CN102961619A - Traditional Chinese medicine composition for helping children to sleep and preparation method thereof - Google Patents
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Abstract
Description
技术领域 technical field
本发明属于中药领域，具体涉及一种小儿助眠中药组合物及其制备方法。The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for children's sleep aid and a preparation method thereof.
背景技术 Background technique
失眠通常指患者睡眠时经常不易入眠，或睡眠短浅易醒，甚至整夜不能入眠，常以夜间不易入睡或睡而易醒为主要症状的病证。轻者入睡困难，时寐时醒，醒后不能再寐，重者可彻夜不眠。失眠有虚实之分，虚者多属阴虚火旺，心脾两虚，心胆气虚，实者多为肝郁化火、痰热内扰。阴虚火旺型用黄连阿胶汤以滋阴清心，心脾两虚型用归脾汤以补益心脾，心胆气虚型用安神定志丸以益气安神，肝郁化火型用龙胆泻肝汤以疏肝泄热，痰热内扰型用温胆汤以清热化痰。小儿失眠是指有效睡眠量减少，入睡以后真正睡着的时间短于预期的时间。3岁以前的儿童可表现为反对上床、睡眠不专心和中途转醒。6～10岁儿童中表现为入睡困难，而10～13岁儿童多为夜间易醒，并再次入睡困难。Insomnia usually refers to a disease in which the patient is often difficult to fall asleep during sleep, or sleeps short and easy to wake up, or even cannot fall asleep all night. In mild cases, it is difficult to fall asleep, and sometimes wakes up, and can no longer sleep after waking up. In severe cases, it can be sleepless all night. Insomnia can be divided into deficiency and excess. Deficiency patients are mostly yin deficiency and hyperactivity of fire, heart and spleen deficiency, heart and gallbladder qi deficiency, and excess patients are mostly liver depression turning into fire and internal disturbance of phlegm heat. For yin deficiency and hyperactivity of fire type, use Huanglian Ejiao Decoction to nourish yin and clear the heart, for heart and spleen deficiency type, use Guipi Decoction to nourish the heart and spleen, for heart and gallbladder qi deficiency type, use Anshen Dingzhi Pills for nourishing qi and calming the nerves, for liver depression and fire type, use gentian to purify the liver The soup is used to soothe the liver and expel heat, and the Wendan soup is used to clear away heat and resolve phlegm for phlegm-heat internal disturbance type. Insomnia in children means that the amount of effective sleep is reduced, and the time of actually falling asleep after falling asleep is shorter than the expected time. Children before the age of 3 may show objection to going to bed, inattentive sleep, and waking up midway. Children aged 6 to 10 have difficulty falling asleep, while children aged 10 to 13 tend to wake up easily at night and have difficulty falling asleep again.
导致小儿失眠的原因主要有：（1）不良入睡方式：幼儿的入睡困难往往与家长不正确的抚养方法有关，如抱着孩子等其睡着后再放在床上、和儿童一起睡(陪睡)等。（2）睡眠恐怖：幼儿的入睡困难与不安全依恋存在明显关系，4～12岁的儿童对夜晚恐怖，而其父母往往不知道。有的儿童将“睡眠”与“死亡”混为一谈，认为睡着了自己就死了，因而恐惧睡眠。（3）环境因素，睡眠环境中声音嘈杂、灯光太亮、室内过热过冷、湿度太大、床铺不舒适、房间太拥挤，学习压力大等都会影响入睡。The main causes of children’s insomnia are: (1) Bad sleep methods: Children’s difficulty in falling asleep is often related to incorrect parental rearing methods, such as holding the child and waiting for it to fall asleep before putting it on the bed, sleeping with the child (sleeping with the child) )wait. (2) Sleep terror: There is a clear relationship between the difficulty in falling asleep and insecure attachment in young children. Children aged 4-12 are afraid of night, but their parents often don't know it. Some children confuse "sleep" with "death", thinking that they will die when they fall asleep, so they are afraid of sleep. (3) Environmental factors. Noisy sounds in the sleeping environment, too bright lights, too hot and too cold indoors, too much humidity, uncomfortable beds, too crowded rooms, and high study pressure will all affect falling asleep.
