CO5070601A1 - Suspencion peroral de meloxicam micronizado que cuenta con bajas proporciones de dioxido de silicio y un polimero hidrofilico como hidroxietilcelulosa, en un medio de dispercion constituido por una solucion reguladora en un rango de ph de 2 a 4 - Google Patents
Suspencion peroral de meloxicam micronizado que cuenta con bajas proporciones de dioxido de silicio y un polimero hidrofilico como hidroxietilcelulosa, en un medio de dispercion constituido por una solucion reguladora en un rango de ph de 2 a 4Info
- Publication number
- CO5070601A1 CO5070601A1 CO99018550A CO99018550A CO5070601A1 CO 5070601 A1 CO5070601 A1 CO 5070601A1 CO 99018550 A CO99018550 A CO 99018550A CO 99018550 A CO99018550 A CO 99018550A CO 5070601 A1 CO5070601 A1 CO 5070601A1
- Authority
- CO
- Colombia
- Prior art keywords
- acid
- pharmaceutically acceptable
- suspention
- peroral
- range
- Prior art date
Links
- ZRVUJXDFFKFLMG-UHFFFAOYSA-N Meloxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=NC=C(C)S1 ZRVUJXDFFKFLMG-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001929 meloxicam Drugs 0.000 title abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 title 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 title 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
- 239000000377 silicon dioxide Substances 0.000 title 1
- 235000012239 silicon dioxide Nutrition 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 7
- 150000003839 salts Chemical class 0.000 abstract 6
- -1 Thioxaprofen Chemical compound 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- RJMIEHBSYVWVIN-LLVKDONJSA-N (2r)-2-[4-(3-oxo-1h-isoindol-2-yl)phenyl]propanoic acid Chemical compound C1=CC([C@H](C(O)=O)C)=CC=C1N1C(=O)C2=CC=CC=C2C1 RJMIEHBSYVWVIN-LLVKDONJSA-N 0.000 abstract 1
- RDJGLLICXDHJDY-NSHDSACASA-N (2s)-2-(3-phenoxyphenyl)propanoic acid Chemical compound OC(=O)[C@@H](C)C1=CC=CC(OC=2C=CC=CC=2)=C1 RDJGLLICXDHJDY-NSHDSACASA-N 0.000 abstract 1
- MDKGKXOCJGEUJW-VIFPVBQESA-N (2s)-2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid Chemical compound C1=CC([C@@H](C(O)=O)C)=CC=C1C(=O)C1=CC=CS1 MDKGKXOCJGEUJW-VIFPVBQESA-N 0.000 abstract 1
- TYCOFFBAZNSQOJ-UHFFFAOYSA-N 2-[4-(3-fluorophenyl)phenyl]propanoic acid Chemical compound C1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC(F)=C1 TYCOFFBAZNSQOJ-UHFFFAOYSA-N 0.000 abstract 1
- JIEKMACRVQTPRC-UHFFFAOYSA-N 2-[4-(4-chlorophenyl)-2-phenyl-5-thiazolyl]acetic acid Chemical compound OC(=O)CC=1SC(C=2C=CC=CC=2)=NC=1C1=CC=C(Cl)C=C1 JIEKMACRVQTPRC-UHFFFAOYSA-N 0.000 abstract 1
- XKSAJZSJKURQRX-UHFFFAOYSA-N 2-acetyloxy-5-(4-fluorophenyl)benzoic acid Chemical compound C1=C(C(O)=O)C(OC(=O)C)=CC=C1C1=CC=C(F)C=C1 XKSAJZSJKURQRX-UHFFFAOYSA-N 0.000 abstract 1
- ILYSAKHOYBPSPC-UHFFFAOYSA-N 2-phenylbenzoic acid Chemical class OC(=O)C1=CC=CC=C1C1=CC=CC=C1 ILYSAKHOYBPSPC-UHFFFAOYSA-N 0.000 abstract 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 1
- MNIPYSSQXLZQLJ-UHFFFAOYSA-N Biofenac Chemical compound OC(=O)COC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl MNIPYSSQXLZQLJ-UHFFFAOYSA-N 0.000 abstract 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 1
- SBDNJUWAMKYJOX-UHFFFAOYSA-N Meclofenamic Acid Chemical compound CC1=CC=C(Cl)C(NC=2C(=CC=CC=2)C(O)=O)=C1Cl SBDNJUWAMKYJOX-UHFFFAOYSA-N 0.000 abstract 1
- BLXXJMDCKKHMKV-UHFFFAOYSA-N Nabumetone Chemical compound C1=C(CCC(C)=O)C=CC2=CC(OC)=CC=C21 BLXXJMDCKKHMKV-UHFFFAOYSA-N 0.000 abstract 1
