CN103110868B - Skin care solution and preparation method thereof - Google Patents
Skin care solution and preparation method thereof Download PDFInfo
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- CN103110868B CN103110868B CN201310031675.8A CN201310031675A CN103110868B CN 103110868 B CN103110868 B CN 103110868B CN 201310031675 A CN201310031675 A CN 201310031675A CN 103110868 B CN103110868 B CN 103110868B
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Abstract
The invention discloses a skin care solution and a preparation method thereof. The care solution provided by the invention contains Chinese herbal medicinal ingredients with a curing effect on skin, such as leonurus, cortex dictamni, safflower carthamus, radix sophorae flavescentis, radices sileris, Chinese angelica, gallnut, thunder god vine, dark plum and flax seed. The Chinese herbal medicinal ingredients respectively cure the skin by improving blood circulation, adjusting immunity and adjusting in-vivo hormones, so that the skin is lubricated and is elastic, and the health of the skin is ensured. Furthermore, the care solution provided by the invention contains Chinese herbal medicinal ingredients capable of killing various viruses and funguses, such as fructus evodiae, goldthread, cactus, radix stemonae, dandelion, clove and aloe; and the Chinese herbal medicinal ingredients can kill and restrain various germs, the viruses and the funguses on the skin, and ensure that the skin is prevented from invasion and damage of the germs, the viruses and the funguses. The preparation method provided by the invention comprises the following steps of selecting materials, soaking, stewing, purifying and the like, and has the characteristics of simple method, convenience in preparation and low cost.
Description
Technical field
The present invention relates to a kind of conditioning liquid and its preparation method, specifically, relate to a kind of skin care solution and preparation method thereof.
Background technology
Skin is made up of epidermis, corium, subcutaneous tissue three parts.Skin is human body maximum and most important organ, and gross weight accounts for 8% of human body, and the adult skin gross area has 1.5～2.0 square metres.The blood circulation of human body approximately 13% and approximately 14% moisture content in skin, are held.Skin has the physiological functions such as protection, sensation, regulate body temperature, absorption, secretion and excretion, metabolism.Epidermis or corium all play an active part in the activity of removing harmful substance and eliminating invading micro-organism.Skin is the warehouse of health.Corium can be stored a large amount of blood.Subcutaneous tissue can be accumulated significant quantities of fat.So skin is blood bank and energy depot.So, the conditioning liquid of skin be can not be ignored.
In addition, the nursing staff of hospital is more owing to contacting patient in nursing process, so number of times, the kind of its contact antibacterial, fungus, virus are also many, if in nursing process, nursing staff deals with improperly, easily infected.And traditional Medical antiseptic solution mostly is chemical disinfection liquid, larger to medical personnel's skin irritation.Also there are now some to the less Traditional Chinese medicine disinfectant of skin irritation, but the following shortcoming of this class disinfectant solution ubiquity: a little less than sterilizing ability, bactericidal range is little, strong to some vitalitys, infectivity is strong fungus, virus are inoperative, the efficacy of a drug persistent period is short, preparation method complexity, and cost is higher.
Summary of the invention
The technical problem to be solved in the present invention is to overcome above-mentioned defect, and the skin care solution that a kind of bactericidal effect is good, bactericidal range wide, the efficacy of a drug persistent period is long is provided, and the preparation method of the medical skin conditioning liquid that preparation method is simple, cost is low.
For addressing the above problem, the technical solution adopted in the present invention is:
A kind of skin care solution, is characterized in that, described conditioning liquid comprises following component:
Herba Leonuri 10-20 gram, Cortex Dictamni 5-10 gram, Flos Carthami 15-30 gram, Herba Menthae 10-20, Radix Sophorae Flavescentis 10-20 gram, Periostracum Cicadae 6-10 gram, Rhizoma Coptidis 3-5 gram, Fructus Evodiae 10-20 gram, Radix Saposhnikoviae 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 10-20 gram, Galla Chinensis 5-10 gram, Radix Tripterygii Wilfordii 10-20 gram, Radix et Caulis Opuntiae Dillenii 5-15 gram, Fructus Cnidii 5-10 gram, Radix Stemonae 5-10 gram, Fructus Mume 3-8 gram, Semen Lini 5-10 gram, Herba Taraxaci 10-20 gram, Flos Caryophylli 10-20 gram, Aloe 10-20 gram.
Improve as one:
Described conditioning liquid comprises following Chinese medicine component:
15 grams of Herba Leonuris, 8 grams of Cortex Dictamni, 25 grams, Flos Carthami, 15 grams of Herba Menthaes, 15 grams of Radix Sophorae Flavescentiss, 8 grams of Periostracum Cicadaes, 4 grams of Rhizoma Coptidis, 15 grams of Fructus Evodiaes, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Angelicae Sinensis, 15 grams, Radix Glycyrrhizae, 8 grams of Galla Chinensiss, 15 grams of Radix Tripterygii Wilfordiis, 10 grams of Radix et Caulis Opuntiae Dilleniis, 7 grams of Fructus Cnidiis, 7 grams of the Radixs Stemonae, 5 grams of Fructus Mumes, 7 grams of Semen Lini, 15 grams of Herba Taraxacis, 15 grams of Flos Caryophyllis, 15 grams of Aloes.