小儿失眠的治疗一般不主张给孩子服安眠药，而以调理为主。因此，研究开发服用配伍简单、疗效显著、治愈高的中药制剂对改善睡眠具有重要意义。The treatment of insomnia in children generally does not advocate giving sleeping pills to children, but mainly conditioning. Therefore, it is of great significance to research and develop traditional Chinese medicine preparations with simple compatibility, significant curative effect and high cure rate for improving sleep.
发明内容 Contents of the invention
有鉴于此，本发明的目的在于提供一种疗效肯定、药源充足、效果显著的小儿助眠中药组合物。In view of this, the object of the present invention is to provide a traditional Chinese medicine composition for children's sleep aid with sure curative effect, sufficient drug source and remarkable effect.
为实现本发明的目的，本发明采用如下技术方案：For realizing the purpose of the present invention, the present invention adopts following technical scheme:
一种小儿助眠中药组合物，由如下重量份的原料药制成：A traditional Chinese medicine composition for children's sleep aid, which is made of the following raw materials in parts by weight:
天竺黄90~110份 钩藤190~210份 防风90~110份Tianzhuhuang 90~110 parts Uncaria 190~210 parts Fangfeng 90~110 parts
蝉脱90~110份 淡竹叶290~310份 灯芯90~110份90~110 parts of cicada off 290~310 parts of light bamboo leaves 90~110 parts of wick
绿豆壳390~410份 茯神190~210份 柏子仁190~210份。Mung bean shell 390~410 parts, Fushen 190~210 parts, Baiziren 190~210 parts.
中医古籍记载：“阳气尽，阴气盛，则目瞑；阴气尽，而阳气盛，则寤矣。”这是对睡眠的经典解释，当阳气衰落、阴气上升时，就会引起睡眠。当阳气强盛，阴气变衰弱时，人就会觉醒。此外，睡眠还与肝、心、脾、肺、肾以及它们之间的协同作用密切相关。本发明所述中药组合物针对小儿睡眠不好所形成的主要机制，选用天竺黄、钩藤、防风、蝉脱、淡竹叶、灯芯、绿豆壳、茯神和柏子仁等八味中药材制成，从根本上调节体内阴阳，定惊安神，从而使小儿有一个良好的睡眠。It is recorded in ancient Chinese medicine books: "When Yang Qi is exhausted and Yin Qi is abundant, the eyes will be closed; when Yin Qi is exhausted and Yang Qi is abundant, it will be dull." Can cause sleep. When yang qi becomes strong and yin qi becomes weak, people will awaken. In addition, sleep is also closely related to the liver, heart, spleen, lungs, kidneys and their synergy. The traditional Chinese medicine composition of the present invention aims at the main mechanism of poor sleep in children, and is made from eight flavors of Chinese medicinal materials such as Tianzhu Huang, Uncaria, Fangfeng, Cicada, Bamboo Leaf, Wick, Mung Bean Shell, Fushen and Baiziren. , fundamentally regulate the yin and yang in the body, soothe the nerves, so that children can have a good sleep.
其中，天竺黄，又名竹黄、竹花、竹茧、赤团子，为禾本科植物青皮竹Bambusa textilis McClure或华思劳竹Schizostachyum，chinense Rendle等杆内的分泌液干燥后的块状物。天竺黄性寒，味甘，归肺、肝经，具有化痰止咳、活血祛风、利湿等功效，主要用于咳嗽痰多、百日咳、带下胃痛、风湿痹痛、小儿惊风、跌打损伤等病症。Among them, Tianzhuhuang, also known as bamboo yellow, bamboo flower, bamboo cocoon, red dumpling, is a lump after the exudates in the poles of Gramineae Bambusa textilis McClure or Schizostachyum, chinense Rendle etc. are dried. Tianzhuhuang is cold in nature, sweet in taste, and returns to the lung and liver meridian. It has the functions of reducing phlegm and relieving cough, promoting blood circulation and expelling wind, and promoting dampness. and other diseases.