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 1
- JZFPYUNJRRFVQU-UHFFFAOYSA-N Niflumic acid Chemical compound OC(=O)C1=CC=CN=C1NC1=CC=CC(C(F)(F)F)=C1 JZFPYUNJRRFVQU-UHFFFAOYSA-N 0.000 abstract 1
- TVQZAMVBTVNYLA-UHFFFAOYSA-N Pranoprofen Chemical compound C1=CC=C2CC3=CC(C(C(O)=O)C)=CC=C3OC2=N1 TVQZAMVBTVNYLA-UHFFFAOYSA-N 0.000 abstract 1
- 229960004420 aceclofenac Drugs 0.000 abstract 1
- 229960004892 acemetacin Drugs 0.000 abstract 1
- FSQKKOOTNAMONP-UHFFFAOYSA-N acemetacin Chemical compound CC1=C(CC(=O)OCC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 FSQKKOOTNAMONP-UHFFFAOYSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 229960005142 alclofenac Drugs 0.000 abstract 1
- ARHWPKZXBHOEEE-UHFFFAOYSA-N alclofenac Chemical compound OC(=O)CC1=CC=C(OCC=C)C(Cl)=C1 ARHWPKZXBHOEEE-UHFFFAOYSA-N 0.000 abstract 1
- 229960004663 alminoprofen Drugs 0.000 abstract 1
- FPHLBGOJWPEVME-UHFFFAOYSA-N alminoprofen Chemical compound OC(=O)C(C)C1=CC=C(NCC(C)=C)C=C1 FPHLBGOJWPEVME-UHFFFAOYSA-N 0.000 abstract 1
- 229960003655 bromfenac Drugs 0.000 abstract 1
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N bromfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 ZBPLOVFIXSTCRZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960003184 carprofen Drugs 0.000 abstract 1
- IVUMCTKHWDRRMH-UHFFFAOYSA-N carprofen Chemical compound C1=CC(Cl)=C[C]2C3=CC=C(C(C(O)=O)C)C=C3N=C21 IVUMCTKHWDRRMH-UHFFFAOYSA-N 0.000 abstract 1
- 229960001259 diclofenac Drugs 0.000 abstract 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 abstract 1
- 229960000616 diflunisal Drugs 0.000 abstract 1
- HUPFGZXOMWLGNK-UHFFFAOYSA-N diflunisal Chemical compound C1=C(O)C(C(=O)O)=CC(C=2C(=CC(F)=CC=2)F)=C1 HUPFGZXOMWLGNK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002612 dispersion medium Substances 0.000 abstract 1
- 229960005293 etodolac Drugs 0.000 abstract 1
- XFBVBWWRPKNWHW-UHFFFAOYSA-N etodolac Chemical compound C1COC(CC)(CC(O)=O)C2=N[C]3C(CC)=CC=CC3=C21 XFBVBWWRPKNWHW-UHFFFAOYSA-N 0.000 abstract 1
- 229960001395 fenbufen Drugs 0.000 abstract 1
- ZPAKPRAICRBAOD-UHFFFAOYSA-N fenbufen Chemical compound C1=CC(C(=O)CCC(=O)O)=CC=C1C1=CC=CC=C1 ZPAKPRAICRBAOD-UHFFFAOYSA-N 0.000 abstract 1
- 229950006236 fenclofenac Drugs 0.000 abstract 1
- IDKAXRLETRCXKS-UHFFFAOYSA-N fenclofenac Chemical compound OC(=O)CC1=CC=CC=C1OC1=CC=C(Cl)C=C1Cl IDKAXRLETRCXKS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001419 fenoprofen Drugs 0.000 abstract 1
- 229960002679 fentiazac Drugs 0.000 abstract 1
- 229950007979 flufenisal Drugs 0.000 abstract 1
- 229950001284 fluprofen Drugs 0.000 abstract 1
- 229960002390 flurbiprofen Drugs 0.000 abstract 1
- SYTBZMRGLBWNTM-UHFFFAOYSA-N flurbiprofen Chemical compound FC1=CC(C(C(O)=O)C)=CC=C1C1=CC=CC=C1 SYTBZMRGLBWNTM-UHFFFAOYSA-N 0.000 abstract 1
- 229950009183 ibufenac Drugs 0.000 abstract 1
- CYWFCPPBTWOZSF-UHFFFAOYSA-N ibufenac Chemical compound CC(C)CC1=CC=C(CC(O)=O)C=C1 CYWFCPPBTWOZSF-UHFFFAOYSA-N 0.000 abstract 1
- 229960001680 ibuprofen Drugs 0.000 abstract 1
- 229960000905 indomethacin Drugs 0.000 abstract 1
- 229960004187 indoprofen Drugs 0.000 abstract 1
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 abstract 1
- 229960000991 ketoprofen Drugs 0.000 abstract 1
- 229960002202 lornoxicam Drugs 0.000 abstract 1
- OXROWJKCGCOJDO-JLHYYAGUSA-N lornoxicam Chemical compound O=C1C=2SC(Cl)=CC=2S(=O)(=O)N(C)\C1=C(\O)NC1=CC=CC=N1 OXROWJKCGCOJDO-JLHYYAGUSA-N 0.000 abstract 1
