CN105248421B - A kind of composition pesticide containing Spiromesifen and bishydrazide - Google Patents
A kind of composition pesticide containing Spiromesifen and bishydrazide Download PDFInfo
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- CN105248421B CN105248421B CN201510681196.XA CN201510681196A CN105248421B CN 105248421 B CN105248421 B CN 105248421B CN 201510681196 A CN201510681196 A CN 201510681196A CN 105248421 B CN105248421 B CN 105248421B
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- CN
- China
- Prior art keywords
- spiromesifen
- tebufenozide
- active component
- luo
- bishydrazide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 title claims abstract description 98
- 239000005665 Spiromesifen Substances 0.000 title claims abstract description 96
- 239000000203 mixture Substances 0.000 title claims abstract description 52
- 239000000575 pesticide Substances 0.000 title claims abstract description 34
- 239000005937 Tebufenozide Substances 0.000 claims abstract description 79
- QYPNKSZPJQQLRK-UHFFFAOYSA-N tebufenozide Chemical compound C1=CC(CC)=CC=C1C(=O)NN(C(C)(C)C)C(=O)C1=CC(C)=CC(C)=C1 QYPNKSZPJQQLRK-UHFFFAOYSA-N 0.000 claims abstract description 78
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims abstract description 63
- 239000000460 chlorine Substances 0.000 claims abstract description 35
- 229910052801 chlorine Inorganic materials 0.000 claims abstract description 35
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims abstract description 34
- 241000238631 Hexapoda Species 0.000 claims abstract description 34
- 239000000375 suspending agent Substances 0.000 claims description 23
- 230000000694 effects Effects 0.000 claims description 15
- 239000003094 microcapsule Substances 0.000 claims description 13
- 241000256247 Spodoptera exigua Species 0.000 claims description 12
- 239000000839 emulsion Substances 0.000 claims description 12
- 241000426497 Chilo suppressalis Species 0.000 claims description 11
- 241000255967 Helicoverpa zea Species 0.000 claims description 11
- 241000255969 Pieris brassicae Species 0.000 claims description 9
- 241000500437 Plutella xylostella Species 0.000 claims description 9
- 241000018137 Trialeurodes vaporariorum Species 0.000 claims description 8
- 229920000742 Cotton Polymers 0.000 claims description 7
- 241000985245 Spodoptera litura Species 0.000 claims description 7
- 239000000725 suspension Substances 0.000 claims description 7
- 241000258937 Hemiptera Species 0.000 claims description 6
- 241000488583 Panonychus ulmi Species 0.000 claims description 6
- 239000004530 micro-emulsion Substances 0.000 claims description 6
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 239000004563 wettable powder Substances 0.000 claims description 6
- 241001124076 Aphididae Species 0.000 claims description 5
- 241001491790 Bupalus piniaria Species 0.000 claims description 5
- 241000289763 Dasygaster padockina Species 0.000 claims description 5
- 241001046947 Ectropis obliqua Species 0.000 claims description 5
- 241001477931 Mythimna unipuncta Species 0.000 claims description 5
- 241000346285 Ostrinia furnacalis Species 0.000 claims description 5
- 241000255901 Tortricidae Species 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 2
- 241000219146 Gossypium Species 0.000 claims description 2
- 244000144730 Amygdalus persica Species 0.000 claims 1
- 241000002163 Mesapamea fractilinea Species 0.000 claims 1
- 235000006040 Prunus persica var persica Nutrition 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 27
- 241000607479 Yersinia pestis Species 0.000 abstract description 25
- 230000002195 synergetic effect Effects 0.000 abstract description 22
- 239000005917 Methoxyfenozide Substances 0.000 abstract description 18
- QCAWEPFNJXQPAN-UHFFFAOYSA-N methoxyfenozide Chemical compound COC1=CC=CC(C(=O)NN(C(=O)C=2C=C(C)C=C(C)C=2)C(C)(C)C)=C1C QCAWEPFNJXQPAN-UHFFFAOYSA-N 0.000 abstract description 17
- 150000001875 compounds Chemical class 0.000 abstract description 13
- 229940079593 drug Drugs 0.000 abstract description 10
- 239000003905 agrochemical Substances 0.000 abstract description 4
- 230000009471 action Effects 0.000 abstract description 3
- 238000012271 agricultural production Methods 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 238000003912 environmental pollution Methods 0.000 abstract description 2
- 244000144977 poultry Species 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 40
- 230000003449 preventive effect Effects 0.000 description 30
- 238000013329 compounding Methods 0.000 description 28
- 239000003795 chemical substances by application Substances 0.000 description 15
- 239000012071 phase Substances 0.000 description 15
- 239000013530 defoamer Substances 0.000 description 13
- 239000002270 dispersing agent Substances 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- 238000002474 experimental method Methods 0.000 description 12
- 241001198505 Anarsia lineatella Species 0.000 description 11
- 239000008367 deionised water Substances 0.000 description 10
- 229910021641 deionized water Inorganic materials 0.000 description 10
- 239000003995 emulsifying agent Substances 0.000 description 10
- 239000002904 solvent Substances 0.000 description 9
- 241001454293 Tetranychus urticae Species 0.000 description 8
- 230000002528 anti-freeze Effects 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 8
- 235000013311 vegetables Nutrition 0.000 description 8
- 239000000080 wetting agent Substances 0.000 description 8
- 206010067482 No adverse event Diseases 0.000 description 7
- 150000002148 esters Chemical class 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 231100000820 toxicity test Toxicity 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 239000008346 aqueous phase Substances 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000013401 experimental design Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 206010011732 Cyst Diseases 0.000 description 4
- 241000227653 Lycopersicon Species 0.000 description 4
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 4
- 230000010165 autogamy Effects 0.000 description 4
- 208000031513 cyst Diseases 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 229920002521 macromolecule Polymers 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000003002 pH adjusting agent Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 239000011149 active material Substances 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000007884 disintegrant Substances 0.000 description 3
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 108010057988 ecdysone receptor Proteins 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000003630 growth substance Substances 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 241000239290 Araneae Species 0.000 description 1
- 241000254127 Bemisia tabaci Species 0.000 description 1
- 235000016068 Berberis vulgaris Nutrition 0.000 description 1
- 241000335053 Beta vulgaris Species 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 241001674939 Caulanthus Species 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 239000005887 Chromafenozide Substances 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000721714 Macrosiphum euphorbiae Species 0.000 description 1
- 241000256259 Noctuidae Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000893966 Trichophyton verrucosum Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000007798 antifreeze agent Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- HPNSNYBUADCFDR-UHFFFAOYSA-N chromafenozide Chemical compound CC1=CC(C)=CC(C(=O)N(NC(=O)C=2C(=C3CCCOC3=CC=2)C)C(C)(C)C)=C1 HPNSNYBUADCFDR-UHFFFAOYSA-N 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000032669 eclosion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009313 farming Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 150000002240 furans Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 239000000833 heterodimer Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 230000001418 larval effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 235000021110 pickles Nutrition 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000004894 snout Anatomy 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of composition pesticide containing Spiromesifen and bishydrazide, the composition pesticide containing active components A Yu active component B, active components A is selected from Spiromesifen, and active component B is selected from any one following compound：Tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide, and active components A and active component B weight ratio are the ︰ 1 of 1 ︰ 60~80.The present composition has synergistic effect to the various pests for endangering agricultural production, reduces pesticide usage amount, reduces residual quantity of the agricultural chemicals on crop, alleviate environmental pollution, to person poultry safety, Environmental compatibility is good, and insect is not likely to produce the resistance to the action of a drug.
