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EA200401390A1 - N-ацетилглюкозамин-6-фосфатдеацетилаза человека, взаимодействующая с каспазой-8, и способы ее применения - Google Patents

N-ацетилглюкозамин-6-фосфатдеацетилаза человека, взаимодействующая с каспазой-8, и способы ее применения

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Publication number
EA200401390A1
EA200401390A1 EA200401390A EA200401390A EA200401390A1 EA 200401390 A1 EA200401390 A1 EA 200401390A1 EA 200401390 A EA200401390 A EA 200401390A EA 200401390 A EA200401390 A EA 200401390A EA 200401390 A1 EA200401390 A1 EA 200401390A1
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EA
Eurasian Patent Office
Prior art keywords
protein
caspase
antibody
acetylglycosamin
interacting
Prior art date
Application number
EA200401390A
Other languages
English (en)
Other versions
EA007273B1 (ru
Inventor
Дэвид Уоллах
Маркус Шухманн
Таня Гончаров
Original Assignee
Йеда Рисерч Энд Дивелопмент Ко.Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12772198A external-priority patent/IL127721A0/xx
Application filed by Йеда Рисерч Энд Дивелопмент Ко.Лтд. filed Critical Йеда Рисерч Энд Дивелопмент Ко.Лтд.
Publication of EA200401390A1 publication Critical patent/EA200401390A1/ru
Publication of EA007273B1 publication Critical patent/EA007273B1/ru

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Abstract

Изобретение относится к биотехнологии и раскрывает белки, взаимодействующие с каспазой-8, в частности, к N-ацетилглюкозамин-6-фосфатдеацетилазе человека или к ее вариантам. Изобретение также раскрывает последовательность ДНК, кодирующей белок по изобретению. Представлены вектор, содержащий указанную ДНК, и клетка-хозяин, которая может продуцировать указанный белок. Представлены специфический для указанной ДНК рибозим, а также антисмысловой олигонуклеотид и антитело к заявленному белку. Белок, рибозим, антитело используются для модуляции активности каспазы-8, апоптоза и, соответственно, для лечения ряда заболеваний, связанных с каспазой-8. Антитело против указанного белка может использоваться в иммуноанализе, а сам белок - для идентификации и выделения белков с подобной активностью.Отчет о международном поиске был опубликован 2001.08.23.
EA200401390A 1998-12-24 1999-12-23 Выделенный полипептид, связывающийся с каспазой -8, и способы его применения EA007273B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL12772198A IL127721A0 (en) 1998-12-24 1998-12-24 Caspase-8 interacting proteins
IL13210599A IL132105A0 (en) 1998-12-24 1999-09-28 Caspase-8 interacting proteins

Publications (2)

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EA200401390A1 true EA200401390A1 (ru) 2005-02-24
EA007273B1 EA007273B1 (ru) 2006-08-25

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EA200000875A EA005853B1 (ru) 1998-12-24 1999-12-23 N-ацетилглюкозамин-6-фосфатдеацетилаза человека, взаимодействующая с каспазой-8, и способы ее применения
EA200401390A EA007273B1 (ru) 1998-12-24 1999-12-23 Выделенный полипептид, связывающийся с каспазой -8, и способы его применения

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CN106146665B (zh) * 2016-08-31 2019-08-09 中国农业科学院植物保护研究所 一种用于制备针对甜菜夜蛾caspase-5大亚基的抗体的方法
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US20040229260A1 (en) 2004-11-18
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CA2321672A1 (en) 2000-07-06
WO2000039160A3 (ru) 2001-08-23
EE200000487A (et) 2002-02-15
BG65375B1 (bg) 2008-04-30
IL138025A (en) 2007-08-19
NO20004167L (no) 2000-10-19
KR100646075B1 (ko) 2006-11-15
EA007273B1 (ru) 2006-08-25
KR100646074B1 (ko) 2006-11-13
CN1223608C (zh) 2005-10-19
IL132105A0 (en) 2001-03-19
AU780585B2 (en) 2005-04-07
NO20004167D0 (no) 2000-08-21
SK12682000A3 (sk) 2001-03-12
US6762283B1 (en) 2004-07-13
US20080139476A1 (en) 2008-06-12
AU1795000A (en) 2000-07-31
BG104707A (en) 2001-04-30
NZ506477A (en) 2003-08-29
PL350181A1 (en) 2002-11-18
EA200000875A1 (ru) 2001-10-22
AR029321A1 (es) 2003-06-25
BG109904A (bg) 2008-01-31
EA005853B1 (ru) 2005-06-30
CN1298411A (zh) 2001-06-06
WO2000039160A2 (en) 2000-07-06

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