As further improvement:
Described conditioning liquid comprises following Chinese medicine component:
10 grams of Herba Leonuris, 5 grams of Cortex Dictamni, 15 grams, Flos Carthami, 10 grams of Herba Menthaes, 10 grams of Radix Sophorae Flavescentiss, 6 grams of Periostracum Cicadaes, 3 grams of Rhizoma Coptidis, 10 grams of Fructus Evodiaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Angelicae Sinensis, 10 grams, Radix Glycyrrhizae, 5 grams of Galla Chinensiss, 10 grams of Radix Tripterygii Wilfordiis, 5 grams of Radix et Caulis Opuntiae Dilleniis, 5 grams of Fructus Cnidiis, 5 grams of the Radixs Stemonae, 3 grams of Fructus Mumes, 5 grams of Semen Lini, 10 grams of Herba Taraxacis, 10 grams of Flos Caryophyllis, 10 grams of Aloes.
As further improving:
Described conditioning liquid comprises following Chinese medicine component:
20 grams of Herba Leonuris, 10 grams of Cortex Dictamni, 30 grams, Flos Carthami, 20 grams of Herba Menthaes, 20 grams of Radix Sophorae Flavescentiss, 10 grams of Periostracum Cicadaes, 5 grams of Rhizoma Coptidis, 20 grams of Fructus Evodiaes, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Angelicae Sinensis, 20 grams, Radix Glycyrrhizae, 10 grams of Galla Chinensiss, 20 grams of Radix Tripterygii Wilfordiis, 15 grams of Radix et Caulis Opuntiae Dilleniis, 10 grams of Fructus Cnidiis, 10 grams of the Radixs Stemonae, 8 grams of Fructus Mumes, 10 grams of Semen Lini, 20 grams of Herba Taraxacis, 20 grams of Flos Caryophyllis, 20 grams of Aloes.
Herba Leonuri has promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Effect the present invention of acute nephritis edema mainly utilizes the symptoms such as effect nursing skin acne, freckle, black speck, chloasma of Herba Leonuri blood circulation promoting and blood stasis dispelling.
Cortex Dictamni has heat clearing and damp drying, dispelling wind for relieving itching, the function of removing toxic substances.
Flos Carthami promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.The present invention mainly utilizes the Flos Carthami effect of invigorating blood circulation to strengthen blood circulation and skin metabolism.
Herba Menthae has dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, effect of soothing the liver circulation of qi promoting.Can nurse one's health skin unclean, that block, the sensation that it is refrigerant, can shrink blood capillary, releive itch, inflammation and burning, also can soft skin, also have effect for removing blackhead and oiliness skin quality.Herba Menthae shrinks blood capillary, gets rid of vivotoxin, improve eczema, tinea, releive itch, inflammation and burning, soft skin, eliminates blackhead, is of value to oiliness hair quality and skin quality.
Radix Sophorae Flavescentis is cold in nature, has heat clearing and damp drying, effect of parasite killing, Radix Sophorae Flavescentis is bathed can remove damp-heat in lower-JIAO, and killing parasites for relieving itching, and skin pruritus is had to good mitigation, vegetable Chinese herbal medicine can Bergamot Mint Extract, dredge and restrain pore, removing skin endotoxin impurity, abundant herbal nutrition, promote growth and the reparation of damaged blood vessels neurocyte, recover subcutaneous capillary cell viability, skin reproduction is compacted fine and smooth, plays the effect of beauty and skin care.
Periostracum Cicadae has loose wind heat extraction, sore-throat relieving, rash, nebula removing, effect of spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.The present invention mainly utilizes the effect of Periostracum Cicadae dispelling wind and heat pathogens, often coordinates Herba Menthae to be equal to use for wind heat table disease, rubella pruritus is also had to the function of dispelling wind for relieving itching.
Rhizoma Coptidis has antibacterial action, as staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, dysentery bacterium, anthrax bacillus etc.; Rhizoma Coptidis also has antivirus action, as suppressed influenza virus, hepatitis B virus etc.
Effect of Fructus Evodiae is warming middle-JIAO, cold expelling, the therapeutic method to keep the adverse QI flowing downwards, dissipating depression of QI, has the merit of heat radiation pain relieving, stopping nausea and vomiting by lowering the adverse flow of QI, is used for the treatment of that liver insufficiency of stomach is cold, the disease such as headache or gastralgia due to cloudy turbid superinverse.On clinical practice, trample in recent years, also control enterobiasis by this product, Fructus Evodiae decoct has and kills and inhibitory action pinworm egg.
Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic effect.Radix Saposhnikoviae has the effect of the delayed hypersensitivity due to inhibition DNCB.The skin problem that the present invention mainly utilizes effect combing of the timid wind, relieving exterior syndrome of Radix Saposhnikoviae to have inside to cause suppresses the reflection of part skin allergy simultaneously.