- 229960003803 meclofenamic acid Drugs 0.000 abstract 1
- 229960003464 mefenamic acid Drugs 0.000 abstract 1
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 abstract 1
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 abstract 1
- OJGQFYYLKNCIJD-UHFFFAOYSA-N miroprofen Chemical compound C1=CC(C(C(O)=O)C)=CC=C1C1=CN(C=CC=C2)C2=N1 OJGQFYYLKNCIJD-UHFFFAOYSA-N 0.000 abstract 1
- 229950006616 miroprofen Drugs 0.000 abstract 1
- 229960004270 nabumetone Drugs 0.000 abstract 1
- 229960002009 naproxen Drugs 0.000 abstract 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 abstract 1
- 229960000916 niflumic acid Drugs 0.000 abstract 1
- 229960000965 nimesulide Drugs 0.000 abstract 1
- HYWYRSMBCFDLJT-UHFFFAOYSA-N nimesulide Chemical compound CS(=O)(=O)NC1=CC=C([N+]([O-])=O)C=C1OC1=CC=CC=C1 HYWYRSMBCFDLJT-UHFFFAOYSA-N 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 229960002739 oxaprozin Drugs 0.000 abstract 1
- OFPXSFXSNFPTHF-UHFFFAOYSA-N oxaprozin Chemical compound O1C(CCC(=O)O)=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 OFPXSFXSNFPTHF-UHFFFAOYSA-N 0.000 abstract 1
- 229960002702 piroxicam Drugs 0.000 abstract 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 abstract 1
- 229960000851 pirprofen Drugs 0.000 abstract 1
- PIDSZXPFGCURGN-UHFFFAOYSA-N pirprofen Chemical compound ClC1=CC(C(C(O)=O)C)=CC=C1N1CC=CC1 PIDSZXPFGCURGN-UHFFFAOYSA-N 0.000 abstract 1
- 229960003101 pranoprofen Drugs 0.000 abstract 1
- 150000005599 propionic acid derivatives Chemical class 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 229960000894 sulindac Drugs 0.000 abstract 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 abstract 1
- 229960004492 suprofen Drugs 0.000 abstract 1
- 229960002871 tenoxicam Drugs 0.000 abstract 1
- WZWYJBNHTWCXIM-UHFFFAOYSA-N tenoxicam Chemical compound O=C1C=2SC=CC=2S(=O)(=O)N(C)C1=C(O)NC1=CC=CC=N1 WZWYJBNHTWCXIM-UHFFFAOYSA-N 0.000 abstract 1
- 229960002905 tolfenamic acid Drugs 0.000 abstract 1
- YEZNLOUZAIOMLT-UHFFFAOYSA-N tolfenamic acid Chemical compound CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O YEZNLOUZAIOMLT-UHFFFAOYSA-N 0.000 abstract 1
- 229960001017 tolmetin Drugs 0.000 abstract 1
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 abstract 1
- 229960003414 zomepirac Drugs 0.000 abstract 1
- ZXVNMYWKKDOREA-UHFFFAOYSA-N zomepirac Chemical compound C1=C(CC(O)=O)N(C)C(C(=O)C=2C=CC(Cl)=CC=2)=C1C ZXVNMYWKKDOREA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Suspensión aplicable por vía oral de un principio activo farmacéuticamente del tipo de Fármacos No-Esteroides Anti-Inflamatorios (FNEAI) seleccionado a partir del ácido acetilsalicílico o un FNEAI de las siguientes categorías: a) un derivado de ácido propiónico seleccionado a partir de Ibuprofen, Naproxen, Flurbiprofen, Fenoprofen, Fenbufen, Ketoprofen, Indoprofen, Pirprofen, Carprofen, Oxaprozin, Pranoprofen, Miroprofen, Tioxaprofen, Suprofen, Alminoprofen, ácido tiaprofénico y Fluprofeno a las sales farmacéuticamente aceptables de los mismos, b) un derivado de ácido acético seleccionado a partir de Indomethacin, Sulindac, Tolmetin, Zomepirac, Nabumetone, Diclofenac, Fenclofenac, Alclofenac, Bromfenac, Ibufenac, Aceclofenac, Acemetacin, Fentiazac, Olidanac, Etodolac y Oxpinac, o las sales farmacéuticamente aceptables de los mismos, c) un derivado de ácido fenámico seleccionado a partir de ácido