CS216933B2 - Method of making the heterocyclic phenoxyemines - Google Patents

Method of making the heterocyclic phenoxyemines Download PDF

Info

Publication number: CS216933B2
Authority: CS; Czechoslovakia
Prior art keywords: pyrrolidine; methoxy; compounds; mol; dried
Prior art date: 1979-07-06

Application number

CS804693A

Other languages

Czech (cs)

English (en)

Inventor

Michel Thominet

Jacqueline Franceschini

Original Assignee

Ile De France

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-07-06

Filing date

1980-07-01

Publication date

1982-12-31

1979-07-06 Priority claimed from FR7917610A external-priority patent/FR2460935A1/fr

1980-04-01 Priority claimed from FR8007352A external-priority patent/FR2479218A2/fr

1980-07-01 Application filed by Ile De France filed Critical Ile De France

1981-02-12 Priority to CS811017A priority Critical patent/CS216934B2/cs

1982-12-31 Publication of CS216933B2 publication Critical patent/CS216933B2/cs

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

CS804693A 1979-07-06 1980-07-01 Method of making the heterocyclic phenoxyemines CS216933B2 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CS811017A CS216934B2 (cs)	1980-07-01	1981-02-12	Způsob výroby l-cyklohexenylmethyl-2-chIorethylpyrrolidinu

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7917610A FR2460935A1 (fr)	1979-07-06	1979-07-06	Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthetiques locaux
FR8007352A FR2479218A2 (fr)	1980-04-01	1980-04-01	Nouvelles phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthesiques locaux

Publications (1)

Publication Number	Publication Date
CS216933B2 true CS216933B2 (en)	1982-12-31

Family

ID=26221244

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS804693A CS216933B2 (en)	1979-07-06	1980-07-01	Method of making the heterocyclic phenoxyemines

Country Status (37)

Country	Link
US (1)	US4379161A (it)
EP (2)	EP0094102B1 (it)
JP (2)	JPS5639065A (it)
AR (1)	AR224012A1 (it)
AT (2)	ATE10739T1 (it)
AU (2)	AU536482B2 (it)
BE (1)	BE884124A (it)
BG (2)	BG35746A3 (it)
CA (1)	CA1163273A (it)
CH (2)	CH648827A5 (it)
CS (1)	CS216933B2 (it)
DD (2)	DD153206A5 (it)
DE (2)	DE3069789D1 (it)
DK (1)	DK157538C (it)
ES (1)	ES8103049A1 (it)
FI (2)	FI74274C (it)
GR (1)	GR69638B (it)
HK (2)	HK55889A (it)
HU (2)	HU186539B (it)
IE (2)	IE50060B1 (it)
IL (2)	IL60472A (it)
IN (2)	IN153037B (it)
IT (1)	IT1188985B (it)
JO (1)	JO1077B1 (it)
LU (1)	LU82584A1 (it)
MA (1)	MA18893A1 (it)
MX (2)	MX6366E (it)
NO (2)	NO156086C (it)
NZ (1)	NZ194230A (it)
OA (1)	OA06561A (it)
PH (1)	PH16449A (it)
PL (1)	PL127393B1 (it)
PT (1)	PT71482A (it)
RO (2)	RO81532B (it)
SU (1)	SU1085507A3 (it)
YU (2)	YU42344B (it)
ZW (1)	ZW15280A1 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2586018B1 (fr) *	1985-08-12	1988-03-25	Ile De France	Nouveau benzodioxepanne, son procede de synthese et ses applications en therapeutique
WO1990012004A1 (en) *	1989-04-07	1990-10-18	Fujisawa Pharmaceutical Co., Ltd.	New naphthalene compounds and method of producing the same
EP0471941A3 (en) *	1990-08-16	1992-10-14	American Cyanamid Company	An improved process for the preparation of 5-bromo-2-methoxyresorcinol
US5472958A (en) *	1994-08-29	1995-12-05	Abbott Laboratories	2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function
US7799337B2 (en)	1997-07-21	2010-09-21	Levin Bruce H	Method for directed intranasal administration of a composition
DE69817214T2 (de) *	1997-11-05	2004-06-09	Neurosearch A/S	Azaring-ether-derivate und ihre verwendung als nicotinic-ach-rezeptormodulatoren
US8473062B2 (en) *	2008-05-01	2013-06-25	Autonomic Technologies, Inc.	Method and device for the treatment of headache
US8412336B2 (en)	2008-12-29	2013-04-02	Autonomic Technologies, Inc.	Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) *	2009-01-15	2016-04-26	Autonomic Technologies, Inc.	Approval per use implanted neurostimulator
US8494641B2 (en)	2009-04-22	2013-07-23	Autonomic Technologies, Inc.	Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US20100185249A1 (en) *	2009-01-22	2010-07-22	Wingeier Brett M	Method and Devices for Adrenal Stimulation
CN111205015B (zh) *	2020-01-20	2021-11-26	东南大学	一种高稳定泡沫混凝土发泡剂的制备方法

