CN107271695A - A kind of blood type analytical instrument - Google Patents
A kind of blood type analytical instrument Download PDFInfo
- Publication number
- CN107271695A CN107271695A CN201710507490.8A CN201710507490A CN107271695A CN 107271695 A CN107271695 A CN 107271695A CN 201710507490 A CN201710507490 A CN 201710507490A CN 107271695 A CN107271695 A CN 107271695A
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- column gel
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- gel card
- rotary table
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- 210000004369 blood Anatomy 0.000 title claims abstract description 43
- 239000008280 blood Substances 0.000 title claims abstract description 43
- 230000007246 mechanism Effects 0.000 claims abstract description 107
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 46
- 239000003292 glue Substances 0.000 claims abstract description 38
- 210000003743 erythrocyte Anatomy 0.000 claims description 25
- 238000012360 testing method Methods 0.000 claims description 20
- 239000012267 brine Substances 0.000 claims description 11
- 238000010790 dilution Methods 0.000 claims description 11
- 239000012895 dilution Substances 0.000 claims description 11
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 claims description 11
- 230000005540 biological transmission Effects 0.000 claims description 7
- 238000001816 cooling Methods 0.000 claims description 4
- 239000012774 insulation material Substances 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 239000012266 salt solution Substances 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 claims 1
- 238000002474 experimental method Methods 0.000 abstract description 9
- 230000001112 coagulating effect Effects 0.000 abstract description 3
- 239000000499 gel Substances 0.000 description 51
- UQMRAFJOBWOFNS-UHFFFAOYSA-N butyl 2-(2,4-dichlorophenoxy)acetate Chemical compound CCCCOC(=O)COC1=CC=C(Cl)C=C1Cl UQMRAFJOBWOFNS-UHFFFAOYSA-N 0.000 description 12
- 238000011534 incubation Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000002270 exclusion chromatography Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The present invention relates to a kind of blood type analytical instrument, belong to medical instruments field.The blood type analytical instrument of the present invention collects the micro- glue card of solidifying post not used completely by collecting board, storing bucket is used to collect the complete used solidifying micro- glue card of post, in experiment, if the micro- glue card of solidifying post of whole positions need not be used, the manipulator mechanism of conveying mechanism can take away the micro- glue card of available solidifying post at collecting board, used again, so as to reach the comprehensive utilization to coagulating the micro- glue card of post.In addition, sample charging mechanism and reagent sample storing mechanism are turntable structure, integral utilization space makes blood type analytical instrument compact overall structure, occupied little space.
Description
Technical field
The present invention relates to a kind of blood type analytical instrument, belong to technical field of medical instruments.
Background technology
Immune micro-column gel detection method is state-of-the-art detection method in current serology field, and it is by molecular exclusion chromatography
Principle is detected applied to blood group serology, solves the problems such as mixing blood preparation examination criteria.Compared to traditional slide method
And test tube method, immune micro-column gel detection method have sensitivity it is high, easily standardization, reagent card can normal temperature preservation for a long time etc. it is excellent
Point.Automation blood type analytical instrument is that the instrument commonly used in micro-column gel detection method is immunized, and the instrument has sample-adding, warm bath, blood card
Carrying, mark and puncture, testing result differentiate etc. a series of functions.Wherein in some specific test types, in addition it is also necessary to
The blood type reagent card of sample and reagent will have been added to carry out simulation human body and educated temperature, then centrifuged again and interpretation.It is common micro-
There are 6 experimental sites on post gel cards, because the position used needed for different experiments is different with quantity, therefore many microtrabeculaes
Gel cards are not all used generally completely, and these micro-column gel cards not used completely are generally all simply discarded, and this is to resource
A kind of waste.
The content of the invention
The technical problem to be solved in the present invention is：To overcome above mentioned problem to be carried out there is provided one kind to micro-column gel card
The blood type analytical instrument of comprehensive utilization.
