IT1230140B - Derivati della serina, loro processo di preparazione e impiego in terapia umana - Google Patents
Derivati della serina, loro processo di preparazione e impiego in terapia umanaInfo
- Publication number
- IT1230140B IT1230140B IT8920357A IT2035789A IT1230140B IT 1230140 B IT1230140 B IT 1230140B IT 8920357 A IT8920357 A IT 8920357A IT 2035789 A IT2035789 A IT 2035789A IT 1230140 B IT1230140 B IT 1230140B
- Authority
- IT
- Italy
- Prior art keywords
- derivatives
- serina
- preparation
- human therapy
- therapy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N serine Chemical class OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- -1 araliphatic Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 150000003354 serine derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8920357A IT1230140B (it) | 1989-05-03 | 1989-05-03 | Derivati della serina, loro processo di preparazione e impiego in terapia umana |
EP90108222A EP0396080B1 (en) | 1989-05-03 | 1990-04-30 | New serine derivatives, process for their preparation and their use in human therapy |
ES90108222T ES2070202T3 (es) | 1989-05-03 | 1990-04-30 | Nuevos derivados de serina, procedimiento para su preparacion y su uso en terapia humana. |
DE69016085T DE69016085T2 (de) | 1989-05-03 | 1990-04-30 | Serinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung in der Humantherapie. |
AT90108222T ATE117307T1 (de) | 1989-05-03 | 1990-04-30 | Serinderivate, verfahren zu ihrer herstellung und ihre verwendung in der humantherapie. |
JP2118501A JPH0735389B2 (ja) | 1989-05-03 | 1990-05-07 | 新規セリン誘導体、その製造方法およびヒト治療への用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8920357A IT1230140B (it) | 1989-05-03 | 1989-05-03 | Derivati della serina, loro processo di preparazione e impiego in terapia umana |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8920357A0 IT8920357A0 (it) | 1989-05-03 |
IT1230140B true IT1230140B (it) | 1991-10-14 |
Family
ID=11166005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8920357A IT1230140B (it) | 1989-05-03 | 1989-05-03 | Derivati della serina, loro processo di preparazione e impiego in terapia umana |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0396080B1 (it) |
JP (1) | JPH0735389B2 (it) |
AT (1) | ATE117307T1 (it) |
DE (1) | DE69016085T2 (it) |
ES (1) | ES2070202T3 (it) |
IT (1) | IT1230140B (it) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1249063B (it) * | 1991-05-28 | 1995-02-11 | Fidia Spa | Impiego di derivati fosfolipidici per la preparazione di composizioni farmaceutiche aventi attivita' immunosoppressiva |
JP3053537B2 (ja) * | 1994-11-08 | 2000-06-19 | 株式会社ヤクルト本社 | 脳機能改善剤 |
US6242473B1 (en) * | 1999-01-08 | 2001-06-05 | Maxim Pharmaceuticals, Inc. | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
JP5140824B2 (ja) * | 2006-04-19 | 2013-02-13 | 国立大学法人 東京大学 | リゾホスファチジルスレオニンおよびその誘導体 |
JP2010184867A (ja) * | 2009-02-10 | 2010-08-26 | Univ Of Tokyo | リゾホスファチジルスレオニン誘導体 |
JP6153019B2 (ja) * | 2013-01-31 | 2017-06-28 | 国立大学法人 東京大学 | リゾホスファチジルセリン受容体機能調節活性を有する化合物 |
CN118184697B (zh) * | 2024-03-18 | 2024-10-22 | 中国人民解放军联勤保障部队第九〇四医院 | 一种具有膦酸酯结构的氨基酸衍生物及其在制备抗缺氧药物中的用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1123142B (it) * | 1979-09-14 | 1986-04-30 | Lpb Ist Farm | Uso di glicerilfosforil derivati nella terapia di dislipemie ed epatiti,e composizioni farmaceutiche relative |
ATE45744T1 (de) * | 1984-07-25 | 1989-09-15 | Ciba Geigy Ag | Phosphatidylverbindungen, verfahren zu ihrer herstellung und ihre verwendung. |
IT1213034B (it) * | 1986-02-12 | 1989-12-07 | Istituto Chemioterapico Di Lod | Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale. |
-
1989
- 1989-05-03 IT IT8920357A patent/IT1230140B/it active
-
1990
- 1990-04-30 ES ES90108222T patent/ES2070202T3/es not_active Expired - Lifetime
- 1990-04-30 EP EP90108222A patent/EP0396080B1/en not_active Expired - Lifetime
- 1990-04-30 AT AT90108222T patent/ATE117307T1/de not_active IP Right Cessation
- 1990-04-30 DE DE69016085T patent/DE69016085T2/de not_active Expired - Fee Related
- 1990-05-07 JP JP2118501A patent/JPH0735389B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH02306982A (ja) | 1990-12-20 |
ATE117307T1 (de) | 1995-02-15 |
EP0396080A2 (en) | 1990-11-07 |
JPH0735389B2 (ja) | 1995-04-19 |
DE69016085T2 (de) | 1995-05-18 |
IT8920357A0 (it) | 1989-05-03 |
DE69016085D1 (de) | 1995-03-02 |
EP0396080A3 (en) | 1991-04-10 |
EP0396080B1 (en) | 1995-01-18 |
ES2070202T3 (es) | 1995-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950525 |