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CN111685316A - Nutrient conveying method of short peptide type total nutrient - Google Patents

Nutrient conveying method of short peptide type total nutrient Download PDF

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Publication number
CN111685316A
CN111685316A CN202010464544.9A CN202010464544A CN111685316A CN 111685316 A CN111685316 A CN 111685316A CN 202010464544 A CN202010464544 A CN 202010464544A CN 111685316 A CN111685316 A CN 111685316A
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China
Prior art keywords
nutrient
patient
vitamin
short
intestinal gas
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Pending
Application number
CN202010464544.9A
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Chinese (zh)
Inventor
李高嵩
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Guangzhou Jingteng Medical Technology Co ltd
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Guangzhou Jingteng Medical Technology Co ltd
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Priority to CN202010464544.9A priority Critical patent/CN111685316A/en
Publication of CN111685316A publication Critical patent/CN111685316A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pediatric Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention provides a nutrient conveying method of short peptide type total nutrient. The method of the present invention for delivering nutrients according to microbial community intestinal gas volume allows for more scientific delivery and more efficient absorption of nutrients by monitoring the amount of microbial community intestinal gas associated with a patient, controlling the amount of nutrient delivery to the patient and/or adjusting the rate of nutrient delivery based on the relative change to the microbial community intestinal gas relative to a baseline value. In addition, the short peptide type nutrient is suitable for people who have metabolic gastrointestinal dysfunction such as pancreatitis and the like and critical diseases and are fed before operations of malnutrition patients.

