CN117177669A

CN117177669A - Pesticidal mixtures

Info

Publication number: CN117177669A
Application number: CN202280029156.5A
Authority: CN
Inventors: P·库尔卡尼; D·开斯特克; E·贝尼蒂; J·乌贝尔; C·B·佩娜贝塔雷洛; C·S·图拉蒂; M·福雷姆林斯基
Original assignee: Makhteshim Chemical Works Ltd
Current assignee: Adama Makhteshim Ltd
Priority date: 2021-04-02
Filing date: 2022-03-31
Publication date: 2023-12-05

Abstract

The present application relates to novel combinations of active compounds comprising a fluoroureide and at least one additional active compound, and methods of controlling pests comprising administering said combinations.

Description

Pesticidal mixtures

The application claims the benefits of the following three indian provisional applications: IN 202131015784 submitted at month 02 of 2021; IN 202131015786 submitted at month 02 of 2021; and IN 202111028811 submitted at month 26 of 2021; the entire contents of which are hereby incorporated by reference.

Throughout this disclosure, various publications are referenced. The disclosures of the documents and publications cited herein are incorporated by reference in their entirety into the present application.

Technical Field

The present application relates to novel combinations of active compounds comprising a fluoroureide (novaluron) and at least one additional active compound, and methods of controlling pests comprising administering said combinations.

Background

Crop plants are vulnerable to pests such that pest control is one of the primary management components in the overall crop production system. Insects are extremely damaging to crop plants and can significantly reduce crop yield and quality. The insecticide helps to minimize this damage by controlling insect pests. Many insecticides and compositions are commercially available for these purposes.

Combinations of insecticides are typically used to expand the control spectrum by adding, minimize the dosage of chemicals used, delay the development of resistance, and reduce the cost of treatment. Although many combinations of insecticides have been studied, little synergy is achieved.

In addition, the activity and selective behavior of any particular mixture is difficult to predict because the behavior of each individual insecticide in a mixture is generally affected by the presence of other components and the activity of the mixture may also vary greatly depending on the chemical characteristics, plant species, stage of growth, and environmental conditions. Typically, this practice results in a reduction of the insecticidal activity in the mixture.

Practical agricultural experience has shown that repeated and specific application of individual active compounds in insect pest control in many cases results in selection of those pests that develop natural or adaptive resistance to the active compound in question. It is then no longer possible to effectively control these pests with the active compound in question.

Another difficulty associated with the use of insecticides is that in many cases repeated and specific application of individual insecticidal compounds results in rapid selection of pests that develop natural or adaptive resistance to the active compound in question. Thus, there is a need for pest control agents that help prevent or overcome resistance. In order to reduce the risk of insect pests developing resistance to certain active compounds, it is common today to use mixtures of different active compounds for controlling the insect pests. By combining active compounds with different mechanisms of action, active control over a relatively long period of time can be ensured.

Insect Growth Regulators (IGRs) are substances that interfere with and/or inhibit the life cycle of insect pests. IGR includes juvenile hormone analogs, ecdysone agonists and chitin synthesis inhibitors. As the insect grows, it will molt, grow a new exoskeleton under its old exoskeleton, and then shed the old exoskeleton, allowing the new exoskeleton to grow to a new size and harden. IGR prevents insects from reaching maturity by interfering with the molting process. This in turn inhibits infestation because immature insects cannot reproduce. Since IGRs act by interfering with the insect's molting process, they take longer to kill than traditional insecticides that have immediate or rapid action knockdown effects.

The active compounds mentioned below are known, for example, from "The Pesticide Manual [ handbook of pesticides ]" published by the british crop protection committee, 11 th edition, 1997. The fluoroureides are described on page 888. The fluoroureide is a benzoylurea having the formula (+) -l- [ 3-chloro-4- (1, 2-trifluoro-2-trifluoromethoxyethoxy) phenyl ] -3- (2, 6-difluorobenzoyl) urea. Known are fluoroureides of the formula

Can be used for controlling animal pests, in particular insects.

The fluoroureides act primarily through ingestion and contact. The fluoroureide disrupts the formation of the dissolved (post-apolic) stratum corneum, resulting in sloughing and subsequent thinning of the stratum corneum. The disruption of this new stratum corneum formation results in ecdysis that fails during the ecdysis process. Fluoroureides are commonly used to control a wide range of pests, including lepidoptera, coleoptera, and diptera. The recommended application rate of the fluoroureide depends on the target pest and ranges from about 1-1000g a.i./ha.

Bishydrazide insecticides are ecdysone agonists that show excellent insecticidal activity by inducing premature ecdysis. These insecticides target lepidoptera but are not harmful to beneficial insects. These compounds mimic the natural insect ecdysone by competing with ecdysteroid receptors in insect cells, thus inducing premature larval ecdysis. Examples of bishydrazide insecticides include chromafenozide, chlorfenozide, methoxyfenozide and tebufenozide.

Pyrethroid insecticides are organic compounds similar to natural pyrethrins, which are produced by flowers of pyrethrum, such as pyrethrum (Chrysanthemum cinerariaefolium) and chamomile (c.coccineum). Pyrethroids are commonly used as commercial and household insecticides, although generally harmless to humans, but toxic to insects such as bees, dragonflies, faheaded flies, and some other invertebrates, mediated primarily by preventing the closing of voltage-gated sodium channels in the axonal membranes of the insects. Pyrethroid insecticides include, but are not limited to, tau-fluvalinate, lambda-cyhalothrin, and bifenthrin.

Spinosad (spinosyn) is a family of broad-spectrum insecticides, including spinosad (spinosad) and spinetoram (spinetoram), all having a macrolide structure, isolated from the actinomycete soil bacteria spinosad (Saccharopolyspora spinosa). Spinosad and spinosad have novel modes of action, primarily targeting binding sites on the nicotinic acetylcholine receptors (nachrs) of the insect nervous system, which sites are distinct from those of other insecticides that have their activity. Spinosad has been used worldwide to control a variety of insect pests including lepidoptera, diptera, thysanoptera, coleoptera, orthoptera and hymenoptera, as well as many other insect pests including thrips.

Methoxypiperidine ethyl and spirotetramat belong to the same chemical class of insecticides (tetramic acid, cyclic ketoenols) that act as inhibitors of acetyl-coa carboxylase (ACC). These insecticides have activity against sucking insects such as aphids, mites and whiteflies by acting as ACC inhibitors, interrupting lipid biosynthesis in the insects.

MetI (mitochondrial Complex I electron transport inhibitor) acaricides and insecticides, such as tolfenpyrad, of the chemical class act by inhibiting cellular respiration in insects, producing excellent knockdown effects. Tolfenpyrad is an ideal rotating chemical, with excellent tank mix partners and with good residual efficacy to control a wide range of pests.

Pyridine organic compounds, such as flonicamid, a chordal organ modulator (Chortodonal Organ Modulator), are used as insecticides against aphids, whiteflies and thrips. Damage to the insect chord tone organ that can affect hearing, balance, movement, to cause cessation of ingestion. The mode of action is different from other insecticides such as neonicotinoid, pymetrozine and praziquantel.

Tone organ TRPV (vanilloid) transient receptor potential) channel modulators, such as pymetrozine, propiconazole and praziquantel, exclusively destroy the feeding of insects that inhale plant sap. Pymetrozine, propiconazole and praziquantel can be directly combined with insect Nanchung (Nan) and Inactive (Iav) proteins.

Aryl isoxazolines, such as fluxazolamide and isoxazole amide, are gamma-aminobutyric acid (GABA) gated chloride channel (gated chloride channel) allosteric modulators that show a high broad spectrum of activity against various lepidopteran, thysanopteran and dipteran pest species. Meta-diamides, such as bromofluorobenzene bisamide, which is also a GABA-gated chloride channel allosteric modulator, have a broad spectrum of activity (crop and non-crop pests) and can be used in different crops to control lepidoptera, coleoptera, termites, ants, cockroaches and flies.

Diamides of the insecticidal class (phthalic diamides and anthranilamides) act as highly specific ranitidine (rynodin) receptor (RyR) modulators. Cyclotrimide and tetrazolium-chlorantraniliprole are structural analogues of anthranilamide, chlorantraniliprole and cyantraniliprole in this class. Tetrazolium carboxamides have good activity against a broad spectrum of insect pests including lepidoptera, coleoptera, leaf miners and selected other diptera and aphids. It can be applied from early season to late season as a foliar and soil treatment. Cyclofenacet is a broad-spectrum insecticide used in leafy vegetables, cucurbits, fruit vegetables and Brassica (Brassica/cole) vegetable crops. In addition to diamide activity, lepidopteran pests are also controlled.

Arylalkoxypyrimidine compounds, such as benzpyrimoxanil, effectively control rice planthoppers and leafhoppers, and have a long lasting effect. By inhibiting the molting of larvae of rice planthoppers and leafhoppers, it reduces the number of insect populations in the rice field. The product has good selectivity and has little effect on non-target organisms such as pollinating insects and natural enemies.

A novel class of mesoionic pyrido [1, 2-alpha ] pyrimidinones, such as dichloropyrimidine (dichloromzotif), have insecticidal activity in controlling many insect species. It is a powerful insecticide to control a wide range of lepidopterans.

Novel quinoline insecticides, such as flubendiamondback carbonate, exhibit good insecticidal activity against plutella xylostella (Plutella xylostella) and armyworm (Mythimna separata). It is a powerful insecticide to control thrips, whiteflies and lepidoptera.

Novel chemical insecticides, such as flubendiamide (fluupyrin), are effective against major insect pests in rice, such as rice planthoppers and stem borers, including those populations that are resistant to existing insecticides. It binds to the acetylcholine site on the nicotinic acetylcholine receptor (nAChR), causing a range of symptoms in insects from hyperexcitability to somnolence and paralysis.

Aryl ethylsulfonyl compounds, such as oxazolesulfonyl, exhibit broad spectrum control of insect pests (including hemiptera, coleopteran, and lepidoptera). Because of its broad insecticidal spectrum, the compound can be grown as a large group of insecticides as a highly versatile pest control agent.

Chlorpyrad is a member of the class of pyrazoles and is an organofluorine compound. Which are insecticidal candidates for feeding on juice. Pyrazole carboxamides insecticides, such as oxazine, having pyridin-3-yl groups are effective against aphids.

Pyrrole compounds, such as chlorfenapyr, are members of the pyrrole class of 4-bromo-1H-pyrrole-3-carbonitrile, which are substituted at positions 1, 2 and 5 with ethoxymethyl, p-chlorophenyl and trifluoromethyl groups, respectively. Chlorfenapyr is commercially used for termite control and crop protection against a wide variety of insect and mite pests.

Sulfoximines (sulfoximines), such as sulfoxaflor, are a class of insecticides that are important and highly effective tools for growers targeting refractory pests such as aphids and lygus lucorum, and are also effective against pests that are resistant to carbamate, neonicotinoid, organophosphate and pyrethroid insecticides.

Furanicotinyl (furanicotinyl) insecticides, such as dinotefuran, represent a third generation group of neonicotinoids. Dinotefuran acts as an agonist of the insect nicotinic acetylcholine receptor and is highly active against a particular strain of bemisia tabaci that develops resistance against imidacloprid.

Organophosphates such as acephate and malathion bind and inhibit the enzyme acetylcholinesterase (AChE) in nervous system tissues and are systemic insecticides used to control sucking and biting insects by direct contact or ingestion on food crops, agricultural seeds and infirm plants, institutional and commercial buildings (including public health facilities), turf, golf course lawns, leech and horticultural nursery plants.

Foliar contact insecticides or acaricides, such as spiromesifen, belonging to the class of ketoenol chemicals, have been used to control mites and whiteflies on vegetables, fruits, cotton and tea. Spiromesifen is active against all stages of development of mites and whiteflies, yielding durable control.

Phenylpyrazole chemical compounds, such as fipronil, are broad spectrum insecticides that are used to control ants, beetles, cockroaches, fleas, ticks, termites, mole cricket, thrips, rootworm, weevil and other insects. Fipronil is a white powder with a moldy smell.

Tetramic acid insecticides, such as dispiro, have a high plant mobility which ensures a high efficacy against key sucking pests (aphids, whiteflies) at low dose rates for foliar and soil applications, suitable for application in cultivated and horticultural crops such as soybeans, cotton, fruit and vegetables.

Phenylpyrazole insecticides, such as tolfenpyrad, are a class of chemically related broad-spectrum insecticides characterized by a central pyrazole ring having a phenyl group attached to one of the pyrazole nitrogen atoms.

Ecdysteroid compounds, such as ecdysone, are steroid pre-hormones of the main insect ecdysone 20-hydroxyecdysone, which are secreted by the thymus gland. Ecdysteroids act as ecdysone for arthropods, but also occur in other related gates (phyla), where they can exert different effects.

WO 2006/048868 discloses the use of a combination of a fluoroureide and an insecticidal compound selected from imidacloprid and acetamiprid with an effective knockdown effect for insect control in crops and their locus.

WO 2007/019962 discloses insecticidal mixtures comprising a fluoroureide and at least one further known active compound from the group of neonicotinoids, and the use of these mixtures for controlling animal pests.

WO 2015/196339 discloses a method of protecting rice from infestation and attack by pests and comprises contacting the rice with a pesticidal composition comprising synergistically effective amounts of spinetoram and methoxyfenozide.

It is an object of the present invention to provide mixtures and compositions which have improved activity against harmful pests when applied in a reduced total amount of active compounds. It is an object of the present invention to provide an expanded activity profile or a combination of knockdown activities with prolonged control. It is another object of the present invention to provide mixtures and compositions that provide effective resistance management and insect pest control at as low application rates as possible.

One effort of the present invention is to find mixtures comprising a fluoroureide and at least one compound from the above mentioned group to be synergistically effective (administered simultaneously (i.e. jointly or separately), or sequentially), allow better control of insect pests (than is possible with single compounds alone), provide synergistic results by reducing dose rates or enhancing activity profiles or combining knockdown activity with prolonged control or promoting resistance management and solve at least one challenge in the prior art.

In light of the foregoing, the present invention has been made in an effort to develop novel insecticidal combinations and compositions that exhibit synergistic enhancement, a broader range of activity and reduced treatment costs.

Disclosure of Invention

We have found that this object is achieved, in whole or in part, by the combinations of the active compounds defined below, as described above.