Radix Angelicae Sinensis has anti-hypoxia, regulates body's immunity, anticancer, improves looks, and enriches blood and invigorates blood circulation, the effects such as antibacterial, arteriosclerosis.Modern study finds, Radix Angelicae Sinensis contains multiple organic principle and the trace element such as a large amount of volatile oil, vitamin, organic acid, and experimentation shows, Radix Angelicae Sinensis can be expanded peripheral blood vessel, reduces vascular resistance, increases circulating liquid measure etc.Tryrosinase in human body can produce the melanin that causes freckle, black speck, senile plaque, and its activity is higher, and the appearance of senile plaque is healed early, and quantity is also more.The function of the aqueous solution restraint of tyrosinase activity of Radix Angelicae Sinensis is very strong, thereby the formation of energy check melanin, the pigmented dermatosis such as treatment chloasma, freckle are produced effects well, there is defying age and beautification function, prevent pachylosis, prevent and treat the effects such as acne, chloasma, freckle, without any side effects through observing.
Radix Glycyrrhizae has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer.Radix Glycyrrhizae also has antiinflammatory, and anti-allergic effects can be protected throat and the tunica mucosa tracheae of inflammation.Radix Glycyrrhizae extractum and glycyrrhizic acid have the Detoxication of similar glucuronic acid to some poisonous substance.In Radix Glycyrrhizae, containing glycyrrhizin, is a kind of compound of similar hormone, and it contributes to the hormone-content in balance women body.
Galla Chinensis is astringed the lung, hidroschesis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, hemostasis, effect of removing toxic substances.The present invention mainly utilizes effect of Galla Chinensis removing toxic substances, prevents the infringement to skin such as pathogenic bacteria, toxin.
Radix Tripterygii Wilfordii has effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, reducing swelling and alleviating pain, removing toxic substances parasite killing.Treat lepra reaction, rheumatoid arthritis etc. with it clinically, pharmacological research also shows that it has the effect such as antitumor, antiinflammatory.Radix Tripterygii Wilfordii also has immunoregulation effect, and gas alkaloid can suppress the formation of antibody, is also improved microcirculatory effect, can distend the blood vessels, thereby increase blood flow; The present invention mainly utilizes Radix Tripterygii Wilfordii to suppress abnormal cell hypertrophy, and blood circulation promoting, improves skin environment.
Radix et Caulis Opuntiae Dillenii mainly contains heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, promoting flow of QI and blood, the functions such as benefiting stomach and stopping pain.In addition, Radix et Caulis Opuntiae Dillenii can be removed the thick horny layer of skin, has the effect of skin whitening, and spinoblast fruit has effect of heat-clearing and toxic substances removing.The present invention mainly utilizes Radix et Caulis Opuntiae Dillenii exfoliation function, skin whitening.
Fructus Cnidii has warming the kidney to invigorate YANG, removing dampness and killing parasites, effect of dispelling wind for relieving itching.Can antifungal, arrhythmia, local anaesthesia, antiallergic action, antimutagenic, parasite killing.The present invention mainly utilizes the timid wind of Fructus Cnidii antipruritic and to anaphylactoid inhibitory action replenishing vital QI with drugs of warm nature skin.
The root of the Radix Stemonae is containing multiple alkaloid. and the root of Radix stemonae japonicae contains: (-)-Stemoninine, Stemonidine, isostemonidine, protostermonine, stenine alkali, sinostemonine, these compositions have resisting pathogenic microbes effect, in vitro tests shows: Radix Stemonae decoct and alcohol preserved material are to streptococcus pneumoniae, beta hemolytic streptococcus, meningococcus, staphylococcus aureus, Staphylococcus albus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, diphtheria corynebacterium, pneumobacillus, bacillus pestis, anthrax bacillus, bacillus subtilis and vibrio cholera, Bacillus tuberculosis etc. all have inhibitory action in various degree.Radix stemonae japonicae infusion has certain inhibitory action to some pathomycete in vitro.Radix Stemonae decoct can reduce the pathogenicity of Asia influenza A virus to mice, and the mice having infected is also had to therapeutical effect.
Fructus Mume has protection digestive system, eliminates constipation, appetite stimulator, and anti-aging, purifies the blood, and anemia of pregnant woman's emesis, relieves the effect of alcohol, and increases effect of energy.The present invention mainly utilizes Fructus Mume to remove septicemia element, stimulates the pre-anti-aging of parotid gland hormone secretion, strengthens metabolism.
Semen Lini has the laxation of moisturizing, effect of nourishing the liver and kidney, and for depletion of body fluid causing lack of blood, constipation, body void, the dizzy disease such as weak after being ill.The present invention mainly utilizes Semen Lini to improve by depletion of body fluid causing lack of blood, constipation, the empty problem such as pachylosis, acne causing that waits of body.
Dandelion Injectable Solution has stronger bactericidal action to staphylococcus aureus resistance bacterial strain, Hemolytic streptococcus in vitro, and Diplococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi etc. and micrococcus catarrhalis are also had to certain bactericidal action. and Herba Taraxaci extract (1: 400) can suppress tulase in vitro. and Herba Taraxaci water decoction (1: 80) can delay ECHO11 virocyte pathological changes.Taraxol extract 31mg/kg can kill leptospira.Water logging agent has inhibitory action to various skin fungus.