Description
The application is divisional application, and original application is a kind of patent application " mite of first containing spiral shell of Shaanxi Meibang Pesticide Co., Ltd.
The composition pesticide of ester and bishydrazide ", the application Wei ︰ 201210310713.9 of original application, original application day is
2012.08.29。
Technical field
The invention belongs to technical field of pesticide, it is related to a kind of composition pesticide containing Spiromesifen and bishydrazide in farming
Application on thing insect.
Background technology
Spiromesifen (Spiromesifen) molecular formula：C23H30O4.The mechanism of action of Spiromesifen is influence aleyrodid and mite
The development of worm, disturbs the biosynthesis of its liposome, especially there is preferable activity to larval stage, while ovary can also be produced
The fertility of pipe closure function, reduction acarid and adult whitefly, greatly reduces spawning quantity.
Tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide belong to bishydrazide insect growth
Conditioning agent.Bishydrazide insect growth regulator, IGR is that the class developed successively in recent years is efficient, selective strong, environment amenable
Insect growth regulator, IGR, its action target equally, is incorporated into ecdysone receptor (EcR)-mistake with insect moulting hormones (20E)
The heterodimer of surplus valve albumen (USP), induces the transcription of insect early gene, but because bishydrazide compounds are in insect
Internal lasting presence, prevents the event that 20E occurs in the case of being not present from carrying out, such as DOP Adecarboxylase (DDC) is isogenic
Expression is obstructed, and does not synthesize chitin, and eclosion hormo can not discharge, finally make larva precocity decortication and it is dead.
However, in the real process of agricultural production, pest control is easiest to generate the problem that the production of pest resistance to insecticide
It is raw.Different cultivars composition is compounded, and is to prevent and treat resistant insect very common method.Heterogeneity is compounded, according to reality
Application effect, to judge that certain compounding is synergy plus and or antagonism.In most cases, the compounding effect of agricultural chemicals
All be additive effect, really there is synergy to lack, especially synergistic effect clearly, co-toxicity coefficient very high compounding it is just less
.Study very much, found Spiromesifen and tebufenozide, methoxyfenozide, furan tebufenozide, ring worm by the compounding of inventor
Can produce good synergistic effect after hydrazides, chlorine tebufenozide compounding, and on Spiromesifen and tebufenozide, methoxyfenozide,
Furan tebufenozide, ring tebufenozide, the relevant report of chlorine tebufenozide compounding are not yet disclosed.
The content of the invention
The purpose of the present invention is to propose to synergistic function, use cost be low, preventive effect is good containing Spiromesifen with it is double
The composition pesticide of hydrazides class.
A kind of composition pesticide containing Spiromesifen and bishydrazide, contains active components A and active component B, its feature
It is：Active components A and active component B weight ratio are the ︰ 1 of 1 ︰ 60~80, and described active components A is selected from Spiromesifen, living
Property composition B be selected from one of tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide and plant, active components A with
Weight ratio preferred active component B is the ︰ 1 of 1 ︰ 40~60, and more preferably the weight ratio of Spiromesifen and tebufenozide is the ︰ of 1 ︰ 25~10
1, the weight ratio of Spiromesifen and methoxyfenozide is the ︰ 1 of 1 ︰ 15~30, and the weight ratio of Spiromesifen and furan tebufenozide is 1 ︰ 20
The weight ratio of~20 ︰ 1, Spiromesifen and ring tebufenozide is the ︰ 1 of 1 ︰ 15~30, and the weight ratio of Spiromesifen and chlorine tebufenozide is 1 ︰
10~30 ︰ 1；Most preferably the weight ratio of Spiromesifen and tebufenozide is the ︰ 1 of 1 ︰ 15~5, Spiromesifen and methoxyfenozide weight
Amount is than being the ︰ 1 of 1 ︰ 5~10, and the weight ratio of Spiromesifen and furan tebufenozide is the ︰ 1 of 1 ︰ 10~10, Spiromesifen and ring tebufenozide
Weight ratio is the ︰ 1 of 1 ︰ 5~10, and the weight ratio of Spiromesifen and chlorine tebufenozide is the ︰ 1 of 1 ︰ 5~15.