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Publication number	Priority date	Publication date	Assignee	Title
DE543876C (de) *	1928-04-25	1932-02-11	C H Boehringer Sohn Akt Ges	Verfahren zur Darstellung von Piperidinalkinen
US3117976A (en) *	1958-11-12	1964-01-14	Beecham Res Lab	Nu-alkyl-pyrrolidine-2-methanol, alpha cyclohexyl mandelates
FR1342756A (fr) *	1958-11-21	1963-11-15	Beecham Res Lab	Esters basiques et leur procédé de préparation, notamment le phényl-cyclohexyl-glycolate de (1-méthyl-2-pyrrolidyl) méthyle et ses sels d'addition
GB1096441A (en) *	1964-01-15	1967-12-29	Bristol Myers Co	Ethers of benzyl phenols and a process for the preparation thereof
US3904622A (en) *	1968-02-16	1975-09-09	Ile De France	Dialkylaminoalkyl ethers of 2-alkoxy-3,5-dihalobenzene
GB1268951A (en) *	1969-06-12	1972-03-29	Pfizer Ltd	Phenoxy-amines
FR2155927A1 (en) *	1971-10-15	1973-05-25	Synthelabo	1-phenylcyclo hexane carboxylic acid esters - with antispasmodic and anticholinergic activity
JPS5139661A (en) *	1974-09-27	1976-04-02	Nippon Kayaku Kk	Kogakukatsusei 11 mechiru 22 * beetaaa hidorokishechiru * pirorijin oyobisono chukantaino seizoho
JPS5251362A (en) *	1975-10-20	1977-04-25	Teijin Ltd	Preparation of optically active pyrrolidine derivatives
LU78625A1 (de) *	1977-12-02	1979-06-13	Byk Gulden Lomberg Chem Fab	Substituierte 1-phenyl-2-pyrrolidin-2-yl-ethanole,verfahren zu ihrer herstellung,ihre verwendung und sie enthaltende arzneimittel
DE2811952A1 (de) *	1978-03-18	1979-10-31	Merck Patent Gmbh	Phenoxyalkylamine und verfahren zu ihrer herstellung

1980
- 1980-06-25 US US06/162,796 patent/US4379161A/en not_active Expired - Lifetime
- 1980-07-01 AT AT80400999T patent/ATE10739T1/de not_active IP Right Cessation
- 1980-07-01 EP EP83105420A patent/EP0094102B1/fr not_active Expired
- 1980-07-01 BG BG062115A patent/BG35746A3/xx unknown
- 1980-07-01 EP EP80400999A patent/EP0024960B1/fr not_active Expired
- 1980-07-01 YU YU1710/80A patent/YU42344B/xx unknown
- 1980-07-01 DE DE8080400999T patent/DE3069789D1/de not_active Expired
- 1980-07-01 AT AT83105420T patent/ATE17119T1/de not_active IP Right Cessation
- 1980-07-01 SU SU802938255A patent/SU1085507A3/ru active
- 1980-07-01 BG BG048341A patent/BG35039A3/xx unknown
- 1980-07-01 CS CS804693A patent/CS216933B2/cs unknown
- 1980-07-01 DE DE8383105420T patent/DE3071314D1/de not_active Expired
- 1980-07-01 OA OA57149A patent/OA06561A/xx unknown
- 1980-07-02 IL IL60472A patent/IL60472A/xx unknown
- 1980-07-02 BE BE1/9873A patent/BE884124A/fr not_active IP Right Cessation
- 1980-07-02 AU AU60028/80A patent/AU536482B2/en not_active Ceased
- 1980-07-02 PT PT71482A patent/PT71482A/pt unknown
- 1980-07-03 AR AR281635A patent/AR224012A1/es active
- 1980-07-03 RO RO101590A patent/RO81532B/ro unknown
- 1980-07-03 RO RO110029A patent/RO85323B/ro unknown
- 1980-07-03 HU HU822217A patent/HU186539B/hu not_active IP Right Cessation
- 1980-07-03 HU HU80801658A patent/HU181147B/hu not_active IP Right Cessation
- 1980-07-03 NZ NZ194230A patent/NZ194230A/xx unknown
- 1980-07-04 LU LU82584A patent/LU82584A1/fr unknown
- 1980-07-04 CH CH5169/80A patent/CH648827A5/fr not_active IP Right Cessation
- 1980-07-04 DK DK289580A patent/DK157538C/da not_active IP Right Cessation
- 1980-07-04 MA MA19091A patent/MA18893A1/fr unknown
- 1980-07-04 NO NO802027A patent/NO156086C/no unknown
- 1980-07-04 FI FI802156A patent/FI74274C/fi not_active IP Right Cessation
- 1980-07-04 ZW ZW152/80A patent/ZW15280A1/xx unknown
- 1980-07-04 CH CH5684/84A patent/CH655100A5/fr not_active IP Right Cessation
- 1980-07-04 MX MX80100439U patent/MX6366E/es unknown
- 1980-07-04 IE IE1392/80A patent/IE50060B1/en not_active IP Right Cessation
- 1980-07-04 IE IE1653/85A patent/IE50061B1/en not_active IP Right Cessation
- 1980-07-04 MX MX8011334U patent/MX7642E/es unknown
- 1980-07-04 IT IT49163/80A patent/IT1188985B/it active
- 1980-07-04 GR GR62381A patent/GR69638B/el unknown
- 1980-07-04 PL PL1980225473A patent/PL127393B1/pl unknown
- 1980-07-04 ES ES493111A patent/ES8103049A1/es not_active Expired
- 1980-07-04 FI FI872955A patent/FI872955A0/fi not_active Application Discontinuation
- 1980-07-05 IN IN779/CAL/80A patent/IN153037B/en unknown
- 1980-07-05 JO JO19801077A patent/JO1077B1/en active
- 1980-07-07 DD DD222455A patent/DD153206A5/de unknown
- 1980-07-07 JP JP9321680A patent/JPS5639065A/ja active Granted
- 1980-07-07 PH PH24248A patent/PH16449A/en unknown
- 1980-07-07 DD DD80234984A patent/DD201141A5/de not_active IP Right Cessation
- 1980-09-30 JP JP13751280A patent/JPS5649351A/ja active Granted
1982
- 1982-12-16 CA CA000417963A patent/CA1163273A/fr not_active Expired
- 1982-12-17 YU YU2801/82A patent/YU42824B/xx unknown
1983
- 1983-06-01 IL IL68854A patent/IL68854A0/xx not_active IP Right Cessation
- 1983-10-10 IN IN1246/CAL/83A patent/IN158706B/en unknown
1984
- 1984-03-02 AU AU25260/84A patent/AU563009B2/en not_active Ceased
1986
- 1986-05-20 NO NO861988A patent/NO861988L/no unknown
1989
- 1989-07-13 HK HK558/89A patent/HK55889A/xx unknown
- 1989-07-13 HK HK556/89A patent/HK55689A/xx unknown