The technical solution adopted for the present invention to solve the technical problems is：
The present invention provides a kind of blood type analytical instrument, including：
Conveying mechanism, micro-column gel card feed mechanism, barcode scanning mechanism, micro-column gel card pricker place plate, sample charging mechanism, examination
Agent sample storing mechanism, centrifugal mechanism, wiper mechanism, collecting board and storage bucket；
The conveying mechanism, including sample charging mechanism and manipulator mechanism, the aspirating needle of sample charging mechanism can be in transmission component
Drive under, place and moved between plate and wiper mechanism in sample charging mechanism, reagent sample storing mechanism, micro-column gel card, machinery
The manipulator of mobile phone structure can capture micro-column gel card and under the drive of transmission component in micro-column gel card feed mechanism, sample-adding
Mechanism, centrifugal mechanism, micro-column gel card are placed transmits micro-column gel card between plate, collecting board and storage bucket；
The micro-column gel card feed mechanism, for placing untapped micro-column gel card；
The barcode scanning mechanism, it is solidifying to microtrabeculae after the manipulator of manipulator mechanism is picked up at micro-column gel card feed mechanism
Glue card carries out barcode scanning；
The micro-column gel card pricker places plate, places position with pricker and micro-column gel card places position, be respectively used to put
Pricker and micro-column gel card are put, manipulator mechanism is picked up at micro-column gel card feed mechanism and microtrabeculae is placed on after micro-column gel card
Gel cards pricker is placed on plate, and manipulator mechanism captures the pricker being placed on micro-column gel card pricker placement plate and punctures microtrabeculae again
Sealing label above gel cards；
The sample charging mechanism, for accommodating micro-column gel card, including, barrel-type casing sets the sample-adding in barrel-type casing to turn
Disk, sample-adding rotating disk can be rotated by sample-adding drive device, if the sample-adding rotating disk tray at the top of sample-adding rotating disk is offered
The dry solidifying micro- glue card of post places position；
The reagent sample storing mechanism is used to store low ionic strength salt solution, normal erythrocytes reagent reservoirs and blood sample
This is simultaneously mixed to three, and the aspirating needle absorption mixed liquor of sample charging mechanism and microtrabeculae positioned at sample charging mechanism is injected into after mixing
In gel cards；
The centrifugal mechanism is centrifuged to the micro- glue card of solidifying post for injecting reagent；
The wiper mechanism is used to clean aspirating needle；
The collecting board is used to collect the micro- glue card of solidifying post not used completely；
The storage bucket is used to collect the complete used solidifying micro- glue card of post.
Preferably, blood type analytical instrument of the invention, the reagent sample storing mechanism, including：
Cylindrical shell；
Lid, lid offers the bar hole stretched into for aspirating needle in circular cylindrical shell body on cylindrical shell；
Cooling assembly, is arranged on cylindrical shell bottom, for be freezed in circular cylindrical shell body；
Outer rotary table component, including, it is arranged on the outer rotary table in circular cylindrical shell body, the outer rotary table driving that driving outer rotary table is rotated
Part, is arranged on the test tube support frame close to cylindrical shell barrel on outer rotary table, is arranged on outer rotary table close to cylindrical shell
The dilution plate with some dilution holes at center；
Inner rotary table component, including, it is arranged on the inner rotary table in circular cylindrical shell body, the inner rotary table driving that driving inner rotary table is rotated
Low ionic strength brine reservoir and some normal erythrocytes reagent reservoirs are provided with part, inner rotary table.
Preferably, annular rack, low ionic strength brine reservoir are provided with blood type analytical instrument of the invention, outer rotary table
And/or some normal erythrocytes reagent reservoirs are placed in the rotating bar on inner rotary table bottom plate, rotating bar can be relative to
Inner rotary table bottom plate is freely rotated, and rotating bar bottom is provided with the gear coordinated with annular rack.
Preferably, on blood type analytical instrument of the invention, inner rotary table on the position corresponding with normal erythrocytes reagent reservoirs
Offer the putting hole for placing normal erythrocytes reagent reservoirs top cover.
Preferably, blood type analytical instrument of the invention, test tube support frame circularizes structure arrangement, with inside and outside two circles, and often
The test tube putting hole of individual test tube support frame offers the barcode scanning groove for passing through barcode scanning light towards cylindrical shell barrel direction.
Preferably, blood type analytical instrument of the invention, the setting height of dilution plate is higher than the height of test tube support frame, with standard
The bottleneck of red blood cell reagent reservoirs is flushed.
Preferably, blood type analytical instrument of the invention, the sample charging mechanism also includes incubating disk, incubates disk and is arranged on sample-adding turn
In the middle of disk, follow sample-adding rotating disk to rotate together with, be provided with the inside of the side wall for incubating disk outside heater block, the side wall of incubation disk
Side has insulation material layer.