The described composition pesticide containing Spiromesifen and bishydrazide is used for the application for preventing and treating crop pests, described
Crops include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop,
Have a liking for crop, root crop, oil crops, flower crop, medicinal crop, crop, green manure pasture crop；Described evil
Worm includes whitefly in bt cotton, Tetranychus urticae, red spider, leaf roller, beet armyworm, prodenia litura, diamondback moth, tea geometrid, corn borer, two
Change snout moth's larva, armyworm, pine moth, aphid, trialeurodes vaporariorum, small heart-eating peach worm, bollworm, cutworm, cabbage caterpillar.
Active components A, active component B weight ratio are the ︰ 1 of 1 ︰ 60~80.The weight hundred of active component in usual composition
It is the 0.5%~90% of gross weight, preferably 5%~80% to divide content.According to different preparation types, active component content
Scope is different.Generally, liquid preparation contains by weight 1%~70% active material, preferably 5%~50%；
Solid pharmaceutical preparation contains by weight 5%~80% active material, preferably 10%~80%.
At least contain a kind of surfactant in the composition pesticide of the present invention, active component is in water during in favor of applying
It is scattered.Surface-active contents are the 5%~30% of total formulation weight, and surplus is solid or liquid diluent.
The present invention composition pesticide can by user using it is preceding through dilute or directly use.Its preparation can be by usual
Processing method known in those skilled in the art prepare, i.e., after active material is mixed with liquid flux or solid carrier,
The one kind added in surfactant such as dispersant, stabilizer, wetting agent, binding agent, defoamer, disintegrant, antifreeze
Or it is several.
The composition pesticide of the present invention, acceptable formulation on any agricultural chemicals can be processed on demand, wherein more excellent dose
Type is：Wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-outstanding
Floating agent.
Composition includes following component and content when wettable powder is made：Active components A 0.5%~80%, activity into
Divide B 0.5%~60%, dispersant 1%~12%, wetting agent 1%~8%, filler surplus.
Composition includes following component and content when water dispersible granules are made：Active components A 0.5%~80%, activity into
Point B 0.5%~60%, dispersant 1%~12%, wetting agent 1%~8%, disintegrant 1%~10%, binding agent 0~8%,
Filler surplus.
Composition includes following component and content when suspending agent is made：Active components A 0.5%~50%, active component B
0.5%~50%, dispersant 1%~10%, wetting agent 1%~10%, defoamer 0.01%~2%, thickener 0~2%, anti-
Freeze agent 0~8%, deionized water and add to 100%.
Composition includes following component and content when suspension emulsion is made：Active components A 0.5%~50%, active component B
0.5%~50%, emulsifying agent 1%~10%, dispersant 1%~10%, solvent 1%~20%, defoamer 0.01%~2%,
Thickener 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when microemulsion is made：Active components A 0.5%~50%, active component
B0.5%~50%, emulsifying agent 3%~25%, solvent 1%~20%, antifreeze 0~8%, defoamer 0.01%~2%, go
Ionized water adds to 100%.
Composition includes following component and content when aqueous emulsion is made：Active components A 0.5%~50%, active component B
0.5%~50%, solvent 1%~20%, emulsifying agent 1%~12%, antifreeze 0~8%, defoamer 0.01%~2%, thickening
Agent 0~2%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspending agent is made：Active components A 0.5%~50%, activity into
Divide B0.5%~50%, macromolecule cyst material 1%~10%, dispersant 2%~10%, solvent 1%~10%, emulsifying agent
1%~7%, pH adjusting agent 0.01%~5%, defoamer 0.01%~2%, deionized water add to 100%.
Composition includes following component and content when microcapsule suspension-suspendinagent agent is made：Active components A 0.5%~50%, work
It is property composition B0.5%~50%, macromolecule cyst material 1%~12%, dispersant 1%~12%, wetting agent 1%~8%, molten
Agent 1%~15%, emulsifying agent 1%~8%, defoamer 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~
5%th, deionized water adds to 100%.
The wettable powder the key technical indexes of the present invention：
The water dispersible granules the key technical indexes of the present invention：
The suspending agent the key technical indexes of the present invention：
The suspension emulsion the key technical indexes of the present invention：
The microemulsion the key technical indexes of the present invention：
The aqueous emulsion the key technical indexes of the present invention：
The microcapsule suspending agent the key technical indexes of the present invention：
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention：
The advantage of the invention is that：
(1) Spiromesifen is with after tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide compounding, having
There are obvious synergy and lasting effect；(2) to the whitefly in bt cotton on crops, Tetranychus urticae, red spider, leaf roller, beet armyworm,
Prodenia litura, diamondback moth, tea geometrid, corn borer, striped rice borer, armyworm, pine moth, aphid, trialeurodes vaporariorum, small heart-eating peach worm, cotton boll
Worm, cutworm, cabbage caterpillar etc. have greater activity；(3) pesticide usage amount is reduced, residual of the agricultural chemicals on crop is reduced
Amount, alleviates environmental pollution；(4) to person poultry safety, Environmental compatibility is good, and preparation adhesion strength strengthens, resistance of rainwater washing against.
Embodiment
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is weight percentage, but
The invention is not limited in this.
Application Example one
The wettable powder of example 1~16
Spiromesifen, active component B, dispersant, wetting agent, filler are well mixed in mixed cylinder, through air-flow crushing
Machine remixes uniform after crushing, you can wettable powder product of the present invention is made, 1 is specifically shown in Table.
The each component of 1 embodiment of table 1~16 and content
The water dispersible granules of example 17~32
Spiromesifen, active component B, dispersant, wetting agent, disintegrant, filler etc. are needed through air-flow crushing together
The particle diameter wanted, adds other auxiliary agents such as binding agent (can add to be not added with), obtains materials of pelletizing.Item is quantified into feeding fluid bed
In granulating drier after granulation and drying, you can water dispersible granules product of the present invention is made, 2 are specifically shown in Table.