Also Published As

Publication number	Publication date
YU171080A (en)	1983-06-30
MX6366E (es)	1985-05-21
NO156086C (no)	1987-07-22
IT8049163A0 (it)	1980-07-04
EP0094102A2 (fr)	1983-11-16
JPS5639065A (en)	1981-04-14
OA06561A (fr)	1981-07-31
HU186539B (en)	1985-08-28
IT1188985B (it)	1988-01-28
BG35039A3 (bg)	1984-01-16
DK157538B (da)	1990-01-22
IE50060B1 (en)	1986-02-05
AU2526084A (en)	1984-07-26
IT8049163A1 (it)	1982-01-04
RO81532A (ro)	1983-04-29
DD201141A5 (de)	1983-07-06
LU82584A1 (fr)	1981-02-02
AU536482B2 (en)	1984-05-10
IL60472A0 (en)	1980-09-16
JPS5649351A (en)	1981-05-02
JO1077B1 (en)	1982-07-10
BE884124A (fr)	1981-01-05
ATE17119T1 (de)	1986-01-15
PL225473A1 (it)	1981-10-16
GR69638B (it)	1982-07-06
IL60472A (en)	1983-09-30
FI74274C (fi)	1988-01-11
ES493111A0 (es)	1981-02-16
EP0094102A3 (en)	1984-04-11
JPH0122264B2 (it)	1989-04-25
PH16449A (en)	1983-10-12
NO156086B (no)	1987-04-13
FI872955L (fi)	1987-07-03
JPH0149704B2 (it)	1989-10-25
IE801392L (en)	1981-01-06
DE3071314D1 (en)	1986-02-06
MX7642E (es)	1990-05-16
IN153037B (it)	1984-05-26
YU42824B (en)	1988-12-31
IE50061B1 (en)	1986-02-05
AU563009B2 (en)	1987-06-25
EP0024960A3 (en)	1981-06-17
EP0024960B1 (fr)	1984-12-12
ATE10739T1 (de)	1984-12-15
PL127393B1 (en)	1983-10-31
RO85323A (ro)	1984-09-29
DK157538C (da)	1990-06-11
DK289580A (da)	1981-01-07
BG35746A3 (bg)	1984-06-15
HK55689A (en)	1989-07-21
ES8103049A1 (es)	1981-02-16
IL68854A0 (en)	1983-10-31
YU42344B (en)	1988-08-31
US4379161A (en)	1983-04-05
DE3069789D1 (en)	1985-01-24
MA18893A1 (fr)	1981-04-01
CH655100A5 (fr)	1986-03-27
FI74274B (fi)	1987-09-30
YU280182A (en)	1983-06-30
AU6002880A (en)	1981-01-15
FI872955A7 (fi)	1987-07-03
CH648827A5 (fr)	1985-04-15
DD153206A5 (de)	1981-12-30
CA1163273A (fr)	1984-03-06
NO802027L (no)	1981-01-07
NO861988L (no)	1981-01-07
ZW15280A1 (en)	1980-10-01
HK55889A (en)	1989-07-21
SU1085507A3 (ru)	1984-04-07
RO81532B (ro)	1983-04-30
FI872955A0 (fi)	1987-07-03
EP0094102B1 (fr)	1985-12-27
AR224012A1 (es)	1981-10-15
IN158706B (it)	1987-01-10
IE801390L (en)	1981-01-04
PT71482A (fr)	1980-08-01
FI802156A7 (fi)	1981-01-07
EP0024960A2 (fr)	1981-03-11
RO85323B (ro)	1984-10-30
HU181147B (en)	1983-06-28
NZ194230A (en)	1983-02-15