The invention relates to a pesticidal mixture comprising as active compounds:

i) Compound I which is a fluoroureide of formula (I)

And

II) at least one active compound II selected from the group a.1 to a.26:

A.1. a bishydrazide insecticide which is an ecdysone agonist selected from the group comprising chromafenozide, chlorfenozide, methoxyfenozide and tebufenozide;

A.2. a pyrethroid insecticide selected from the group comprising tau-fluvalinate, lambda-cyhalothrin and bifenthrin;

A.3. a spinosad insecticide selected from the group comprising spinosad and spinetoram;

A.4. tetramic acid, cyclic ketoenols insecticides which are acetyl-coa carboxylase (ACC) inhibitors selected from the group comprising methoxypiperidine ethyl and spirotetramat;

METIs (mitochondrial Complex I electron transport inhibitors) acaricides and insecticides selected from the group comprising tolfenpyrad;

A.6. A pyridine organic compound which is a chordal organ modulator selected from the group comprising flonicamid;

A.7. a chordal organ TRPV (vanilloid transient receptor potential) channel modulator selected from the group comprising pymetrozine, propiconazole and praziquantel;

A.8. aryl isoxazolines which are gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulators selected from the group comprising fluxapyroxad and isoxazole acetamiprid;

A.9. meta-diamides which are GABA-gated chloride channel allosteric modulators selected from the group comprising bromothalonil diamides;

A.10. diamides of the insecticidal class, which are highly specific raniliprole receptor (RyR) modulators selected from the group comprising cycloxaprid and tetrazolium;

A.11. an arylalkoxypyrimidine compound selected from the group comprising saflufenacil;

A.12. a mesoionic pyrido [1,2- α ] pyrimidinone selected from the group comprising dichloropyrimidine;

A.13. novel quinoline insecticides selected from the group comprising fipronil carbonate;

A.14. a novel chemical insecticide selected from the group comprising flubendiamide;

A.15. an aryl ethyl sulfonyl compound selected from the group comprising oxazolesulfonyl worm pyridine;

A.16. An organofluorine compound selected from the group comprising chlorpyrad;

A.17. a pyrazole carboxamide insecticide selected from the group comprising oxaziclomefone;

A.18. a pyrrole compound selected from the group comprising chlorfenapyr;

A.19. a sulfoximine compound selected from the group comprising sulfoxaflor;

A.20. a furanyl nicotinyl compound selected from the group comprising dinotefuran;

A.21. an organic phosphate compound selected from the group consisting of acephate and malathion;

A.22. a foliar contact insecticide selected from the group comprising spiromesifen;

A.23. a phenylpyrazole chemical compound selected from the group comprising fipronil;

A.24. a tetramic acid insecticide selected from the group comprising dispiro;

A.25. a phenylpyrazole insecticide selected from the group comprising tolfenpyrad;

A.26. an ecdysteroid compound selected from the group comprising ecdysone.

Furthermore, it was found in the present invention that the simultaneous (i.e. co-or separate) administration of one active compound I (i.e. a fluoroureide) and one or more active compounds II or the sequential administration of a fluoroureide and one or more active compounds II (as mentioned above) allows for enhanced control of pests compared to the control rates possible with the individual compounds.

The present invention provides insecticidal mixtures in which the weight ratio of the fluoroureide to the active compound(s) II as mentioned above is from 1:100 to 100:1.

The present invention further provides a pesticidal composition comprising a mixture of a fluoroureide and one or more active compounds II as mentioned above, comprising an agriculturally acceptable carrier, and further comprising at least one surfactant, solid diluent, liquid diluent, or combination thereof.

The invention also provides a method for controlling insects, acarines or nematodes comprising contacting an insect, acarine or nematode or their food supply, habitat, breeding grounds or their locus with a pesticidally effective amount of a mixture according to the invention.

The present invention further provides a method of reducing the total amount of insecticidal active compound necessary to control unwanted pests by: a) The fluoroureide is administered at an administration rate of from about 25% to about 75% of the recommended administration rate and b) one or more active compounds II as mentioned above.

The present invention also provides a method for controlling insects comprising contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above or a composition thereof, to thereby control the insects.

The present invention further provides a method for protecting plants from attack or infestation by insects, which comprises contacting a plant, or the soil or water in which the plant is growing, with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above or a composition thereof, to thereby protect the plant from attack or infestation by insects.

The present invention also provides a method for enhancing knockdown activity and/or prolonged control comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above, or a composition thereof, to thereby enhance knockdown activity and/or prolonged control.

The present invention further provides a method for enhancing plant development comprising applying to a plant, the locus of a plant and/or the propagation material of a plant an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above or a composition thereof, to thereby enhance plant development.

Furthermore, the present invention provides a method for regulating plant growth comprising applying to a plant, the locus of a plant and/or the propagation material of a plant an effective amount of a fluoroureide and one or more active compounds II or a composition thereof as mentioned above, in order to thereby regulate plant growth.

Detailed Description

Definition of the definition

Before elaborating on the present subject matter, it may be helpful to provide definitions of certain terms used herein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present subject matter relates.

As used herein, the term "pest" is used to include animal pests and harmful fungi.

As used herein, the term "AI" refers to an active ingredient.

As used herein, the term "control/controlling" is meant to include, but is not limited to, any killing, growth regulation, inhibition or intervention of the normal life cycle of a given pest activity. These terms include, for example, preventing larval development into mature insects, regulating the appearance of pests from eggs, including preventing hatching, degrading egg material, euthanizing, reducing gut motility, inhibiting chitin formation, disrupting mating or sexual flow, and preventing feeding events. The term "control" also includes the ability to regulate or inhibit the growth or proliferation or colony formation of an organism or population of organisms.

As used herein, the term "knockdown activity" or "knockdown treatment" means that one or more insecticides are applied to control insect infestation of a plant or locus prior to and/or after infestation, or prior to and/or after insect damage is indicated, and/or when pest pressure is low/high. Insect stress can be assessed based on conditions associated with insect development, such as population density and certain environmental conditions.

As used herein, the term "prolonged control" means that a prolonged insecticidal activity is obtained for a prolonged period of time after application of one or more insecticides to control insect infestation of a plant or locus, either before and/or after infestation, or before and/or after insect damage is indicated, and/or when insect pressure is low/high. Insect stress can be assessed based on conditions associated with insect development, such as population density and certain environmental conditions.

As used herein, the term "effective" when used in reference to a method for controlling an undesirable pest such as a nematode means that the method provides a good level of control of the undesirable pest without significantly interfering with the normal growth and development of the crop.

As used herein, the term "effective amount" when used in conjunction with an active ingredient refers to an amount of the active ingredient that is sufficient to achieve a good level of control or activity when digested, contacted or sensed therewith.

As used herein, the term "effective amount" when used in conjunction with inactive components, i.e., additives, such as polymers and organic carriers, refers to an amount of additive sufficient to improve the stability of the composition.

As used herein, the term "agriculturally acceptable carrier" means a carrier known and accepted in the art for forming a composition for agricultural or horticultural use.

As used herein, the term "adjuvant" is defined broadly as any substance that is not an active ingredient per se, but that enhances or aims at enhancing the effectiveness of a pesticide with which it is used. Adjuvants may be understood to include, but are not limited to, spreading agents, penetrating agents, compatibilizing agents and drift retardants.

As used herein, the term "agriculturally acceptable inert additive" is defined as any substance that is not an active ingredient per se but is added to the composition, such as thickeners, binders, surfactants, antioxidants, defoamers, and thickeners.

As used herein, the term "tank mix" means that two or more chemical pesticides or compositions are mixed in a spray tank at the time of spray application.

As used herein, the term "premix" means a composition that can be applied directly to plants after dilution. The composition comprises a combination of active ingredients.

As used herein, the term "plant" includes reference to whole plants, plant organs (e.g., leaves, stems, shoots, roots, stems (trunk), shoots (limb), shoots (shoot), fruits, etc.), and propagation material or plant cells.

As used herein, the term "plant" includes reference to crops, including field crops, vegetable crops, fruit, semi-perennial crops and perennial crops.

As used herein, the term "propagation material" is understood to mean all reproductive parts of a plant, such as seeds and spores; nutritional structures such as bulbs, corms, tubers, underground stems (rhizomes), rhizomes (roots stem), basal shoots (basal shoots), stolon (stolon) and buds.

As used herein, the term "locus" includes habitat, breeding area, plant, breeding material, soil, territory, material or environment where pests are growing or may grow.

As used herein, the term "ha" refers to hectare.

As used herein, the term "g" refers to grams, and "L" or "L" refers to liters.

As used herein, the term "mixture" or "combination" refers to, but is not limited to, a combination in any physical form, such as a blend, solution, suspension, dispersion, emulsion, alloy, and the like.

As used herein, the term "more effective" includes, but is not limited to, increasing the efficacy of the pesticide disease control, extending the protection and reducing the amount of time required to reach a given pesticide control level, extending the duration of protection against pest attack after application and extending the period of protection against pest attack and/or reducing the amount of time required to reach a pest control level, as compared to when the same amount of each pesticide is applied alone.

As used herein, the term "cultivated plant" includes plants that have been modified by breeding, mutagenesis or genetic engineering. Genetically modified plants are plants whose genetic material has been modified by the use of recombinant DNA techniques. Typically, one or more genes have been integrated into the genetic material of such plants in order to improve certain characteristics of the plants.

As used herein, the term "enhancing a crop plant" means improving one or more of the following of a plant to which a mixture or composition described herein has been applied, as compared to a control plant grown under the same conditions except that the mixture or composition described herein has not been applied: plant quality, plant vigor, nutrient uptake, root system, tolerance to stress factors, and/or yield.

As used herein, the term "enhancing a root system" means that the root system of a plant to which a mixture or composition described herein has been applied is qualitatively or quantitatively improved as compared to the root system of a control plant grown under the same conditions except that the mixture or composition described herein has not been applied. Enhanced root systems include, but are not limited to, improved visual appearance and composition of the root system (i.e., improved color, density, and uniformity), increased root growth, a more developed root system, stronger and healthier roots, improved plant density, and increased root weight.

As used herein, the term "improving plant quality" means that one or more traits of a plant to which a mixture or composition described herein has been applied are qualitatively or quantitatively improved as compared to the same traits of a control plant grown under the same conditions except that the mixture or composition described herein has not been applied. Such traits include, but are not limited to, improved visual appearance and composition of the plant (i.e., improved color, density, uniformity, compactness), reduced ethylene (reduced production and/or accepted inhibition), improved visual appearance and composition of the harvested material (i.e., seeds, fruits, leaves, vegetables, shoots/stems/shoots (canes)), improved carbohydrate content (i.e., increased amount of sugar and/or starch, improved sugar acid ratio, reduced reducing sugar, increased sugar formation rate), improved protein content, improved oil content and composition, improved nutritional value, reduced anti-nutritional compounds, increased nutrient absorption, stronger and healthier roots, improved organoleptic properties (i.e., improved taste), improved consumer health benefits (i.e., increased vitamin and antioxidant levels), improved post-harvest characteristics (i.e., increased shelf life and/or enhanced storage stability, easier processing, easier extraction of compounds), and/or improved seed quality (i.e., for subsequent use).

As used herein, the term "plant growth regulation" or "regulating plant growth" includes limiting vertical stem growth, promoting root growth, stunting, increasing stem diameter and stem wall thickness, and the like.

As used herein, the term "plant" refers to all tangible parts of a plant, including but not limited to seeds, seedlings, saplings, roots, tubers, stems, stalks, leaves, and fruits.

As used herein, the term "surfactant" means an agriculturally acceptable material that imparts emulsifying, stabilizing, spreadability, wetting, dispersing, or other surface modifying properties. Examples of suitable surfactants include nonionic, anionic, cationic and amphoteric surfactants.

The term "a/an" as used herein includes both the singular and the plural, unless specifically stated otherwise. Thus, the terms "a/an" or "at least one" are used interchangeably herein.

Throughout this application, the description of the various embodiments uses the term "include"; however, those skilled in the art will appreciate that in some particular cases, the language "consisting essentially of … …" or "consisting of … …" may alternatively be used to describe the embodiments.

For a better understanding of the present teachings and in no way limiting the scope of these teachings, unless indicated to the contrary, the numerical parameters set forth in the following specification and attached claims are approximations that may vary depending upon the desired properties sought to be obtained. At the very least, each numerical parameter should at least be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. In this regard, the use of the term "about" herein specifically includes + -10% of the indicated values within that range. In addition, endpoints of all ranges herein directed to the same component or property are inclusive of the endpoints, independently combinable, and inclusive of all intermediate points and ranges.

Unless otherwise indicated, references to percentages are weight (wt.) percentages of active compounds in the compositions of the present invention based on the total weight of active ingredients in the composition (i.e., the active compounds themselves), excluding any amounts of solvents, carriers, dispersants, stabilizers, or other materials that may be present.

It should be further appreciated that where a range of parameters is provided, the present subject matter also provides all integers and ten equivalents thereof within the range. For example, "0.1% to 50%" includes 0.1%, 0.2%, 0.3%, 0.4%, etc. up to 50%.

When the ratio herein is "X:1 or higher", it means that the ratio is Y:1, wherein Y is X or greater, and when the ratio herein is "X:1 or lower", it means that the ratio is Z:1, wherein Z is X or less. The same logic is followed for ratios of "1:X or higher" and "1:X or lower".

Pesticidal mixtures

It has been unexpectedly found that by combining insecticides, an insecticidal mixture is produced which exhibits a broad control spectrum and high efficacy against an extremely wide range of insects, as well as knockdown and long residual action under different climatic conditions. The mixtures and compositions of the present invention are based in part on the following findings: application of the novel insecticidal mixtures of the present invention to a locus or area where pest control is desired results in improved control of pests and prevention of further infestation.

In some embodiments, the combination provides higher insecticidal activity than would be envisaged based on the sum of the activity of each insecticide seen therein. This combination allows for a reduced dosage of individual insecticides that may damage agriculturally important plants.

In an embodiment, the present invention relates to a pesticidal mixture comprising as active compounds:

i) Compound I, which is a fluoroureide, and

II) at least one active compound II selected from the group a.1 to a.26:

A.16. an organofluorine compound selected from the group comprising chlorpyrad;

A.18. a pyrrole compound selected from the group comprising chlorfenapyr;

A.19. a sulfoximine compound selected from the group comprising sulfoxaflor;

A.24. a tetramic acid insecticide selected from the group comprising dispiro;

A.26. an ecdysteroid compound selected from the group comprising ecdysone.