The each component of 2 embodiment of table 17~32 and content
The suspending agent of example 33~48
By dispersant, wetting agent, defoamer, thickener (can add to be not added with), antifreeze (can add to be not added with), by a high speed
Shear-mixed is uniform, adds Spiromesifen, active component B, ball milling 2~3 hours in ball mill make diameter of particle all in 5 μ
Below m, surplus is supplied with deionized water, you can suspending agent product of the present invention is made, 3 are specifically shown in Table.
The each component of 3 embodiment of table 33~48 and content
The suspension emulsion of example 49~58
Dispersant, defoamer, thickener (can add to be not added with), antifreeze (can add to be not added with) are mixed by high speed shear
Uniformly, Spiromesifen is added, ball milling 2~3 hours in ball mill make diameter of particle all below 5 μm, Spiromesifen is made
Suspending agent, then directly emulsifies active component B, emulsifying agent, solvent and various auxiliary agents in suspending agent with high speed agitator, system
Obtain suspension emulsion product of the present invention.Specifically it is shown in Table 4,5.
The component of 4 example of table 49~53 and content
The component of 5 example of table 54~58 and content
Tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide in table 1~5 are exchanged, can be made new
Preparation.
The aqueous emulsion of embodiment 59~61
Spiromesifen, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；By deionized water,
Antifreeze (can add to be not added with), thickener (can add to be not added with), defoamer are mixed, into homogeneous aqueous phase.In high-speed stirred
Under, aqueous phase is added into oil phase, aqueous emulsion product of the present invention is made.Specifically it is shown in Table 6.
The each component of 6 embodiment of table 59~61 and content
The microemulsion of embodiment 62~64
Spiromesifen, active component B are dissolved in the homogenizer equipped with solvent, by emulsifying agent, antifreeze, (can add can not
Plus), defoamer be added in the homogenizer equipped with above-mentioned solution, supplied with deionized water give after surplus strongly mixing and it is even
Change, finally obtain the transparent microemulsion product of the present invention of clear appearance.Specifically it is shown in Table 7.
The each component of 7 embodiment of table 62~64 and content
The microcapsule suspending agent of embodiment 65~67
Spiromesifen, active component B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, in shearing
Under the conditions of, oil phase is added to containing in emulsifying agent, pH adjusting agent, dispersant, the aqueous phase solution of defoamer, mended with deionized water
Sufficient surplus, two kinds of materials react in oil-water interfaces, form high score ascus wall, and well dispersed micro- of the present composition is made
Capsule suspending agent product.Specifically it is shown in Table 8.
The each component of 8 embodiment of table 65~67 and content
The microcapsule suspension-suspendinagent agent of embodiment 68~70
Active component B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase, by oil phase in shearing condition
Under be added to containing in emulsifying agent, the aqueous phase solution of pH adjusting agent, well dispersed microcapsule suspending agent is made.By dispersant, wet
Profit agent, defoamer, thickener (can add to be not added with) are well mixed by high speed shear, add Spiromesifen, the ball in ball mill
Mill 2~3 hours, makes diameter of particle all below 5 μm, and suspending agent is made, suspending agent then is added into micro-capsule suspension
Aqueous phase solution in, deionized water supplies surplus, and the well dispersed microcapsule suspension-suspendinagent agent product of the present composition is made.
Specifically it is shown in Table 9.
The each component of 9 embodiment of table 68~70 and content
The embodiment of the present invention is the method being combined using Toxicity Determination and field test.First pass through indoor virulence survey
Calmly, the co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are compounded by a certain percentage, CTC ＜ 80 are antagonism, 80≤CTC≤120
For summation action, CTC ＞ 120 are synergistic effect, on this basis, then carry out field test.
Test method：The mother liquor of each mixed agent is diluted to five series concentrations respectively during experiment, is respectively placed in beaker
It is standby.Using the first leaching leaf method that is followed by worm, by not in contact with the blade of the same size of any medicament in the decoction configured
Take out, dry naturally after immersion 5s, be put into insect box, then connect for examination larva, raised under the conditions of 25 DEG C, often handle 3
Secondary repetition, it is 50 often to repeat test worm number used, while setting blank control, dead borer population is checked in 72h, the death rate and correction is calculated
The death rate, tries to achieve virulence regression equation and calculates LC50Value.If compareing the death rate is more than 10%, it is considered as invalid experiment.Calculate public
Formula is as follows：
Insect corrected mortality is converted into probit value (y), concentration for the treatment of (μ g/ml) is converted into logarithm value (x), with minimum
Square law draws virulence regression equation, and thus calculates the value of every kind of medicament.Common poison system is calculated according to the abundant equations of Sun Yun
Number CTC.Calculation formula is following, and (using Spiromesifen as standard agent, 100) its toxicity index is：
TI × P of M theoretical toxicity index (TTI)=SpiromesifenSpiromesifen+ effective active composition B TI × PEffective active composition B
In formula：M is the mixture of different ratio
PEffective active composition BFor effective active composition B shared ratios in the composition
PSpiromesifenFor Spiromesifen shared ratio in the composition
B is selected from one of tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide and planted.
Application Example two：
For examination insect：Laphygma exigua Hubner
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：The effective of Spiromesifen and tebufenozide active compound and the two different ratio mixture is determined by pilot study
Lethasl concentration scope.
