HRP20020652A2 - Use of il-18 inhibitors - Google Patents
Use of il-18 inhibitors Download PDFInfo
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- HRP20020652A2 HRP20020652A2 HRP20020652A HRP20020652A2 HR P20020652 A2 HRP20020652 A2 HR P20020652A2 HR P20020652 A HRP20020652 A HR P20020652A HR P20020652 A2 HRP20020652 A2 HR P20020652A2
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EP (1) | EP1257292B1 (tr) |
JP (1) | JP4744763B2 (tr) |
KR (3) | KR20020086540A (tr) |
CN (1) | CN1322897C (tr) |
AT (1) | ATE506959T1 (tr) |
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BG (1) | BG66134B1 (tr) |
BR (1) | BR0108514A (tr) |
CA (2) | CA2683009C (tr) |
CY (1) | CY1111687T1 (tr) |
CZ (1) | CZ304485B6 (tr) |
DE (1) | DE60144514D1 (tr) |
DK (1) | DK1257292T3 (tr) |
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EE (1) | EE05423B1 (tr) |
HK (1) | HK1051965A1 (tr) |
HR (1) | HRP20020652A2 (tr) |
HU (1) | HU227752B1 (tr) |
IL (2) | IL151388A0 (tr) |
ME (1) | ME00546B (tr) |
MX (1) | MXPA02008079A (tr) |
NO (1) | NO331971B1 (tr) |
NZ (3) | NZ520122A (tr) |
PL (1) | PL206549B1 (tr) |
PT (1) | PT1257292E (tr) |
RS (1) | RS51737B (tr) |
SI (1) | SI1257292T1 (tr) |
SK (1) | SK288032B6 (tr) |
TR (2) | TR200502508T2 (tr) |
WO (1) | WO2001062285A1 (tr) |
Families Citing this family (25)
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KR101111103B1 (ko) * | 2000-02-10 | 2012-02-13 | 아보트 러보러터리즈 | 사람 인터류킨-18에 결합하는 항체 및 이를 제조하고 사용하는 방법 |
CN1322897C (zh) * | 2000-02-21 | 2007-06-27 | 应用研究系统Ars股份公司 | Il-18抑制剂的应用 |
AU2002211744B8 (en) | 2000-10-11 | 2008-03-20 | Viron Therapeutics, Inc. | Nucleic acid molecules and polypeptides for immune modulation |
US7718368B2 (en) | 2000-12-04 | 2010-05-18 | Viron Therapeutics Inc. | Immunomodulatory protein and useful embodiments thereof |
ES2334773T3 (es) * | 2001-05-16 | 2010-03-16 | Yeda Research And Development Co. Ltd. | Uso de inhibidores de il-18 para el tratamiento o prevencion de la sepsis. |
MXPA04002565A (es) * | 2001-11-30 | 2004-05-31 | Pfizer Prod Inc | Combinacion de un inhibidor de il-1/18 con un inhibidor de tnf para el tratamiento de inflamacion. |
WO2004064713A2 (en) * | 2003-01-20 | 2004-08-05 | Vib Vzw | The use of yop preoteins or rho gtpase inhibitors as caspase-1 inhibitors |
JP4134166B2 (ja) | 2003-04-30 | 2008-08-13 | 独立行政法人科学技術振興機構 | ヒト抗ヒトインターロイキン−18抗体およびその断片、並びにそれらの利用方法 |
WO2005047906A1 (en) * | 2003-11-10 | 2005-05-26 | Vertex Pharmaceuticals Incorporated | Methods for monitoring il-18 |
US7968684B2 (en) * | 2003-11-12 | 2011-06-28 | Abbott Laboratories | IL-18 binding proteins |
JP5069000B2 (ja) | 2004-06-30 | 2012-11-07 | 敦生 関山 | 非炎症性ストレス応答の指標剤およびその利用 |
JP5595632B2 (ja) | 2004-07-16 | 2014-09-24 | 敦生 関山 | Il−18レセプターアンタゴニスト、および当該アンタゴニストを含む薬学的組成物 |
DK1885753T3 (da) | 2005-06-03 | 2011-10-03 | Ares Trading Sa | Fremstilling af rekombinant II-18-proteiner |
PT1891088E (pt) | 2005-06-10 | 2011-12-19 | Ares Trading Sa | Processo para a purificação da proteína de ligação il-18 |