For use in the pesticidal mixtures of the present invention, the active compound II is selected from the group a.1, a.2, a.3, a.4, a.5, a.6, a.7, a.8, a.9, a.10, a.11, a.12, a.13, a.14, a.15, a.16, a.17, a.18, a.19, a.20, a.21, a.22, a.23, a.24, a.25 and a.26, preferably from the groups a.1, a.3, a.4, a.7, a.8, a.9, a.10, a.12, a.14, a.16, a.18, a.19, a.20, a.21, a.22, a.23 and a.25.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.1 as defined above is preferably chromafenozide, chlorfenozide, methoxyfenozide and tebufenozide, and more preferably methoxyfenozide.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.2 as defined above is preferably tau-fluvalinate.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.3 as defined above is more preferably spinosad or spinetoram.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.4 as defined above is preferably methoxypiperidine ethyl or spirotetramat.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.4 as defined above is more preferably spirotetramat.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.5 as defined above is preferably tolfenpyrad.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.6 as defined above is preferably flonicamid.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.7 as defined above is preferably pymetrozine or hydroprene.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.7 as defined above is more preferably hydroprene.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.8 as defined above is preferably fluxapyroxad or isoxazole tebufenozide.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.8 as defined above is more preferably isoxazole tebufenozide.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.9 as defined above is more preferably bromofluorobenzene bisamide.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.10 as defined above is preferably cycloxaprid or tetrazolium-amide.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.10 as defined above is more preferably tetrazolium carboxamides.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.11 as defined above is preferably saflufenacil.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.12 as defined above is more preferably dichloropyrimidine.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.13 as defined above is preferably flubendiamide.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.14 as defined above is more preferably flubendiamide.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.15 as defined above is preferably oxazolesulfonyl-chloridil.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.16 as defined above is more preferably chlorpyrad.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.17 as defined above is preferably metaxazolamide.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.18 as defined above is more preferably chlorfenapyr.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.19 as defined above is more preferably sulfoxaflor.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.20 as defined above is more preferably dinotefuran.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.21 as defined above is more preferably acephate or malathion.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.22 as defined above is more preferably spiromesifen.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.23 as defined above is more preferably fipronil.

With regard to the pesticidal mixtures of the present invention, the active compound II selected from group a.24 as defined above is preferably a dispiro.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.25 as defined above is more preferably tolfenpyrad.

With respect to the pesticidal mixtures of the present invention, the active compound II selected from group a.26 as defined above is preferably ecdysone.

In one embodiment, the insecticidal mixture allows for enhanced control of pests compared to the control rates possible with a single active compound, wherein the mixture is prepared by simultaneous (i.e., co-or separate) administration of the fluoroureide and one or more active compounds II or sequential administration of the fluoroureide and one or more active compounds II (as mentioned above).

In another embodiment, the present invention provides insecticidal mixtures in which the weight ratio of the fluoroureide to the active compound(s) II as mentioned above is from 1:100 to 100:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the bishydrazide insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to methoxyfenozide is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to methoxyfenozide is from 1:1 to 100:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the spinosad insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to spinosad is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to spinosad is from 1:1 to 1:100.

In another embodiment, the invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the spinetoram is from 1:100 to 100:1.

In another embodiment, the invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the spinetoram is from 1:5 to 5:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to spirotetramat is from 1:100 to 100:1.

In a specific embodiment, the invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to the spirotetramat is from 1:1 to 1:100.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the chord organ TRPV (vanilloid transient receptor potential) channel modulator insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to hydroprene is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the novaluron to the hydroprene is from 1:5 to 5:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the arylisoxazoline, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to isoxaflutole is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to isoxaflutole is 1:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to the bromoxynil is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to the bromoxynil is from 1:1 to 10:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the specific ranitidine receptor (RyR) modulator insecticide is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of the novaluron to the tebufenozide is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of the novaluron to the tebufenozide is from 1:5 to 25:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the mesoionic pyrido [1,2- α ] pyrimidinone insecticide is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to the pyrithione is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the pyrithione is 1:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the chemical insecticide is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to fluazinam is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of novaluron to fluazinam is 1:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the organofluorine compound is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to chlorfenapyr is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of novaluron to chlorfenapyr is 1:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the pyrrole compound is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of the novaluron to the chlorfenapyr is from 1:100 to 100:1.

In a specific embodiment, the present invention provides insecticidal mixtures wherein the weight ratio of the novaluron to the chlorfenapyr is from 1:10 to 50:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the sulfoximine compound is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of novaluron to sulfoxaflor is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the novaluron to the sulfoxaflor is from 1:5 to 100:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the fumonioyl compound is from 1:100 to 100:1.

In further embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of the novaluron to dinotefuran is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the novaluron to dinotefuran is 1:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the organophosphate compound is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to acephate is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to acephate is from 1:10 to 10:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to malathion is from 1:100 to 100:1.

In a specific embodiment, the invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to the acephate is 1:10.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of novaluron to malathion is from 1:1 to 1:10.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the foliar contact insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to spiromesifen is from 1:100 to 100:1.

In a specific embodiment, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to spiromesifen is from 1:5 to 100:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is from 1:100 to 100:1.

In further specific embodiments, the present invention provides insecticidal mixtures wherein the weight ratio of the fluoroureide to fipronil is from 1:100 to 100:1.

In an embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the fluoroureide to the phenylpyrazole insecticide is from 1:100 to 100:1.

In further embodiments, the invention provides insecticidal mixtures wherein the weight ratio of novaluron to tolfenpyrad is from 1:100 to 100:1.

In a specific embodiment, the present invention provides an insecticidal mixture wherein the weight ratio of the novaluron to the tolfenpyrad is 1:1.

In another embodiment, the present invention further provides a pesticidal composition comprising a mixture of a fluoroureide and one or more active compounds II as mentioned above, comprising an agriculturally acceptable carrier, and further comprising at least one surfactant, solid diluent, liquid diluent, or combination thereof.

In a further embodiment, the invention also provides a method for controlling insects, acarids or nematodes comprising contacting an insect, acarid or nematode or their food supply, habitat, breeding grounds or their locus with a pesticidally effective amount of a mixture according to the invention.

In an embodiment, the present invention further provides a method of reducing the total amount of insecticidal active compound necessary to control unwanted pests by: a) The fluoroureide is administered at an administration rate of from about 25% to about 75% of the recommended administration rate and b) one or more active compounds II as mentioned above.

In a further embodiment, the invention also provides a method for controlling insects, comprising contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above or a composition thereof, to thereby control insects.

In an embodiment, the present invention further provides a method for protecting plants from attack or infestation by insects, which comprises contacting a plant, or the soil or water in which the plant is growing, with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above, or a composition thereof, to thereby protect the plant from attack or infestation by insects.

In another embodiment, the present invention also provides a method for enhancing knockdown activity and/or prolonged control comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above, or a composition thereof, to thereby enhance knockdown activity and/or prolonged control.

In one of these embodiments, the present invention further provides a method for enhancing plant development comprising applying to a plant, the locus of a plant and/or the propagation material of a plant an effective amount of a mixture of a fluoroureide and one or more active compounds II as mentioned above or a composition thereof, to thereby enhance plant development.

In a further embodiment, the present invention provides a method for regulating plant growth comprising applying to a plant, the locus of a plant and/or the propagation material of a plant an effective amount of a fluoroureide and one or more active compounds II or a composition thereof as mentioned above, to thereby regulate plant growth.

In another embodiment, the present invention provides a composition comprising an effective amount of a fluoroureide and one or more active compounds II as mentioned above, wherein the effective amounts of the two active compounds are selected in such a way that their mixtures produce synergistic insecticidal activity.

In representative examples, enhanced synergistic insecticidal activity was observed when insecticidal mixtures of fluoroureides and bishydrazide insecticides were used to control insects.

In another representative embodiment, the present subject matter relates to an insecticidal mixture comprising a fluoroureide and a bishydrazide insecticide.

In embodiments, the bishydrazide insecticide is chromafenozide, chlorfenozide, methoxyfenozide, tebufenozide, or a combination comprising at least one of the foregoing. In one representative embodiment, the bishydrazide compound is methoxyfenozide.

In one representative embodiment, the present subject matter also provides a pesticidal mixture comprising: (i) an amount of a fluoroureide; and (ii) an amount of methoxyfenozide.

In some embodiments, the amount of the fluoroureide and the amount of the bishydrazide insecticide, if applied together, is more effective than when the same amount of the fluoroureide and the same amount of the bishydrazide insecticide are applied alone.

In some embodiments, the amount of the fluoroureide and the amount of the methoxyfenozide, if administered together, is more effective than when the same amount of the fluoroureide and the same amount of methoxyfenozide are administered alone.

In some embodiments, the amount of the applied fluoroureide is less than an insecticidally effective amount of the fluoroureide (if the fluoroureide is used alone).

In representative embodiments, the amount of dihydrazide insecticide applied is less than the pesticidally effective amount of dihydrazide insecticide (if dihydrazide insecticide is used alone). In particular, in some embodiments, the amount of methoxyfenozide administered is less than an insecticidally effective amount of methoxyfenozide (if methoxyfenozide is used alone).

In some embodiments, the mixture is more effective than if the same amount of the fluoroureide and the same amount of the bishydrazide insecticide were applied alone.

In some embodiments, the mixture is more effective than if the same amount of the novaluron and the same amount of methoxyfenozide insecticide were applied alone.

In some embodiments, the inventive subject matter also provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of a bishydrazide insecticide, wherein the mixture is more effective than the same amount of (i) and/or (ii) applied alone.

In some embodiments, the inventive subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of methoxyfenozide, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of spinosad, wherein the mixture is more effective than administering the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of spinetoram, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of spirotetramat, wherein the mixture is more effective than administering the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of hydroprene, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of isoxaflutole, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of bromothalonil diamide, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of tolfenpyrad, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of pyrithione, wherein the mixture is more effective than administration of the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of flubendiamide, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of chlorpyrad, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of chlorfenapyr, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of sulfoxaflor, wherein the mixture is more effective than administering the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of dinotefuran, wherein the mixture is more effective than administering the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of acephate, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of malathion, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of spiromesifen, wherein the mixture is more effective than administering the same amount of (i) and/or (ii) alone.

In an embodiment, the present subject matter provides a pesticidal mixture comprising: (i) a fluoroureide; and (ii) an amount of fipronil, wherein the mixture is more effective than the same amount of (i) and/or (ii) administered alone.

In some embodiments, the mixture exhibits a synergistic effect.

In some embodiments, the mixture is a synergistic mixture.

In one embodiment, the inventive subject matter relates to a synergistic pesticidal mixture comprising: (i) a fluoroureide; and (II) at least one active compound II selected from the group a.1, a.3, a.4, a.7, a.8, a.9, a.10, a.12, a.14, a.16, a.18, a.19, a.20, a.21, a.22, a.23 and a.25 as defined above.

In representative embodiments, the present subject matter relates to a synergistic pesticidal mixture comprising: (i) a fluoroureide; and (ii) a bishydrazide insecticide.

In further representative embodiments, the present subject matter relates to a synergistic pesticidal mixture comprising: (i) a fluoroureide; and (ii) methoxyfenozide.

In some embodiments, the ratio of (i) an amount of the fluoroureide to (ii) an amount of the bishydrazide insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of methoxyfenozide from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of methoxyfenozide from 1:1 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide to (ii) an amount of the spinosad insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spinosad from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spinosad from 1:1 to 1:100, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spinetoram from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the acetyl-coa carboxylase (ACC) inhibitor insecticide, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spirotetramat from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spirotetramat from 1:1 to 1:100, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of from 1:100 to 100:1 of (i) an amount of a fluoroureide and (ii) an amount of a chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of triclopyr from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of triclopyr from 1:5 to 5:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of from 1:100 to 100:1 of (i) an amount of a fluoroureide and (ii) an amount of an arylisoxazoline that is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of isoxaflutole from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amount of (i) and the same amount of (ii) were applied alone.

In some embodiments, a ratio of 1:1 of (i) an amount of the fluoroureide and (ii) an amount of the isoxazole tebufenozide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amount of (i) and the same amount of (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of bromofluorobenzamide from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron to (ii) an amount of brofenfluramine from 1:1 to 10:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the specific ranitidine receptor (RyR) modulator insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amount of (i) and the same amount of (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of specific tetrazolium amide from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of specific tetrazolium amide from 1:5 to 25:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the mesoionic pyrido [1,2- α ] pyrimidinone insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of dithiazol from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of 1:1 of (i) an amount of the fluoroureide and (ii) an amount of the pyrithione, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the chemical insecticide, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of flubendiamide from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of 1:1 of (i) an amount of novaluron and (ii) an amount of flubendiamide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the organofluorine compound, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of chlorfenapyr from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of 1:1 of (i) an amount of novaluron and (ii) an amount of chlorfenapyr, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the pyrrole compound, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of chlorfenapyr from 1:10 to 50:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the sulfoximine compound from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of sulfoxaflor from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of sulfoxaflor from 1:5 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the fumonic compound, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of dinotefuran from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a 1:1 ratio of (i) an amount of novaluron and (ii) an amount of dinotefuran, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide and (ii) an amount of the organophosphate compound, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of acephate from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of 1:10 of (i) an amount of novaluron and (ii) an amount of acephate, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of malathion from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of malathion from 1:1 to 1:10, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide to (ii) an amount of the foliar contact insecticide, if applied together, is more effective in treating plants or soil against insect infestation than if the same amount of (i) and the same amount of (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spiromesifen, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of spiromesifen, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:5 to 100:1.

In some embodiments, the ratio of (i) an amount of a fluoroureide and (ii) an amount of a phenylpyrazole chemical compound, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of fipronil from 1:100 to 100:1, if applied together, is more effective in treating plants or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, the ratio of (i) an amount of the fluoroureide to (ii) an amount of the phenylpyrazole insecticide, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amount of (i) and the same amount of (ii) were applied alone, from 1:100 to 100:1.

In some embodiments, the ratio of (i) an amount of novaluron and (ii) an amount of tolfenpyrad from 1:100 to 100:1, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In some embodiments, a ratio of 1:1 of (i) an amount of novaluron and (ii) an amount of tolfenpyrad, if applied together, is more effective in treating a plant or soil against insect infestation than if the same amounts of (i) and (ii) were applied alone.

In further embodiments, the pesticidal mixtures of the present invention comprise: (i) a fluoroureide; and (II) at least one active compound II as defined above, having a synergistic effect in controlling pests after a few hours to a few days of administration compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) methoxyfenozide, after 72 hours of administration, is synergistically effective to control pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) methoxyfenozide, after 4 days of administration, has a synergistic effectiveness in controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) methoxyfenozide, after 8 days of administration, has a synergistic effectiveness in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinosad, after 48 hours of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinosad, after 72 hours of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinosad, after 7 days of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinetoram, after 48 hours of administration, is synergistically effective to control pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinetoram, after 72 hours of administration, is synergistically effective to control pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinetoram, after 120 hours of administration, is synergistically effective to control pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spinetoram, which is synergistically effective for controlling pests after 7 days of administration, as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spirotetramat, after 48 hours of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spirotetramat, after 72 hours of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spirotetramat, after 7 days of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) the hydroprene, after 72 hours of administration, has a synergistic effectiveness in controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) isoxazole tolfenpyrad, having a synergistic effect in controlling pests after 72 hours of administration compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) the bromofluorobenzene bisamide has a synergistic effect in controlling pests after 120 hours of administration as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) tetrazolium worm amide, after 72 hours of administration, has a synergistic effectiveness in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) tetrazolium worm amide, after 120 hours of administration, has a synergistic effectiveness in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) dichloropyrimidine, after 72 hours of administration, has a synergistic effect in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) flubendiamide, after 72 hours of administration, has a synergistic effect in controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) the aminopyrazole, after 72 hours of administration, has a synergistic effect in controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) chlorfenapyr, after 48 hours of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) chlorfenapyr, after 72 hours of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) chlorfenapyr, after 7 days of administration, has a synergistic effect on controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) sulfoxaflor, after 48 hours of administration, is synergistically effective in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) sulfoxaflor, has a synergistic effect in controlling pests after 72 hours of administration compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) dinotefuran, after 72 hours of administration, is synergistically effective for controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) acephate, after 72 hours of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) acephate, after 7 days of administration, has a synergistic effect on pest control compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) malathion, having a synergistic effect in controlling pests after 72 hours of administration as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) malathion, having a synergistic effect in controlling pests after 96 hours of administration as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spiromesifen, after 96 hours of administration, is synergistically effective in controlling pests as compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) spiromesifen, after 7 days of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) fipronil, after 72 hours of administration, is synergistically effective for controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) fipronil, after 144 hours of administration, has a synergistic effect on controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) fipronil, after 7 days of administration, has a synergistic effect on controlling pests compared to when at least one component of the mixture is administered alone in the same amount.