Toxicity test result
The Spiromesifen of table 10 compounds the toxicity test analysis of results table to Laphygma exigua Hubner with tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Spiromesifen | — | 1.89 | — |
| Tebufenozide | — | 4.69 | — |
| Luo first Man Zhi ︰ tebufenozides | 80:1 | 0.98 | 194.29 |
| Luo first Man Zhi ︰ tebufenozides | 60:1 | 0.97 | 196.77 |
| Luo first Man Zhi ︰ tebufenozides | 40:1 | 0.96 | 199.78 |
| Luo first Man Zhi ︰ tebufenozides | 20:1 | 0.95 | 204.77 |
| Luo first Man Zhi ︰ tebufenozides | 10:1 | 0.90 | 222.05 |
| Luo first Man Zhi ︰ tebufenozides | 5:1 | 0.91 | 230.64 |
| Luo first Man Zhi ︰ tebufenozides | 1:1 | 1.14 | 236.34 |
| Luo first Man Zhi ︰ tebufenozides | 2:5 | 1.35 | 244.09 |
| Luo first Man Zhi ︰ tebufenozides | 1:6 | 1.60 | 241.92 |
| Luo first Man Zhi ︰ tebufenozides | 1:15 | 1.83 | 234.31 |
| Luo first Man Zhi ︰ tebufenozides | 1:25 | 1.99 | 222.97 |
| Luo first Man Zhi ︰ tebufenozides | 1:40 | 2.24 | 202.07 |
| Luo first Man Zhi ︰ tebufenozides | 1:60 | 2.35 | 194.84 |
As shown in Table 10, Spiromesifen compounds the proportioning for preventing and treating Laphygma exigua Hubner in 1 60~80 ︰ 1 of ︰ with tebufenozide,
Co-toxicity coefficient is all higher than 120, illustrate both in the range of the ︰ 1 of 1 ︰ 60~80 mixture show synergistic effect, when Spiromesifen with
The proportioning of tebufenozide is in 1 25~10 ︰ 1 of ︰, and synergistic effect is more prominent, and co-toxicity coefficient is all higher than 220, tests and sends out through applicant
Now Spiromesifen and the optimum ratio of tebufenozide are 10：1、5：1、4：1、3：1、2：1、1：1、1：2、2：5、1：3、1：4、1：5、1：
6、1：7、1：8、1：9、1：10、1：11、1：12、1：13、1：14、1：15、1：20、1：25, wherein when Spiromesifen and tebufenozide
Co-toxicity coefficient is maximum when weight ratio is 2 ︰ 5, and synergistic effect is the most obvious.
Application Example three
For examination insect：Rice-stem borer
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Spiromesifen and methoxyfenozide active compound and the two different ratio mixture are determined by pilot study
Effective lethasl concentration scope.
The Spiromesifen of table 11 compounds the toxicity test analysis of results table to rice-stem borer with methoxyfenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Spiromesifen | — | 1.65 | — |
| Methoxyfenozide | — | 0.83 | — |
| Luo first Man Zhi ︰ methoxyfenozides | 80:1 | 0.84 | 194.06 |
| Luo first Man Zhi ︰ methoxyfenozides | 60:1 | 0.81 | 200.46 |
| Luo first Man Zhi ︰ methoxyfenozides | 40:1 | 0.78 | 206.56 |
| Luo first Man Zhi ︰ methoxyfenozides | 30:1 | 0.73 | 219.05 |
| Luo first Man Zhi ︰ methoxyfenozides | 19:1 | 0.71 | 221.46 |
| Luo first Man Zhi ︰ methoxyfenozides | 14:1 | 0.69 | 224.35 |
| Luo first Man Zhi ︰ methoxyfenozides | 10:1 | 0.65 | 232.93 |
| Luo first Man Zhi ︰ methoxyfenozides | 6:1 | 0.60 | 240.99 |
| Luo first Man Zhi ︰ methoxyfenozides | 2:1 | 0.50 | 248.25 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:1 | 0.45 | 245.43 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:5 | 0.38 | 238.15 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:9 | 0.39 | 223.95 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:15 | 0.40 | 214.15 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:25 | 0.42 | 201.47 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:40 | 0.43 | 195.39 |
| Luo first Man Zhi ︰ methoxyfenozides | 1:60 | 0.44 | 190.19 |
As shown in Table 11, Spiromesifen compounds the proportioning of preventing and treating rice-stem borer in the ︰ 1 of 1 ︰ 60~80 with methoxyfenozide
When, co-toxicity coefficient is all higher than 120, illustrates that both show synergistic effect at the mixture in the range of the ︰ 1 of 1 ︰ 60~80, when spiral shell first mite
The proportioning of ester and methoxyfenozide is in 1 15~30 ︰ 1 of ︰, and synergistic effect is more prominent, and co-toxicity coefficient is all higher than 210, through application
People's experiment finds that the optimum ratio of Spiromesifen and methoxyfenozide is 30：1、25：1、20：1、15：1、10：1、9：1、8：1、7：
1、6：1、5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：15, wherein working as spiral shell
Co-toxicity coefficient is maximum when first mite ester is 2 ︰ 1 with methoxyfenozide weight ratio, and synergistic effect is the most obvious.