Emodin, 7-acetyl group-2-methoxyl group-6-methyl-8-hydroxyl-1,4-naphthoquinone in Rhizoma Polygoni Cuspidati have antibacterial activity.Resveratrol In vitro Bactericidal Experiments shows: it has powerful anti-microbial property to the trichophyton rubrum, the trichophyton interdigitalis that cause stubborn dermatitis, pompholyx shape tinea alba, and to bacillus subtilis, Resina garciniae eight repeatedly bacterium etc. have stronger bactericidal action.Emodin, PD, emodin-8-glycoside have inhibitory action to staphylococcus aureus, hepatitis diplococcus.A kind of Flavonoid substances containing in Rhizoma Polygoni Cuspidati has inhibitory action to staphylococcus aureus, Staphylococcus albus, Bacillus proteus.10% Rhizoma Polygoni Cuspidati decocting liquid can II type virus (ECHO11) all have inhibitory action to herpes simplex virus, A type capital, the influenza Asia 68-1 of section virus and dust.3% Rhizoma Polygoni Cuspidati decocting liquid to No. 479 adenovirus type IIIs, No. 72 poliomyelitis II types, No. 44 dusts can 9 types, 7 kinds of representative Strain such as COxsackie A9 type and B5 type, encephalitis B (Jing Wei grinds I strain), No. 140 herpes simplexes all have stronger inhibitory action.Rhizoma Polygoni Cuspidati monomer I and II can make hepatitis B antigen titre reduce by 8 times.
Flos Caryophylli has inhibitory action to the growth of staphylococcus and tubercule bacillus, and lilac water decoct and powder have stronger antibacterial action to Hemolytic streptococcus, its antibacterial action and the impact of not heated.Experimental results show that: the alcohol extract of Flos Caryophylli all has inhibitory action to diphtheria corynebacterium, anthrax bacillus, Salmonella paratyphi, dysentery bacterium, staphylococcus aureus, Staphylococcus albus, vibrio cholera.In vitro tests proves, the alcohol extract of Flos Caryophylli all has inhibitory action to diphtheria corynebacterium, anthrax bacillus, Salmonella paratyphi, dysentery bacterium, staphylococcus aureus, Staphylococcus albus, vibrio cholera.Oleum Caryophylli and eugenol were at 1: 16 000～1:, can stop the growth of Brucella completely at 64000 o'clock; Can suppress the growth of mycobacterium tuberculosis completely at 1: 8 000 o'clock; At 1: 2 000～1: when 8 000 concentration, staphylococcus aureus and pneumobacillus, dysentery bacterium, escherichia coli, Bacillus proteus, tubercule bacillus are all had to inhibitory action. in vitro tests proves, Flos Caryophylli infected by influenza PR8 strain virus has inhibitory action.
Water, alcohol and ether leachate and its volatile oil of Flos Caryophylli, all have obvious antifungic action to pathogenic fungus.Low concentration leachate is had inhibitory action to permitting blue achorion, Candida albicans etc.In vitro, Oleum Caryophylli and eugenol were at 1: 8 000～1: when 16 000 concentration, multiple trichophyton, achorion and epidermophyton inguinale are had to antibacterial action.
Water, alcohol and the ether leachate of Flos Caryophylli have: 1, antibacterial action: the ether leachate of the Flos Caryophylli that contains 1% concentration, infusion or containing the husky Bai Shi culture medium of the Flos Caryophylli decoct of 8% concentration, all has inhibitory action to the multiple pathogenic fungus such as oidium schoenleinii, Candida albicans; When higher concentration, Cryptococcus histolyticus is also had to inhibitory action; Oleum Caryophylli and eugenol are 1: 8000-1:, pathogenic fungus is had to inhibitory action at 16000 o'clock.The bacillus such as staphylococcus aureus and pneumonia, dysentery (will Hayes), large intestine, distortion, tuberculosis are all had to bacteriostasis.Flos Caryophylli infected by influenza PR8 strain also has inhibitory action (in vitro tests).To inhibitory action such as bacillus pestis, vibrio cholera, anthrax bacillus, Bacillus typhi, diphtheria corynebacterium, Bacillus proteus, escherichia coli, bacillus subtilis and staphylococcus aureuses; Oleum Caryophylli and eugenol have inhibitory action to Brucella, and mycobacterium tuberculosis is also had to inhibitory action.2, antifungic action: to star-shaped nocardia, permitted blue achorion, microsporon gypseum and epidermophyton inguinale etc. and have inhibitory action.
Aloe has antiphlogistic antibacterial, strengthens skin elasticity, protects mucocutaneous, pre-anti-acne, prevention freckle and wrinkle, clean skin seborrhea, prevention suppurative dermatosis, moist skin, prevent effect of aging, arresting sweating, perspiration removing.
In the juice that fresh Aloe is squeezed out, contain tinctura aloes (Aloetin), it is the material that antibiotic property is very strong, the pathogenic bacterias such as energy killing fungus, mycete, antibacterial, virus, the growth breeding of inhibition and eliminating pathogen, the pathogenic bacteria class of aloe antibiotic sterilization has: diphtheria bacterium, tetanolysin, pulmonitis strain, lactobacillus, dysentery bacillus, coliform, Bubonic plague bacterium, cholera bacteria and the pathogenic bacteria that causes the diseases such as otitis media, cystitis, pyesis, measles, rabies, poliomyelitis, epidemic encephalitis; The Kallidin I enzyme of Aloe is combined and can be resisted inflammation with vasotonia.Especially the polysaccharide of Aloe can strengthen the resistance of human body to disease, cures the diseases such as dermatitis.