钩藤，又名大钩丁、双钩藤，为茜草科植物钩藤或华钩藤及其同属多种植物的带钩枝条，攀援状灌木。钩藤性凉，味甘，归、心经，具有清热平肝、熄风止痉等功效，主要用于小儿惊风、夜啼、热盛动风、子痫、肝阳眩晕、肝火头胀痛等病症。Uncaria, also known as Uncaria chinensis and Uncaria double uncaria, is a climbing shrub with hooked branches of Uncaria chinensis or Uncaria chinensis and various plants of the same genus. Uncaria is cool in nature, sweet in taste, and returns to the heart meridian. It has the effects of clearing away heat and calming the liver, extinguishing wind and relieving convulsions, etc. It is mainly used for convulsions in children, night crying, heat and wind, eclampsia, liver yang dizziness, liver fire head pain and other diseases.
防风，又名铜芸、回云、回草、风肉，为伞形科植物防风的根。防风性凉，味甘，归膀胱、肺、脾、肝经，具有祛风解表、胜湿止痛、解痉、止痒等功效，主要用于外感风寒、头痛身痛、风湿痹痛、骨节酸痛、腹痛泄泻、肠风下血、破伤风、风疹瘙痒、疮疡初起等病症。Fangfeng, also known as Tongyun, Huiyun, Huicao, Fengrou, is the root of the Umbelliferae plant Fangfeng. Anti-wind, cool in nature, sweet in taste, belongs to bladder, lung, spleen, and liver meridian, has the functions of dispelling wind and relieving exterior, eliminating dampness, relieving pain, relieving spasm, and relieving itching, etc. Soreness, abdominal pain and diarrhea, intestinal wind and blood, tetanus, rubella itching, early sores and other diseases.
蝉脱（蝉蜕），又名蝉退、蝉衣、知了皮，为蝉的幼虫变成成虫时蜕下的壳。蝉脱性寒，味甘，归肺、肝经，具有散风除热、利咽、透疹、退翳、解痉等功效，主要用于风热感冒、咽痛、音哑、麻疹不透、风疹瘙痒、目赤翳障、惊风抽搐、破伤风等病症。Cicada off (Cicada slough), also known as Cicada Tui, Chanyi, Cicada Pi, is the shell that the larvae of cicadas cast off when they become adults. Cicada is cold in nature, sweet in taste, and returns to the lung and liver meridian. It has the functions of dispelling wind and heat, relieving sore throat, clearing rash, reducing nebula, and relieving spasm. It is mainly used for wind-heat cold, sore throat, hoarseness, and impervious measles. , Rubella itching, convulsions, convulsions, tetanus and other diseases.
淡竹叶，又名碎骨子、山鸡米、迷身草、竹叶卷心，为禾本科多年生草本植物淡竹叶的干燥茎叶。淡竹叶性寒，味甘，归心、肾经，具有甘淡渗利、性寒清降、善导心与小肠之火下行而利尿通淋等功效，主要用于胸中疾热、咳逆上气、吐血、热毒风、止消渴、压丹石毒、消痰、热狂烦闷、中风失音不语、痛头风、止惊悸、瘟疫迷闷、妊妇头旋倒地、小儿惊痈天吊、喉痹、烦热等病症。Bamboo leaves, also known as Broken Bones, Pheasant Rice, Mishen Grass, and Bamboo Leaf Rolls, are the dry stems and leaves of the perennial herb of Gramineae. Bamboo leaves are cold in nature, sweet in taste, return to the heart, kidney meridian, have the effects of sweetness and light penetration, clearing away coldness in nature, good at guiding the fire of the heart and small intestine, diuresis and dredging, etc. It is mainly used for chest fever, coughing, and vomiting blood , Toxic heat wind, quenching thirst, suppressing Danshi poison, eliminating phlegm, mania and depression, apoplexy, aphane, headache, wind, palpitations, plague confusion, pregnant women's head spinning, children's convulsions and carbuncles, Sore throat, dysphoria and other symptoms.