Application Example four
For examination insect：Brassicaceous vegetable diamondback moth
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Spiromesifen and furan tebufenozide active compound and the two different ratio mixture are determined by pilot study
Effective lethasl concentration scope
The Spiromesifen of table 12 compounds the toxicity test analysis of results table to brassicaceous vegetable diamondback moth with furan tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Spiromesifen | — | 1.78 | — |
| Furan tebufenozide | — | 1.69 | — |
| Luo first Man Zhi ︰ furan tebufenozides | 80:1 | 0.96 | 185.29 |
| Luo first Man Zhi ︰ furan tebufenozides | 60:1 | 0.94 | 189.00 |
| Luo first Man Zhi ︰ furan tebufenozides | 40:1 | 0.92 | 193.23 |
| Luo first Man Zhi ︰ furan tebufenozides | 20:1 | 0.83 | 213.92 |
| Luo first Man Zhi ︰ furan tebufenozides | 10:1 | 0.81 | 218.69 |
| Luo first Man Zhi ︰ furan tebufenozides | 4:1 | 0.79 | 222.94 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:1 | 0.75 | 231.18 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:4 | 0.76 | 224.64 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:10 | 0.77 | 220.49 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:20 | 0.79 | 214.44 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:40 | 0.88 | 192.28 |
| Luo first Man Zhi ︰ furan tebufenozides | 1:60 | 0.90 | 187.93 |
As shown in Table 12, Spiromesifen compounds the proportioning of preventing and treating brassicaceous vegetable diamondback moth in 1 ︰ 60 with furan tebufenozide
During~80 ︰ 1, co-toxicity coefficient is all higher than 120, illustrates that both show synergistic effect at the mixture in the range of the ︰ 1 of 1 ︰ 60~80, when
The proportioning of Spiromesifen and furan tebufenozide is in 1 20~20 ︰ 1 of ︰, and synergistic effect is more prominent, and co-toxicity coefficient is all higher than 210,
Tested through applicant and find that the optimum ratio of Spiromesifen and furan tebufenozide is 20：1、15：1、10：1、9：1、8：1、7：1、6：
1、5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：15、1：20, wherein working as spiral shell
Co-toxicity coefficient is maximum when first mite ester is 1 ︰ 1 with furan tebufenozide weight ratio, and synergistic effect is the most obvious.
Application Example five
For examination insect：Apple small heart-eating peach worm
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Having for Spiromesifen and ring tebufenozide active compound and the two different ratio mixture is determined by pilot study
Imitate lethasl concentration scope.
The Spiromesifen of table 13 compounds the toxicity test analysis of results table to apple small heart-eating peach worm with ring tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Spiromesifen | — | 1.91 | — |
| Ring tebufenozide | — | 1.01 | — |
| Luo first Man Zhi ︰ ring tebufenozides | 80:1 | 0.96 | 196.79 |
| Luo first Man Zhi ︰ ring tebufenozides | 60:1 | 0.94 | 200.05 |
| Luo first Man Zhi ︰ ring tebufenozides | 40:1 | 0.92 | 203.19 |
| Luo first Man Zhi ︰ ring tebufenozides | 30:1 | 0.83 | 223.69 |
| Luo first Man Zhi ︰ ring tebufenozides | 19:1 | 0.81 | 225.74 |
| Luo first Man Zhi ︰ ring tebufenozides | 14:1 | 0.79 | 228.21 |
| Luo first Man Zhi ︰ ring tebufenozides | 10:1 | 0.75 | 235.58 |
| Luo first Man Zhi ︰ ring tebufenozides | 6:1 | 0.70 | 242.05 |
| Luo first Man Zhi ︰ ring tebufenozides | 2:1 | 0.60 | 245.43 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:1 | 0.55 | 240.24 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:5 | 0.46 | 238.28 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:9 | 0.46 | 230.42 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:15 | 0.47 | 221.41 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:25 | 0.50 | 205.73 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:40 | 0.51 | 200.34 |
| Luo first Man Zhi ︰ ring tebufenozides | 1:60 | 0.52 | 195.74 |
As shown in Table 13, Spiromesifen compounds the proportioning of preventing and treating apple small heart-eating peach worm in the ︰ 1 of 1 ︰ 60~80 with ring tebufenozide
When, co-toxicity coefficient is all higher than 120, illustrates that both show synergistic effect at the mixture in the range of the ︰ 1 of 1 ︰ 60~80, when spiral shell first mite
The proportioning of ester and ring tebufenozide is in 1 15~30 ︰ 1 of ︰, and synergistic effect is more prominent, and co-toxicity coefficient is all higher than 220, through applicant
Experiment finds that the optimum ratio of Spiromesifen and ring tebufenozide is 30：1、25：1、20：1、15：1、10：1、9：1、8：1、7：1、6：
1、5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：15, wherein when spiral shell first mite
Co-toxicity coefficient is maximum when ester is 2 ︰ 1 with ring tebufenozide weight ratio, and synergistic effect is the most obvious.
Application Example six
For examination insect：Cotton boll worm
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
Experimental design：Having for Spiromesifen and chlorine tebufenozide active compound and the two different ratio mixture is determined by pilot study
Imitate lethasl concentration scope
The Spiromesifen of table 14 compounds the toxicity test analysis of results table to cotton boll worm with chlorine tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Spiromesifen | — | 1.79 | — |
| Chlorine tebufenozide | — | 0.52 | — |
| Luo first Man Zhi ︰ chlorine tebufenozides | 80:1 | 0.91 | 190.95 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 60:1 | 0.88 | 195.58 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 40:1 | 0.85 | 198.75 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 30:1 | 0.75 | 221.24 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 21:1 | 0.72 | 223.77 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 15:1 | 0.67 | 231.78 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 9:1 | 0.61 | 235.84 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 4:1 | 0.50 | 240.52 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:1 | 0.34 | 237.03 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:5 | 0.25 | 235.89 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:10 | 0.25 | 222.34 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:20 | 0.26 | 206.99 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:40 | 0.27 | 195.98 |
| Luo first Man Zhi ︰ chlorine tebufenozides | 1:60 | 0.28 | 187.90 |
As shown in Table 14, Spiromesifen compounds the proportioning for preventing and treating cotton boll worm in 1 60~80 ︰ 1 of ︰ with chlorine tebufenozide,
Co-toxicity coefficient is all higher than 120, illustrate both in the range of the ︰ 1 of 1 ︰ 60~80 mixture show synergistic effect, when Spiromesifen with
The proportioning of chlorine tebufenozide is in 1 10~30 ︰ 1 of ︰, and synergistic effect is more prominent, and co-toxicity coefficient is all higher than 220, is tested through applicant
It was found that Spiromesifen and the optimum ratio of chlorine tebufenozide are 30：1、25：1、20：1、15：1、14：1、13：1、12：1、11：1、10：
1、9：1、8：1、7：1、6：1、5：1、4：1、3：1、2：1、1：1、1：2、1：3、1：4、1：5、1：10, wherein when Spiromesifen and chlorine
Co-toxicity coefficient is maximum when tebufenozide weight ratio is 4 ︰ 1, and synergistic effect is the most obvious.
