicrobial cellulose sheet according to claim 36, wherein the lotion emulsion comprises a polar polyhydroxy softener selected from propylene glycol, glycol, glycerol, diethylene glycol, methylene glycol, polypropylene glycol, polyethylene glycol, and sorbitol. Antibacterial cellulose sheet.   The antimicrobial cellulose sheet according to claim 38, wherein the polar softener is propylene glycol.   37. The antimicrobial cellulose sheet of claim 36, wherein the lotion emulsion comprises a nonpolar softener in an amount of about 10% to about 40% based on the weight of the lotion emulsion.   37. The antimicrobial cellulose sheet of claim 36, wherein the lotion emulsion comprises a non-polar softener selected from aromatic or chain esters, gerbe esters, mineral oil, squalene, liquid paraffin, and mixtures thereof. An antibacterial cellulose sheet.   42. The antibacterial cellulose sheet according to claim 41, wherein the nonpolar softener is isopropyl myristate. In the antimicrobial cellulosic sheet of claim 41, wherein the non-polar emollient is antimicrobial cellulosic sheet which is a C ₁₂ -C ₁₅ alkyl benzoate.   42. The antibacterial cellulose sheet according to claim 41, wherein the nonpolar softening agent is tri-octyldodecyl citrate. In the antimicrobial cellulosic sheet of claim 41, wherein the non-polar emollient is antimicrobial cellulosic sheet which is a mixture of C ₁₂ -C ₁₅ alkyl benzoate and carnation oil.   37. The antimicrobial cellulose sheet of claim 36, wherein the surfactant composition comprises a nonpolar softener containing a fatty alcohol in an amount of about 40% to about 70% based on the weight of the lotion emulsion. Antibacterial cellulose sheet.   37. The antimicrobial cellulose sheet according to claim 36, wherein the surfactant composition comprises PEG-20 methyl glucose sesquistearate, PPG-20 methyl glucose ether, PPG-20 methyl glucose ether distearate, PEG-20 methyl glucose. Nonionic surfactants selected from distearate, PEG-120 methylglucose dioleate, ethoxylated methylglucose having about 10 to about 20 repeating ethoxy units, and mixtures thereof Antibacterial cellulose sheet.   48. The antibacterial cellulose sheet according to claim 47, wherein the nonionic surfactant contains PEG-20 methyl glucose sesquistearate.   48. The antibacterial cellulose sheet according to claim 47, wherein the nonionic surfactant contains PEG-20 methylglucose distearate.   37. The antimicrobial cellulose sheet of claim 36, wherein the surfactant composition comprises a co-surfactant in an amount of about 0.1% to about 20% based on the weight of the lotion emulsion. Sheet. In the antimicrobial cellulosic sheet of claim 50, wherein the surfactant composition, C ₁₂ -C ₁₈ fatty alcohols, behenyl alcohol, cetyl alcohol, stearyl alcohol, iso - co chosen from stearyl alcohol - cetyl alcohol, and iso An antimicrobial cellulose sheet comprising a surfactant.   51. The antimicrobial cellulose sheet according to claim 50, wherein the cosurfactant is myristyl alcohol. In the antimicrobial cellulosic sheet of claim 50, wherein the co-surfactant, antibacterial cellulosic sheet which is a mixture of cetyl alcohol (C ₁₆₎ and stearyl alcohol (C _18).   37. The antibacterial cellulose sheet according to claim 36, wherein the lotion emulsion is substantially anhydrous. An antimicrobial cellulose sheet,
a) a cellulose web;
b) an anhydrous microemulsion that is substantially liquid at room temperature and immobilized on the web in a semi-solid or solid form;
Including
c) The anhydrous microemulsion comprises an antibacterial agent, a polar softener, a nonpolar softener, and a surfactant composition containing a nonionic surfactant, and when the anhydrous microemulsion comes into contact with water, an aqueous microemulsion Can be formed,
d) An antibacterial cellulose sheet, wherein the anhydrous lotion emulsion added to the web is selected and added in an amount that causes a delay in water absorption rate of at least 25% to the cellulose web. An antimicrobial cellulose sheet,
a) a cellulose web;
b) A moveable lotion composition applied to a web, the moveable lotion composition comprising a softener, an antibacterial agent, and a retention / release agent, wherein the lotion is about 10 calories above about 37 ° C. A lotion composition having a ΔH greater than / gram, a total heat of greater than or equal to about 25 calories / gram at the melting point, and a melting onset temperature of at least about 30 ° C .;
Including
c) The antimicrobial cellulose sheet, wherein the movable lotion composition added to the web is selected and added in an amount that causes a water absorption rate delay of at least about 25% relative to the cellulose web.   57. The antimicrobial cellulose sheet of claim 56, wherein the lotion composition further comprises a surfactant composition in an amount of about 10% to about 15% based on the weight of the lotion composition. Sheet.   57. The antibacterial cellulose sheet according to claim 56, wherein the lotion composition is further selected from methyl glycoside sesquistearate, ethoxylated methyl glycoside sesquistearate containing 20 moles of oxyethylene units, or a mixture thereof. An antimicrobial cellulose sheet comprising an active agent.   57. The antimicrobial cellulose sheet according to claim 56, wherein the surfactant comprises a mixture of PEG-20 methyl glucose sesquistearate and methyl glucose sesquistearate.   57. The antimicrobial cellulose sheet of claim 56, wherein the lotion composition comprises a softener in an amount of about 5% to about 75% based on the weight of the lotion composition.   61. The antibacterial cellulose sheet according to claim 60, wherein the softener includes an aromatic ester softener, a softener of an ester of a non-aliphatic organic acid and a fatty alcohol, or a mixture thereof. Sheet. In the antimicrobial cellulosic sheet of claim 61, wherein the aromatic ester softener, C ₁₂ -C ₁₅ alkyl benzoate, stearyl benzoate, octyldodecyl benzoate, isostearyl benzoate, Mechiruguruseto -20 benzoate, stearyl ether benzoate, poloxamer 182 di An antimicrobial cellulose sheet characterized in that it is a benzoate softener selected from benzoate, poloxamer 105 dibenzoate, or a mixture thereof. In the antimicrobial cellulosic sheet of claim 61, wherein the softening agent of the non-fat organic acids and esters of fatty alcohols, antimicrobial cellulosic sheet which comprises a C ₁₂ -C ₁₅ octanoate. In anti-microbial cellulosic sheet according to Claim 61, antibacterial cellulose sheets the softening agent, characterized in that it is a mixture of C ₁₂ -C ₁₅ alkyl benzoate.   57. The antimicrobial cellulose sheet of claim 56, wherein the lotion composition comprises a retention / release agent in an amount of about 25% to about 95% based on the weight of the lotion composition. In the antimicrobial cellulosic sheet of claim 56, wherein the retention / release agent, antibacterial cellulosic sheet which comprises a C ₁₂ -C ₁₈ fatty alcohols.   67. The antimicrobial cellulose sheet of claim 66, wherein the fatty alcohol is selected from dodecanol, tridecanol, tetradecanol, pentadecanol, hexadecanol, heptadecanol, octadecanol, or mixtures thereof. An antibacterial cellulose sheet.   70. The antibacterial cellulose sheet according to claim 66, wherein the fatty alcohol is a mixture of cetyl alcohol and stearyl alcohol.   57. The antimicrobial cellulose sheet according to claim 56, wherein the lotion composition is substantially anhydrous.

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