In an embodiment, the pesticidal mixture of the present invention comprises: (i) a fluoroureide; and (ii) tolfenpyrad, having a synergistic effect in controlling pests after 72 hours of administration compared to when at least one component of the mixture is administered alone in the same amount.

In some embodiments, the mixture reduces the amount of time required to achieve a level of pest control compared to when at least one component of the same amount of the mixture is applied alone. An example of a reduction is that if the fluoroureide is applied alone, up to 50% insecticidal control 7 days after application, the mixture or combination disclosed herein achieves 50% insecticidal control 2 days after application, with each insecticide applied in an amount.

In some embodiments, the amount of time is reduced by at least 1 day, 2 days, 3 days, 4 days, 5 days, 7 days, 10 days, 14 days, or 21 days, or 28 days.

In some embodiments, the mixture is effective for increasing plant development compared to when at least one component of the same amount of the mixture is administered alone. Increasing plant development includes, but is not limited to, enhancing root systems, enhancing shoots of crop plants, enhancing plant vigor, and/or enhancing potential yield of plants.

In some embodiments, effectiveness is measured as plant vigor, an increase in plant yield, an enhancement of the root system, and/or an enhancement of the shoots.

In some embodiments, plant vigor is assessed using a relative vigor index. In some embodiments, plant vigor is increased by at least 1%, 5%, 10%, 20%, 30%, 40% or 50%.

In some embodiments, enhancement of the root system is measured by root weight. In some embodiments, root weight is increased by at least 1%, 5%, 10%, 20%, 30%, 40%, or 50%.

In some embodiments, the enhancement of the shoot is measured by shoot weight. In some embodiments, the weight of the shoot is increased by at least 1%, 5%, 10%, 20%, 30%, 40% or 50%.

The weight ratio between the fluoroureide and one of the active compounds II as defined above in the composition can generally not be defined, since it varies according to various conditions such as the type of formulation, weather conditions, crop type and pest type.

In one embodiment, the weight ratio of the fluoroureide to bishydrazide insecticide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to bishydrazide insecticide is from about 1:1 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the bishydrazide insecticide is 1:1. In another embodiment, the weight ratio of the fluoroureide to the bishydrazide insecticide is 100:1. The weight ratio of the fluoroureide to bishydrazide insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the methoxyfenozide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to methoxyfenozide insecticide is from about 1:1 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the methoxyfenozide insecticide is 1:1. In another embodiment, the weight ratio of the novaluron to methoxyfenozide insecticide is 100:1. The weight ratio of the novaluron to the methoxyfenozide insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the spinosad insecticide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is from about 1:1 to 100:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is from about 1:100 to 1:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is from about 1:5 to 1:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is from about 5:1 to 1:1. In a specific embodiment, the weight ratio of the fluoroureide to the spinosad insecticide is 1:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is 100:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is 5:1. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is 1:100. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is 1:5. In another embodiment, the weight ratio of the novaluron to the spinosad insecticide is 1:2.5. The weight ratio of the fluoroureide to the spinosad insecticide may be selected from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to spinosad in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to spinosad insecticide is from about 1:100 to 1:1. In a specific embodiment, the weight ratio of the fluoroureide to spinosad is 1:1. In another embodiment, the weight ratio of the novaluron to spinosad is 1:100. The weight ratio of the fluoroureide to spinosad may be selected from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to spinetoram in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is from about 1:1 to 100:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is from about 1:100 to 1:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is from about 1:5 to 1:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is from about 5:1 to 1:1. In a specific embodiment, the weight ratio of the fluoroureide to the spinetoram is 1:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is 100:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is 5:1. In another embodiment, the weight ratio of the novaluron to the spinetoram is 1:100. In another embodiment, the weight ratio of the novaluron to the spinetoram is 1:5. In another embodiment, the weight ratio of the novaluron to the spinetoram is 1:2.5. The weight ratio of the fluoroureide to the spinetoram may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide is from about 1:1 to 1:100. In a specific embodiment, the weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide is 1:1. In another specific embodiment, the weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide is 1:100. The weight ratio of the fluoroureide to the acetyl-coa carboxylase (ACC) inhibitor insecticide may be a mid-range selected from the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the spirotetramat in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to spirotetramat is from about 1:1 to 1:100. In a specific embodiment, the weight ratio of the fluoroureide to the spirotetramat is 1:1. In another embodiment, the weight ratio of the novaluron to the spirotetramat is 1:100. The weight ratio of the fluoroureide to the spirotetramat may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide is from about 1:5 to 5:1. In a specific embodiment, the weight ratio of the fluoroureide to the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide is 1:5. In another embodiment, the weight ratio of the fluoroureide to the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide is 5:1. The weight ratio of the fluoroureide to the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the hydroprene in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the hydroprene is from about 1:5 to 5:1. In a specific embodiment, the weight ratio of the novaluron to the hydroprene is 1:5. In another embodiment, the weight ratio of the novaluron to the hydroprene is 5:1. The weight ratio of the novaluron to the hydroprene may be chosen from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the aryl isoxazoline, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the aryl isoxazoline, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, is 1:1. The weight ratio of the fluoroureide to the aryl isoxazoline, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, may be a mid range selected from the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the isoxazole tebufenozide in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the isoxazole tebufenozide is 1:1. The weight ratio of the novaluron to the isoxaflutole may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) is from about 1:1 to 10:1. In a specific embodiment, the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) is 1:1. In another embodiment, the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) is 2.5:1. In another embodiment, the weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) is 10:1. The weight ratio of the fluoroureide to the meta-diamide (which is a GABA-gated chloride channel allosteric modulator insecticide) may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the bromofluorobenzene bisamide in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the bromofluorobenzene bisamide is from about 1:1 to 10:1. In a specific embodiment, the weight ratio of the novaluron to the brofenfluramine is 1:1. In another specific embodiment, the weight ratio of the novaluron to the bromofluorobenzene bisamide is 2.5:1. In another embodiment, the weight ratio of the novaluron to the bromofluorobenzene bisamide is 10:1. The weight ratio of the fluoroureide to the bromofluorobenzene bisamide can be in a mid-range selected from the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the diamide in the composition, which is a highly specific raniliprole receptor (RyR) modulator insecticide, is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is from about 1:25 to 25:1. In a specific embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is 1:1. In another specific embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is 2.5:1. In another specific embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is 25:1. In another specific embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is 5:1. In another specific embodiment, the weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is 1:5. The weight ratio of the fluoroureide to the diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the tolfenpyrad in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the tolfenpyrad is from about 1:25 to 25:1. In a specific embodiment, the weight ratio of the novaluron to the tolfenpyrad is 1:1. In another specific embodiment, the weight ratio of the novaluron to the tolfenpyrad is 2.5:1. In another specific embodiment, the weight ratio of the novaluron to the tolfenpyrad is 25:1. In another specific embodiment, the weight ratio of the novaluron to the tolfenpyrad is 5:1. In another embodiment, the weight ratio of the novaluron to the tolfenpyrad is 1:5. The weight ratio of the fluoroureide to the tetrazolium amide may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the mesoionic pyrido [1,2- α ] pyrimidinone insecticide in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the mesoionic pyrido [1,2- α ] pyrimidinone insecticide is 1:1. The weight ratio of the fluoroureide to the mesoionic pyrido [1, 2-alpha ] pyrimidinone insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the pyrithione in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the pyrithione is 1:1. The weight ratio of the fluoroureide to the pyrithiofide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the chemical insecticide in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the chemical insecticide is 1:1. The weight ratio of the fluoroureide to the chemical insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the fluazinam in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the flubendiamide is 1:1. The weight ratio of the novaluron to the flubendiamide may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the organofluorine compound in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the organofluorine compound is 1:1. The weight ratio of the fluoroureide to the organofluorine compound may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the chlorfenapyr in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the chlorfenapyr is 1:1. The weight ratio of the novaluron to the chlorfenapyr may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the pyrrole compound in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the pyrrole compound is from about 1:50 to 50:1. In a specific embodiment, the weight ratio of the fluoroureide to the pyrrole compound is 1:1. In another embodiment, the weight ratio of the fluoroureide to the pyrrole compound is 1:10. In another embodiment, the weight ratio of the fluoroureide to the pyrrole compound is 50:1. The weight ratio of the fluoroureide to the pyrrole compound may be selected from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to chlorfenapyr in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to chlorfenapyr is from about 1:50 to 50:1. In a specific embodiment, the weight ratio of the novaluron to the chlorfenapyr is 1:1. In another embodiment, the weight ratio of the novaluron to chlorfenapyr is 1:10. In another embodiment, the weight ratio of the novaluron to chlorfenapyr is 50:1. The weight ratio of the fluoroureide to the chlorfenapyr may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the sulfoximine compound in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the sulfoximine compound is from about 1:5 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the sulfoximine compound is 1:5. In another embodiment, the weight ratio of the fluoroureide to the sulfoximine compound is 100:1. The weight ratio of the fluoroureide to the sulfoximine compound may be selected from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the novaluron to sulfoxaflor in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to the sulfoxaflor is from about 1:5 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the sulfoxaflor is 1:5. In another embodiment, the weight ratio of the novaluron to the sulfoxaflor is 100:1. The weight ratio of the novaluron to the sulfoxaflor may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the fumonic compound in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the fumonioyl compound is 1:1. The weight ratio of the fluoroureide to the fumonic compound may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to dinotefuran in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the dinotefuran is 1:1. The weight ratio of the novaluron to dinotefuran may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the organophosphate compound in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the organophosphate compound is 1:1. In a specific embodiment, the weight ratio of the fluoroureide to the organophosphate compound is 1:10. The weight ratio of the fluoroureide to the organic phosphate compound may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the acephate in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the acephate is 1:10. The weight ratio of the fluoroureide to the acephate may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to malathion in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to malathion is 1:1. In a specific embodiment, the weight ratio of the fluoroureide to malathion is 1:10. The weight ratio of the fluoroureide to malathion may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to the foliar-contacting insecticide in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the foliar contact insecticide is 1:5. In a specific embodiment, the weight ratio of the fluoroureide to the foliar contact insecticide is 100:1. The weight ratio of the fluoroureide to the foliar contact insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to spiromesifen in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the spiromesifen is 1:5. In a specific embodiment, the weight ratio of the novaluron to the spiromesifen is 100:1. The weight ratio of the novaluron to spiromesifen may be selected from the intermediate ranges of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is from about 1:1 to 100:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is from about 1:100 to 1:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is from about 1:1 to 10:1. In a specific embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is 1:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is 100:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is 10:1. In another embodiment, the weight ratio of the fluoroureide to the phenylpyrazole chemical compound is 1:100. The weight ratio of the fluoroureide to the phenylpyrazole chemical compound may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to fipronil in the composition is from about 1:100 to 100:1. In another embodiment, the weight ratio of the novaluron to fipronil is from about 1:1 to 100:1. In another embodiment, the weight ratio of the novaluron to fipronil is from about 1:100 to 1:1. In another embodiment, the weight ratio of the novaluron to fipronil is from about 1:1 to 10:1. In a specific embodiment, the weight ratio of the novaluron to the fipronil is 1:1. In another embodiment, the weight ratio of the novaluron to fipronil is 100:1. In another embodiment, the weight ratio of the novaluron to fipronil is 10:1. In another embodiment, the weight ratio of the novaluron to fipronil is 1:100. The weight ratio of the fluoroureide to fipronil may be selected from the intermediate range of the ratios indicated above.

In one embodiment, the weight ratio of the fluoroureide to the phenylpyrazole insecticide in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the fluoroureide to the phenylpyrazole insecticide is 1:1. The weight ratio of the fluoroureide to the phenylpyrazole insecticide may be selected from the intermediate range of ratios indicated above.

In one embodiment, the weight ratio of the novaluron to tolfenpyrad in the composition is from about 1:100 to 100:1. In a specific embodiment, the weight ratio of the novaluron to the tolfenpyrad is 1:1. The weight ratio of the novaluron to tolfenpyrad may be selected from the intermediate range of ratios indicated above.

Application of the compositions of the invention to plants may also result in increased crop yield.

The pesticidal mixture may be applied via in-furrow spraying, foliar application, sowing, basal application, soil incorporation or soil injection. The pesticidal mixture may be applied at an early stage of the crop cycle, such as for example before or after sowing of the crop.

In further embodiments, the mixture is applied in non-crop areas including, but not limited to, commercial areas, residential areas, grasslands, ornamental plants, shrubs, trees, parks (park), pastures, warehouses, food storage facilities, barns, turf grasses, pastures, fallowland, roadsides, golf courses, parking lots (park), highway sides, power lines, pipes, railways, forests, wellsites, and equipment sites.

In yet another embodiment, the plant includes vegetables such as tomatoes, peppers, cabbages, broccoli, lettuce, spinach, cauliflower, cucurbits, melons, watermelons, cucumbers, carrots, onions, potatoes, tobacco, pome and stone fruits, walnuts, kiwi fruits, strawberries, olives, almonds, pineapples, pears, plums, peaches and cherries, table grapes and vines, citrus fruits (e.g., oranges, lemons, grapefruits and limes), cotton, soybeans, canola, nuts, wheat, barley, maize, sorghum, sunflowers, peanuts, rice, rangelands, corn, coffee, beans, peas, yucca, sugarcane, clover, red peppers and ornamental plants (such as roses).

In further embodiments, plants include cultivated plants that are tolerant to the action of herbicides, fungicides or insecticides due to breeding and/or genetic engineering methods.