Aloin A, wound hormone and polysaccharide peptide manna (Ke-2) etc. in Aloe juice have viral infection resisting, promote the effect that wound healing restores, and have the function of anti-inflammation and sterilization, clearing heat for detumescence, softening skin, maintenance cell viability.
From above-mentioned explanation, can find out, the Chinese medicine ingredients such as Herba Leonuri in the present invention, Cortex Dictamni, Flos Carthami, Radix Sophorae Flavescentis, Radix Saposhnikoviae, Radix Angelicae Sinensis, Galla Chinensis, Radix Tripterygii Wilfordii, Fructus Mume, Semen Lini mainly play the maintenance action to skin, respectively by improving blood circulation, regulating immunity, control agent internal hormone to carry out maintaining skin, make skin lubrication flexible, ensure the health of skin; Fructus Evodiae in the present invention, Rhizoma Coptidis, Radix et Caulis Opuntiae Dillenii, the Radix Stemonae, Herba Taraxaci, Flos Caryophylli, Aloe have effect of killing multiple virus and fungus, have and kill and inhibitory action being attached to various bacteria, fungus, virus on skin, they have ensured that skin is not subject to infringement and the infringement of antibacterial, fungus, virus; Herba Menthae in the present invention, Periostracum Cicadae, Fructus Cnidii etc. have and change skin quality, the dispelling wind for relieving itching of skin, effect of enhancing skin resistance.And Radix Glycyrrhizae not only can control agent internal hormone, ensure skin health from root, but also be in harmonious proportion many medicines, make farthest performance effect separately of each composition.
As further improving:
A preparation method for medical skin conditioning liquid, is characterized in that, this preparation method comprises the following steps:
A, selection, choose respectively Chinese crude drug according to described weight;
B, immersion, soak 30 minutes after described Chinese crude drug is mixed;
C, decoction, with the first very hot oven decoction of crucible 30 minutes, pour out medicinal liquid, then the slow fire decoction 1 hour that adds water, and filtering medicinal residues, mix medicinal liquid;
D, purification, purify to medicinal liquid by concentrated, centrifugal respectively, gets supernatant;
E, in supernatant, to add concentration be that 80% ethanol, deionized water, glycerol, antiseptic and essence mix homogeneously obtain conditioning liquid.
As further improving:
The weight ratio of described supernatant, ethanol, deionized water, glycerol, antiseptic and essence is 25: 50: 20: 4: 0.3: 0.7.
Described antiseptic is phenoxyethanol.
Wherein, the use of antiseptic phenoxyethanol is non-stimulated to human-body safety, generally be used for pharmaceutically can be used for the anticorrosion preservation of collyrium and injection, easy and other fungicide active ingredients are used in conjunction with, strengthen the activity of other antibacterial, be applicable to pH value scope widely, therefore can be used for multiple formulations type.
Preparation method of the present invention, method is simple, easy to make, and cost is low.
In order further to verify effect of conditioning liquid of the present invention, carry out respectively following test.
Experiment one, sterilization, fungistatic effect experiment.
Choosing respectively ten kinds of pathogenic bacterias is respectively Bacillus typhi, escherichia coli, staphylococcus aureus, tetanolysin, pulmonitis strain, spore exanthema virus, dysentery bacterium, diphtheria corynebacterium, bacillus pestis, tubercule bacillus, these ten kinds of pathogenic bacterias are pathogenic bacterias common in daily life, also be the very exposed to contact pathogenic bacterias of medical personnel, if do not noted at ordinary times, once infected, will bring very major injury to patient.
These ten kinds of pathogenic bacterias are placed in test tube and are cultivated respectively.
Culture environment: temperature, carrier simulation human body palm.
Experiment purpose: the present invention kills and suppress the effect of pathogenic bacteria.
Experimental index: the survival rate of pathogenic bacteria.
Add conditioning liquid of the present invention while enlivening detecting each pathogenic bacteria, respectively one minute, three minutes, detect the survival rate of each pathogenic bacteria when half an hour, one hour, six hours, nine hours and 12 hours, concrete data are as shown in Table 1.