灯芯，又名灯心、灯草、碧玉草、猪矢草，为灯心草科植物灯心草的茎髓或全草。灯芯性微寒，味甘、淡，归心、肺、小肠、膀胱经，具有利水通淋、清心降火等功效，主要用于淋病、水肿、小便不利、尿少涩痛、湿热黄疸、心烦不寐、小儿夜啼、喉痹、口舌生疮、创伤等病症。The wick, also known as the wick, also known as the wick, is the stem marrow or the whole grass of the rush plant of the rush family. The wick is slightly cold in nature, sweet and bland, and returns to the heart, lung, small intestine, and bladder meridian. sleepiness, night crying in children, sore throat, sore tongue, trauma and other diseases.
绿豆壳，又名绿豆皮，为绿豆的种皮。绿豆壳性寒，味甘，无毒，归肺，肝经，具有清热解毒、退翳明目、凉血散瘀等功效，主要用于治外感风热症、肝经风热所致目赤多泪、目生云翳等病症。Mung bean shell, also known as mung bean skin, is the seed coat of mung bean. Mung bean shells are cold in nature, sweet in taste, non-toxic, and return to the lungs and liver meridian. Symptoms such as excessive tears and cloudy eyes.
茯神，又名茯神木，为茯苓菌核中间（白茯苓）抱有松根或细松木心者的部份。茯神性淡，味甘，归心、脾经，具有宁心、安神、利水等功效，主要用于心虚惊悸、健忘、失眠、惊痫、小便不利等病症。Fushen, also known as Fushen wood, is the part of the sclerotia of Poria cocos (White Poria cocos) that holds the pine root or the fine pine wood heart. Poria is mild in nature, sweet in taste, has the effects of returning to the heart and the spleen meridian, and has the effects of calming the mind, calming the nerves, and diuresis.
柏子仁，又名柏子、柏实、侧柏仁，为柏科植物侧柏Biotaorientalis（L.）End1.的种仁。柏子仁性平味甘，归心、肾、大肠经，具有养心安神、润肠通便的功效，主要用于惊悸、失眠、遗精、盗汗、便秘等症。Baiziren, also known as Baizi, Baishi, orientalis, is the seed kernel of Arborvitae Biotaorientalis (L.) End1. Baiziren is flat and sweet in nature, and has the effects of nourishing the heart, calming the nerves, and laxative. It is mainly used for palpitations, insomnia, nocturnal emission, night sweats, and constipation.
本发明中所述的天竺黄、钩藤、防风、蝉脱、淡竹叶、灯芯、绿豆壳、茯神和柏子仁是本领域技术人员公知的，可以通过商业途径从医药商店购买得到或通过现有技术中公开的方法栽培、采收得到，其规格符合国家或行业标准即可。同时所用药材均无毒，长期服用药物依赖性小，且价格低廉，适合普通消费者使用。The geranium, uncaria, windproof, cicada off, light bamboo leaves, wick, mung bean shell, Fushen and Baiziren described in the present invention are well known to those skilled in the art, and can be purchased from pharmaceutical stores through commercial channels or obtained through off-the-shelf It can be cultivated and harvested by the method disclosed in the art, and its specifications can meet the national or industry standards. At the same time, the medicinal materials used are non-toxic, the drug dependence is small after long-term use, and the price is low, which is suitable for ordinary consumers.
作为优选，本发明所述中药组合物，由如下重量份原料制成：As a preference, the traditional Chinese medicine composition of the present invention is made of the following raw materials in parts by weight:
天竺黄100份 钩藤200份 防风100份100 parts of Tianzhuhuang, 200 parts of Uncaria, 100 parts of Fangfeng
蝉脱100份 淡竹叶300份 灯芯100份100 parts of cicada off 300 parts of light bamboo leaves 100 parts of wick
绿豆壳400份 茯神200份 柏子仁200份400 parts of mung bean shell 200 parts of Fushen 200 parts of Baiziren
本发明还提供了所述中药组合物的制备方法，为取90~110重量份天竺黄、190~210重量份钩藤、90~110重量份防风、90~110重量份蝉脱、290~310重量份淡竹叶、90~110重量份灯芯、390~410重量份绿豆壳、190~210重量份茯神和190~210重量份柏子仁共研为粗末混合即得。The present invention also provides a preparation method of the traditional Chinese medicine composition, which is to take 90-110 parts by weight of Tianzhuhuang, 190-210 parts by weight of Uncaria, 90-110 parts by weight of Fangfeng, 90-110 parts by weight of Chantu, 290-310 parts by weight Parts by weight of bamboo leaves, 90-110 parts by weight of wicks, 390-410 parts by weight of mung bean shells, 190-210 parts by weight of Fushen and 190-210 parts by weight of cypress kernels are ground together into coarse powder and mixed.