In another embodiment, the insect pest belongs to the order Coleoptera (Coleoptera), such as the genus three-tooth beancurd (Acanthosperms spp.) (weevil), the genus phaseolus (Acanthoscelides obtectus) (elephant (common bean weevil)), the genus white wax narrow Jiding (Agrilus planipennis) (white wax borer (emerald ash borer)), the genus click beetle (agriots spp.) (flammule), the species shoulder beetle (Anoplophora glabripennis) (light shoulder beetle (Asian longhorned beetle)), the species flower elephant (Anthonius spp.) (weeville), the species mexico cotton boll (Anthonomus grandis) (cotton weevil), the species aphid, the species of the genus Aphidius (Aphidius spp.) (Aphanus spp.)), the species of the genus tortoise (Aphania spp.) (grub.) (Ataenius spretulus) (Heterous spp.) (Heterous Black Turgrass Ataenius)), the species of the species beet (Atomaria linearis) (Betula beetle) (24)), the species of the genus Betula (brucella) (54), the species of the genus Brupus (brucella) (54, the species of the beetle (brucella) and the species (brucella spp.) (54) The species of beetles include, but are not limited to, yellow tail beetles (Carpophilus hemipteras) (dried fruit beetles (dried fruit beetle)), beetles (Cassida vittata), longicorn species (Cersterna spp), fluoriphylla species (Cerotoma spp.) (Jin Dichong (chrysomeids)), phaseolus vulgaris (Cerotoma trifurcata) (bean leaf beetles), tortoise species (Ceutorthius spp.) (weevil), cabbage seed tortoise (Ceutorhynchus assimilis) (cabbage seed weevil (cabbage seedpod weevil)), completed green tortoise (Ceutorhynchus napi) (cabbage weevil (cabbage color)), flea beetle species (chaetoceroma spp.) (Jin Huachong (chrysomelid)); colaspis species (soil beetle), conoderus scalaris, conoderus stigmosus, li Xiangbi worms (Conotrachelus nenuphar) (Mei Zhui weevil), cotinus nitidis (Green June beetle), asparagus negative mud worms (Crioceris asparagi) (asparagus beetle), horn white beetles (Cryptolestes ferrugineus) (rust flat valley pira (rusty grain beetle)), long horn flat valley pira (Cryptolestes pusillus) (flat grain beetle)), turkish flat valley pira (Cryptolestes turcicus) (turkish flat valley pira (Turkish grain beetle)), ctenonicera species (flammules), weevillus species (Curvularia sp.) (weeville), and the like, fagopyrum species (Tabanus), leptosphaera clathratus (Cylindrocpturus adspersus) (Helianthus annuus (sunflower stem weevil)), mangifera indica scissors She Xiangjia (Deporaus marginatus) (Mangifera armigera (mangoes leaf-cutting weevill), ham beetles (Dermestes lardarius) (ham beetles (larder beele)), white beetles (Dermestes maculates) (Spongilla (hide beele)), eyezoma species (Diabrotica spp.) (pteromalus (chrysoleids)), mexico bean ladybug (Epilachna varivestis) (Mexico ladybug (Mexican bean beetle)), tobacco borers (Faustinus cubae) bark elephant (hyperspectral) or species (hyperspectral), species of the genus hyperspectral (hyperspep), species of the genus hyperspectral (hyperspectral), species of the genus hyperspectus (hyperspectral), species of the species coffee fruit beetle (Hypothenemus hampei) (coffee berry beetle (coffee berry beetle)), species of the genus hyperspectral (Ips pep.) (echinococcidentalis), species of the genus tabacum (ingrowns), species of the genus tabacum (Lasioderma serricorne) (tobacco beetle (cigarette beele)), species of the genus potato beetle (Leptinotarsa decemlineata) (Colorado potato beetle (Colorado potato beetle)), liogenys furtscus, liogenys suturalis, rice water weevil (Lissorhoptrus oryzophilus) (rice water weevil (rice water weevil)), flour beetle species (Lyctus spp.) (wood moths/flour beetles (wood beetles/powder post beetles)), maecolaspis joliveti, megascelis species, corn click beetles (Melanotus communis), spat beetles (Meligethes spp.)), rape tail beetles (Meligethes aeneus) (hupezium anisopliae (blossom beetle)), confetti (melotonia) (common european beetle (common European cockchafer)), obea breve, longicorn beetles (obe lineis), coconut rhinoceros beetles (Oryctes rhinoceros) (norway beetles (date palm beetles)), trade data beetles (Oryzaephilus mercator) (market data beetles (merchant grain beetle)); pinus serrata (Oryzaephilus surinamensis) (data tooth Gu Jiachong (sawtoothed grain beetle)), species of the genus Rhynchosia (Otiorhelychus spp.) (weevil), blackia unguiculata (Oulema melanopus) (black horn negative mud worm (cereal leaf beetle)), pachyrhizus suis (Oulema oryzae), species of the genus Pantotus (Pantoyotus spp.) (weevil) She Bao huperzia species (Phyllophaga spp.) (May/June beetle), june beetle (Phyllophaga cuyabana), phyllotreta species (Phyllotreta spp.) (phyllotopes (chrysomelidas)), apple tiger species (Phynchites spp.), and combinations thereof, japanese beetle (Popillia japonica) (Japanese beetle), daguy (Prostephanus truncates) (Da Gu Changchong (larger grain borer)), valley beetle (Rhizopertha dominica) (Gu Xiao moths (lesser grain borer)), rhizotrogus spp (European beetle), cryptophan spp (Rhynchorus spp), scorpillar spp (wood moths), shenophilus spp (rice moths), rhizopus spp (silvergrass), rhizobium (Sitona lineeatus), trichinella (gray bean weevill), trichinella gracilis (petiolus reevesii) a species of the genus midge (Sitophilus spp.) (weevils), a species of the species midge (Sitophilus granaries) (weevils), a species of the species midge (granary weevils)) a weevil (Sitophilus oryzae), a weevil (rice weevil), a drug corktree (Stegobium paniceum), a drug beetle (drug beetle) Tribolium spp (weevil) species (flour beetles), red corktree (Tribolium castaneum), hybrid Gu Ru (Tribolium confusum) (hybrid corktree (confused flour beetle)), yellow corktree (Trogoderma variabile) (warehouse beetles), and corn beetles (Zabrus tenebioide).

In yet another embodiment, the insect pest belongs to the Diptera (Diptera), such as Aedes species (Aedes spp.) (mosquitoes), alfalfa latent flies (Agromyza frontella) (alfalfa latent flies (alfalfa blotch leafminer)), a latent species ((Agromyza spp.) (leaf miner flies)), a fruit fly species (Anastrepha spp.) (fruit flies), a Caribbean fruit fly (Anastrepha suspensa) (Caribbean fruit flies (Caribbean fruit fly)), a bullous species (Anopheles spp.) (mosquitoes), a fruit fly species (Batrona spp.) (fruit flies), melon fly (Bactrocera cucurbitae) (melon flies), citrus fruit flies (Bactrocera dorsalis) (orange fly (oriental fruit fly)), a small stripe fruit fly species (Centitis spp.) (fruit flies) in the ground (Ceratitis capitata) (fruit fly (Mediterranean fruit fly)), a leaf fly species (Chrysops spp)), deer fly (plague) species (plague) a (37 67), a mosquito species (Batrona spp.) (fruit flies), a fruit fly species (fruit fly) species (37, melon flies (37), melon flies (Bactrocera cucurbitae) (melon flies), orange flies (Bactrocera dorsalis) (fruit flies (37), orange flies (37), a fruit flies (37, fruit flies (37) in the ground (37), a fruit flies (37, a) species (37, a cotton fly species (37) of the beatscheinaria (37), a (37) of the mosquito species (37, a mosquito-borne mosquito, a mosquito species (37, a) Ash plant fly (deltaplacement), drosophila species (Drosophila sp.) (acefly (vinegar fly)), toilet fly species (Fannia sp.) (housefly (filth fly)), yellow-belly toilet fly (Fannia canicularis) (litlehouse fly), ash-belly toilet fly (Fannia scale), large Ma Weiying (Gasterophilus intestinalis) (Ma Weiying (horst fly)), gracillia perseae, bot fly (Haematobia irritans) (horn fly), black fly species (hylemia sp.) (root fly)), rasp (Hypoderma lineatum) (common rasp fly (common cattle grub)), fly (52)); liriomyza spp (leaf flies), cabbage leaf flies (Liriomyza brassica) (snake flies (serpentine leafminer)), sheep ticks (Melophagus ovinus) (sheep ticks), mussel spp (house flies), autumn flies (Musca au-boring) and (house flies (face fly)), house flies (Musca dope) and (house fly), sheep mania flies (Oestrus fly), european wheat flies (oscila flit), and (European wheat flies (swepass fly), beet fly (Pegomyia betae), wheat fly species (Phorbia spp), carrot fly (Psila rosae), cherry fly (Rhagoletis cerasi), cherry fruit fly (cherry fly), apple fruit fly (Rhagoletis pomonella), apple maggot (apple maggot), wheat red plasmagogue (Sitodiplosis mosellana) (orange wheat flower mosquito (orange wheat blossom midge)), stable fly (stomoxys calcitruns) (stable fly), bovine snake species (Tahanus spp), horse fly (horse fly) and mosquito species (Tipula spp).

In yet another embodiment, the insect pest belongs to the order Hemiptera (Hemiptera), such as Lygus lucorum (Acrosternum hilare) (green stink bug), american Gu Changchun (Blissus leucopterus) (Lygus lucorum (branch bug)), lygus lucorum (Calocoris norvegicus) (potto bug), tropical bugs (Cimex heciterus) (tropical bed bug), bugs (Cimex lectularius) (bugs (bed bug)), daghertus fasciatus, dichelops furcatus, black wing red bugs (Dysdercus suturellus) (cotton red bugs (cotton stinker)), edessa meditabunda, flat bugs (Euygaster maura) (cereal bugs (corn bug)), euschistmus heros) brown stink bug (Euschistus servus) (brown stink bug), lygus angustifolia (Helopeltis antonii), lygus lucorum (Helopeltis theivora) (tea plant wilt bug (tea blight plantbug)), stink bug species (lagynoomus spp.) (stink bug), lygus grandis (Leptocorisa oratorius), lygus fern (Leptocorisa varicornis), lygus species (Lygus spp.) (plant bug), lygus lucorum (Lygus hesperus) (western rust stink (western tarnished plant bug)), lygus mandshurica (Maconellicoccus hirsutus), neurocolpus longirostris, lygus lucorum (Nezara virdula) (southern green bug (southern green stink bug)) The species of the genus plant bug (Triatoma spp) ((Phytocoris spp.)) (lygus lucorum), california plant bug (Phytocoris californicus), phytocoris relativus, piezodorus guildingi, lygus quadriphora (Poecilocapsus lineatus) (lygus quadriphora (fourlined plant bug)), psallus vaccinicola, pseudacysta perseae, scaptocoris castanea and the species of the genus plant bug (Triatoma spp.) (blood sucking veitchard (bloodsuckingconenose bug)/huntington bug).

In yet another embodiment, the insect pest belongs to Homoptera (Homoptera), such as pea aphids (Acrythosiphon pisum) (pea Aphis)), myzus persicae (adaptive) species (adaptive) and cabbage whiteflies (Aleurodes proletella) (cabbage white fly), spiral whiteflies (Aleurodicus disperses), silk white flies (Aleurothrixus flccosus) (cotton white fly), white wheel scale (Aluacassis sp.), cotton leafhoppers (Amrasca bigutella), myzus persicae (Aphrophora (leafhopper (leaf hopper)) and aphid (Aonidiella aurantii) (Aphan (California red scale)), aphid (Aphan spin) species (Aphan spin), apple aphids (Aphan) and (Aphan) Aphanotheca (white aphid), apple aphids (Aphan), white nightshade (Aulacorthitm solani) (white sweet potato) and white sweet potato (24) and white beetles (24) and white tubes (24) and (white tubes) Cabbage aphids (Brevicoryne brassicae) (cabbage aphids (bearing) and/or meadow species (Ceroplastes spp.) (scale), meadow scale (Ceroplastes rubens) (meadow wax scale), meadow scale (Chionasapis spp.) (scale), round scale (chrysomyia spp.) (scale), meadow scale (scale), apple powder red aphid (Dysaphis plantaginea) (apple powder red aphid (rosi Aphis) and/or meadow scale), green leafhopper (Eriosoma lanigerum) (apple cotton aphid (woolly apple aphid)), meadow scale (e.g. cicada (cottony cushion scale)), mango (Idioscopus nitidulus) (cicada leaf hopper (24), leaf hopper (67), and/or leaf hopper (67) A wheat eustachian tube aphid (Metopolophium dirhodum), midis longicornis, a peach aphid (Myzus persicae) (Myzus persicae (green peach aphid), a black leafhopper (Nephotettix spp.) (leafhoppers), a black leafhopper (Nephotettix cinctipes) (green leaf hopper), brown planthoppers (Nilaparvata lugens) (brown planthoppers (brown planthopper)), a bran leaf scale (Parlatoria pergandii) (black scale), a black leaf scale (Parlatoria ziziphi) (ebony scale), a corn leafhopper (Peregrinus maidis) (corn leafhopper), a species of the genus Philaenus spp.) (Myzus spinosa), a Myzus persicae (sphalebus) and a Myzus persicae (sphalebus) are all described herein as examples grape root aphid (Phylloxera vitifoliae) (grape root aphid (graphloxera)), de-huperzia (Physokermes piceae) (spruce bud scale), pygeum species (Planococcus spp.) (mealy bugle), mealy species (Pseudococcus spp.) (mealy bugle), pineapple mealy bugle (Pscudococcus brcvipcs) (pineapple mealy bugle (pine apple mealybug)), pear garden bugle (Quadraspidiotus perniciosus) (San Jose scale), aphid species (rhapalos spp.) (aphid), corn She Ya (Rhapalosiphum maida) (corn She Ya (corn leaf) and the like), the plant species include, but are not limited to, aphis citrifolia (Rhapalosiphum padi) (oat bird-cherry aphid)), ericerus species (Saissetia spp.) (scale), canarium lecanii (Saissetia oleae) (black scale), mylabris (Schizaphis graminum) (greenbug), mylabris (Sitobion ave) (UK wheat aphid (English grain aphid)), bemisia alfa (Sogatella furcifera) (Bai Beifei lice (white-backed planthopper)), cactalopia species (Theriopsis spp.) (aphid), toxocerus species (Toumella spp.) (Toxoptera spp.) (aphid), trialeurodes spp.) (white fly (Trialeurodes vaporariorum) (greenhouse white fly (greenhouse whitefly)), heteroptera (Trialeurodes abutiloneus) (yellow fly (bandedwing whitefly)), bemisia spinosa (canthus acutifolia) and (canthus acutus) and (canthus aculeatus).

