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CN104225100A - Drug for treating knee osteoarthritis - Google Patents

Drug for treating knee osteoarthritis Download PDF

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Publication number
CN104225100A
CN104225100A CN201310249550.2A CN201310249550A CN104225100A CN 104225100 A CN104225100 A CN 104225100A CN 201310249550 A CN201310249550 A CN 201310249550A CN 104225100 A CN104225100 A CN 104225100A
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CN
China
Prior art keywords
parts
radix
drug
knee osteoarthritis
wind
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Pending
Application number
CN201310249550.2A
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Chinese (zh)
Inventor
陈冠卿
陈洪涛
陈洪波
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Individual
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Individual
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Priority to CN201310249550.2A priority Critical patent/CN104225100A/en
Publication of CN104225100A publication Critical patent/CN104225100A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a drug for treating knee osteoarthritis and belongs to the technical field of traditional Chinese medicine preparations. The drug mainly consists of 12 raw material medicines such as rhizoma curculiginis, prepared rehmannia root, honeysuckle stem, spina gleditsiae, radix clematidis, herba epimedii, cynanchum paniculatum and mulberry twig which are processed to reach the requirement by virtue of a drug preparation apparatus and then made into different dosage forms such as capsules and tablets for later use. The drug has the effects of strengthening yang-qi, tonifying kidneys, dispelling the wind, activating blood, dredging collaterals and relieving pains, has good curative effect on knee osteoarthritis, and is free of toxic and side effect.

Description

The medicine for the treatment of knee osteoarthritis
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation.
Background technology
Knee osteoarthritis is a kind of commonly encountered diseases, frequently-occurring disease, how to occur in middle-aged and elderly people.Main manifestations is arthralgia and tenderness, can have swelling, stiff, moving obstacle, leg muscle atrophy time serious, and turning up or Varus deformity can appear in joint.Modern medicine does not also have highly effective Therapeutic Method to knee osteoarthritis.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of medicine for the treatment of knee osteoarthritis is newly provided.It has invigorating YANG the kidney invigorating, expelling wind and activating blood circulation, effect of removing obstruction in the collateral to relieve pain, effective to treatment knee osteoarthritis.Determined curative effect can be reached, the object had no side effect.
The technical solution adopted for the present invention to solve the technical problems is: be made up of Rhizoma Curculiginis, Radix Rehmanniae Preparata, Caulis Lonicerae, Spina Gleditsiae, Radix Clematidis, Herba Epimedii, Radix Morindae Officinalis, Radix Gentianae Macrophyllae, Radix Cynanchi Paniculati, Ramulus Mori, Radix Angelicae Sinensis, the Radix Paeoniae Alba 12 kinds of crude drug.
About ingredient major function and preparation in invention formulation.
Rhizoma Curculiginis in the present invention, nature and flavor are pungent, bitter, sweet, temperature.Containing tannin, fatty oil, resin, starch, alkaloid etc.The warm essence of tonifying YANG, cold expelling eliminating impediment.Cure mainly decline of the fire from the gate of life, impotence and seminal emission, muscles and bones flaccidity is soft, cold arthralgia of loins and legs.
Radix Rehmanniae Preparata in the present invention, nature and flavor are sweet, tepor.Containing mannitol, glucose, alkaloid, fatty acid, rehmanin etc.Enriching yin and nourishing kidney, tonifying blood and regulating menstruation.Cure mainly deficiency of YIN insufficiency of blood, damage of essence strains, and the soreness of waist is dizzy, deaf, menoxenia, metrorrhagia, early whitening of beard and hair.
Caulis Lonicerae in the present invention, nature and flavor are sweet, cold.Containing lonicerin, tannin, alkaloid etc.Heat-clearing and toxic substances removing.Cure mainly epidemic febrile disease heating, carbuncle, scabies, malignant boil, toxic swelling, pyretic toxicity, dysentery.
Spina Gleditsiae in the present invention, nature and flavor are pungent, temperature.Containing flavonoid glycoside, phenols, aminoacid.Dissatisfied wind, parasite killing, poison holding, carbuncle of bursting.Cure mainly carbuncle, sore, malignant boil swells and ache non-Collapse, tinea skin ulcer, placenta retention.
Radix Clematidis in the present invention, nature and flavor are pungent, salty, temperature.Containing anemonin, Radix Pulsatillae alcohol, sterol, saccharide, Saponin etc.Wind-damp dispelling, pain relieving, changes fishbone.Cure mainly rheumatic arthralgia, waist and limbs pain, lump in the abdomen.
Herba Epimedii in the present invention, nature and flavor are pungent, temperature.Containing icariine, desmethylicariin, alkaloid etc.Invigorating the liver and kidney, bone and muscle strengthening, supporing yang benefit essence, expelling wind and removing dampness.Cure mainly sexual impotence, soreness of the waist and knees, anemofrigid-damp arthralgia, hemiplegia, dribbling urination, muscles and bones contraction is anxious.
Radix Morindae Officinalis in the present invention, nature and flavor are sweet, pungent, tepor.Containing plant sterol, Anthraquinones, saccharide, resin, the vitamin third gradegrade C.Warming the kidney to invigorate YANG, bone and muscle strengthening.Cure mainly impotence and premature ejaculation, soreness of the waist and knees, few abdomen cold type of pain, anemofrigid-damp arthralgia.
Radix Gentianae Macrophyllae in the present invention, nature and flavor are bitter, pungent, flat.Containing Radix Gentianae Macrophyllae alkaloid first, second, the third, volatile oil, saccharide etc.Loose wind damp eliminating, relaxing muscles and tendons to promote blood circulation.Cure mainly wind and cold arthralgia pain, muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever.
Radix Cynanchi Paniculati in the present invention, nature and flavor are pungent, temperature.Containing paeonol etc.Removing toxic substances and promoting subsidence of swelling, dispelling wind and removing obstruction in the collateral, calm diuresis, dysentery relieving, promoting flow of QI and blood, pain relieving.Cure mainly rheumatalgia, traumatic injury, dysentery, stomachache distension, toothache, liver cirrhosis, ascites etc.
Ramulus Mori in the present invention, nature and flavor are bitter, flat.Containing polysaccharide sample material, organic acid, silicon dioxide, flavonoid etc.Wind-damp dispelling, sharp joint, row water.Cure mainly anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema.
Radix Angelicae Sinensis in the present invention, nature and flavor sweet, acrid, warm.Containing volatile oil, Palmic acid, sucrose, nicotinic acid etc.Enrich blood and invigorate blood circulation, blood stasis dispersing and fresh blood promoting, regulating menstruation is moisturized.Cure mainly headache due to deficiency of blood, pain in the lumbar region, all pains of trusted subordinate, constipation, flaccidity syndrome and arthralgia syndrome, lump in the abdomen, ulcer sores, amenorrhea, menalgia, metrorrhagia.
The Radix Paeoniae Alba in the present invention, nature and flavor are bitter, sour, are slightly cold.Containing volatile oil, benzoic acid, Palmic acid, tannin, sucrose, phlegmatic temperament, paeoniflorin etc.Easing the affected liver to relieve pain, nourish blood yin fluid astringing.Cure mainly stomachache dysentery, waist flank pain, extremity contraction is anxious, menoxenia, bleeding not during menses.
Knee osteoarthritis is many to be occurred at middle-aged and elderly people, is a kind of Hypertrophic or degenerative osteoarthritis.From traditional Chinese medical science angle, the generation of primary disease and patient's deficiency of kidney-essence, be affected by the cold damp, and coagulation of QI-blood is relevant.The present invention has invigorating YANG the kidney invigorating, expelling wind and activating blood circulation, effect of removing obstruction in the collateral to relieve pain, therefore has good therapeutic effect to knee osteoarthritis.The invention has the beneficial effects as follows: prove, to treatment knee osteoarthritis good effect, to have no side effect through clinical practice.
Detailed description of the invention
1. formula and part by weight: Rhizoma Curculiginis 12 parts, Radix Rehmanniae Preparata 18 parts, Caulis Lonicerae 25 parts, Spina Gleditsiae 12 parts, Radix Clematidis 20 parts, Herba Epimedii 15 parts, Radix Morindae Officinalis 12 parts, Radix Gentianae Macrophyllae 15 parts, Radix Cynanchi Paniculati 15 parts, Ramulus Mori 20 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 15 parts.
2. manufacture method: weighed in proportion by above-mentioned raw materials medicine and assort, it is qualified to concoct with pharmaceutical equipment apparatus, purifies, concentrated, makes capsule, tablet, pill, granule, oral liquid different dosage form are for subsequent use after mix homogeneously.