Preferably, blood type analytical instrument of the invention, the micro-column gel card pricker, which places pricker placement position on plate, multiple,
Micro-column gel card, which places position, also multiple, and pricker places position into a row, and micro-column gel card places position into a row.
Preferably, blood type analytical instrument of the invention, the centrifugal mechanism is two desk centrifuges.
The beneficial effects of the invention are as follows：The blood type analytical instrument of the present invention, the solidifying post not used completely is collected by collecting board
Micro- glue card, storing bucket is used to collect the complete used solidifying micro- glue card of post, in experiment, if whole positions need not be used
The solidifying micro- glue card of post, the manipulator mechanism of conveying mechanism can take away the micro- glue card of the available solidifying post (position needed for experiment at collecting board
Put the micro- glue card of untapped solidifying post), then used, so as to reach the comprehensive utilization to coagulating the micro- glue card of post.In addition, sample charging mechanism
It is turntable structure with reagent sample storing mechanism, integral utilization space makes blood type analytical instrument compact overall structure, space-consuming
It is small.
Brief description of the drawings
The present invention is further described with reference to the accompanying drawings and examples.
Fig. 1 is a kind of three-dimensional structure diagram of embodiment of blood type analytical instrument of the present invention；
Fig. 2 is the top view of blood type analytical instrument shown in Fig. 1；
Fig. 3 is a kind of three-dimensional structure diagram of embodiment of reagent sample storing mechanism of the present invention.
Reference is：
1- conveying mechanisms；11- manipulator mechanisms；12- sample charging mechanisms；2- micro-column gel card feed mechanisms；3- is loaded machine
Structure；- 4- reagent sample storing mechanisms；40- cylindrical shells；401- cooling assemblies；41- lids；411- bar holes；In 421-
Rotating disk actuator；422- normal erythrocytes reagent reservoirs；423- low ionic strength brine reservoirs；43- outer rotary table components；431- is tried
Pipe support frame；432- dilutes plate；434- outer rotary table actuators；5- centrifugal mechanisms；6- micro-column gel cards place plate；7- cleaning machines
Structure；8- collecting boards；9- stores bucket.
Embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.These accompanying drawings are simplified schematic diagram, only with
Illustration illustrates the basic structure of the present invention, therefore it only shows the composition relevant with the present invention.
Embodiment
The present embodiment provides a kind of blood type analytical instrument, as illustrated in fig. 1 and 2, including
-- conveying mechanism 1, including sample charging mechanism 12 and manipulator mechanism 11, the aspirating needle of sample charging mechanism 12 can be in transmission
Under the drive of component, place and transported between plate 6 and wiper mechanism 7 in sample charging mechanism 3, reagent sample storing mechanism 4, micro-column gel card
Dynamic, the manipulator of manipulator mechanism 11 can capture micro-column gel card and under the drive of transmission component in micro-column gel card feeding
Mechanism 2, sample charging mechanism 3, centrifugal mechanism 5, micro-column gel card are placed transmits micro-column gel between plate 6, collecting board 8 and storage bucket 9
Card；
-- micro-column gel card feed mechanism 2, for placing untapped micro-column gel card；
-- barcode scanning mechanism, it is solidifying to microtrabeculae after the manipulator of manipulator mechanism 11 is picked up at micro-column gel card feed mechanism 2
Glue card carries out barcode scanning；
-- micro-column gel card pricker places plate 6, places position (right positions in figure) with pricker and micro-column gel card is placed
Position (leftward position in figure), is respectively used to place pricker and micro-column gel card, manipulator mechanism 11 is from crawl micro-column gel card
Picked up at material mechanism 2 and micro-column gel card pricker is placed on after barcode scanning and placed on plate 6, manipulator mechanism 11 is captured again to be placed on
The pricker that micro-column gel card pricker is placed on plate 6 punctures the sealing label above micro-column gel card, it is preferable that pricker, which places position, multiple
(be 6 in figure, but be not limited to 6), the different pricker for placing carries out different experiments to puncturing micro-column gel to facilitate
The demand of card, such as, usual micro-column gel card have 6 reagent positions, and the common type of pricker has：Pricker with a needle point,
Pricker with 3 needle points, the pricker with 6 needle points, naturally it is also possible to have other tip positions pricker different with quantity,
Here differ a citing.Micro-column gel card, which places position, also multiple, and pricker places position into a row, and micro-column gel card places position into one
Row.