In yet another embodiment, the insect pest belongs to the Lepidoptera (Lepidoptera), such as asparagus caterpillar (achonata), brown leaf roller (adoropyes spp.), brown leaf roller (adoropyes orana), geotiger (Agrotis spp.), cabbage caterpillar (cutworm), black cabbage moth (black cabbage worm), cotton leaf noctuid (Alabama argillacea) (cotton leaf worm), avocado leaf roller (amoobia canera), navel orange moth (Amyelosis transitella) (navel orange moth), anacamptodes defectaria, cotton sliver moth (Anarsia lineatella) (peach stripe moth), cotton moth (peach stripe moth) yellow hemp bridge Emei (Anomis sabuli jera) (yellow loopers), white bean loopers (Anticarsia gemmatalis) (yellow bean caterpillars (velvetbean caterpillar)), fruit tree leaf rollers (Archips argyrospila) (fruit tree leaf rollers (fruittree leafroller)), rose leaf rollers (Archips rosana), species of the genus armyworms (armyworms) (tortricid moths) of the family armyworms (orange torricidae), orange loopers (Argyrotaenia citrana) (orange torricles), gamma spodoptera (automatic gamma), bonagota cranaodcs, rice leaf rollers (borborborborrelia), rice leaf rollers (rice leaf rollers), cotton leaf miner (Bucculatrix thurberiella) (cotton leaf miner (cotton leafperforator)), a species of the genus meloidogyne (Caloptilia spp.) (leaf miner), a tobacco leaf moth (capra reiciculosa), a peach moth (Carposina niponensis) (peach moth (peach fruitus)), a species of the genus graminiella (Chilo spp.), a mango spodoptera (Chlumetia transversa) (cerbera fulgiperda (mango shoot borer)), a rose roll moth (Choristoneura rosaceana) (prodenia litura (obliquebanded leafroller)), a species (chrysodeyixis spp.), a rice leaf roller She Yeming (Cnaphalocerus medinalis) (grass leaf roller), a species of the species bean flour butterfly (Colias spp.); the species of carpentry moth (Conpomorpha cramerella), carpentry moth (Cossus), meadow moth (carpenter moth), meadow moth (Crambus spp)), yellow bristletail (Sod webworm), yellow bristletail (Cydia furbrana) (plutella xylostella) (plus fructi moth), yellow bristletail (Cydia molesta) (oriental fruit moth), yellow pea pod Emeiboa (Cydia nigrana) (pea pod moth), codia pomonella (codling moth), darna diduca, silk moth (Diaphania spp)) (stem borer), the species of the genus borer (diapraea spp.) (stem borer), sugarcane borer (Diatraea saccharalis) (sugarcane borer (sucara borer)), southwest corn stalk borer (Diatraea graniosella) (southwest corn borer (southwester corn borer)), spodoptera species (Earias spp.) (cotton bollworm (bollworm)), earworm (earia insuloata) (Egypti bollworm (Egyptian bollworm)), armyworm emerald (earia vitella) (bollworm (rough northern bollworm)), ecdytopopha aurantianum, southern corn seedling borer (Elasmopalpus lignosellus) (corn borer (lesser cornstalk borer)), light brown apple moth (Epiphysias postruttana) (apple leaf roller (light brown apple moth)); pink moth (Ephesia spp.) (Pink moth) in the genus of Pink moth (flower moth), pink moth (Ephestia cautella) (almond moth), nicotiana tabacum (Ephestia elutella) (tobacco borer (tobbaco moth)), mediterranean powder borer (Ephestia kuehniella) (Mediterran) in the genus of Epimedes, fagus (Epinotia apoma), musa butterfly (Erionota thiax) (banana butterfly), ligustrum (Eupoecilia ambiguella) (grape leaf roller moth), primordica (Euxoa augisia) (army cutworm), epimedes (army cutworm), A species of spodoptera (fertia spp.) (root cutting worm), a species of spodoptera (Gortyna spp.) (stem borer), a fruit moth of oriental fruit (Grapholita molesta) (shirttail (oriental fruit moth)), a leaf roller (Hedylepta indicata) (bean leaf weber), a species of spodoptera (Helicoverpa spp.) (noctuid (non-moving), a cotton bollworm (Helicoverpa armigera) (cotton bollworm)), a fruit moth (Helicoverpa zea) (bollworm/corn earworm), a species of spodoptera (Helicoverpa spp.) (moth)), a fruit moth (cotton bollworm/corn earworm) tobacco budworm (Heliothis virescens) (tobacco budworm larva), cabbage loopers (helula undalis) (cabbage borer), indiibela species (root borer), tomato stem moths (Keiferia lycopersicella) (tomato pinworm), front Bai Chiye borer (Leucinodes orbonalis) (eggplant yellow borer (eggplant fruit borer)), schlieren (Leucoptera malifoliella), tenacula species (lithiolecetis spp.), grape leaf moths (lobisia botana) (grape fruit moths (grape fructi), loxagkistrodia species (night moths), bean white line rootworm (Loxagrotis albicosta) (western bean moths (western bean cutworm)) Lymantria dispar (Lymantria dispar), lyonetia nectar (Lyonetia nectar), apocynum alfa (apple leaf miner), oil palm bag moth Mahasena corbetti (oil palm bag worm), europe (yellow cat five), cabbage loopers Mamestra brassicae (cabbage armyworm), bean pod borer Maruca testulalis (bean pod borer), bag moth Mythimna unipuncta (yellow armyworm), yellow armyworm Mythimna unipuncta (pirate armyworm) the feed comprises the following components of a tomato budworm (Neoleucinodes elegantalis) (bristletail (small tomato borer)), a three-point water moth (Nymphula depunctalis) (rice leaf roller (rice caseworm)), a winter moth (Operophthera brumata) (winter geometrid moth), a European corn borer (Ostrinia nubilalis) (European corn borer (European corn borer)), an Oxydia vesulia Jiang brown moth (Pandemis cerasana) (common grape leaf roller (common currant tortrix)), apple brown moth (Pandemis heparana) (apple brown leaf roller (brown apple tortrix)), african Dalmon ptera (Papilio demodocus), red bell moth (Pectinophora gossypiella) (pink bollworm), jiang noctuid species (Peridroma spp.) (rootworm), african red bell moth (Pectinophora gossypiella), gekko Swinhonis (Peridroma saucia) (bean spodoptera (variegated cutworm)), coffee leaf miner (Perileucoptera coffeella) (milk coffee leaf miner (white coffee leafminer)), potato tuber moth (Phthorimaea operculella) (potato stem moth (potato tuber moth)), citrus leaf miner (Phyllocnisitis citrella), philippine species (Phyllonorycter spp.) (leaf miner), pinus rapae (Pieris rapae) (exotic cabbage caterpillar (imported cabbageworm)), first-pass green noctuid (Plathypena scabra), indian Gu Bane (Plodia interpunctella) (black moth (Indian meal mole), plutella xylostella (Plutella xylostella) (diamond back moth (diamondback moth)), grape berry moth (Polychrosis viteana) (grape leaf roller moth (grape berry mole)) fruit moth (Prays endocards), fruit moth (Prsys oleracea) (olive moth)), armyworm species (pseudoaletia spp.) (noctuid), armyworm (Pseudaletia unipunctata) (march), soybean noctuid (Pseudoplusia includens) (soybean looper)), sunflower geometrid (rachiplus nu), tryporyza incertulas (Scirpophaga incertulas), stem-borer species (Sesamia spp.) (stem borer), stem-borer (Sesamia insolens) (powder rice stem borer (pink rice stemborer)), powder stem borer (Sesamia nonagrioides), copper brown thorn moth (setoa nitens), the species Spodoptera (Spodoptera) may be selected from the group consisting of moths (Sitotroga cerealella) (wheat moth (Angoumois grain moth)), grape armyworm (Sparganothis pilleriana), spodoptera species (Spodoptera spp.) (armyworm), beet armyworm (Spodoptera exigua) (beet armyworm), spodoptera litura (Spodoptera frugiperda) (fall armyworm)), southern Spodoptera (Spodoptera oridania) (southern armyworm (southern armyworm)), spodoptera species (synanthadon spp.) (root worm), thermo basilide, thermisia gemmatalis, clothes moth (Tineola bisselliella) (negative bag moth (webbing clothes moth)), pink moth (Trichoplusia ni) (webber), guava species (yellow moths) (Zeuzera) and yellow moths (yellow moths).

In yet another embodiment, the insect pest belongs to the order Orthoptera (orthotera), such as the phylum samplex (Mormon cricket), the Gryllotalpa (mole cricket), the Toyama species (Melanopsis spp.) (grasshopper), the class Alternaria sp75 (Microcentrum retinerve) (horners (angularwinged katydid)), the Pterophyllella species (desert), the Thymus bologna (chistocerca gregaria), the Leptosperms (Scudderia furcata) (the Leptospermum (forktailed bush katydid)), and the Black horns (Valanga nigricorni).

In yet another embodiment, the insect pest belongs to the order Thysanoptera, such as tobacco brown Thrips (Frankliniella fusca) (tobacco Thrips (tobacco threp)), frankliniella occidentalis (Frankliniella occidentalis) (frankliniella occidentalis (western flower thrip)), comb-deficiency Thrips (Frankliniella shultzei), williams Thrips (Frankliniella williamsi) (corn threp), greenhouse Thrips (Ileliothrips haemorrhaidalis) (greenhouse Thrips (greenhouse threp)), abdominal Thrips (Riphiphorothrips cruentatus), hard Thrips species (scirtothreps spp.), platycodon Thrips (Scirtothrips cirri) (citrus Thrips (citruss threp)), tea Huang Jima (Scirtothrips dorsalis) (yellow tea Thrips (yeipop)), taeniothrips rhopalantennalis and Thrips species (threps sp.).

In some embodiments, the insects include, but are not limited to spider mites, spodoptera species, aphid species, myzus species, bemisia, trialeurodes vaporariorum (Trialurodes vaporariorum), tomato leaf miners, tea wing bugs, drosophila species, flower thrips species, tetranichus species, and lygus species.

The effective application rate of the fluoroureide and one of the active compounds denoted as compound II as defined above may generally not be defined, as it varies depending on various conditions such as the type of formulation, weather conditions, crop type and pest type.

The rate of application of the combination in the field may vary depending on the desired effect. In the examples, the application rate of the mixture according to the invention is, depending on the desired effect, from 1g ai/ha to 1000g ai/ha, in particular from 1 to 500g ai/ha, more in particular from 1 to 100g ai/ha.

Accordingly, the application rate of the fluoroureide in the field is generally from 1 to 1000g/ha. In some embodiments, the application rate of the fluoroureide is generally from 1 to 500g/ha, in particular from 1-100g/ha.

Accordingly, the application rate of one of the active compounds, denoted compound II, as defined above, in the field is generally from 1 to 1000g/ha. In some embodiments, the application rate of one of the active compounds denoted as compound II as defined above is generally from 1 to 500g/ha, in particular from 1 to 100g/ha,

The present subject matter further relates to a method for reducing the total amount of insecticidal active compound necessary for controlling undesired pests by: a) The fluoroureide is administered at an administration rate of from about 25% to about 75% of the recommended administration rate and b) one of the active compounds, denoted compound II, as defined above is administered.

That is, the fluoroureide and each of the active compounds denoted as compound II as defined above may be administered together or sequentially. In one example, the fluoroureide and the active compound, denoted as compound II, as defined above are prepared separately and the individual formulations are applied as such or diluted to a predetermined concentration. In a further example, the fluoroureide and the active compound denoted compound II as defined above are prepared separately and the formulation is mixed when diluted to a predetermined concentration. In another example, a fluoroureide is formulated with one of the active compounds denoted as compound II as defined above, and the formulation is applied as is or diluted to a predetermined concentration.

As a representative example only, the fluoroureide and methoxyfenozide may be administered simultaneously (i.e., together or separately) or sequentially, in which case the sequence generally has no effect on the outcome of the control measures. In one example, the fluoroureide and methoxyfenozide are prepared separately and the individual formulations are administered as they are or diluted to a predetermined concentration. In further examples, the fluoroureide and methoxyfenozide are prepared separately and these formulations are mixed as they are diluted to a predetermined concentration. In another example, the fluoroureide and methoxyfenozide are formulated together and the formulation is applied as is or diluted to a predetermined concentration.

In some embodiments, the components of the mixtures or compositions of the present disclosure are applied at least once during the growing season.

In some embodiments, the components of the mixtures or compositions of the present disclosure are applied two or more times during the growing season.

In some embodiments, the components of the mixtures or compositions of the present disclosure are applied as soil fertilization. In some embodiments, the mixtures or compositions described herein are applied as foliar applications. In some embodiments, the components of the mixture or composition thereof are applied as a seed treatment.

In some embodiments, the composition is a synergistic composition.

In yet another embodiment, the synergistic composition may be applied as various mixtures or combinations of the fluoroureide and one of the active compounds denoted as compound II as defined above, either in a single "ready-to-use" form or in a combined spray mixture consisting of individual formulations of the single active ingredients, such as in a "tank mix" form.

In further embodiments, the synergistic composition may be applied as various mixtures or combinations of the fluoroureide and one of the active compounds denoted as compound II as defined above, either in a single "ready-to-use" form or in the form of a combined spray mixture consisting of individual formulations of the single active ingredients, such as in a "tank mix" form.

As a representative example only, the composition is applied in the form of a ready-to-use formulation comprising a fluoroureide and a bishydrazide insecticide (e.g., methoxyfenozide). Such formulations may be obtained by combining an effective amount of the active ingredient with an agriculturally acceptable carrier, surfactant or other convenient administration adjuvants commonly used in formulation technology.

For a specific representative example, the compositions of the present invention are preferably applied in the form of a ready-to-use formulation comprising a fluoroureide and methoxyfenozide, which formulation may be obtained by combining the two active ingredients with an agriculturally acceptable carrier, surfactant or other convenient application adjuvants commonly used in formulation technology.

The compositions of the invention may be used or prepared in any conventional form, for example as Wettable Powders (WP), emulsion Concentrates (EC), microemulsion concentrates (MEC), water Soluble Powders (SP), water soluble concentrates (SL), suspoemulsions (SE), oil Dispersions (OD), concentrated emulsions (BW) such as oil-in-water and water-in-oil emulsions, sprayable solutions or emulsions, capsule Suspensions (CS), suspension Concentrates (SC), suspension concentrate powders (DP), oil miscible solutions (OL), seed dressing products, granules in the form of microparticles (GR), spray, coated and absorbent particles, particles for soil fertilization or broadcasting, water soluble particles (SG), water dispersible particles (WDG), ULV formulations, microcapsules or waxes. These individual formulation types are known in the art.

According to an embodiment, the composition comprises at least one additional component selected from the group of surfactants, solid diluents and liquid diluents.

Such compositions may be formulated using agriculturally acceptable carriers, surfactants or other convenient administration adjuvants commonly used in formulation technology, as known in the art.