Found through experiment：Spiromesifen and active component B compound after to the whitefly in bt cotton in various crop, Tetranychus urticae, red
It is spider, leaf roller, beet armyworm, prodenia litura, diamondback moth, tea geometrid, corn borer, striped rice borer, armyworm, pine moth, aphid, white
Aleyrodid, small heart-eating peach worm, bollworm, cutworm, the preventing and treating of cabbage caterpillar have obvious synergistic effect, and co-toxicity coefficient is 120
More than.
Test of pesticide effectiveness part test medicament is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, the spiral shell of comparison medicament 24%
First mite ester suspending agent (autogamy), 20% Tebufenozide suspending agent (purchased in market), 240g/L methoxyfenozides suspending agent (purchased in market), 10% furan
Mutter Tebufenozide suspending agent (autogamy), 5% chromafenozide suspending agent (autogamy), 15% chlorine tebufenozide granule (autogamy).
The Spiromesifen of Application Example seven and active component B and its compounding preventing and treating Laphygma exigua Hubner test of pesticide effectiveness
This test arrangement investigates Laphygma exigua Hubner insect pest index before Xian District, Shanxi Province suburban area, medicine, occurs in insect pest
Dispenser at initial stage, 3 days after dispenser, investigates insect pest indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
The Spiromesifen of table 15 and active component B and its compounding preventing and treating Laphygma exigua Hubner test of pesticide effectiveness
As can be seen from Table 15, Spiromesifen is with can effectively prevent and treat Laphygma exigua Hubner, preventing and treating effect after active component B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long, and can prevent and treat wild cabbage diamondback moth, cabbage caterpillar, prodenia litura, and preventive effect is equal
More than 96%.Target crop is had no adverse effects in experiment scope of medication.
The Spiromesifen of Application Example eight and active component B and its compounding preventing and treating rice-stem borer test of pesticide effectiveness
This test arrangement investigates rice-stem borer insect pest index before Shaanxi Province's Hanzhong City, medicine, is applied in insect pest early period of origination
Medicine, 10 days after dispenser, investigates insect pest indexes and calculates preventive effect for 20 days, 30 days.Result of the test is as follows：
The Spiromesifen of table 16 and active component B and its compounding preventing and treating rice-stem borer test of pesticide effectiveness
As can be seen from Table 16, Spiromesifen after active component B compoundings with can effectively prevent and treat rice-stem borer, prevention effect
The preventive effect of single dose is superior to, and preventive effect phase is long.Target crop is had no adverse effects in experiment scope of medication.
The Spiromesifen of Application Example nine and active component B and its compounding preventing and treating apple Tetranychus urticae test of pesticide effectiveness
This test arrangement investigates apple Tetranychus urticae insect pest index before Xianyang, Shanxi province city, medicine, in insect pest early period of origination
Dispenser, 7 days after dispenser, investigates insect pest indexes and calculates preventive effect for 14 days, 20 days.Result of the test is as follows：
The Spiromesifen of table 17 and active component B and its compounding preventing and treating apple Tetranychus urticae test of pesticide effectiveness
As can be seen from Table 17, Spiromesifen is with can effectively prevent and treat apple Tetranychus urticae, preventing and treating effect after active component B compoundings
Fruit is superior to the preventive effect of single dose, and preventive effect phase is long, and can prevent and treat European red mite, and preventive effect is all higher than 96%.In experiment
Target crop is had no adverse effects in scope of medication.
The Spiromesifen of Application Example ten and active component B and its compounding preventing and treating cotton boll worm test of pesticide effectiveness
This test arrangement investigates cotton boll pests index before Shaanxi Province Dali County, medicine, is applied in insect pest early period of origination
Medicine, 3 days after dispenser, investigates insect pest indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
The Spiromesifen of table 18 and active component B and its compounding preventing and treating cotton boll worm test of pesticide effectiveness
As can be seen from Table 18, Spiromesifen after active component B compoundings with can effectively prevent and treat cotton boll worm, prevention effect
The preventive effect of single dose is superior to, and preventive effect phase is long, and cotton whitefly in bt cotton, red spider can be prevented and treated, and preventive effect is all higher than 96%.
Target crop is had no adverse effects in experiment scope of medication.
The Spiromesifen of Application Example 11 is tried with active component B and its compounding preventing and treating brassicaceous vegetable cabbage caterpillar drug effect
Test
This test arrangement investigates brassicaceous vegetable dark greyish green pests index before Xian District, Shanxi Province suburban area, medicine, in worm
Evil early period of origination dispenser, 3 days after dispenser, investigates insect pest indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
The Spiromesifen of table 19 and active component B and its compounding preventing and treating brassicaceous vegetable cabbage caterpillar test of pesticide effectiveness
As can be seen from Table 19, Spiromesifen can effectively prevent and treat brassicaceous vegetable cabbage caterpillar after being compounded with active component B,
Prevention effect is superior to the preventive effect of single dose, and preventive effect phase is long, and can prevent and treat apple brassicaceous vegetable beet armyworm, pickles
Moth, prodenia litura, and preventive effect is all higher than 96%.Target crop is had no adverse effects in experiment scope of medication.
The Spiromesifen of Application Example 12 and active component B and its compounding preventing and treating apple small heart-eating peach worm test of pesticide effectiveness
This test arrangement investigates apple small heart-eating peach worm insect pest index before Shaanxi Province's Weinan City, medicine, occurs just in insect pest
Phase dispenser, 10 days after dispenser, investigates insect pest indexes and calculates preventive effect for 20 days, 30 days.Result of the test is as follows：
The Spiromesifen of table 20 and active component B and its compounding preventing and treating apple small heart-eating peach worm test of pesticide effectiveness
As can be seen from Table 20, Spiromesifen is prevented and treated with can effectively prevent and treat apple small heart-eating peach worm after active component B compoundings
Effect is superior to the preventive effect of single dose, and preventive effect phase is long, and can prevent and treat apple skin worm, and preventive effect is all higher than 96%.In examination
Test and target crop is had no adverse effects in scope of medication.