-- sample charging mechanism 3, with incubation function, including,
Barrel-type casing,
Rotating disk is loaded, is set in barrel-type casing, can be rotated by sample-adding drive device, specifically, be loaded rotating disk
Central shaft passed from barrel-type casing bottom, sample-adding drive device pass through with transmission assembly drive sample-adding rotating disk central shaft turn
It is dynamic；
Disk is incubated, is set in the middle of sample-adding rotating disk, follows sample-adding rotating disk to rotate together with, is provided with the inside of the side wall for incubating disk
Heater block (being preferably silica gel heating device), incubating the outside of the side wall of disk has insulation material layer (foam heat-insulation layer), will
Disk is incubated to separate with sample-adding rotating disk progress heat；
Incubate the incubation disk tray at the top of disk and the sample-adding rotating disk tray at the top of sample-adding rotating disk reflects shape and is disposed with
Some micro- glue cards of solidifying post place position, and incubation disk tray and sample-adding rotating disk tray are contour.
Need the micro- glue card of solidifying post incubated to be placed on incubation disk tray, heating incubation is carried out by heater block, is not required to
What is incubated is placed on sample-adding rotating disk tray, and incubating the outside of the side wall of disk, there is insulation material layer will incubate disk and sample-adding
Rotating disk carries out heat separation, to ensure that the micro- glue card of solidifying post that need not be incubated is not influenceed by heater block.
-- reagent sample storing mechanism 4, for storing low ionic strength salt solution, normal erythrocytes reagent reservoirs and blood sample
This is simultaneously mixed to three, including,
Cylindrical shell 40；
Lid 41, lid offers the bar hole stretched into for aspirating needle in cylindrical shell 40 on cylindrical shell 40
411；
Cooling assembly 401, is arranged on the bottom of cylindrical shell 40, for being freezed for cylindrical shell 40 is interior, preferably
For semiconductor cooler；
Outer rotary table component 43, including, it is arranged on the outer rotary table in cylindrical shell 40, the outer rotary table that driving outer rotary table is rotated
Actuator 434, is arranged on the test tube support frame 431 being circular layout close to the barrel of cylindrical shell 40 on outer rotary table, is arranged on
Close to the dilution plate 432 with some dilution holes being circular layout at the center of cylindrical shell 40 on outer rotary table；Test tube support frame
431 circularize structure arrangement, with inside and outside two circles, and each test tube support frame 431 test tube putting hole towards cylindrical shell
40 barrel directions offer the barcode scanning groove for passing through barcode scanning light, and the setting height of dilution plate 432 is higher than test tube support frame 431
Highly, the bottleneck substantially with normal erythrocytes reagent reservoirs 422 is flushed；
Inner rotary table component 42, including, it is arranged on the inner rotary table in cylindrical shell 40, the inner rotary table that driving inner rotary table is rotated
It is provided with actuator 421, outer rotary table on annular rack, inner rotary table and is provided with low ionic strength brine reservoir 423 (LISS liquid)
With some normal erythrocytes reagent reservoirs 422, low ionic strength brine reservoir 423 and/or some normal erythrocytes reagent reservoirs
422 are placed in the rotating bar on inner rotary table bottom plate, rotating bar can freely be rotated relative to inner rotary table bottom plate (both lead to
Bearing is crossed to fix), rotating bar bottom is provided with the gear coordinated with annular rack, when inner rotary table is rotated, as long as being deposited with outer rotary table
In speed discrepancy, you can make pinion rotation by annular rack, so as to drive low ionic strength brine reservoir 423 and/or some marks
Quasi- red blood cell reagent reservoirs 422 are rotated, namely low ionic strength brine reservoir 423 and/or some normal erythrocytes reagent reservoirs
422 can revolve round the sun also can rotation, store up low ionic strength brine reservoir 423 and/or some normal erythrocytes reagents by rotation
Tank 422 shakes up, and makes agent formulations in low ionic strength brine reservoir 423 and/or some normal erythrocytes reagent reservoirs 422 more
Plus it is uniform；Offered on inner rotary table on the position corresponding with normal erythrocytes reagent reservoirs 422 for placing normal erythrocytes
The putting hole 429 of the top cover of reagent reservoirs 422, the top cover of normal erythrocytes reagent reservoirs 422 can be placed in one-to-one corresponding after backing out
Putting hole 429, lid wrong storage tank when top cover lid is returned can be prevented；The aspirating needle of sample charging mechanism 12 can be respectively from low ionic strength salt
Liquid is drawn on water storage tank 423, normal erythrocytes reagent reservoirs 422 and test tube support frame 431 in test tube and on dilution plate 432
Dilution holes in mixed, liquid is siphoned away and injected in the micro- glue card of solidifying post again after mixing；
The inner rotary table rotating shaft of inner rotary table is passed from the bottom of cylindrical shell 40, passes through tape handler and inner rotary table actuator
421 drive connections, the outer rotary table rotating shaft of outer rotary table is also passed from the bottom of cylindrical shell 40, passes through tape handler and outer rotary table
Actuator 434 is connected, and outer rotary table rotating shaft is set in outside inner rotary table rotating shaft, is consolidated if being provided with dry bearing between the two
It is fixed.