Examples of suitable liquid carriers potentially suitable for use in the compositions of the present invention include, but are not limited to, water; aromatic hydrocarbons such as alkylbenzene and alkylnaphthalene; alcohols such as cyclohexanol and decanol; ethylene glycol; propylene glycol; dipropylene glycol; n, N-dimethylformamide; dimethyl sulfoxide; dimethylacetamide; n-alkylpyrrolidones, such as N-methyl-2-pyrrolidone; a paraffinic hydrocarbon; various oils such as olive oil, castor oil, linseed oil, tung oil, sesame oil, corn oil, peanut oil, cottonseed oil, soybean oil, rapeseed oil or coconut oil; fatty acid esters; ketones such as cyclohexanone, 2-heptanone, isophorone and 4-hydroxy-4-methyl-2-pentanone; etc.

Examples of suitable solid carriers potentially suitable for use in the compositions of the present invention include, but are not limited to, minerals such as silica gel, silicate, talc, kaolin, mica, clay, limestone, bentonite, lime, chalk, red bayerite, mirabilite, loess, clay, dolomite, zeolite, diatomaceous earth, calcium carbonate, calcium sulfate, magnesium oxide, sodium carbonate and sodium bicarbonate, and sodium sulfate; a land synthetic material; fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea and plant-derived products such as cereal flour, bark flour, wood flour and nut shell flour; cellulose powder; as well as other solid carriers.

Examples of suitable surfactants include, but are not limited to, nonionic, anionic, cationic and amphoteric types such as alkoxylated fatty alcohols, ethoxylated polysorbates (e.g., tween 20), ethoxylated castor oils, lignosulfonates, fatty acid sulfonates (e.g., lauryl sulfonate), phosphate esters (such as alcohol alkoxylate phosphate esters), alkyl phenol alkoxylate phosphate esters and styryl phenol ethoxylate phosphate esters, sulfonated naphthalene and naphthalene derivatives condensates with formaldehyde, naphthalene or naphthalene sulfonic acid condensates with phenol and formaldehyde, alkylaryl sulfonates, ethoxylated alkylphenols and aryl phenols, polyvinyl alcohol, sorbitol esters, metal, sodium salts of lignosulfonates, tristyrylphenol ethoxylate phosphate esters, aliphatic alcohol ethoxylates, alkylphenol ethoxylate, ethylene oxide/propylene oxide block copolymers, graft copolymers and polyvinyl alcohol-vinyl acetate copolymers. Other surfactants known in the art may be used as desired.

Other ingredients such as wetting agents, defoamers, binders, neutralizers, thickeners, binders, chelating agents, fertilizers, biocides, stabilizers, buffers, or antifreeze agents may also be added to the compositions of the present invention to increase the stability, density, and viscosity of the compositions.

The aqueous use forms may be prepared from emulsion concentrates, suspensions, pastes, wettable powders or water dispersible granules by the addition of water. For the preparation of emulsions, pastes or oil dispersions, the composition itself or the components dissolved in the oil or solvent may be homogenized in water by wetting agents, tackifiers, dispersants or emulsifiers. Alternatively, concentrates may be prepared which contain the active agent, wetting agent, viscosity increasing agent, dispersing agent or emulsifying agent and, if desired, solvent or oil, these concentrates being suitable for dilution with water.

In some embodiments, the mixture, combination, composition or synergistic mixture or composition comprises one or more additional active ingredients. In some embodiments, the mixture or synergistic mixture comprises one or more additional inactive ingredients.

The compositions of the present invention may comprise additional crop protection agents, such as insecticides, herbicides, fungicides, bactericides, nematicides, molluscicides, growth regulators, biological agents, fertilizers or mixtures thereof. However, for the avoidance of doubt, it is to be understood that such additional crop protection agents are not necessary to achieve the desired pest control (as achieved by the combination of the present invention).

In another embodiment, the invention provides a kit comprising a synergistic pesticidal composition as described herein or components thereof. Such kits may comprise one or more additional active and/or inactive ingredients in addition to the active ingredients described above, in the provided pesticidal compositions or separately.

As described above, the compositions, kits, and methods described herein exhibit synergistic effects. There is a synergistic effect as long as the combined effect of the active ingredients is greater than the sum of the individual effects of each ingredient. Thus, a synergistically effective amount (or an effective amount of a synergistic composition or combination) is one that exhibits a pesticidal activity greater than the sum of the activities of the individual components.

Application method

The present invention provides a method for controlling insects by contacting the insects or their food supply, habitat, breeding grounds or their locus with an effective amount of any of the mixtures or compositions disclosed herein to thereby control the insects.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a bishydrazide insecticide in a ratio from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and methoxyfenozide in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and methoxyfenozide in a ratio of from 1:1 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:100 ratio of novaluron and spinetoram to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 100:1 ratio of novaluron and spinetoram to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect tomato leaf miner (t.absoluta) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and spinetoram to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a bishydrazide insecticide in a ratio from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and methoxyfenozide in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and methoxyfenozide to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:5 to 5:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of one of a fluoroureide and an aryl isoxazoline, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and isoxaflutole in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and isoxaflutole to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of one of a fluoroureide and a diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a ratio of novaluron and tolfenpyrad from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a ratio of novaluron and tetrazolium amide from 1:5 to 5:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the mesoionic pyrido [1,2- α ] pyrimidinone insecticides in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and pyrithione in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and pyrithione to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a chemical insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and fluazinam in a ratio from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and fluazinam to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and an organofluorine compound in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and chlorfenapyr in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and chlorfenapyr to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a fumonioyl compound in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and dinotefuran in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and dinotefuran to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and fipronil in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and fipronil in a ratio of from 1:1 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and tolfenpyrad in a ratio of from 1:100 to 100:1, to thereby control said insect.

In an embodiment, the present invention provides a method for controlling insect spodoptera littoralis (s.) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and tolfenpyrad to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and spinosad in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and spinosad in a ratio of from 1:1 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:1 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and malathion in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:1 ratio of novaluron and malathion to thereby control said insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect frankliniella occidentalis (f.occidentalis) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and fipronil in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spinetoram in a ratio of from 1:5 to 5:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of one of a fluoroureide and a meta-diamide, which is a GABA-gated chloride channel allosteric modulator insecticide, in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and bromofluorobenzene bisamide at a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and bromofluorobenzene bisamide in a ratio of from 1:1 to 10:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of one of a fluoroureide and a diamide, which is a highly specific ranitidine receptor (RyR) modulator insecticide, in a ratio of from 1:100 to 100:1, to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a ratio of novaluron and tolfenpyrad from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling Spodoptera frugiperda (S.frugiperda) of Cordyceps sinensis by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a ratio of novaluron and tetrazolium amide from 2.5:1 to 25:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the acetyl-coa carboxylase (ACC) inhibitor insecticides in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spirotetramat in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:100 ratio of novaluron and spirotetramat to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a sulfoximine compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and sulfoxaflor in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and sulfoxaflor in a ratio of from 1:5 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and acephate in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:10 ratio of novaluron and acephate to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a foliar contact insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spiromesifen in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect myzus persicae (m.persicae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 100:1 ratio of novaluron and spiromesifen to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the acetyl-coa carboxylase (ACC) inhibitor insecticides in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spirotetramat in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spirotetramat in a ratio of from 1:100 to 1:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a pyrrole compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and chlorfenapyr in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Tetranychus urticae (T.urticae) by: contacting an insect or its food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of novaluron and chlorfenapyr in a ratio of from 1:10 to 50:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect bemisia tabaci (b.tabaci) by: contacting an insect or a food supply, habitat, breeding area or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a chord organ TRPV (vanilloid instantaneous receptor potential) channel modulator insecticide in a ratio of from 1:100 to 100:1, to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect bemisia tabaci (b.tabaci) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and hydroprene in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect bemisia tabaci (b.tabaci) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and hydroprene in a ratio of from 1:5 to 5:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of novaluron and malathion in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 1:10 ratio of novaluron and malathion to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or food supply thereof, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a foliar contact insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and spiromesifen in a ratio of from 1:100 to 100:1 to thereby control said insect.

In an embodiment, the present invention provides a method for controlling the insect Aphis gossypii (A.gossypii) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a 1:5 ratio of novaluron and spiromesifen to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect theaters (h.halys) by: contacting an insect or food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound insecticide in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect theaters (h.halys) by: contacting an insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of novaluron and fipronil in a ratio of from 1:100 to 100:1 to thereby control the insect.

In an embodiment, the present invention provides a method for controlling insect theaters (h.halys) by: contacting an insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a 10:1 ratio of novaluron and fipronil to thereby control the insect.

The present invention provides a method of protecting a plant from attack or infestation by insects, the method comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of any of the mixtures or compositions disclosed herein to thereby protect the plant from attack or infestation by insects.

The present invention provides a method of enhancing knockdown activity and/or prolonged control comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of any of the mixtures or compositions disclosed herein, to thereby enhance knockdown activity and/or prolonged control.

The present invention provides a method for increasing resistance to a fluoroureide, the method comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of any of the mixtures or compositions disclosed herein, to thereby increase resistance to the fluoroureide.

The present invention provides a method for enhancing root systems and/or enhancing crop plant development and/or enhancing crop plant vigor and/or improving plant potential yield, the method comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, to a locus thereof or to propagation material thereof.

The present invention provides a method for enhancing plant development comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, the locus thereof or propagation material thereof, to thereby enhance plant development.

The present invention provides a method for enhancing a root system comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, locus thereof or propagation material thereof, to thereby enhance the root system.

The present invention provides a method for enhancing plant vigor comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, the locus thereof or propagation material thereof, to thereby enhance plant vigor.

The present invention provides a method for improving the potential yield of a plant, the method comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, the locus thereof or propagation material thereof, to thereby improve the potential yield of a plant.

The present invention provides a method for regulating plant growth comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, the locus thereof or propagation material thereof, to thereby regulate plant growth.

The present invention also provides a method for enhancing plant growth comprising applying an effective amount of any of the mixtures and/or compositions disclosed herein to one or more plants, the locus thereof or propagation material thereof.

In some embodiments, the mixtures and formulations of the present invention are administered as a knockdown treatment.

In some embodiments, the mixtures and formulations of the present invention are applied to provide extended insecticidal control.

The following examples illustrate the practice of the invention in some of its embodiments but should not be construed as limiting the scope of the invention. Other embodiments will be apparent to those skilled in the art from consideration of the specification and practice of the invention. It is intended that the specification (including examples) be considered as exemplary only, with a limitation on the scope and spirit of the invention.

Examples

A synergistic effect exists whenever the effect of a combination of active ingredients is greater than the sum of the individual effects of each ingredient. Thus, a synergistic combination is a combination of active ingredients that has an effect that is greater than the sum of the effects of each active ingredient alone, and a synergistically effective amount is an effective amount of the synergistic combination.

The Colby method was used to determine whether there was a synergistic effect of the combination of active ingredients. According to Colby, the intended action (E) of the active ingredient a+b is:

where E = expected efficacy, a and B = efficacy of the two active ingredients a and B at the given dose.

When the observed percent control of (O) is greater than the expected percent (E) for the combination, there is a synergistic effect. The co-ratio (R) is calculated as the ratio between the expected value and the observed value. If the synergy ratio between observed and expected (R) >1, then synergy is exhibited, if r=1, then the effect is additive, and if R <1, then the mixture is antagonistic.

For a more detailed description of the Colby formula, see Colby, s.r. "Calculating synergistic and antagonistic responses of herbicide combination [ calculate synergistic and antagonistic responses of herbicide combinations ]," ingredients [ Weeds ], volume 15, pages 20-22; 1967; see also Limpel et al, proc. NEWCC 16:48-53 (1962).

Insecticidal compounds a (fluoroureides) and B (mixing partners) were formulated as equivalent suspension concentrates to eliminate the effect of different formulation inerts on biological activity. Efficacy of the insecticidal composition was evaluated with reference to a scale of 0% to 100% compared to untreated control plots. 0 means no damage and 100 means complete elimination of harmful pests.

Representative experiments were conducted to evaluate insecticidal control of the combination of novaluron, compound II (i.e., methoxyfenozide) and novaluron against spodoptera litura (Spodoptera littoralis) larvae.

Experiment by reacting a fluoroureideAnd methoxyfenozide +.>Is applied separately or together. The composition is diluted with water to the stated concentration of active compound.

The following active ingredients and mixtures thereof were evaluated:

fluoroureide: 0.01mg a.i./liter

Methoxyfenozide: 0.01mg a.i./liter

Fluoroureide + methoxyfenozide 0.01mg a.i./l +0.01mg a.i./l

To evaluate insecticidal control of the fluoroureide and methoxyfenozide alone and in binary mixtures, castor leaves were treated with the treatments listed above. The treated leaves were exposed to age 3 spodoptera littoralis for 4 days and larvae were exposed on untreated leaves for another 4 days. Larval mortality was determined on days 4 and 8. These treatments consisted of 3-5 replicates of 10 larvae each.

Table 1 below summarizes the calculated synergy of the mixture of novaluron and methoxyfenozide at each evaluation period (Colby's synergistic ratio).

Table 1: effect of tank mixture of novaluron + methoxyfenozide on controlling spodoptera littoralis

The above table clearly shows that the observed activity of the active compound combinations according to the invention is greater than the calculated activity, i.e. that there is a synergistic effect.

Larval Weight Gain (LWG) was also measured in order to determine the effectiveness of the mixture of novaluron and methoxyfenozide when compared to the administration of novaluron and methoxyfenozide alone.

Table 2 below also summarizes the calculated synergy of the mixture of novaluron and methoxyfenozide against another pest (Colby ratio) at each evaluation period:

Table 2: the fluoroureide + methoxyfenozide against the tomato leaf miner (t.absoluta),

table 3 below summarizes the Larval Weight Gain (LWG) (compared to the control) which was determined 4 days after treatment of the mixture of fluoroureide and methoxyfenozide.

Table 3: effect of tank mixture of novaluron + methoxyfenozide on LWG of spodoptera littoralis

As can be seen in table 3, neither the novaluron nor the methoxyfenozide alone had any effect on weight gain of the spodoptera littoralis larvae. However, when the novaluron and methoxyfenozide were combined, the growth of larvae was reduced by 57% when compared to the growth of larvae in the control treatment. This indicates that when combined, the novaluron and methoxyfenozide have a greater effect on the feeding activity of spodoptera littoralis.