Mefenámico, ácido Meclofenámico, ácido Flupenámico, ácido Niflúmico y ácido Tolfenámico o las sales farmacéuticamente aceptables de los mismos, d) un derivado de ácido bifenilcarboxílico seleccionado a partir de Diflunisal y Flufenisal o las sales farmacéuticamente aceptables de los mismos, e) una enalcarboxamida ácida seleccionada a partir de Piroxicam, Tenoxicam, Lornoxicam y Meloxicam o las sales farmacéuticamente aceptables de los mismos, f) un aril heterociclo con sustituyentes metilsulfonilo o aminosulfonilo o una sal farmacéuticamente aceptable del mismo, y g) una sulfonamida ácida seleccionada a partir de Nimesulide o una sal farmacéuticamente aceptable de la misma, con un espectro de tamaño de grano suspendible en un medio de dispersión fisiológicamente inerte, en el cual el principio activo tiene una solubilidad menor de 500 (g/ml de manera que la suspensión no presenta ningún sabor específico perceptible, ... <EMI FILE="99018550_1" ID="1" IMF=JPEG >
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98105568A EP0945131A1 (de) | 1998-03-27 | 1998-03-27 | Perorale Wirkstoff-Suspension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5070601A1 true CO5070601A1 (es) | 2001-08-28 |
Family
ID=8231651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99018550A CO5070601A1 (es) | 1998-03-27 | 1999-03-26 | Suspencion peroral de meloxicam micronizado que cuenta con bajas proporciones de dioxido de silicio y un polimero hidrofilico como hidroxietilcelulosa, en un medio de dispercion constituido por una solucion reguladora en un rango de ph de 2 a 4 |
Country Status (25)
| Country | Link |
|---|---|
| EP (2) | EP0945131A1 (es) |
| JP (1) | JP3323189B2 (es) |
| KR (1) | KR100587208B1 (es) |
| CN (1) | CN1150888C (es) |
| AR (1) | AR016196A1 (es) |
| AT (1) | ATE225648T1 (es) |
| AU (1) | AU762464B2 (es) |
| BR (1) | BR9909189A (es) |
| CA (1) | CA2326048C (es) |
| CO (1) | CO5070601A1 (es) |
| DE (1) | DE59903023D1 (es) |
| DK (1) | DK1066029T3 (es) |
| ES (1) | ES2184428T3 (es) |
| HU (1) | HU228474B1 (es) |
| IL (1) | IL137479A (es) |
| MY (1) | MY124599A (es) |
| NO (1) | NO321401B1 (es) |
| NZ (1) | NZ507610A (es) |
| PL (1) | PL192969B1 (es) |
| PT (1) | PT1066029E (es) |
| TR (1) | TR200002772T2 (es) |
| TW (1) | TWI232759B (es) |
| UY (1) | UY25443A1 (es) |
| WO (1) | WO1999049845A1 (es) |
| ZA (1) | ZA200003951B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8231899B2 (en) | 1998-09-10 | 2012-07-31 | Nycomed Danmark Aps | Quick release pharmaceutical compositions of drug substances |
| US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
| DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
| US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
| US8512727B2 (en) * | 2003-03-03 | 2013-08-20 | Alkermes Pharma Ireland Limited | Nanoparticulate meloxicam formulations |
| EP1938803A3 (en) * | 2003-03-03 | 2010-10-27 | Elan Pharma International Limited | Formulations comprising nanoparticulate meloxican |
| US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| US20070042006A1 (en) * | 2003-04-07 | 2007-02-22 | Lau Kai K | Stable carprofen composition |
| US20050158367A1 (en) * | 2004-01-16 | 2005-07-21 | The Procter & Gamble Company | Liquid compositions comprising one or more medicaments |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| WO2006042381A1 (en) * | 2004-10-21 | 2006-04-27 | Parnell Laboratories (Aust) Pty Limited | Anti-inflammatory preparation |