-- centrifugal mechanism 5, the micro- glue card of solidifying post for injecting reagent is centrifuged, preferably 2 desk centrifuges；
-- wiper mechanism 7, for cleaning aspirating needle；
-- collecting board 8, for collecting the micro- glue card of solidifying post not used completely, deposited because the solidifying micro- glue cartoon of post often has 6
Storage space is put, when doing blood group experiment, may only use part storage location therein, in order to save, and will can not used completely
The solidifying micro- glue card of post is collected, when only needing to use unused portion to coagulate the experiment of the micro- glue card of post, is reused this part and is coagulated
The micro- glue card of post, economizes on resources；
-- bucket 9 is stored, for collecting the complete used solidifying micro- glue card of post.
Step flow when the blood type analytical instrument of the present embodiment carries out blood type analysis is：Scan-puncturing-and be loaded-(temperature
Educate)-centrifugation-acquisition image-automatic decision result, present invention point is hardware components, software section omit without
Repeat.The blood type analytical instrument of the present embodiment, the micro- glue card of the solidifying post not used completely is collected by collecting board 8, and storing bucket 9 is used to receive
The collection used solidifying micro- glue card of post completely, in experiment, if the micro- glue card of solidifying post of whole positions, conveying mechanism need not be used
1 manipulator mechanism 11 can be taken away at collecting board 8 the micro- glue card of available solidifying post (experiment the untapped solidifying post in desired position
Micro- glue card), then used, so as to reach the comprehensive utilization to coagulating the micro- glue card of post.In addition, in the present embodiment, the He of sample charging mechanism 3
Reagent sample storing mechanism 4 is turntable structure, and integral utilization space makes blood type analytical instrument compact overall structure, space-consuming
It is small.
Using the above-mentioned desirable embodiment according to the present invention as enlightenment, by above-mentioned description, relevant staff is complete
Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention
Property scope is not limited to the content on specification, it is necessary to its technical scope is determined according to right.