Table one
| Kind/time | One minute | Three minutes | Half an hour | One hour | Six hours | Nine hours | 12 hours |
| Bacillus typhi | 10.5％ | 7.5％ | 0.5％ | 0.20％ | 1.5％ | 2.5％ | 4.4％ |
| Escherichia coli | 9.5％ | 7.5％ | 0.5％ | 0.15％ | 0.8％ | 2.8％ | 3.8％ |
| Staphylococcus aureus | 10.1％ | 8.1％ | 1.1％ | 0.1％ | 1.5％ | 2.5％ | 4.5％ |
| Tetanolysin | 10.2％ | 7.2％ | 1.2％ | 0.2％ | 1.5％ | 3.5％ | 4.5％ |
| Pulmonitis strain | 9.8％ | 7.8％ | 0.8％ | 0.1％ | 1.8％ | 2.8％ | 3.8％ |
| Spore exanthema virus | 9.2％ | 7.2％ | 1.2％ | 0.2％ | 2.2％ | 3.2％ | 4.2％ |
| Dysentery bacterium | 10.5％ | 7.5％ | 1.5％ | 0.25％ | 2.5％ | 3.5％ | 4.3％ |
| Diphtheria corynebacterium | 8.5％ | 6.5％ | 0.5％ | 0.1％ | 1.5％ | 2.5％ | 4.0％ |
| Bacillus pestis | 10.3％ | 7.3％ | 1.3％ | 0.3％ | 1.8％ | 2.0％ | 4.0％ |
| Tubercule bacillus | 8.8％ | 6.8％ | 0.8％ | 0.1％ | 1.5％ | 2.5％ | 4.5％ |
Can find out from table one data, conditioning liquid of the present invention just can kill most of pathogenic bacteria in one minute, after three minutes, just can make the survival rate of pathogenic bacteria be down in 10%, and in the time of half an hour and one hour, pathogenic bacteria is effectively killed and is controlled, survival rate is between 0.1%-1.5%, this illustrates that conditioning liquid bactericidal effect of the present invention is obvious, and, the survival rate recording in the time of nine hours and 12 hours is also lower, in 5%, thus, the ability that conditioning liquid of the present invention suppresses pathogenic bacteria is stronger, in 12 hours, can effectively prevent the infringement of pathogenic bacteria.In addition, conditioning liquid of the present invention all has and significantly kills and inhibitory action these ten kinds of pathogenic bacterias, and bactericidal scope is wide.
Experiment two, skin protection experiment.
Respectively white mice is tested, get 30 white mice, be divided into three groups, every group ten, first group of white mice kind has spore exanthema virus, and second group of white mice is respectively with acne in various degree, the extremity of the 3rd group of white mice have be full of cracks in various degree, and skin is comparatively coarse.Use conditioning liquid of the present invention to clean whole body to first group, second group white mice, every day three times, after three days, the spore rash of first group of white mice is almost recovered, second group of white mice acne disappears, use conditioning liquid of the present invention to clean extremity to the 3rd group of white mice, two days later, the be full of cracks place healing of white mice extremity, skin attenuates, be improved significantly.
Can draw from testing two, conditioning liquid of the present invention is successful aspect skin protection.
Owing to having adopted technique scheme; conditioning liquid of the present invention can not skin protection; and can kill the multiple pathogenic bacteria being attached on skin; and can effectively suppress the survival of pathogenic bacteria, and skin protection, sterilization, fungistatic effect are obvious, and the efficacy of a drug persistent period is long; can effectively protect skin not to be subject to the infringement of pathogenic bacteria; particularly, concerning the medical personnel that are easy to contact with pathogenic bacteria, effect obviously, significant.
Detailed description of the invention
Embodiment 1: a kind of skin care solution, choose following Chinese medicine component: 15 grams of Herba Leonuris, 8 grams of Cortex Dictamni, 25 grams, Flos Carthami, 15 grams of Herba Menthaes, 15 grams of Radix Sophorae Flavescentiss, 8 grams of Periostracum Cicadaes, 4 grams of Rhizoma Coptidis, 15 grams of Fructus Evodiaes, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Angelicae Sinensis, 15 grams, Radix Glycyrrhizae, 8 grams of Galla Chinensiss, 15 grams of Radix Tripterygii Wilfordiis, 10 grams of Radix et Caulis Opuntiae Dilleniis, 7 grams of Fructus Cnidiis, 7 grams of the Radixs Stemonae, 5 grams of Fructus Mumes, 7 grams of Semen Lini, 15 grams of Herba Taraxacis, 15 grams of Flos Caryophyllis, 15 grams of Aloes.
After being mixed, soaks 30 minutes in above-mentioned Chinese medicine, then decoct 30 minutes with the first very hot oven of crucible, taking liquid, the slow fire that adds water again decocts 1 hour, taking liquid, after the medicinal liquid obtaining for twice is mixed, concentrate, centrifugal purification, obtain 200 grams of supernatant, and then add the ethanol that 400 grams of concentration are 80%, 160 grams of deionized waters, 32 grams of glycerol, 2.4 grams of phenoxyethanol, 5.6 grams of essence mix homogeneously to obtain conditioning liquid of the present invention in supernatant.
Embodiment 2: a kind of skin care solution, described conditioning liquid comprises following Chinese medicine component:
10 grams of Herba Leonuris, 5 grams of Cortex Dictamni, 15 grams, Flos Carthami, 10 grams of Herba Menthaes, 10 grams of Radix Sophorae Flavescentiss, 6 grams of Periostracum Cicadaes, 3 grams of Rhizoma Coptidis, 10 grams of Fructus Evodiaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Angelicae Sinensis, 10 grams, Radix Glycyrrhizae, 5 grams of Galla Chinensiss, 10 grams of Radix Tripterygii Wilfordiis, 5 grams of Radix et Caulis Opuntiae Dilleniis, 5 grams of Fructus Cnidiis, 5 grams of the Radixs Stemonae, 3 grams of Fructus Mumes, 5 grams of Semen Lini, 10 grams of Herba Taraxacis, 10 grams of Flos Caryophyllis, 10 grams of Aloes.