Description

Nutrient conveying method of short peptide type total nutrient
Technical Field
The invention relates to the field of medical treatment, in particular to a nutrition conveying method of short peptide type total nutrient.
Background
For many patients, particularly critically ill patients, it is important to obtain adequate nutrition and begin eating as soon as possible. Proper nutrition can shorten recovery time and increase mortality and morbidity. Medical devices designed to support artificial feeding of patients include various enteral feeding systems. Enteral feeding systems typically provide nutrition to a patient's digestive tract (particularly the stomach, small intestine or jejunum) by inserting a tube under the patient's nose or through the stomach wall. Instead, parental nutrition is provided intravenously, thereby avoiding the usual digestive process. Parenteral nutrition is generally recommended over parenteral nutrition because it is important to use the closest approach to natural feeding to prevent intestinal closure, if possible. Once artificial feeding is initiated, it is important to assess the patient's tolerance to artificial feeding and to determine whether the patient has acquired sufficient nutrition. Many artificially fed patients may be malnourished due to an insufficient amount of nutrients being provided to the patient. This problem is exacerbated where the caregiver slows the rate of feeding to prevent vomiting and diarrhea. Therefore, there is a need for a nutrient delivery method that allows for scientific delivery of nutrients such that the patient receives adequate nutrition. In addition, the existing nutrients are various in variety, and no specific nutrient formula is developed for the pathology of a patient. Specifically, the short peptide is a compound which is generated by hydrolyzing protein and has peptide bonds of 2-10 amino acids, and is a section of active, easily absorbed and high-physiological-function-valence nutrient substance between macromolecular protein and amino acid.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides a nutrient conveying method of short peptide type total nutrient. The technical scheme of the invention is as follows:
a method for transporting a short-peptide type complete nutrient, which comprises the following components: the short peptide type total nutrient comprises the following components per 100 g: 16.0g of protein, 77.0g of carbohydrate, 240mg of sodium, 300 mu g of vitamin A, 4.1 mu g of vitamin D, 4.71mg of vitamin E, 33.7 mu g of vitamin K and vitamin B10.61mg, vitamin B20.61mg, vitamin B61.0mg, vitamin B120.99 mu g, vitamin C45.0 mg, nicotinic acid 3.1mg, folic acid 180 mu g, pantothenic acid 3.0mg, phosphorus 45mg, potassium 445mg, iron 4.0mg, calcium 215mg, zinc 4.1 mg; the nutrient delivery method comprises the following steps:
monitoring the number of intestinal flora of the patient to determine a baseline value of microflora intestinal gas prior to delivering the nutrients to the patient;
monitoring the amount of microflora intestinal gas associated with the patient, controlling the amount of nutrient delivered to the patient and/or adjusting the rate of nutrient delivery based on the relative change to microflora intestinal gas relative to a baseline value;
providing a nutrient to the patient when the microbiota intestinal gas quantity associated with the patient is less than a first threshold, increasing a nutrient delivery rate if the microbiota intestinal gas quantity is less than the first threshold for a duration greater than a first time period; maintaining the nutrient delivery rate substantially constant if the detected amount of microbial population gas is greater than the first threshold value and less than the second threshold value; stopping providing the nutrient to the patient when the microbial intestinal gas quantity associated with the patient is zero, and decreasing the nutrient delivery rate if the detected microbial population intestinal gas quantity is greater than a second threshold value; meanwhile, if the nutrient delivery volume is accumulated to reach a nutrient saturation value in a time interval, the nutrient delivery to the patient is stopped; wherein the first threshold, the second threshold, and the nutrient saturation value are all set based on a baseline value.
Preferably, the source of protein comprises whey protein peptides, the source of carbohydrate comprises maltodextrin, and the protein comprises 35% to 55% of short peptide total nutrients, and wherein the protein is any one of free amino acids, whey protein hydrolysate, casein protein hydrolysate, soy protein hydrolysate, or a combination thereof.
Preferably, the short-peptide type total nutrient contains 1655.0KJ of energy per 100g, and 2.0g of fat, wherein the source of the fat comprises medium-chain triglyceride or long-chain triglyceride; the short peptide type total nutrient comprises 71% of carbohydrate, 15% of protein and 14% of fat.
Preferably, the nutrients are delivered to the patient in a continuous and intermittent manner.
Preferably, the nutrients are delivered by insertion into the stomach, nose, or throat of the patient.
Preferably, monitoring the microflora intestinal gas volume comprises monitoring the concentration of microflora intestinal gas from one selected from the patient's respiratory tract, the patient's digestive tract, or a combination thereof.
Compared with the prior art, the invention has the following beneficial technical effects: the present invention provides a method for delivering nutrients according to microbial community intestinal gas amount by monitoring the amount of microbial community intestinal gas associated with a patient, controlling the amount of nutrient delivery to the patient and/or adjusting the rate of nutrient delivery based on the relative change to the microbial community intestinal gas relative to a baseline value, such that the delivery of nutrients is more scientific and absorption is more efficient. In addition, the short peptide type nutrient has scientific formula and is suitable for people suffering from metabolic gastrointestinal dysfunction such as pancreatitis and critical diseases and feeding patients before operation with malnutrition.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall fall within the protection scope of the present application.
The present example provides a method for nutrient delivery of short-peptide total nutrients, the composition of which comprises per 100g of the short-peptide total nutrients: 16.0g of protein, 77.0g of carbohydrate, 240mg of sodium, 300 mu g of vitamin A, 4.1 mu g of vitamin D, 4.71mg of vitamin E, 33.7 mu g of vitamin K and vitamin B10.61mg, vitamin B20.61mg, vitamin B61.0mg, vitamin B120.99 mu g, vitamin C45.0 mg, nicotinic acid 3.1mg, folic acid 180 mu g, pantothenic acid 3.0mg, phosphorus 45mg, potassium 445mg, iron 4.0mg, calcium 215mg, zinc 4.1 mg; the nutrient delivery method comprises the following steps:
monitoring the number of intestinal flora of the patient to determine a baseline value of microflora intestinal gas prior to delivering the nutrients to the patient;
monitoring the amount of microflora intestinal gas associated with the patient, controlling the amount of nutrient delivered to the patient and/or adjusting the rate of nutrient delivery based on the relative change to microflora intestinal gas relative to a baseline value;
providing a nutrient to the patient when the microbiota intestinal gas quantity associated with the patient is less than a first threshold, increasing a nutrient delivery rate if the microbiota intestinal gas quantity is less than the first threshold for a duration greater than a first time period; maintaining the nutrient delivery rate substantially constant if the detected amount of microbial population gas is greater than the first threshold value and less than the second threshold value; stopping providing the nutrient to the patient when the microbial intestinal gas quantity associated with the patient is zero, and decreasing the nutrient delivery rate if the detected microbial population intestinal gas quantity is greater than a second threshold value; meanwhile, if the nutrient delivery volume is accumulated to reach a nutrient saturation value in a time interval, the nutrient delivery to the patient is stopped; wherein the first threshold, the second threshold, and the nutrient saturation value are all set based on a baseline value. Illustratively, the first threshold is in a range of about 15cfu/g to about 30cfu/g and the second threshold is in a range of about 45cfu/g to about 85 cfu/g.
Optionally, the source of protein comprises whey protein peptides, the source of carbohydrate comprises maltodextrin, the protein comprises 35% to 55% of short peptide total nutrients, and wherein the protein is any one of free amino acids, whey protein hydrolysate, casein protein hydrolysate, soy protein hydrolysate, or a combination thereof.
Optionally, the short-peptide total nutrient contains 1655.0KJ of energy per 100g of the short-peptide total nutrient, and 2.0g of fat, wherein the source of the fat comprises medium-chain triglyceride or long-chain triglyceride; the short peptide type total nutrient comprises 71% of carbohydrate, 15% of protein and 14% of fat.
Alternatively, the nutrients are delivered to the patient in a continuous and intermittent manner.
Alternatively, the nutrients are delivered by insertion into the stomach, nose, or throat of the patient.
Optionally, monitoring the microflora intestinal gas volume comprises monitoring the concentration of microflora intestinal gas from one selected from the patient's respiratory tract, the patient's digestive tract, or a combination thereof.
The above-mentioned embodiments are only specific embodiments of the present application, and are used for illustrating the technical solutions of the present application, but not limiting the same, and the scope of the present application is not limited thereto, and although the present application is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: any person skilled in the art can modify or easily conceive the technical solutions described in the foregoing embodiments or equivalent substitutes for some technical features within the technical scope disclosed in the present application; such modifications, changes or substitutions do not depart from the spirit and scope of the present disclosure, which should be construed in light of the above teachings. Are intended to be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims (5)