Publication	Publication Date	Title
CS216933B2 (en)	1982-12-31	Method of making the heterocyclic phenoxyemines
NL8003601A (nl)	1981-01-13	Amino-etheroxyden, werkwijze voor de bereiding hiervan en de toepassing als geneesmiddel.
DE3402060A1 (de)	1985-08-01	Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
PT87854B (pt)	1992-10-30	Processo para a preparacao de derivados de tio-ureia
DE2711981A1 (de)	1977-09-29	Phenaethylaminderivate und diese verbindungen enthaltende bronchodilatorisch wirksame arzneimittel
DD283602A5 (de)	1990-10-17	Verfahren zur herstellung von verbindungen und deren verwendung
CA1139763A (fr)	1983-01-18	Procede d'obtention de nouveaux aryltrifluoroethanols
DE2348973B2 (de)	1979-08-16	1 -(m-Trifluormethylphenyl)-4-propylpiperazin-derivate, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
PT100216B (pt)	1999-06-30	N-{{4,5-di-hidroxi- e 4,5,8-tri-hidroxi-9,10-di-hidro-9,10-dioxo-2-antracentil} carbonil}-aminoacidos uteis na terapia de afeccoes osteoarticulares, processo para a sua preparacao e composicoes farmaceuticas que os contem
DE2909742A1 (de)	1979-09-27	Neue derivate des phenyl-alanins, deren herstellung, sowie deren therapeutische verwendung
US4695589A (en)	1987-09-22	Alpha-(aminoalkyl-4-hydroxy-3-(alkylthio)benzenemethanols
DE2026080B2 (de)	1979-03-22	5-Methyl-10-( ß -alkylaminoäthyl)- dibenzothiazepine, Verfahren zu ihrer Herstellung sowie pharmazeutische Zusammensetzungen
US4594428A (en)	1986-06-10	Novel substituted heterocyclic amines and methods of preparation thereof
JPH037670B2 (it)	1991-02-04
US4333930A (en)	1982-06-08	Orthoarylideneaminophenethylamines and pharmaceutical compositions
DE2618936B2 (de)	1978-09-07	N-Acyl-glutamine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitungen
KR840001238B1 (ko)	1984-08-23	신규 치환 헤테로사이클 페녹시아민의 제조방법
DE1593392C3 (de)	1979-03-15	Neue vom 9,10-Äthano-9,10-dihydroanthracen abgeleitete Aminoäther und deren Salze sowie Verfahren zu ihrer Herstellung
DE2854341A1 (de)	1979-06-28	Neue derivate der 2- eckige klammer auf (4-chinolinyl)-amino eckige klammer zu -5-fluorbenzoesaeure, verfahren zu deren herstellung, deren verwendung als arzneimittel und die sie enthaltenden pharmazeutischen zusammensetzungen
DE1595870A1 (de)	1970-03-12	Verfahren zur Herstellung von 3-(o-Methoxyphenoxy)-1,2-propandiolnicotinaten und deren Salzen
CA1161435A (fr)	1984-01-31	Phenoxyamines heterocycliques substituees, leur methode de preparation et leur application comme anesthesiques locaux
DE1901167C3 (de)	1977-11-03	Substituierte Indole, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
Gardner et al.	1933	Some New Local Anesthetics Containing the Morpholine Ring. II1
CH635584A5 (en)	1983-04-15	Process for preparing novel benzoylpiperidylalkyl indoles and related compounds
Cohen et al.	1952	840. Synthetical experiments in the B group of vitamins. Part VI. Synthesis of the pyridoxine analogue, 2-benzyl-3-hydroxy-4: 5-bis-hydroxymethylpyridine