Claims (1)

1. treat a medicine for knee osteoarthritis, it is characterized in that formula and part by weight are Rhizoma Curculiginis 12 parts, Radix Rehmanniae Preparata 18 parts, Caulis Lonicerae 25 parts, Spina Gleditsiae 12 parts, Radix Clematidis 20 parts, Herba Epimedii 15 parts, Radix Morindae Officinalis 12 parts, Radix Gentianae Macrophyllae 15 parts, Radix Cynanchi Paniculati 15 parts, Ramulus Mori 20 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 15 parts; Above-mentioned raw materials medicine is weighed in proportion and assorts, with pharmaceutical equipment apparatus concoct qualified, purify, make capsule, tablet, pill, granule, oral liquid different dosage form after concentrated, mix homogeneously.
CN201310249550.2A 2013-06-23 2013-06-23 Drug for treating knee osteoarthritis Pending CN104225100A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310249550.2A CN104225100A (en) 2013-06-23 2013-06-23 Drug for treating knee osteoarthritis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310249550.2A CN104225100A (en) 2013-06-23 2013-06-23 Drug for treating knee osteoarthritis

Publications (1)

Publication Number Publication Date
CN104225100A true CN104225100A (en) 2014-12-24

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Family Applications (1)

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CN201310249550.2A Pending CN104225100A (en) 2013-06-23 2013-06-23 Drug for treating knee osteoarthritis

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104547091A (en) * 2014-12-31 2015-04-29 贵州泰尔医药研究所 Medicine for treating osteoarthritis and preparation method thereof
CN110755496A (en) * 2019-12-20 2020-02-07 叶臻 Traditional Chinese medicine composition for treating knee osteoarthritis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104547091A (en) * 2014-12-31 2015-04-29 贵州泰尔医药研究所 Medicine for treating osteoarthritis and preparation method thereof
CN104547091B (en) * 2014-12-31 2017-08-25 贵州泰尔医药研究所 It is a kind of to treat medicine of Osteoarthritis and preparation method thereof
CN110755496A (en) * 2019-12-20 2020-02-07 叶臻 Traditional Chinese medicine composition for treating knee osteoarthritis

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PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20141224