Similarly, the following experiments were performed on other fluoroureide mixtures on various pests, the results of which are summarized in the following table:

table 4: fluoroureide + spinosad

A)

B)

C)

Table 5: fluoroureide + ethylspinosad

A)

B)

C)

D)

E)

F)

Table 6: fluoureide + spirotetramat

A)

B)

C)

D)

E)

Table 7: fluroyl urea and hydroprene

Table 8: fluroyl urea and isoxazolyl carboxamides

Table 9: fluroyl urea and bromothalonil diamide

Table 10: fluroyl urea and tetrazolium carboxamides

A)

B)

Table 11: fluoroureide+dichloropyrimidine

Table 12: fluroyl urea and flubendiamide

Table 13: fluroyl urea and chlorpyrad

Table 14: fluroyl urea and chlorfenapyr

A)

B)

C)

Table 15: fluroyl urea and sulfoxaflor

A)

B)

Table 16: fungicide and dinotefuran

Table 17: fluoroureide + acephate

A)

B)

Table 18: fluoroureide plus malathion

A)

B)

Table 19: fluroyl urea and spiromesifen

A)

B)

Table 20: fluroyl urea + fipronil

A)

B)

C)

D)

E)

Table 21: fluroyl urea and tolfenpyrad

While the invention has been shown and described with reference to the preferred embodiments thereof, it will be understood by those skilled in the art that many alternatives, modifications and variations may be made thereto without departing from the spirit and scope thereof. Accordingly, it is intended to embrace all such alternatives, modifications and variations that fall within the spirit and broad scope of the appended claims.

All publications, patents, and patent applications mentioned in this specification are herein incorporated in their entirety by reference into the specification, to the same extent as if each individual publication, patent, or patent application was specifically and individually indicated to be incorporated herein by reference.

Claims

1. A pesticidal mixture comprising as active compounds:

i) Compound I which is a fluoroureide of formula (I)

II) at least one active compound II selected from the group a.1 to a.26:

A.16. an organofluorine compound selected from the group comprising chlorpyrad;

A.18. a pyrrole compound selected from the group comprising chlorfenapyr;

A.19. a sulfoximine compound selected from the group comprising sulfoxaflor;

A.24. a tetramic acid insecticide selected from the group comprising dispiro;

A.26. an ecdysteroid compound selected from the group comprising ecdysone.

2. The pesticidal mixture of claim 1, wherein the bishydrazide insecticide is methoxyfenozide.

3. The pesticidal mixture of claim 1, wherein the pyrethroid insecticide is tau-fluvalinate.

4. The pesticidal mixture of claim 1, wherein the spinosad insecticide is spinosad.

5. The pesticidal mixture of claim 1, wherein the spinosad insecticide is spinetoram.

6. The pesticidal mixture of claim 1, wherein the tetramic acid, cyclic ketoenol insecticide is methoxypiperidine ethyl.

7. The pesticidal mixture of claim 1, wherein the tetramic acid, cyclic ketoenol insecticide is spirotetramat.

8. The pesticidal mixture of claim 1, wherein the METI insecticide is tolfenpyrad.

9. The pesticidal mixture of claim 1, wherein the pyridine organic compound is flonicamid.

10. The pesticidal mixture of claim 1, wherein the chordal organ TRPV channel modulator is pymetrozine.

11. The pesticidal mixture of claim 1, wherein the chordal organ TRPV channel modulator is dicyclanil.

12. The pesticidal mixture of claim 1, wherein the aryl isoxazoline is a fluorooxamide.

13. The pesticidal mixture of claim 1, wherein the arylisoxazoline is isoxazolonamide.

14. The pesticidal mixture of claim 1, wherein the meta-diamide is bromofluorobenzene bisamide.

15. A pesticidal mixture as in claim 1 wherein said diamide is cycloartemia amide.

16. The pesticidal mixture of claim 1, wherein the diamide is tetrazolium-chlorfenapyr.

17. The pesticidal mixture of claim 1, wherein the arylalkoxypyrimidine compound is saflufenacil.

18. The pesticidal mixture of claim 1, wherein the mesoionic pyrido [1,2- α ] pyrimidinone is dichloropyrimidine.

19. The pesticidal mixture of claim 1, wherein the quinoline insecticide is flubendiamide.

20. The pesticidal mixture of claim 1, wherein the chemical insecticide is flubendiamide.

21. The pesticidal mixture of claim 1, wherein the aryl ethyl sulfonyl compound is oxazolesulfonyl-chlorfenapyr.

22. The pesticidal mixture of claim 1, wherein the organofluorine compound is aminopyrazole.

23. The pesticidal mixture of claim 1, wherein the pyrazole carboxamide insecticide is metaxazole.

24. The pesticidal mixture of claim 1, wherein the pyrrole compound is chlorfenapyr.

25. The pesticidal mixture of claim 1, wherein the sulfoximine compound is sulfoxaflor.

26. The pesticidal mixture of claim 1, wherein the fumonic compound is dinotefuran.

27. The pesticidal mixture of claim 1, wherein the organophosphate compound is acephate.

28. The pesticidal mixture of claim 1, wherein the organophosphate compound is malathion.

29. The pesticidal mixture of claim 1, wherein the foliar contact insecticide is spiromesifen.

30. The pesticidal mixture of claim 1, wherein the phenylpyrazole chemical compound is fipronil.

31. The pesticidal mixture of claim 1, wherein the tetramic acid insecticide is a dispiro.

32. The pesticidal mixture of claim 1, wherein the phenylpyrazole insecticide is tolfenpyrad.

33. A pesticidal mixture according to claim 1, wherein the ecdysteroid compound is ecdysone.

34. A pesticidal mixture according to any one of claims 1 to 33 wherein the mixture exhibits a synergistic effect.

35. A pesticidal mixture according to any one of claims 1 to 34, wherein the fluoroureide and at least one active compound II as defined in claim 1 are applied together or sequentially.

36. The pesticidal mixture of any one of claims 1-35, wherein the weight ratio of the fluoroureide to the at least one active compound II as defined in claim 1 is from 1:100 to 100:1.

37. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the bishydrazide insecticide is from 1:100 to 100:1.

38. The pesticidal mixture of claim 37, wherein the weight ratio of novaluron to methoxyfenozide is from 1:1 to 100:1.

39. A pesticidal mixture according to claim 34 wherein the weight ratio of the fluoroureide to the spinosad insecticide is from 1:100 to 100:1.

40. A pesticidal mixture according to claim 39, wherein the weight ratio of the fluoroureide to spinosad is from 1:1 to 1:100.

41. A pesticidal mixture according to claim 39, wherein the weight ratio of the fluoroureide to the spinetoram is from 100:1 to 1:100.

42. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to one of the acetyl-coa carboxylase (ACC) inhibitor insecticides is from 1:100 to 100:1.

43. A pesticidal mixture according to claim 42, wherein the weight ratio of the fluoroureide to spirotetramat is from 1:1 to 1:100.

44. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to one of the chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticides is from 1:100 to 100:1.

45. A pesticidal mixture according to claim 44, wherein the weight ratio of the novaluron to the hydroprene is from 1:5 to 5:1.

46. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to one of the arylisoxazolines, which is a gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticide, is from 1:100 to 100:1.

47. A pesticidal mixture according to claim 46, wherein the weight ratio of novaluron to isoxaflutole is 1:1.

48. The pesticidal mixture of claim 34, wherein the weight ratio of one of the fluoroureide to the meta-diamide, which is a GABA-gated chloride channel allosteric modulator insecticide, is from 1:100 to 100:1.

49. A pesticidal mixture according to claim 48, wherein the weight ratio of the fluoroureide to the bromofluorobenzene bisamide is from 1:1 to 10:1.

50. A pesticidal mixture according to claim 34, wherein the weight ratio of one of the fluoroureides to the diamides, which is a highly specific ranitidine receptor (RyR) modulator insecticide, is from 1:100 to 100:1.

51. A pesticidal mixture according to claim 50, wherein the weight ratio of the novaluron to the tolfenpyrad is from 1:5 to 25:1.

52. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to one of the mesoionic pyrido [1,2- α ] pyrimidinone insecticides is from 1:100 to 100:1.

53. A pesticidal mixture according to claim 52, wherein the weight ratio of the fluoroureide to the pyrithione is 1:1.

54. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to one of the chemical insecticides is from 1:100 to 100:1.

55. A pesticidal mixture according to claim 54, wherein the weight ratio of the novaluron to the fluazinam is 1:1.

56. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the organofluorine insecticide is from 1:100 to 100:1.

57. A pesticidal mixture according to claim 56, wherein the weight ratio of the novaluron to the chlorfenapyr is 1:1.

58. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the pyrrole compound insecticide is from 1:100 to 100:1.

59. A pesticidal mixture according to claim 58, wherein the weight ratio of the fluoroureide to the chlorfenapyr is from 1:10 to 50:1.

60. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the sulfoximine compound insecticide is from 1:100 to 100:1.

61. The pesticidal mixture of claim 60, wherein the weight ratio of the novaluron to the sulfoxaflor is from 1:5 to 100:1.

62. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the fumonic compound insecticide is from 1:100 to 100:1.

63. A pesticidal mixture according to claim 62, wherein the weight ratio of the novaluron to the dinotefuran is 1:1.

64. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the organophosphate compound insecticide is from 1:100 to 100:1.

65. A pesticidal mixture according to claim 64, wherein the weight ratio of the fluoroureide to the acephate is 1:10.

66. A pesticidal mixture according to claim 64, wherein the weight ratio of novaluron to malathion is from 1:1 to 1:10.

67. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the foliar contact insecticide is from 1:100 to 100:1.

68. A pesticidal mixture according to claim 67, wherein the weight ratio of the novaluron to the spiromesifen is from 1:5 to 100:1.

69. The pesticidal mixture of claim 34, wherein the weight ratio of the fluoroureide to the phenylpyrazole chemical compound insecticide is from 1:100 to 100:1.

70. The pesticidal mixture of claim 69, wherein the weight ratio of the novaluron to fipronil is from 1:100 to 100:1.

71. A pesticidal mixture according to claim 34 wherein the weight ratio of the fluoroureide to the other phenylpyrazole insecticides is from 1:100 to 100:1.

72. A pesticidal mixture according to claim 71, wherein the weight ratio of novaluron to tolfenpyrad is from 1:1.

73. A pesticidal composition comprising: (i) The mixture of any one of claims 1-72; and (ii) an agriculturally acceptable carrier.

74. The pesticidal composition of claim 73, further comprising: at least one surfactant, a solid diluent, a liquid diluent, or a combination thereof.

75. A method of reducing the total amount of insecticidal active compound necessary to control unwanted pests by: a) Administering a fluoroureide at an administration rate of from about 25% to about 75% of the recommended administration rate and b) administering at least one active compound II as defined in claim 1.

76. A method for controlling insects, said method comprising contacting said insects or a food supply, habitat, breeding grounds or locus thereof with an effective amount of a mixture of any one of claims 1-72 or a composition of claim 73 or 74 to thereby control insects.

77. A method according to claim 76 for controlling the insect tomato leaf miner by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a bishydrazide insecticide as defined in claim 1 in a ratio from 1:100 to 100:1 to thereby control the insect.

78. A method according to claim 76 for controlling the insect tomato leaf miner by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

79. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a bishydrazide insecticide as defined in claim 1 in a ratio from 1:100 to 100:1 to thereby control the insect.

80. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

81. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and an arylisoxazoline as defined in claim 1, which is one of the gamma-aminobutyric acid (GABA) gated chloride channel allosteric modulator insecticides, in a ratio of from 1:100 to 100:1, to thereby control the insect.

82. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a diamide as defined in claim 1, which is one of the highly specific ranitidine receptor (RyR) modulator insecticides, in a ratio of from 1:100 to 100:1, to thereby control the insect.

83. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the mesoionic pyrido [1,2- α ] pyrimidinone insecticides as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

84. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a chemical insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

85. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and an organofluorine compound as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

86. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a furannicotinoyl compound as defined in claim 1 in a ratio of from 1:100 to 100:1, to thereby control the insect.

87. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

88. The method of claim 76, for controlling insect spodoptera littoralis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

89. A method according to claim 76 for controlling insect frankliniella occidentalis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

90. A method according to claim 76 for controlling insect frankliniella occidentalis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

91. A method according to claim 76 for controlling insect frankliniella occidentalis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

92. The method of claim 76, for controlling Spodoptera frugiperda of Cordyceps sinensis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a spinosad insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

93. The method of claim 76, for controlling Spodoptera frugiperda of Cordyceps sinensis by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a meta-diamide as defined in claim 1, which is one of the GABA-gated chloride channel allosteric modulator insecticides, in a ratio of from 1:100 to 100:1, to thereby control the insect.

94. The method of claim 76, for controlling Spodoptera frugiperda of Cordyceps sinensis by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a diamide as defined in claim 1, which is one of the highly specific ranitidine receptor (RyR) modulator insecticides, in a ratio of from 1:100 to 100:1, to thereby control the insect.

95. The method of claim 76, for controlling insect myzus persicae by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the acetyl-coa carboxylase (ACC) inhibitor insecticides as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

96. The method of claim 76, for controlling insect myzus persicae by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

97. The method of claim 76, for controlling insect myzus persicae by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a foliar contact insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

98. The method of claim 76 for controlling the insect spider mites by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and one of the acetyl-coa carboxylase (ACC) inhibitor insecticides as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

99. The method of claim 76 for controlling the insect spider mites by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a ratio of pyrrole compound insecticides as defined in claim 1 from 1:100 to 100:1 to thereby control the insect.

100. A method according to claim 76 for controlling insect bemisia tabaci by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and a chordal organ TRPV (vanilloid transient receptor potential) channel modulator insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

101. The method of claim 76, for controlling the insect cotton aphid by: contacting the insect or its food supply, habitat, breeding grounds or its locus with an effective amount of a synergistic mixture of a fluoroureide and an organophosphate compound insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

102. The method of claim 76, for controlling the insect cotton aphid by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a foliar contact insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

103. A method according to claim 76 for controlling insect theawing stink bug by: contacting the insect or its food supply, habitat, breeding grounds or locus thereof with an effective amount of a synergistic mixture of a fluoroureide and a phenylpyrazole chemical compound insecticide as defined in claim 1 in a ratio of from 1:100 to 100:1 to thereby control the insect.

104. A method for protecting a plant from attack or infestation by insects, the method comprising contacting the plant, or the soil or water in which the plant is growing, with an effective amount of the mixture of any of claims 1-72 or the composition of claim 73 or 74 to thereby protect the plant from attack or infestation by insects.

105. A method for enhancing knockdown activity and/or elongation control, the method comprising contacting a plant, or soil or water in which the plant is growing, with an effective amount of the mixture of any one of claims 1-72 or the composition of any one of claims 73 or 74, to thereby enhance knockdown activity and/or elongation control.

106. A method for enhancing plant development, the method comprising applying to the plant, locus of the plant and/or propagation material of the plant an effective amount of the mixture of any one of claims 1-72 or the composition of claim 73 or 74 to thereby enhance plant development.

107. A method for regulating plant growth, the method comprising applying to the plant, locus of the plant and/or propagation material of the plant an effective amount of the mixture of any one of claims 1-72 or the composition of claim 73 or 74 to thereby regulate plant growth.