| WO2006061351A1 (en) * | 2004-12-06 | 2006-06-15 | Janssen Pharmaceutica N.V. | Oral suspension comprising meloxicam |
| GB2438287A (en) * | 2006-05-19 | 2007-11-21 | Norbrook Lab Ltd | Stable aqueous suspension |
| ES2981178T3 (es) * | 2009-10-12 | 2024-10-07 | Boehringer Ingelheim Vetmedica Gmbh | Recipientes para composiciones que comprenden meloxicam |
| US20110218191A1 (en) * | 2010-03-03 | 2011-09-08 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long term-treatment of kidney disorders in cats |
| BR112012022073A2 (pt) | 2010-03-03 | 2017-10-31 | Boehringer Ingelheim Vetmedica Gmbh | uso de meloxicam para o tratamento de longa duração de distúrbios musculoesqueletais em gatos. |
| WO2011110930A2 (en) * | 2010-03-10 | 2011-09-15 | Lupin Limited | Rifaximin ready-to-use suspension |
| CA2993363A1 (en) * | 2010-03-19 | 2011-09-22 | Boston Biomedical, Inc. | Naphthofuran compounds and compositions for targeting cancer stem cells |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| GB201117858D0 (en) | 2011-10-17 | 2011-11-30 | Norbrook Lab Ltd | Paste |
| JP5908119B2 (ja) * | 2012-12-19 | 2016-04-26 | 三菱電機株式会社 | 空気調和機 |
| RU2749423C2 (ru) | 2015-04-28 | 2021-06-10 | Марс, Инкорпорейтед | Способ получения стерилизованного влажного кормового продукта для домашних животных |
| KR102145022B1 (ko) * | 2018-08-14 | 2020-08-14 | 동아제약 주식회사 | 이부프로펜의 현탁액 조성물 및 투여 제형 |
| CN112044605B (zh) * | 2019-06-06 | 2022-06-21 | 钟志勇 | 选钛药剂及选钛方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1196307B (it) * | 1984-10-22 | 1988-11-16 | Chiesi Farma Spa | Formulazioni farmaceutiche acquose di piroxicam monoidrato |
| US4835187A (en) * | 1987-06-15 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
| JP2860729B2 (ja) * | 1992-03-10 | 1999-02-24 | エスエス製薬株式会社 | プラノプロフェン懸濁シロップ剤 |
| GB2318511A (en) * | 1996-10-23 | 1998-04-29 | Eurand Int | Process for the preparation of a pharmaceutical composition for rapid suspension in water |
-
1998
- 1998-03-27 EP EP98105568A patent/EP0945131A1/de not_active Withdrawn
-
1999
- 1999-03-04 TW TW088103315A patent/TWI232759B/zh not_active IP Right Cessation
- 1999-03-23 PL PL342345A patent/PL192969B1/pl unknown
- 1999-03-23 ES ES99913291T patent/ES2184428T3/es not_active Expired - Lifetime
- 1999-03-23 DK DK99913291T patent/DK1066029T3/da active
- 1999-03-23 DE DE59903023T patent/DE59903023D1/de not_active Expired - Lifetime
- 1999-03-23 HU HU0102036A patent/HU228474B1/hu unknown
- 1999-03-23 AU AU31470/99A patent/AU762464B2/en not_active Expired
- 1999-03-23 NZ NZ507610A patent/NZ507610A/en not_active IP Right Cessation
- 1999-03-23 BR BR9909189-5A patent/BR9909189A/pt not_active Application Discontinuation
- 1999-03-23 EP EP99913291A patent/EP1066029B1/de not_active Expired - Lifetime
- 1999-03-23 AT AT99913291T patent/ATE225648T1/de active
- 1999-03-23 TR TR2000/02772T patent/TR200002772T2/xx unknown
- 1999-03-23 IL IL13747999A patent/IL137479A/xx not_active IP Right Cessation
- 1999-03-23 WO PCT/EP1999/001948 patent/WO1999049845A1/de active IP Right Grant
- 1999-03-23 KR KR1020007010684A patent/KR100587208B1/ko not_active Expired - Lifetime
- 1999-03-23 CN CNB998044695A patent/CN1150888C/zh not_active Expired - Lifetime
- 1999-03-23 CA CA002326048A patent/CA2326048C/en not_active Expired - Lifetime
- 1999-03-23 JP JP2000540811A patent/JP3323189B2/ja not_active Expired - Lifetime