The Spiromesifen of Application Example 13 and active component B and its compounding preventing and treating tomato trialeurodes vaporariorum test of pesticide effectiveness
This test arrangement investigates tomato trialeurodes vaporariorum insect pest index before Xian District, Shanxi Province suburban area, medicine, occurs just in insect pest
Phase dispenser, 3 days after dispenser, investigates insect pest indexes and calculates preventive effect for 7 days, 15 days.Result of the test is as follows：
The Spiromesifen of table 21 and active component B and its compounding preventing and treating tomato trialeurodes vaporariorum test of pesticide effectiveness
As can be seen from Table 21, Spiromesifen after active component B compoundings with can effectively prevent and treat tomato trialeurodes vaporariorum, prevention effect
The preventive effect of single dose is superior to, and preventive effect phase is long, and tomato aphid can be prevented and treated, and preventive effect is all higher than 96%.In experiment medication
In the range of target crop is had no adverse effects.
The experiment by different places throughout the country is drawn afterwards, Spiromesifen and tebufenozide, methoxyfenozide, furans worm
To the whitefly in bt cotton in various crop, Tetranychus urticae, red spider, leaf roller, beet after hydrazides, ring tebufenozide, chlorine tebufenozide compounding
Noctuid, prodenia litura, diamondback moth, tea geometrid, corn borer, striped rice borer, armyworm, pine moth, aphid, trialeurodes vaporariorum, small heart-eating peach worm,
The preventive effect of the common insect pests such as bollworm, cutworm, cabbage caterpillar is more than 95%, and better than single dose preventive effect, synergistic effect is obvious.
Claims (6)
1. a kind of composition pesticide containing Spiromesifen and bishydrazide, containing active components A and active component B, its feature exists
In：Active components A and active component B weight ratio are the ︰ 1 of 1 ︰ 60 ~ 80, and described active components A is selected from Spiromesifen, activity into
Divide B to be selected from one of furan tebufenozide, ring tebufenozide, chlorine tebufenozide to plant.
2. the composition pesticide according to claim 1 containing Spiromesifen and bishydrazide, it is characterised in that：Active component
A and active component B weight ratio is the ︰ 1 of 1 ︰ 40 ~ 60.
3. the composition pesticide according to claim 2 containing Spiromesifen and bishydrazide, it is characterised in that：
The weight ratio of Spiromesifen and furan tebufenozide is the ︰ 1 of 1 ︰ 20 ~ 20；
The weight ratio of Spiromesifen and ring tebufenozide is the ︰ 1 of 1 ︰ 15 ~ 30；
The weight ratio of Spiromesifen and chlorine tebufenozide is the ︰ 1 of 1 ︰ 10 ~ 30.
4. the composition pesticide according to any one of claim 1 to 3 containing Spiromesifen and bishydrazide, its feature exists
In：Wettable powder is made in composition, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, micro-
Capsule suspension-suspending agent.
5. the composition pesticide according to claim 4 containing Spiromesifen and bishydrazide is used to prevent and treat insect on crops
Purposes.
6. purposes according to claim 5, it is characterised in that：Described insect include whitefly in bt cotton, red spider, leaf roller,
The small food of beet armyworm, prodenia litura, diamondback moth, tea geometrid, corn borer, striped rice borer, armyworm, pine moth, aphid, trialeurodes vaporariorum, peach
Heart worm, bollworm, cutworm, cabbage caterpillar.
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| CN201210310713.9A CN103621503B (en) | 2012-08-29 | 2012-08-29 | A kind of composition pesticide containing Spiromesifen and bishydrazide |
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|---|---|---|---|
| CN201210310713.9A Expired - Fee Related CN103621503B (en) | 2012-08-29 | 2012-08-29 | A kind of composition pesticide containing Spiromesifen and bishydrazide |
| CN201510681196.XA Expired - Fee Related CN105248421B (en) | 2012-08-29 | 2012-08-29 | A kind of composition pesticide containing Spiromesifen and bishydrazide |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210310713.9A Expired - Fee Related CN103621503B (en) | 2012-08-29 | 2012-08-29 | A kind of composition pesticide containing Spiromesifen and bishydrazide |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN103621503B (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10007411A1 (en) * | 2000-02-18 | 2001-08-23 | Bayer Ag | Active ingredient combinations with insecticidal and acaricidal properties |
| JP2006213664A (en) * | 2005-02-04 | 2006-08-17 | Mitsui Chemicals Inc | Plant disease control composition and its control method |
| EP2039248A1 (en) * | 2007-09-21 | 2009-03-25 | Bayer CropScience AG | Active agent combinations with insecticide and acaricide properties |
| RS55986B1 (en) * | 2010-01-22 | 2017-09-29 | Bayer Ip Gmbh | Acaricides and/or insecticidal agent combinations |
-
2012
- 2012-08-29 CN CN201210310713.9A patent/CN103621503B/en not_active Expired - Fee Related
- 2012-08-29 CN CN201510681196.XA patent/CN105248421B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN103621503A (en) | 2014-03-12 |
| CN103621503B (en) | 2016-01-13 |
| CN105248421A (en) | 2016-01-20 |
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Address after: 715500 Pucheng high tech Industrial Development Zone, Weinan, Shaanxi Patentee after: SHAANXI MEIBANG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 715500 Industrial Park of Agrochemical Base, Pucheng County, Weinan City, Shaanxi Province Patentee before: Shaanxi Meibang pesticide Co.,Ltd. |
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Granted publication date: 20170825 |