After being mixed, soaks 30 minutes in above-mentioned Chinese medicine, then decoct 30 minutes with the first very hot oven of crucible, taking liquid, the slow fire that adds water again decocts 1 hour, taking liquid, after the medicinal liquid obtaining for twice is mixed, concentrate, centrifugal purification, obtain 150 grams of supernatant, and then add the ethanol that 300 grams of concentration are 80%, 120 grams of deionized waters, 24 grams of glycerol, 1.8 grams of phenoxyethanol, 4.2 grams of essence mix homogeneously to obtain conditioning liquid of the present invention in supernatant.
Embodiment 3: a kind of skin care solution, described conditioning liquid comprises following Chinese medicine component:
20 grams of Herba Leonuris, 10 grams of Cortex Dictamni, 30 grams, Flos Carthami, 20 grams of Herba Menthaes, 20 grams of Radix Sophorae Flavescentiss, 10 grams of Periostracum Cicadaes, 5 grams of Rhizoma Coptidis, 20 grams of Fructus Evodiaes, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Angelicae Sinensis, 20 grams, Radix Glycyrrhizae, 10 grams of Galla Chinensiss, 20 grams of Radix Tripterygii Wilfordiis, 15 grams of Radix et Caulis Opuntiae Dilleniis, 10 grams of Fructus Cnidiis, 10 grams of the Radixs Stemonae, 8 grams of Fructus Mumes, 10 grams of Semen Lini, 20 grams of Herba Taraxacis, 20 grams of Flos Caryophyllis, 20 grams of Aloes.
After being mixed, soaks 30 minutes in above-mentioned Chinese medicine, then decoct 30 minutes with the first very hot oven of crucible, taking liquid, the slow fire that adds water again decocts 1 hour, taking liquid, after the medicinal liquid obtaining for twice is mixed, concentrate, centrifugal purification, obtain 250 grams of supernatant, and then add the ethanol that 500 grams of concentration are 80%, 200 grams of deionized waters, 40 grams of glycerol, 3 grams of phenoxyethanol, 7 grams of essence mix homogeneously to obtain conditioning liquid of the present invention in supernatant.
Embodiment 4: a kind of preparation method of skin care solution, this preparation method comprises the following steps:
A, selection, choose respectively Chinese crude drug according to described weight;
B, immersion, soak 30 minutes after described Chinese crude drug is mixed;
C, decoction, with the first very hot oven decoction of crucible 30 minutes, pour out medicinal liquid, then the slow fire decoction 1 hour that adds water, and filtering medicinal residues, mix medicinal liquid;
D, purification, purify to medicinal liquid by concentrated, centrifugal respectively, gets supernatant;
E, in supernatant, to add concentration be 80% ethanol, deionized water, glycerol, phenoxyethanol and essence mix homogeneously, and the weight ratio of described supernatant, ethanol, deionized water, glycerol, phenoxyethanol and essence is 25: 50: 20: obtain conditioning liquid at 4: 0.3: 0.7.
Certainly, in preparation method of the present invention, the kind of antiseptic is more, does not limit and only uses phenoxyethanol as antiseptic, and other medical antiseptic all can.
Claims (7)
1. a skin care solution, is characterized in that, described conditioning liquid comprises following Chinese medicine component:
Herba Leonuri 10-20 gram, Cortex Dictamni 5-10 gram, Flos Carthami 15-30 gram, Herba Menthae 10-20 gram, Radix Sophorae Flavescentis 10-20 gram, Periostracum Cicadae 6-10 gram, Rhizoma Coptidis 3-5 gram, Fructus Evodiae 10-20 gram, Radix Saposhnikoviae 10-20 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 10-20 gram, Galla Chinensis 5-10 gram, Radix Tripterygii Wilfordii 10-20 gram, Radix et Caulis Opuntiae Dillenii 5-15 gram, Fructus Cnidii 5-10 gram, Radix Stemonae 5-10 gram, Fructus Mume 3-8 gram, Semen Lini 5-10 gram, Herba Taraxaci 10-20 gram, Flos Caryophylli 10-20 gram, Aloe 10-20 gram.
2. skin care solution according to claim 1, is characterized in that, described conditioning liquid comprises following Chinese medicine component:
15 grams of Herba Leonuris, 8 grams of Cortex Dictamni, 25 grams, Flos Carthami, 15 grams of Herba Menthaes, 15 grams of Radix Sophorae Flavescentiss, 8 grams of Periostracum Cicadaes, 4 grams of Rhizoma Coptidis, 15 grams of Fructus Evodiaes, 15 grams of Radix Saposhnikoviaes, 15 grams of Radix Angelicae Sinensis, 15 grams, Radix Glycyrrhizae, 8 grams of Galla Chinensiss, 15 grams of Radix Tripterygii Wilfordiis, 10 grams of Radix et Caulis Opuntiae Dilleniis, 7 grams of Fructus Cnidiis, 7 grams of the Radixs Stemonae, 5 grams of Fructus Mumes, 7 grams of Semen Lini, 15 grams of Herba Taraxacis, 15 grams of Flos Caryophyllis, 15 grams of Aloes.