- 1999-03-23 PT PT99913291T patent/PT1066029E/pt unknown
- 1999-03-24 UY UY25443A patent/UY25443A1/es not_active IP Right Cessation
- 1999-03-25 MY MYPI99001139A patent/MY124599A/en unknown
- 1999-03-26 CO CO99018550A patent/CO5070601A1/es unknown
- 1999-03-26 AR ARP990101338A patent/AR016196A1/es not_active Ceased/Invalidation/Refusal/Rejection/Nullification
-
2000
- 2000-08-03 ZA ZA200003951A patent/ZA200003951B/xx unknown
- 2000-09-26 NO NO20004822A patent/NO321401B1/no not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO5070601A1 (es) | Suspencion peroral de meloxicam micronizado que cuenta con bajas proporciones de dioxido de silicio y un polimero hidrofilico como hidroxietilcelulosa, en un medio de dispercion constituido por una solucion reguladora en un rango de ph de 2 a 4 | |
| ES2234324T3 (es) | Combinaciones de un agonista 5ht1b/1d y un inhibidor selectivo de cox-2 para el tratamiento de la migraña. | |
| CA2666036C (en) | Novel compositions and methods for treating hyperproliferative diseases | |
| ES2536200T3 (es) | Preparación de compuestos de tipo 1-(bencilo sustituido)-5-trifluorometil-2-(1H)piridona, sales de estos y sus aplicaciones | |
| AR106237A2 (es) | Inhibidores heterocíclicos de la aspartil proteasa, sus sales farmacéuticamente aceptables | |
| UY29182A1 (es) | "derivados de bencenosulfonamidas sustituídas, composiciones que las contienen, procedimientos de preparación y aplicaciones" | |
| AR051485A1 (es) | Pirazolo pirimidinas 1,4-sustituidas como inhibidores de quinasa | |
| KR100949528B1 (ko) | Ｎｓａｉｄ 및 ｐｄｅ-4 억제제의 조합물 | |
| PA8638101A1 (es) | Inhibidores de cetp | |
| BRPI0606806A2 (pt) | compostos indólicos, suas composições e seus usos | |
| Narsinghani et al. | Lead optimization on conventional non‐steroidal anti‐inflammatory drugs: an approach to reduce gastrointestinal toxicity | |
| DK2207770T3 (da) | 1, 2, 3-triazolderivater til anvendelse som stearoyl-coa desaturase-inhibitorer | |
| IL144127A (en) | Pharmaceutical preparations containing a secondary rich history of carboxylic acid | |
| AU2011222971A1 (en) | Use of meloxicam for the long-term treatment of kidney disorders in cats | |
| NZ582327A (en) | Pharmaceutical combination of nsaid and prostaglandin compound | |
| RU2005103227A (ru) | Новые нестероидные противовоспалительные вещества, составы и способы их применения | |
| Osmaniye et al. | Design, synthesis and biological evaluation of new N‐acyl hydrazones with a methyl sulfonyl moiety as selective COX‐2 inhibitors | |
| US20040198826A1 (en) | Pharmaceutical combination for treating benign prostatic hyperplasia or for treating abacterial prostatitis | |
| AR064865A1 (es) | Derivados de piridina antagonistas de p2y12 | |
| WO2005074930A1 (en) | Pharmaceutical combinations of (s) -pantoprazole with nsaid or corticosteroids | |
| EP1613327A2 (en) | Pharmaceutical combination containing tamsulosin and a non-steroidal anti-inflammatory drug | |
| ES2534506T3 (es) | Uso de inhibidores de porfobilinógeno deaminasa en el tratamiento de la porfiria eritropoyética congénita | |
| EA201401270A1 (ru) | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ (1R,4R)-6'-ФТОР-N,N-ДИМЕТИЛ-4-ФЕНИЛ-4',9'-ДИГИДРО-3'H-СПИРО[ЦИКЛОГЕКСАН-1,1'-ПИРАНО[3,4,b]ИНДОЛ]-4-АМИН И НПРС | |
| DK1165444T3 (da) | Anvendelse af porphyrinderivater i akvarier | |
| CR6503A (es) | Derivados de- 1-trifluorometil-4-hidroxi-7-piperidinil-aminometiclcromano |