Claims (9)
1. a kind of blood type analytical instrument, it is characterised in that including：
Conveying mechanism (1), micro-column gel card feed mechanism (2), barcode scanning mechanism, micro-column gel card pricker place plate (6), sample-adding machine
Structure (3), reagent sample storing mechanism (4), centrifugal mechanism (5), wiper mechanism (7), collecting board (8) and storage bucket (9)；
The conveying mechanism (1), including sample charging mechanism (12) and manipulator mechanism (11), the aspirating needle of sample charging mechanism (12) can
Under the drive of transmission component, plate (6) is placed and clear in sample charging mechanism (3), reagent sample storing mechanism (4), micro-column gel card
Moved between washing machine structure (7), the manipulator of manipulator mechanism (11) can capture micro-column gel card and in the drive of transmission component
Under micro-column gel card feed mechanism (2), sample charging mechanism (3), centrifugal mechanism (5), micro-column gel card place plate (6), collecting board
(8) micro-column gel card is transmitted between storage bucket (9)；
The micro-column gel card feed mechanism (2), for placing untapped micro-column gel card；
The barcode scanning mechanism, after the manipulator of manipulator mechanism (11) is picked up from micro-column gel card feed mechanism (2), to microtrabeculae
Gel cards carry out barcode scanning；
The micro-column gel card pricker places plate (6), places position with pricker and micro-column gel card places position, be respectively used to place
Pricker and micro-column gel card, manipulator mechanism (11) are picked up from micro-column gel card feed mechanism (2) and placed after micro-column gel card
Placed in micro-column gel card pricker on plate (6), manipulator mechanism (11) is captured again is placed on micro-column gel card pricker placement plate (6)
On pricker puncture sealing label above micro-column gel card；
The sample charging mechanism (3), for accommodating micro-column gel card, including, barrel-type casing sets the sample-adding in barrel-type casing to turn
Disk, sample-adding rotating disk can be rotated by sample-adding drive device, if the sample-adding rotating disk tray at the top of sample-adding rotating disk is offered
The dry solidifying micro- glue card of post places position；
The reagent sample storing mechanism (4) is used to store low ionic strength salt solution, normal erythrocytes reagent reservoirs and blood sample
This is simultaneously mixed to three, and the aspirating needle of sample charging mechanism (12) is drawn mixed liquor and is injected into positioned at sample charging mechanism after mixing
(3) in micro-column gel card；
The centrifugal mechanism (5) centrifuges to the micro- glue card of solidifying post for injecting reagent；
The wiper mechanism (7) is used to clean aspirating needle；
The collecting board (8) is used to collect the micro- glue card of solidifying post not used completely；
The storage bucket (9) is used to collect the complete used solidifying micro- glue card of post.
2. blood type analytical instrument according to claim 1, it is characterised in that the reagent sample storing mechanism (4), including：
Cylindrical shell (40)；
Lid (41), lid offers the bar shaped stretched into for aspirating needle in cylindrical shell (40) on cylindrical shell (40)
Hole (411)；
Cooling assembly (401), is arranged on cylindrical shell (40) bottom, for being freezed for cylindrical shell (40) is interior；
Outer rotary table component (43), including, it is arranged on the outer rotary table in cylindrical shell (40), the outer rotary table that driving outer rotary table is rotated
Actuator (434), is arranged on the test tube support frame (431) close to cylindrical shell (40) barrel on outer rotary table, and setting turns outside
Close to the dilution plate (432) with some dilution holes at cylindrical shell (40) center on disk；
Inner rotary table component (42), including, it is arranged on the inner rotary table in cylindrical shell (40), the inner rotary table that driving inner rotary table is rotated
Low ionic strength brine reservoir (423) and some normal erythrocytes reagent reservoirs are provided with actuator (421), inner rotary table
(422)。
3. blood type analytical instrument according to claim 2, it is characterised in that annular rack, low ion are provided with outer rotary table
Intensity brine reservoir (423) and/or some normal erythrocytes reagent reservoirs (422) are placed at turning on inner rotary table bottom plate
In lever, rotating bar can freely be rotated relative to inner rotary table bottom plate, and rotating bar bottom is provided with the gear coordinated with annular rack.
4. the blood type analytical instrument according to Claims 2 or 3, it is characterised in that stored up on inner rotary table with normal erythrocytes reagent
The putting hole (429) for placing normal erythrocytes reagent reservoirs (422) top cover is offered on the corresponding position of tank (422).
5. the blood type analytical instrument according to claim any one of 1-4, it is characterised in that test tube support frame (431) is circularized
Structure arranges, with inside and outside two circles, and each test tube support frame (431) test tube putting hole towards cylindrical shell (40) barrel
Direction offers the barcode scanning groove for passing through barcode scanning light.
6. blood type analytical instrument according to claim 5, it is characterised in that the setting of dilution plate (432) is highly higher than test tube
The height of support frame (431), is flushed with the bottleneck of normal erythrocytes reagent reservoirs (422).
7. the blood type analytical instrument according to claim any one of 1-6, it is characterised in that the sample charging mechanism (3) also includes
Disk is incubated, disk is incubated and is arranged in the middle of sample-adding rotating disk, follow sample-adding rotating disk to rotate together with, be provided with the inside of the side wall for incubating disk
Heater block, incubating the outside of the side wall of disk has insulation material layer.
8. the blood type analytical instrument according to claim any one of 1-7, it is characterised in that the micro-column gel card pricker is placed
Pricker, which places position, on plate (6) multiple, and micro-column gel card, which places position, also multiple, and pricker places position into a row, micro-column gel card
Position is placed into a row.
