HU9601685D0 - 4,5-diaryloxazole derivatives - Google Patents
4,5-diaryloxazole derivativesInfo
- Publication number
- HU9601685D0 HU9601685D0 HU9601685A HU9601685A HU9601685D0 HU 9601685 D0 HU9601685 D0 HU 9601685D0 HU 9601685 A HU9601685 A HU 9601685A HU 9601685 A HU9601685 A HU 9601685A HU 9601685 D0 HU9601685 D0 HU 9601685D0
- Authority
- HU
- Hungary
- Prior art keywords
- aryl
- lower alkylene
- diaryloxazole
- derivatives
- suitable substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939325962A GB9325962D0 (en) | 1993-12-20 | 1993-12-20 | Heterocyclic compounds |
GB9422404A GB9422404D0 (en) | 1994-11-07 | 1994-11-07 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9601685D0 true HU9601685D0 (en) | 1996-08-28 |
HUT76341A HUT76341A (en) | 1997-08-28 |
Family
ID=26304051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9601685A HUT76341A (en) | 1993-12-20 | 1994-12-16 | Process for preparation of 4,5-diaryloxazole derivatives and pharmaceutical compositions containing them |
Country Status (17)
Country | Link |
---|---|
US (1) | US6025375A (hu) |
EP (1) | EP0736018B1 (hu) |
JP (1) | JPH09506894A (hu) |
KR (1) | KR100345943B1 (hu) |
CN (2) | CN1046714C (hu) |
AT (1) | ATE194335T1 (hu) |
AU (1) | AU686286B2 (hu) |
CA (1) | CA2179399A1 (hu) |
DE (1) | DE69425162T2 (hu) |
DK (1) | DK0736018T3 (hu) |
ES (1) | ES2147836T3 (hu) |
GR (1) | GR3034542T3 (hu) |
HU (1) | HUT76341A (hu) |
PT (1) | PT736018E (hu) |
RU (1) | RU2176640C2 (hu) |
TW (1) | TW374086B (hu) |
WO (1) | WO1995017393A1 (hu) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW401408B (en) * | 1995-07-21 | 2000-08-11 | Fujisawa Pharmaceutical Co | Heterocyclic compounds having prostaglandin I2 agonism |
AUPO713297A0 (en) * | 1997-06-02 | 1997-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compound |
GB9720270D0 (en) | 1997-09-25 | 1997-11-26 | Pharmagene Lab Limited | Medicaments for the treatment of migraine |
AUPP003297A0 (en) * | 1997-10-27 | 1997-11-20 | Fujisawa Pharmaceutical Co., Ltd. | 4,5-diaryloxazole compounds |
AUPP029197A0 (en) | 1997-11-10 | 1997-12-04 | Fujisawa Pharmaceutical Co., Ltd. | Benzocycloheptene derivatives |
AUPP109097A0 (en) | 1997-12-22 | 1998-01-22 | Fujisawa Pharmaceutical Co., Ltd. | Napthalene derivatives |
BR9913833A (pt) | 1998-09-17 | 2001-05-29 | Bristol Myers Squibb Co | Método para tratar diabetes, empregando em inibidor de ap2 e combinação |
US7358254B2 (en) | 2001-07-13 | 2008-04-15 | Bristol-Myers Squibb Company | Method for treating atherosclerosis employing an aP2 inhibitor and combination |
AUPP608898A0 (en) * | 1998-09-23 | 1998-10-15 | Fujisawa Pharmaceutical Co., Ltd. | New use of prostaglandin E2 antagonists |
US6437146B1 (en) | 1998-09-25 | 2002-08-20 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compounds as prostaglandin e2 agonists or antagonists |
AU2005201289B2 (en) * | 1999-02-12 | 2008-04-17 | President And Fellows Of Harvard College | Inhibiting formation of atherosclerotic lesions |
IL145122A0 (en) | 1999-03-05 | 2002-06-30 | Procter & Gamble | C16 unsaturated fp-selective prostaglandin analogs |
KR20020015345A (ko) * | 1999-06-21 | 2002-02-27 | 후지야마 아키라 | 피부 궤양 치료제 |
US6894175B1 (en) * | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
AUPQ253199A0 (en) * | 1999-08-30 | 1999-09-23 | Fujisawa Pharmaceutical Co., Ltd. | Non-prostanoid prostaglandin I2-agonist |
US7390824B1 (en) | 1999-09-07 | 2008-06-24 | Bristol-Myers Squibb Company | Method for treating diabetes employing an aP2 inhibitor and combination |
DE60038902D1 (de) * | 2000-03-24 | 2008-06-26 | Asterand Uk Ltd | Verwendung von prostanoid-ep4-rezeptor-antagonisten zur behandlung von kopfschmerzen und nachweisverfahren für solche antagonisten |
US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
US20020172693A1 (en) * | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
US20020037914A1 (en) * | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
US20020146439A1 (en) * | 2000-03-31 | 2002-10-10 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins |
US20040116530A1 (en) * | 2001-04-18 | 2004-06-17 | Noriaki Maeda | Tissue fibrosis inhibitors |
AU2003216920A1 (en) | 2002-04-08 | 2003-10-20 | Glaxo Group Limited | (2-((2-alkoxy)-phenyl)-cyclopent-1-enyl) aromatic carbo and heterocyclic acid and derivatives |
GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
TW200505446A (en) * | 2003-01-17 | 2005-02-16 | Fuj Isawa Pharmaceutical Co Ltd | Inhibitor of cox |
US7439372B2 (en) * | 2006-05-03 | 2008-10-21 | Allergan, Inc. | Therapeutic compounds |
US20090016981A1 (en) | 2006-05-03 | 2009-01-15 | Allergan, Inc. | Therapeutic compounds |
US8217027B2 (en) * | 2006-12-21 | 2012-07-10 | Abbott Laboratories | Sphingosine-1-phosphate receptor agonist and antagonist compounds |
CA2676252A1 (en) | 2007-01-25 | 2008-07-31 | Allergan, Inc. | Substituted arylcyclopentenes as therapeutic agents |
US9365485B2 (en) | 2007-01-25 | 2016-06-14 | Allergan, Inc. | Substituted arylcyclopentenes as therapeutic agents |
US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
US8623918B2 (en) * | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
TWI435874B (zh) | 2008-10-31 | 2014-05-01 | Toray Industries | 環己烷衍生物及其醫藥用途 |
WO2010122169A1 (en) * | 2009-04-24 | 2010-10-28 | Basf Se | 5-mercapto- [1,2, 4] triazole compounds and their agricultural and pharmaceutical uses |
US8969573B2 (en) * | 2010-06-28 | 2015-03-03 | President And Fellows Of Harvard College | Compounds for the inhibition of cellular proliferation |
WO2014194209A1 (en) | 2013-05-31 | 2014-12-04 | Allergan, Inc. | Substituted cyclopentenes as therapeutic agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3578671A (en) * | 1967-11-06 | 1971-05-11 | Wyeth John & Brother Ltd | Oxazoles |
US4072689A (en) * | 1973-02-22 | 1978-02-07 | Gruppo Lepetit S.P.A. | Monoamino 2,4,5-trisubstituted oxazoles |
NZ236474A (en) * | 1989-12-20 | 1993-07-27 | Bristol Myers Squibb Co | 4,5-diphenyl-2-oxazole octanoic, nonanoic and decanoic acid and ester derivatives, preparation and pharmaceutical compositions thereof |
US5348969A (en) * | 1992-04-03 | 1994-09-20 | Bristol-Myers Squibb Company | Diphenyloxazolyl-oxazoles as platelet aggregation inhibitors |
US5763489A (en) * | 1994-03-10 | 1998-06-09 | Fujisawa Pharmaceutical Co., Ltd. | Naphthalene derivatives as prostaglandin I2 agonsists |
-
1994
- 1994-12-16 WO PCT/JP1994/002116 patent/WO1995017393A1/en active IP Right Grant
- 1994-12-16 DE DE69425162T patent/DE69425162T2/de not_active Expired - Fee Related
- 1994-12-16 ES ES95902969T patent/ES2147836T3/es not_active Expired - Lifetime
- 1994-12-16 CN CN94194557A patent/CN1046714C/zh not_active Expired - Fee Related
- 1994-12-16 PT PT95902969T patent/PT736018E/pt unknown
- 1994-12-16 CA CA002179399A patent/CA2179399A1/en not_active Abandoned
- 1994-12-16 AU AU12006/95A patent/AU686286B2/en not_active Ceased
- 1994-12-16 HU HU9601685A patent/HUT76341A/hu unknown
- 1994-12-16 RU RU96115170/04A patent/RU2176640C2/ru not_active IP Right Cessation
- 1994-12-16 AT AT95902969T patent/ATE194335T1/de not_active IP Right Cessation
- 1994-12-16 JP JP7517312A patent/JPH09506894A/ja not_active Ceased
- 1994-12-16 KR KR1019960703222A patent/KR100345943B1/ko not_active IP Right Cessation
- 1994-12-16 EP EP95902969A patent/EP0736018B1/en not_active Expired - Lifetime
- 1994-12-16 DK DK95902969T patent/DK0736018T3/da active
- 1994-12-17 TW TW083111798A patent/TW374086B/zh active
-
1998
- 1998-06-05 US US09/092,027 patent/US6025375A/en not_active Expired - Fee Related
- 1998-07-25 CN CN98116704A patent/CN1090184C/zh not_active Expired - Fee Related
-
2000
- 2000-10-04 GR GR20000402232T patent/GR3034542T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2176640C2 (ru) | 2001-12-10 |
WO1995017393A1 (en) | 1995-06-29 |
CN1138328A (zh) | 1996-12-18 |
DE69425162T2 (de) | 2000-12-21 |
DE69425162D1 (de) | 2000-08-10 |
KR960706482A (ko) | 1996-12-09 |
EP0736018B1 (en) | 2000-07-05 |
HUT76341A (en) | 1997-08-28 |
TW374086B (en) | 1999-11-11 |
ES2147836T3 (es) | 2000-10-01 |
ATE194335T1 (de) | 2000-07-15 |
DK0736018T3 (da) | 2000-09-18 |
GR3034542T3 (en) | 2001-01-31 |
AU686286B2 (en) | 1998-02-05 |
PT736018E (pt) | 2000-10-31 |
US6025375A (en) | 2000-02-15 |
KR100345943B1 (ko) | 2002-11-30 |
CN1046714C (zh) | 1999-11-24 |
CN1090184C (zh) | 2002-09-04 |
JPH09506894A (ja) | 1997-07-08 |
EP0736018A1 (en) | 1996-10-09 |
AU1200695A (en) | 1995-07-10 |
CN1229795A (zh) | 1999-09-29 |
CA2179399A1 (en) | 1995-06-29 |
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