1. A method for transporting a short-peptide type total nutrient, wherein the short-peptide type total nutrient has a composition comprising, per 100g of the short-peptide type total nutrient: 16.0g of protein, 77.0g of carbohydrate, 240mg of sodium, 300 mu g of vitamin A, 4.1 mu g of vitamin D, 4.71mg of vitamin E, 33.7 mu g of vitamin K and vitamin B10.61mg, vitamin B20.61mg, vitamin B61.0mg, vitamin B120.99 mu g, vitamin C45.0 mg, nicotinic acid 3.1mg, folic acid 180 mu g, pantothenic acid 3.0mg, phosphorus 45mg, potassium 445mg, iron 4.0mg, calcium 215mg, zinc 4.1 mg; the nutrient delivery method comprises the following steps:
monitoring the number of intestinal flora of the patient to determine a baseline value of microflora intestinal gas prior to delivering the nutrients to the patient; monitoring the microflora intestinal gas volume comprises monitoring the concentration of microflora intestinal gas from one selected from the patient's respiratory tract, the patient's digestive tract, or a combination thereof.
Monitoring the amount of microflora intestinal gas associated with the patient, controlling the amount of nutrient delivered to the patient and/or adjusting the rate of nutrient delivery based on the relative change to microflora intestinal gas relative to a baseline value;
providing a nutrient to the patient when the microbiota intestinal gas quantity associated with the patient is less than a first threshold, increasing a nutrient delivery rate if the microbiota intestinal gas quantity is less than the first threshold for a duration greater than a first time period; maintaining the nutrient delivery rate substantially constant if the detected amount of microbial population gas is greater than the first threshold value and less than the second threshold value; stopping providing the nutrient to the patient when the microbial intestinal gas quantity associated with the patient is zero, and decreasing the nutrient delivery rate if the detected microbial population intestinal gas quantity is greater than a second threshold value; meanwhile, if the nutrient delivery volume is accumulated to reach a nutrient saturation value in a time interval, the nutrient delivery to the patient is stopped; wherein the first threshold, the second threshold, and the nutrient saturation value are all set based on a baseline value.
2. The short peptide complete nutrient of claim 1, wherein the source of protein comprises whey protein peptide, the source of carbohydrate comprises maltodextrin, and the protein comprises 35% to 55% of the short peptide complete nutrient, and wherein the protein is any one of free amino acids, whey protein hydrolysate, casein protein hydrolysate, soy protein hydrolysate, or a combination thereof.
3. The short-peptide complete nutrient of claim 2, wherein the short-peptide complete nutrient has an energy of 1655.0KJ per 100g and a fat content of 2.0g, and the source of the fat comprises medium-chain triglycerides or long-chain triglycerides; the short peptide type total nutrient comprises 71% of carbohydrate, 15% of protein and 14% of fat.
4. The method for the nutritional delivery of short-peptide total nutrients of claim 3 wherein the nutrients are delivered to the patient in a continuous and intermittent manner.
5. The nutrient delivery method of short peptide type total nutrients as claimed in claim 3 or 4, wherein the nutrients are delivered by being inserted into the stomach, nose, throat of the patient.
CN202010464544.9A 2020-05-26 2020-05-26 Nutrient conveying method of short peptide type total nutrient Pending CN111685316A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2537424A1 (en) * 2011-06-22 2012-12-26 Fresenius Kabi Deutschland GmbH High calorie, protein-rich enteral tube feeding
CN103249355A (en) * 2010-12-14 2013-08-14 金伯利-克拉克环球有限公司 Method and system for monitoring nutritional uptake as a function of microflora intestinal gas levels
US20160095339A1 (en) * 2014-10-01 2016-04-07 Mead Johnson Nutrition Company Nutritional composition for gastrointestinal environment to provide improved microbiome and metabolic profile
CN108703376A (en) * 2018-05-25 2018-10-26 上海市浦东医院 A kind of short peptide type many polymerizers of the EA

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103249355A (en) * 2010-12-14 2013-08-14 金伯利-克拉克环球有限公司 Method and system for monitoring nutritional uptake as a function of microflora intestinal gas levels
EP2537424A1 (en) * 2011-06-22 2012-12-26 Fresenius Kabi Deutschland GmbH High calorie, protein-rich enteral tube feeding
US20160095339A1 (en) * 2014-10-01 2016-04-07 Mead Johnson Nutrition Company Nutritional composition for gastrointestinal environment to provide improved microbiome and metabolic profile
CN108703376A (en) * 2018-05-25 2018-10-26 上海市浦东医院 A kind of short peptide type many polymerizers of the EA

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
朱明炜;崔红元;: "肠内营养制剂的合理应用", 临床药物治疗杂志, no. 06 *
花天放: "肠内营养制剂及其应用", 外科理论与实践, no. 04 *
黄琳;吴辰;李玉珍;: "肠内营养制剂的新进展及其安全应用", 中国医院用药评价与分析, no. 05, pages 388 - 389 *

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Application publication date: 20200922

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