本发明提供了上述制备方法制备的中药组合物。The invention provides the traditional Chinese medicine composition prepared by the above preparation method.
本发明还提供了所述中药组合物的临床制剂。本领域技术人员可以根据不同患者的需求将本发明所述中药组合物加入制备不同剂型是所需的各种药学上常规的辅料，如崩解剂、润滑剂、乳化剂、粘合剂等，以常规中药制剂方法，经常规加工直接或间接的加入药学上的可接受的辅料制成常用制剂，如片剂、丸剂、胶囊剂、颗粒剂、口服液等。The invention also provides the clinical preparation of the traditional Chinese medicine composition. Those skilled in the art can add the traditional Chinese medicine composition of the present invention according to the needs of different patients and prepare various pharmaceutical conventional adjuvants required for different dosage forms, such as disintegrants, lubricants, emulsifiers, binders, etc. With conventional traditional Chinese medicine preparation methods, conventional processing is directly or indirectly added with pharmaceutically acceptable excipients to make common preparations, such as tablets, pills, capsules, granules, oral liquids, etc.
优选的，本发明所述中药组合物的临床制剂为颗粒剂或口服液，易于小儿使用，顺应性好，疗效明显。Preferably, the clinical preparation of the traditional Chinese medicine composition of the present invention is granule or oral liquid, which is easy for children to use, has good compliance and obvious curative effect.
本发明的药物组合物的使用剂量和使用方法取决于诸多因素，包括患者的年龄、体重、性别、自然健康状况、营养状况、化合物的活性强度、使用时间、代谢速率、病程严重程度以及诊治医师的主观判断。本领域的技术人员根据上述因素可以容易地决定药物组合物的使用剂量和使用方法。The dose and method of use of the pharmaceutical composition of the present invention depend on many factors, including the patient's age, body weight, sex, natural health status, nutritional status, activity intensity of the compound, use time, metabolic rate, severity of the course of the disease, and the treating physician subjective judgment. Those skilled in the art can easily determine the dosage and method of use of the pharmaceutical composition according to the above factors.
本发明还提供了包含本发明所述中药组合物的保健品。The invention also provides health care products comprising the traditional Chinese medicine composition of the invention.
优选的，本发明所述中药组合物的保健品为保健枕。Preferably, the health product of the traditional Chinese medicine composition of the present invention is a health pillow.
本发明还提供了所述保健枕的制备方法，为将本发明所述中药组合物装入制好的布袋中封口，固定于枕芯表面即得。The invention also provides a preparation method of the health-care pillow, which comprises putting the traditional Chinese medicine composition of the invention into a prepared cloth bag, sealing it, and fixing it on the surface of the pillow core.
其中，所述枕芯可以为本领域目前常见的不同材料的填充物，如荞麦壳、谷糠、棉等。Wherein, the pillow core can be filled with different materials commonly used in this field, such as buckwheat husk, rice bran, cotton and the like.
本发明经临床疗效观察，在100例失眠患儿中，服用本发明所述中药组合物口服液10天后，治愈87例，治愈率占87%，好转11例，显效率占11%，总有效率为98%，无效2例，无效率占2%。The present invention is observed through clinical curative effect, among 100 cases of insomnia children, after taking the traditional Chinese medicine composition oral liquid of the present invention for 10 days, 87 cases were cured, the cure rate accounted for 87%, 11 cases took a turn for the better, and the marked rate accounted for 11%. The efficiency was 98%, 2 cases were invalid, and the inefficiency accounted for 2%.