9. the blood type analytical instrument according to claim any one of 1-8, it is characterised in that the centrifugal mechanism (5) is two
Centrifuge.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710507490.8A CN107271695B (en) | 2017-06-28 | 2017-06-28 | A kind of blood type analytical instrument |
| PCT/CN2017/106255 WO2019000708A1 (en) | 2017-06-28 | 2017-10-16 | Blood type analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710507490.8A CN107271695B (en) | 2017-06-28 | 2017-06-28 | A kind of blood type analytical instrument |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107271695A true CN107271695A (en) | 2017-10-20 |
| CN107271695B CN107271695B (en) | 2018-10-16 |
Family
ID=60070367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710507490.8A Active CN107271695B (en) | 2017-06-28 | 2017-06-28 | A kind of blood type analytical instrument |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108772209A (en) * | 2018-08-14 | 2018-11-09 | 徐州市儿童医院 | Constant temperature blood group centrifuge |
| WO2022000814A1 (en) * | 2020-06-29 | 2022-01-06 | 苏州长光华医生物医学工程有限公司 | Inner-outer ring incubation tray device having auxiliary sample loading positions, and incubation method |
| CN113970626A (en) * | 2021-09-30 | 2022-01-25 | 武汉新烽光电股份有限公司 | Water quality detection equipment and detection method |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020155516A1 (en) * | 2001-04-24 | 2002-10-24 | Dade Behring Inc. | Method for minimizing optical interference during antibiotic susceptibility readings in a microbiological analyzer |
| CN101275965A (en) * | 2007-03-29 | 2008-10-01 | 希森美康株式会社 | Specimen Analyzer and Reagent Pipetting Method |
| CN102707074A (en) * | 2012-06-07 | 2012-10-03 | 北京金豪制药股份有限公司 | ABO/RhD blood typing detection reagent card and preparation thereof |
| CN104360089A (en) * | 2014-11-05 | 2015-02-18 | 合肥天一生物技术研究所 | Full-automatic microcolumn gel card detection instrument |
| CN104730268A (en) * | 2013-12-24 | 2015-06-24 | 广州万孚生物技术股份有限公司 | Method and device for detecting liquid samples |
| CN106596992A (en) * | 2017-02-15 | 2017-04-26 | 山东新华医疗器械股份有限公司 | Multi-channel fully automatic blood type analyzer |
-
2017
- 2017-06-28 CN CN201710507490.8A patent/CN107271695B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020155516A1 (en) * | 2001-04-24 | 2002-10-24 | Dade Behring Inc. | Method for minimizing optical interference during antibiotic susceptibility readings in a microbiological analyzer |
| CN101275965A (en) * | 2007-03-29 | 2008-10-01 | 希森美康株式会社 | Specimen Analyzer and Reagent Pipetting Method |
| CN102707074A (en) * | 2012-06-07 | 2012-10-03 | 北京金豪制药股份有限公司 | ABO/RhD blood typing detection reagent card and preparation thereof |
| CN104730268A (en) * | 2013-12-24 | 2015-06-24 | 广州万孚生物技术股份有限公司 | Method and device for detecting liquid samples |
| CN104360089A (en) * | 2014-11-05 | 2015-02-18 | 合肥天一生物技术研究所 | Full-automatic microcolumn gel card detection instrument |
| CN106596992A (en) * | 2017-02-15 | 2017-04-26 | 山东新华医疗器械股份有限公司 | Multi-channel fully automatic blood type analyzer |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108772209A (en) * | 2018-08-14 | 2018-11-09 | 徐州市儿童医院 | Constant temperature blood group centrifuge |
| WO2022000814A1 (en) * | 2020-06-29 | 2022-01-06 | 苏州长光华医生物医学工程有限公司 | Inner-outer ring incubation tray device having auxiliary sample loading positions, and incubation method |
| CN113970626A (en) * | 2021-09-30 | 2022-01-25 | 武汉新烽光电股份有限公司 | Water quality detection equipment and detection method |
| CN113970626B (en) * | 2021-09-30 | 2024-04-02 | 武汉新烽光电股份有限公司 | Water quality detection equipment and detection method |
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|---|---|
| CN107271695B (en) | 2018-10-16 |
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