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DK567084A - Gnrh-antagonister - Google Patents

Gnrh-antagonister Download PDF

Info

Publication number
DK567084A
DK567084A DK567084A DK567084A DK567084A DK 567084 A DK567084 A DK 567084A DK 567084 A DK567084 A DK 567084A DK 567084 A DK567084 A DK 567084A DK 567084 A DK567084 A DK 567084A
Authority
DK
Denmark
Prior art keywords
phe
arg
2nal
gonads
steroids
Prior art date
Application number
DK567084A
Other languages
English (en)
Other versions
DK164409B (da
DK164409C (da
DK567084D0 (da
Inventor
Roger William Roeske
Jean Edouard Frederic Rivier
Jr Wylie Walker Vale
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of DK567084D0 publication Critical patent/DK567084D0/da
Publication of DK567084A publication Critical patent/DK567084A/da
Publication of DK164409B publication Critical patent/DK164409B/da
Application granted granted Critical
Publication of DK164409C publication Critical patent/DK164409C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DK567084A 1983-11-29 1984-11-29 Lhrh-antagonister og ikke-toksiske salte deraf samt farmaceutisk middel indeholdende disse DK164409C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55614883 1983-11-29
US06/556,148 US4547370A (en) 1983-11-29 1983-11-29 GnRH Antagonists

Publications (4)

Publication Number Publication Date
DK567084D0 DK567084D0 (da) 1984-11-29
DK567084A true DK567084A (da) 1985-05-30
DK164409B DK164409B (da) 1992-06-22
DK164409C DK164409C (da) 1992-11-09

Family

ID=24220086

Family Applications (1)

Application Number Title Priority Date Filing Date
DK567084A DK164409C (da) 1983-11-29 1984-11-29 Lhrh-antagonister og ikke-toksiske salte deraf samt farmaceutisk middel indeholdende disse

Country Status (18)

Country Link
US (2) US4547370A (da)
EP (1) EP0143573B1 (da)
JP (1) JPH0689037B2 (da)
KR (1) KR900007083B1 (da)
AT (1) ATE39701T1 (da)
AU (1) AU571595B2 (da)
CA (1) CA1262399A (da)
DD (1) DD235874A5 (da)
DE (1) DE3475910D1 (da)
DK (1) DK164409C (da)
ES (1) ES8604265A1 (da)
GR (1) GR81042B (da)
HU (1) HU200785B (da)
IE (1) IE57910B1 (da)
IL (1) IL73364A0 (da)
PH (1) PH19971A (da)
PT (1) PT79473A (da)
ZA (1) ZA848305B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
US4740500A (en) * 1985-01-31 1988-04-26 The Salk Institute For Biological Studies GnRH antagonists VIII
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
WO1988007056A1 (en) * 1987-03-10 1988-09-22 Eastern Virginia Medical Authority METHOD AND KIT FOR CONTRACEPTION WITH GnRH-ANTAGONIST AND PROGESTIN
US4851385A (en) * 1987-07-15 1989-07-25 Indiana University Foundation LHRH antagonist analogs having low histamine-release activity
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
DE68928278T2 (de) * 1988-02-10 1998-03-12 Tap Pharmaceuticals Inc Lhrh-analog
US5480969A (en) * 1992-09-15 1996-01-02 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US5656727A (en) * 1992-09-15 1997-08-12 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
US5932547A (en) 1996-07-03 1999-08-03 Alza Corporation Non-aqueous polar aprotic peptide formulations
US5916582A (en) * 1996-07-03 1999-06-29 Alza Corporation Aqueous formulations of peptides
US5981489A (en) * 1996-07-18 1999-11-09 Alza Corporation Non-aqueous protic peptide formulations
US5968895A (en) 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US5925730A (en) * 1997-04-11 1999-07-20 Ferring Bv GnRH antagonists
US6217844B1 (en) 1998-04-27 2001-04-17 Praecis Pharmaceuticals, Inc. Methods for detecting lesions in dense breast tissue using LHRH antagonists
US6455499B1 (en) 1999-02-23 2002-09-24 Indiana University Foundation Methods for treating disorders associated with LHRH activity
US6598784B2 (en) * 2000-12-20 2003-07-29 Meadwestvaco Packaging Syatens, Llc Beverage carton with strap type carrying handle
AU2002235348A1 (en) * 2001-01-17 2002-07-30 Praecis Pharmaceuticals Inc. Methods for treating hormone associated conditions using a combination of lhrh antagonists and specific estrogen receptor modulators
GB0320806D0 (en) 2003-09-05 2003-10-08 Astrazeneca Ab Therapeutic treatment
US20060003008A1 (en) 2003-12-30 2006-01-05 Gibson John W Polymeric devices for controlled release of active agents
PL2078032T3 (pl) 2006-10-24 2018-01-31 Repros Therapeutics Inc Kompozycje i sposoby do hamowania proliferacji endometrium
EP3600373A1 (en) 2017-03-31 2020-02-05 Institut National de la Santé et de la Recherche Medicale A gnrh antagonist for use in the treatment of a women affected with polycystic ovary syndrome

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4317815A (en) * 1979-06-13 1982-03-02 Coy David Howard LH-RH Antagonists
US4253997A (en) * 1979-12-17 1981-03-03 American Home Products Corporation Anti-ovulatory decapeptides
NZ196558A (en) * 1980-04-15 1984-10-19 Salk Inst For Biological Studi Lrf antagonists and pharmaceutical compositions
US4409208A (en) * 1980-04-15 1983-10-11 The Salk Institute For Biological Studies GnRH antagonists
EP0041286B1 (en) * 1980-06-02 1984-08-15 Andrew Victor Schally Lh-rh antagonists
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists

Also Published As

Publication number Publication date
IE843043L (en) 1985-05-29
ES538035A0 (es) 1986-01-16
AU571595B2 (en) 1988-04-21
PT79473A (en) 1984-12-01
DK164409B (da) 1992-06-22
CA1262399A (en) 1989-10-17
ES8604265A1 (es) 1986-01-16
JPS60136598A (ja) 1985-07-20
ATE39701T1 (de) 1989-01-15
DD235874A5 (de) 1986-05-21
HUT36143A (en) 1985-08-28
DE3475910D1 (en) 1989-02-09
DK164409C (da) 1992-11-09
HU200785B (en) 1990-08-28
KR850004113A (ko) 1985-07-01
EP0143573A1 (en) 1985-06-05
US4689396A (en) 1987-08-25
US4547370A (en) 1985-10-15
GR81042B (en) 1985-03-27
IE57910B1 (en) 1993-05-05
ZA848305B (en) 1985-06-26
IL73364A0 (en) 1985-01-31
KR900007083B1 (ko) 1990-09-28
JPH0689037B2 (ja) 1994-11-09
DK567084D0 (da) 1984-11-29
EP0143573B1 (en) 1989-01-04
PH19971A (en) 1986-08-26
AU3472484A (en) 1985-06-06

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Legal Events

Date Code Title Description
PBP Patent lapsed