3. skin care solution according to claim 1, is characterized in that, described conditioning liquid comprises following Chinese medicine component:
10 grams of Herba Leonuris, 5 grams of Cortex Dictamni, 15 grams, Flos Carthami, 10 grams of Herba Menthaes, 10 grams of Radix Sophorae Flavescentiss, 6 grams of Periostracum Cicadaes, 3 grams of Rhizoma Coptidis, 10 grams of Fructus Evodiaes, 10 grams of Radix Saposhnikoviaes, 10 grams of Radix Angelicae Sinensis, 10 grams, Radix Glycyrrhizae, 5 grams of Galla Chinensiss, 10 grams of Radix Tripterygii Wilfordiis, 5 grams of Radix et Caulis Opuntiae Dilleniis, 5 grams of Fructus Cnidiis, 5 grams of the Radixs Stemonae, 3 grams of Fructus Mumes, 5 grams of Semen Lini, 10 grams of Herba Taraxacis, 10 grams of Flos Caryophyllis, 10 grams of Aloes.
4. skin care solution according to claim 1, is characterized in that, described conditioning liquid comprises following Chinese medicine component:
20 grams of Herba Leonuris, 10 grams of Cortex Dictamni, 30 grams, Flos Carthami, 20 grams of Herba Menthaes, 20 grams of Radix Sophorae Flavescentiss, 10 grams of Periostracum Cicadaes, 5 grams of Rhizoma Coptidis, 20 grams of Fructus Evodiaes, 20 grams of Radix Saposhnikoviaes, 20 grams of Radix Angelicae Sinensis, 20 grams, Radix Glycyrrhizae, 10 grams of Galla Chinensiss, 20 grams of Radix Tripterygii Wilfordiis, 15 grams of Radix et Caulis Opuntiae Dilleniis, 10 grams of Fructus Cnidiis, 10 grams of the Radixs Stemonae, 8 grams of Fructus Mumes, 10 grams of Semen Lini, 20 grams of Herba Taraxacis, 20 grams of Flos Caryophyllis, 20 grams of Aloes.
5. the preparation method of a kind of skin care solution according to claim 1, is characterized in that, this preparation method comprises the following steps:
A, selection, choose respectively Chinese crude drug according to described weight;
B, immersion, soak 30 minutes after described Chinese crude drug is mixed;
C, decoction, with the first very hot oven decoction of crucible 30 minutes, pour out medicinal liquid, then the slow fire decoction 1 hour that adds water, and filtering medicinal residues, mix medicinal liquid;
D, purification, purify to medicinal liquid by concentrated, centrifugal respectively, gets supernatant;
E, in supernatant, to add concentration be that 80% ethanol, deionized water, glycerol, antiseptic and essence mix homogeneously obtain conditioning liquid.
6. preparation method according to claim 5, is characterized in that, the weight ratio of described supernatant, ethanol, deionized water, glycerol, antiseptic and essence is 25: 50: 20: 4: 0.3: 0.7.
7. according to the preparation method described in claim 5 or 6, it is characterized in that, described antiseptic is phenoxyethanol.
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| CN103417431B (en) * | 2013-07-31 | 2015-05-13 | 郑州高尚生物科技有限公司 | Pharmaceutical composition with whitening action as well as preparation method and application thereof |
| CN103405364B (en) * | 2013-07-31 | 2015-01-14 | 青岛大学 | Traditional Chinese medicine composition with whitening effect, and preparation method and application thereof |
| CN103816089A (en) * | 2014-03-11 | 2014-05-28 | 广州市洋林生物科技开发有限公司 | Skin mucous menbrane antimicrobial fluid and skin mucous menbrane antimicrobial wet tissue |
| CN104208222B (en) * | 2014-08-28 | 2016-09-07 | 广西金秀圣塘山天然保健品有限公司 | Yao nationality's bathing medicine with moisturizing effect and preparation method thereof |
| CN104288074A (en) * | 2014-09-26 | 2015-01-21 | 江苏奇力康皮肤药业有限公司 | Body-moistening shower gel and preparation method thereof |
| CN104856906B (en) * | 2015-05-29 | 2018-02-23 | 广州市科能化妆品科研有限公司 | A kind of anticorrosive composite and its application in cosmetics |
| CN104984263A (en) * | 2015-08-03 | 2015-10-21 | 陈永学 | Skin nursing liquid |
| CN105311170A (en) * | 2015-11-20 | 2016-02-10 | 孙艳 | Pharmaceutical composition for treating pox, acne and dermatitis and preparation method of pharmaceutical composition |
| CN105796378A (en) * | 2016-03-31 | 2016-07-27 | 佛山市芊茹化妆品有限公司 | Acne-removing cosmetic composition |
| CN105943876A (en) * | 2016-06-03 | 2016-09-21 | 山东省文登整骨医院 | Traditional Chinese medicine bacteriostatic cleaning care solution and preparing method and application thereof |
| CN106580791B (en) * | 2016-12-23 | 2020-06-09 | 广州睿森生物科技有限公司 | Antibacterial composition and private care product |
| CN113509526A (en) * | 2021-06-21 | 2021-10-19 | 福建广生健康科技有限公司 | Anti-inflammatory repair composition and preparation method and application thereof |
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| CN1132624A (en) * | 1995-07-10 | 1996-10-09 | 林硕 | Medicatedbath lotion and its prepn |
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