EP1746167A1 (en) * | 2005-07-20 | 2007-01-24 | Apoxis SA | Method for the identification of compounds susceptible to inhibit inflammation |
US8133978B2 (en) | 2006-05-25 | 2012-03-13 | Glaxo Group Limited | Humanised anti-interleukin-18 antibody |
US8440195B2 (en) * | 2010-11-12 | 2013-05-14 | National University Corporation Chiba University | Inhibition of CD69 for treatment of inflammatory conditions |
GB201213968D0 (en) * | 2012-08-06 | 2012-09-19 | Isis Innovation | Prevention and treatment of osteoarthritis |
SG11201601717VA (en) * | 2013-09-05 | 2016-04-28 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in inflammatory diseases |
RU2755691C2 (ru) | 2015-03-05 | 2021-09-20 | Аб2 Био Са | Il-18-связывающие белок (il-18bp) и антитела при воспалительных заболеваниях |
CN106109497A (zh) * | 2016-07-25 | 2016-11-16 | 深圳爱生再生医学科技有限公司 | 治疗肝硬化的干细胞制剂 |
CN106834449B (zh) * | 2017-01-10 | 2019-04-30 | 东南大学 | 与原发性胆汁性胆管炎关联的白细胞介素21受体及其应用 |
US20210115131A1 (en) * | 2018-06-14 | 2021-04-22 | Université De Bordeaux | Treatment of Placental Chronic Histiocytic Intervillositis Using an Inhibitor of Interleukin-1 |
WO2023286694A1 (ja) | 2021-07-13 | 2023-01-19 | 国立大学法人東海国立大学機構 | 炎症性腸疾患を治療するための医薬組成物 |
CN117647645B (zh) * | 2024-01-29 | 2024-04-12 | 中国人民解放军总医院第一医学中心 | Lbp、atf6、m-csfr联用在制备诊断自身免疫性肝病产品中的应用及试剂盒 |
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US5985863A (en) * | 1996-09-12 | 1999-11-16 | Vertex Pharmaceuticals, Inc. | Compositions and methods for decreasing IGIF and IFN-γ production by administering an ICE inhibitor |
US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
US5744451A (en) * | 1995-09-12 | 1998-04-28 | Warner-Lambert Company | N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity |
EP0936923B1 (en) * | 1996-11-15 | 2003-12-17 | Kennedy Institute Of Rheumatology | SUPPRESSION OF TNFalpha AND IL-12 IN THERAPY |
US7141393B2 (en) * | 1996-12-26 | 2006-11-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Interleukin-18-receptor proteins |
JP4026923B2 (ja) * | 1997-03-12 | 2007-12-26 | 株式会社林原生物化学研究所 | ポリペプチド |
US6087116A (en) * | 1997-03-12 | 2000-07-11 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Interleukin-18 (IL-18) receptor polypeptides and their uses |
IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
KR100537558B1 (ko) * | 1998-09-01 | 2005-12-19 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 인터류킨-18 결합 단백질 |
AR022952A1 (es) * | 1999-03-19 | 2002-09-04 | Smithkline Beecham Corp | ANTICUERPO MONOCLONAL DE ROEDOR ESPECIFICAMENTE NEUTRALIZANTE PARA LA INTERLEUQUINA-18 HUMANA , UN FRAGMENTO FAB NEUTRALIZANTE o FRAGMENTO F(AB')2, UNA REGION DE COMPLEMENTARIEDAD DE CADENA LIGERA DE INMONOGLOBULINA(CDR), UNA MOLECULA DE ACIDO NUCLEICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE, EL |
KR101111103B1 (ko) * | 2000-02-10 | 2012-02-13 | 아보트 러보러터리즈 | 사람 인터류킨-18에 결합하는 항체 및 이를 제조하고 사용하는 방법 |
CN1322897C (zh) * | 2000-02-21 | 2007-06-27 | 应用研究系统Ars股份公司 | Il-18抑制剂的应用 |
AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
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