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IT8320066A0 - 6'ALKYL ANALOGUES OF SPECTINOMICIN AND METHODS FOR THEIR PREPARATION. - Google Patents

6'ALKYL ANALOGUES OF SPECTINOMICIN AND METHODS FOR THEIR PREPARATION.

Info

Publication number
IT8320066A0
IT8320066A0 IT8320066A IT2006683A IT8320066A0 IT 8320066 A0 IT8320066 A0 IT 8320066A0 IT 8320066 A IT8320066 A IT 8320066A IT 2006683 A IT2006683 A IT 2006683A IT 8320066 A0 IT8320066 A0 IT 8320066A0
Authority
IT
Italy
Prior art keywords
spectinomicin
preparation
methods
alkyl analogues
analogues
Prior art date
Application number
IT8320066A
Other languages
Italian (it)
Other versions
IT1164157B (en
Inventor
David Raymond White
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IT8320066A0 publication Critical patent/IT8320066A0/en
Application granted granted Critical
Publication of IT1164157B publication Critical patent/IT1164157B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT20066/83A 1982-03-19 1983-03-14 6'ALCHIL ANALOGS OF SPECTINOMYCIN METHODS FOR THEIR PREPARATION IT1164157B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35972382A 1982-03-19 1982-03-19
US06/449,304 US4532336A (en) 1982-03-19 1982-12-13 6'-Alkylspectinomycins

Publications (2)

Publication Number Publication Date
IT8320066A0 true IT8320066A0 (en) 1983-03-14
IT1164157B IT1164157B (en) 1987-04-08

Family

ID=27000602

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20066/83A IT1164157B (en) 1982-03-19 1983-03-14 6'ALCHIL ANALOGS OF SPECTINOMYCIN METHODS FOR THEIR PREPARATION

Country Status (10)

Country Link
US (1) US4532336A (en)
JP (1) JPH0776222B2 (en)
BE (1) BE896215A (en)
DE (1) DE3308196A1 (en)
FR (1) FR2523583B1 (en)
GB (1) GB2117757B (en)
HK (1) HK61788A (en)
IT (1) IT1164157B (en)
MX (1) MX9203211A (en)
NL (1) NL8300893A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532336A (en) * 1982-03-19 1985-07-30 The Upjohn Company 6'-Alkylspectinomycins
US4578485A (en) * 1984-02-08 1986-03-25 The Upjohn Company Synthesis of spectinomycin analogs by an improved Grignard process
US4895870A (en) * 1985-03-29 1990-01-23 The Upjohn Company Treating chlamydia infections using spectinomycin analogs
US4730059A (en) * 1986-03-10 1988-03-08 The Upjohn Company 6'-thiomethylsubstituted spectinomycins
WO1991004256A1 (en) * 1989-09-13 1991-04-04 The Upjohn Company Gamma alkylation of a protected derivative of the enone of spectinomycin
US5048126A (en) * 1989-10-02 1991-09-17 Mclaughlin James G Protective apparel
CN104725392B (en) * 2013-12-24 2017-01-11 中国农业大学 Half antigen SPE-EDE and corresponding artificial antigen and application therefore

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3234092A (en) * 1959-10-20 1966-02-08 Upjohn Co Actinospectacin and process for producing same
DE2756914A1 (en) * 1977-12-21 1979-07-05 Thomae Gmbh Dr K 4-SPECTINOMYCYLAMINE AND ITS PHYSIOLOGICALLY COMPATIBLE SALTS, METHOD FOR THE PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
GB2050348B (en) * 1979-03-13 1983-08-03 Upjohn Co Spectinomycin analogues
US4351771A (en) * 1979-03-13 1982-09-28 The Upjohn Company Spectinomycin analogs and methods for the preparation thereof
US4282152A (en) * 1979-08-23 1981-08-04 The Upjohn Company Intermediates for preparing spectinomycin and analogs thereof
BE887456R (en) * 1981-02-10 1981-08-10 Upjohn Co PROCESS FOR PRODUCING INTERMEDIATE COMPOUNDS FOR OBTAINING SPECTINOMYCIN AND THE LIKE THEREOF AND PRODUCTS THEREOF
US4420623A (en) * 1981-07-20 1983-12-13 The Upjohn Company Process and intermediates for preparing 6'-methylspectinomycin and analogs thereof
US4380651A (en) * 1981-07-20 1983-04-19 The Upjohn Company Process for preparing 6'-methylspectinomycin and analogs thereof
US4405797A (en) * 1981-10-16 1983-09-20 The Upjohn Company Process for preparing spectinomycin analogs: N-demethylation of spectinomycin or its analogs and realkylation of the intermediates
US4465848A (en) * 1981-10-23 1984-08-14 The Upjohn Company Spectinomycin compounds
US4532336A (en) * 1982-03-19 1985-07-30 The Upjohn Company 6'-Alkylspectinomycins

Also Published As

Publication number Publication date
IT1164157B (en) 1987-04-08
GB2117757B (en) 1985-08-29
FR2523583A1 (en) 1983-09-23
JPH0776222B2 (en) 1995-08-16
GB2117757A (en) 1983-10-19
FR2523583B1 (en) 1987-06-12
GB8304026D0 (en) 1983-03-16
DE3308196C2 (en) 1993-06-09
NL8300893A (en) 1983-10-17
HK61788A (en) 1988-08-19
DE3308196A1 (en) 1983-09-29
JPH0649072A (en) 1994-02-22
MX9203211A (en) 1992-09-01
US4532336A (en) 1985-07-30
BE896215A (en) 1983-09-19

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960329