本发明提供了一种小儿助眠中药组合物。本发明所述中药组合物由天竺黄、钩藤、防风、蝉脱、淡竹叶、灯芯、绿豆壳、茯神、柏子仁为原料制备而成，各味中药相互影响，协同作用，定惊、安神、定志，可以对小儿起到很好的安心养神、延长睡眠时间、提高睡眠质量、增强机体免疫力的功效，改善睡眠疗效显著，疗程短、见效快。同时本发明所用药材均无毒，长期使用药物依赖性小，且价格低廉，适合小儿使用，具有广阔的市场前景。The invention provides a traditional Chinese medicine composition for children's sleep aid. The traditional Chinese medicine composition of the present invention is prepared from Tianzhu Huang, Uncaria, Fangfeng, Chantuo, Pale bamboo leaves, wick, mung bean shell, Fushen, and Baiziren. Calming the nerves and calming the mind can play a very good role in reassuring children, prolonging sleep time, improving sleep quality, and enhancing the body's immunity. The effect of improving sleep is significant, and the treatment period is short and quick. At the same time, the medicinal materials used in the present invention are non-toxic, have little dependence on long-term use of the medicine, and are cheap, suitable for use by children, and have broad market prospects.
具体实施方式 Detailed ways
本发明实施例公开了一种小儿定惊安神助眠中药组合物及其制备方法。本领域技术人员可以借鉴本文内容，适当改进工艺参数实现。特别需要指出的是，所有类似的替换和改动对本领域技术人员来说是显而易见的，它们都被视为包括在本发明。本发明的方法已经通过较佳实施例进行了描述，相关人员明显能在不脱离本发明内容、精神和范围内对本文所述的方法进行改动或适当变更与组合，来实现和应用本发明技术。The embodiment of the invention discloses a traditional Chinese medicine composition for calming the nerves and promoting sleep in children and a preparation method thereof. Those skilled in the art can refer to the content of this article to appropriately improve the process parameters to achieve. In particular, it should be pointed out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The method of the present invention has been described through preferred embodiments, and relevant personnel can obviously make changes or appropriate changes and combinations to the method described herein without departing from the content, spirit and scope of the present invention to realize and apply the technology of the present invention .
为了进一步理解本发明，下面结合实施例对本发明提供进行详细说明。In order to further understand the present invention, the present invention will be described in detail below in conjunction with the examples.
实施例1：本发明所述小儿助眠中药组合物Embodiment 1: Children's sleep aid traditional Chinese medicine composition of the present invention
所述中药组合物是由如下原料药制成：天竺黄110g，钩藤190g，防风110g，蝉脱90g，淡竹叶310g，灯芯90g，绿豆壳410g，茯神190g，柏子仁210g。。The traditional Chinese medicine composition is prepared from the following raw materials: 110g of geranium, 190g of Uncaria, 110g of Fangfeng, 90g of cicada, 310g of dandelion leaves, 90g of wick, 410g of mung bean shell, 190g of Fushen, and 210g of Baiziren. .
制备方法为上述药物在常温下按重量配比筛选混合后共研为粗末混合即得。The preparation method is that the above-mentioned medicines are screened and mixed according to the weight ratio at normal temperature, and then co-grinded into coarse powder and mixed.
实施例2：本发明所述小儿助眠中药组合物Embodiment 2: Children's sleep aid traditional Chinese medicine composition of the present invention
所述中药组合物是由如下原料药制成：天竺黄90g，钩藤210g，防风90g，蝉脱110g，淡竹叶290g，灯芯110g，绿豆壳390g，茯神210g，柏子仁190g。The traditional Chinese medicine composition is prepared from the following raw materials: 90g of geranium, 210g of Uncaria, 90g of Fangfeng, 110g of cicada, 290g of dandelion leaves, 110g of wick, 390g of mung bean shell, 210g of Fushen, and 190g of Baiziren.
制备方法为上述药物在常温下按重量配比筛选混合共研为粗末混合即得。The preparation method is that the above-mentioned medicines are screened and mixed according to the weight ratio at normal temperature to be grinded into coarse powder and mixed.
