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HK1064664A1 - Novel phenylethanolamine compounds having beta2-acceptor excitatory function and their preparation method - Google Patents

Novel phenylethanolamine compounds having beta2-acceptor excitatory function and their preparation method Download PDF

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Publication number
HK1064664A1
HK1064664A1 HK04107530A HK04107530A HK1064664A1 HK 1064664 A1 HK1064664 A1 HK 1064664A1 HK 04107530 A HK04107530 A HK 04107530A HK 04107530 A HK04107530 A HK 04107530A HK 1064664 A1 HK1064664 A1 HK 1064664A1
Authority
HK
Hong Kong
Prior art keywords
compounds
carbon atoms
amino
formula
prepared
Prior art date
Application number
HK04107530A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1064664B (en
Inventor
程卯生
潘莉
冀蕾
张莉
沈建民
宋桂兰
李志清
Original Assignee
沈阳药科大学
锦州九泰药业有限责任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 沈阳药科大学, 锦州九泰药业有限责任公司 filed Critical 沈阳药科大学
Publication of HK1064664A1 publication Critical patent/HK1064664A1/en
Publication of HK1064664B publication Critical patent/HK1064664B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/68Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK04107530.8A 2001-09-30 2002-09-25 Novel phenylethanolamine compounds having beta2-acceptor excitatory function and their preparation method HK1064664B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNB011282347A CN1276911C (zh) 2001-09-30 2001-09-30 具有β2-受体兴奋作用的新型苯乙醇胺类化合物及其制法
CN01128234 2001-09-30
PCT/CN2002/000676 WO2003093219A1 (fr) 2001-09-30 2002-09-25 Nouveaux composes de phenylethanolamine ayant une fonction d'excitation d'un $g(b)2-accepteur et leur procede de preparation

Publications (2)

Publication Number Publication Date
HK1064664A1 true HK1064664A1 (en) 2005-02-04
HK1064664B HK1064664B (en) 2007-06-29

Family

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Also Published As

Publication number Publication date
DK1439164T3 (da) 2007-08-20
JP2005519989A (ja) 2005-07-07
RU2264382C1 (ru) 2005-11-20
WO2003093219A1 (fr) 2003-11-13
AU2002338124A1 (en) 2003-11-17
AU2002338124A8 (en) 2003-11-17
ATE359261T1 (de) 2007-05-15
CN1276911C (zh) 2006-09-27
JP3990399B2 (ja) 2007-10-10
US7098364B2 (en) 2006-08-29
DE60219500T2 (de) 2007-12-13
RU2004112212A (ru) 2005-09-10
CN1408703A (zh) 2003-04-09
DE60219500D1 (de) 2007-05-24
EP1439164A4 (en) 2005-12-21
US20040266867A1 (en) 2004-12-30
EP1439164B1 (en) 2007-04-11
ES2284926T3 (es) 2007-11-16
EP1439164A1 (en) 2004-07-21

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PE Patent expired

Effective date: 20220924