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EP0540575A4 - Human meg-csf protein and methods - Google Patents

Human meg-csf protein and methods

Info

Publication number
EP0540575A4
EP0540575A4 EP19910913186 EP91913186A EP0540575A4 EP 0540575 A4 EP0540575 A4 EP 0540575A4 EP 19910913186 EP19910913186 EP 19910913186 EP 91913186 A EP91913186 A EP 91913186A EP 0540575 A4 EP0540575 A4 EP 0540575A4
Authority
EP
European Patent Office
Prior art keywords
methods
csf protein
human meg
meg
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910913186
Other versions
EP0540575A1 (en
Inventor
Martin J Murphy
Ralph E Parchment
Connie L Erickson-Miller
Wei Dr Dai
Zhao-Geng Zhang
Lance A Liotta
Henry Krutzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HIPPLE CANCER RESEARCH CENTER
HIPPLE CANCER RES CENTER
Original Assignee
HIPPLE CANCER RESEARCH CENTER
HIPPLE CANCER RES CENTER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HIPPLE CANCER RESEARCH CENTER, HIPPLE CANCER RES CENTER filed Critical HIPPLE CANCER RESEARCH CENTER
Publication of EP0540575A1 publication Critical patent/EP0540575A1/en
Publication of EP0540575A4 publication Critical patent/EP0540575A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP19910913186 1990-07-02 1991-07-02 Human meg-csf protein and methods Withdrawn EP0540575A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54757390A 1990-07-02 1990-07-02
US547573 1990-07-02

Publications (2)

Publication Number Publication Date
EP0540575A1 EP0540575A1 (en) 1993-05-12
EP0540575A4 true EP0540575A4 (en) 1994-06-08

Family

ID=24185193

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910913186 Withdrawn EP0540575A4 (en) 1990-07-02 1991-07-02 Human meg-csf protein and methods

Country Status (7)

Country Link
EP (1) EP0540575A4 (en)
JP (1) JPH06502621A (en)
KR (1) KR930701475A (en)
AU (1) AU8215591A (en)
CA (1) CA2086248A1 (en)
FI (1) FI925983A (en)
WO (1) WO1992000319A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260417A (en) * 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
US5766581A (en) * 1994-03-31 1998-06-16 Amgen Inc. Method for treating mammals with monopegylated proteins that stimulates megakaryocyte growth and differentiation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003397A1 (en) * 1988-09-21 1990-04-05 Meiji Seika Kaisha, Ltd. Novel megakaryocytic colony stimulating factor and process for its preparation
WO1991002001A1 (en) * 1989-08-08 1991-02-21 Genetics Institute, Inc. A megakaryocytopoietic factor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894440A (en) * 1986-09-17 1990-01-16 Massachusetts Institute Of Technology Method of isolating megakaryocyte stimulatory factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003397A1 (en) * 1988-09-21 1990-04-05 Meiji Seika Kaisha, Ltd. Novel megakaryocytic colony stimulating factor and process for its preparation
EP0516845A1 (en) * 1988-09-21 1992-12-09 Meiji Seika Kaisha Ltd. Novel megakaryocytic colony stimulating factor and process for its preparation
WO1991002001A1 (en) * 1989-08-08 1991-02-21 Genetics Institute, Inc. A megakaryocytopoietic factor

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
INTERNATIONAL CAPRI CONFERENCE, OCTOBER 6-12 , 1989 *
K. OGATA ET AL: "Partial purification and characterization of human Megakaryocyte colony-stimulating factor ( Meg-CSF )", INTERNATIONAL JOURNAL OF CELL CLONING, vol. 8, 1990, pages 103 - 120, XP000917130 *
See also references of WO9200319A1 *
SHIMIZU T. ET AL: "Purification of human megakaryocyte colony-stimulating factor", EXPERIMENTAL HEMATOLOGY, vol. 14, no. 6, July 1986 (1986-07-01), pages 490 *
SHIMIZU T. ET AL: "purification of human sialylated megakaryocyte colony-stimulating factor", EXPERIMENTAL HEMATOLOGY, vol. 15, no. 5, August 1987 (1987-08-01), pages 492, XP000645923 *
ZHANG Z. G. ET AL: "Further purification of megakaryocyte colony stimulating factor ( Meg-CSF ) from the urine of patients with aplastic anemia", EXPERIMENTAL HEMATOLOGY, vol. 19, no. 6, 21 July 1991 (1991-07-21), pages 493 *

Also Published As

Publication number Publication date
CA2086248A1 (en) 1992-01-03
EP0540575A1 (en) 1993-05-12
KR930701475A (en) 1993-06-11
FI925983A0 (en) 1992-12-31
AU8215591A (en) 1992-01-23
WO1992000319A1 (en) 1992-01-09
JPH06502621A (en) 1994-03-24
FI925983A (en) 1992-12-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19930104

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ERICKSON-MILLER, CONNIE, L.

Inventor name: LIOTTA, LANCE, A.

Inventor name: PARCHMENT, RALPH, E.

Inventor name: KRUTZSCH, HENRY

Inventor name: DAI, WEI, DR.

Inventor name: ZHANG, ZHAO-GENG

Inventor name: MURPHY, MARTIN, J.

RHK1 Main classification (correction)

Ipc: C12N 15/27

A4 Supplementary search report drawn up and despatched

Effective date: 19940420

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

17Q First examination report despatched

Effective date: 19950310

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19951023