实施例3：本发明所述小儿助眠中药组合物Embodiment 3: Children's sleep aid traditional Chinese medicine composition of the present invention
所述中药组合物是由如下原料药制成：天竺黄100g，钩藤200g，防风100g，蝉脱100g，淡竹叶300g，灯芯100g，绿豆壳400g，茯神200g，柏子仁200g。The traditional Chinese medicine composition is prepared from the following raw materials: 100g of geranium, 200g of Uncaria, 100g of Fangfeng, 100g of cicada, 300g of dandelion leaves, 100g of wick, 400g of mung bean shell, 200g of Fushen, and 200g of Baiziren.
制备方法为上述药物在常温下按重量配比筛选混合后共研为粗末混合即得。The preparation method is that the above-mentioned medicines are screened and mixed according to the weight ratio at normal temperature, and then co-grinded into coarse powder and mixed.
实施例4：本发明所述小儿助眠中药组合物的颗粒剂Embodiment 4: the granule of the children's sleep aid traditional Chinese medicine composition of the present invention
取实施例3所得的中药组合物按常规方法制得本发明所述小儿助眠中药组合物的颗粒剂。The traditional Chinese medicine composition obtained in Example 3 was used to prepare the granules of the children's sleep aid Chinese medicine composition of the present invention according to a conventional method.
实施例5：本发明所述小儿助眠中药组合物的口服液Embodiment 5: The oral liquid of the Chinese medicine composition for children's sleep aid described in the present invention
取实施例3所得的中药组合物按常规方法制得本发明所述小儿助眠中药组合物的口服液。The Chinese medicine composition obtained in Example 3 was used to prepare the oral liquid of the Chinese medicine composition for children's sleep aid of the present invention according to a conventional method.
实施例6：本发明所述小儿助眠保健枕Embodiment 6: Children's sleep aid health pillow according to the present invention
取实施例3得的中药组合物装入制好的布袋中封口，固定在七孔棉枕芯表面即得。每个布袋长50cm、宽30cm，每个布袋装药末200g。Get the Chinese medicine composition that embodiment 3 gets and pack in the cloth bag that makes and seal, be fixed on the surface of seven-hole cotton pillow core to get final product. Each cloth bag is 50cm long and 30cm wide, and each cloth bag is filled with 200g of powdered medicine.
实施例7：本发明所述中药组合物的疗效观察Embodiment 7: the curative effect observation of Chinese medicine composition of the present invention
观察应用本发明所述中药组合物治疗小儿失眠的疗效。Observe the curative effect of applying the traditional Chinese medicine composition described in the present invention to treat infantile insomnia.
选择100例失眠患儿，男49例，女51例，年龄界于2～10岁。Select 100 cases of insomnia children, 49 males and 51 females, aged between 2 and 10 years old.
实施方法：口服本发明实施例5制备的组合物的口服液，每天2瓶，连续使用10天，期间停止其他中西药治疗。Implementation method: Orally take the oral liquid of the composition prepared in Example 5 of the present invention, 2 bottles per day, and use it continuously for 10 days, during which other Chinese and Western medicine treatments are stopped.
疗效观察：本发明在临床上取得了较好的疗效，在100例失眠患儿中，服用本发明所述中药组合物口服液10天后，治愈87例，治愈率占87%，好转11例，显效率占11%，总有效率为98%，无效2例，无效率占2%。Curative effect observation: the present invention has achieved better curative effect clinically, among 100 routine insomnia children, after taking the traditional Chinese medicine composition oral liquid of the present invention for 10 days, 87 cases were cured, the cure rate accounted for 87%, and 11 cases took a turn for the better. The marked rate accounted for 11%, the total effective rate was 98%, 2 cases were ineffective, and the ineffective rate accounted for 2%.
以上实施例的说明只是用于帮助理解本发明的方法及其核心思想。应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以对本发明进行若干改进和修饰，这些改进和修饰也落入本发明权利要求的保护范围内。The descriptions of the above embodiments are only used to help understand the method and core idea of the present invention. It should be pointed out that for those skilled in the art, without departing from the principle of the present invention, some improvements and modifications can be made to the present invention, and these improvements and modifications also fall within the protection scope of the claims of the present invention.
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Application publication date: 20130313 |