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BR9609989A - Compostos de benzilaminopiperidina substituídos - Google Patents

Compostos de benzilaminopiperidina substituídos

Info

Publication number
BR9609989A
BR9609989A BR9609989A BR9609989A BR9609989A BR 9609989 A BR9609989 A BR 9609989A BR 9609989 A BR9609989 A BR 9609989A BR 9609989 A BR9609989 A BR 9609989A BR 9609989 A BR9609989 A BR 9609989A
Authority
BR
Brazil
Prior art keywords
compounds
substituted
substituted benzylaminopiperidine
benzylaminopiperidine compounds
benzylaminopiperidine
Prior art date
Application number
BR9609989A
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9609989A publication Critical patent/BR9609989A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9609989A 1995-08-24 1996-06-10 Compostos de benzilaminopiperidina substituídos BR9609989A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24
PCT/IB1996/000572 WO1997008144A1 (en) 1995-08-24 1996-06-10 Substituted benzylaminopiperidine compounds

Publications (1)

Publication Number Publication Date
BR9609989A true BR9609989A (pt) 1999-07-06

Family

ID=11004362

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9609989A BR9609989A (pt) 1995-08-24 1996-06-10 Compostos de benzilaminopiperidina substituídos

Country Status (41)

Country Link
US (1) US6506775B1 (pt)
EP (2) EP1114817B1 (pt)
JP (1) JP3084069B2 (pt)
KR (1) KR100288673B1 (pt)
CN (1) CN1153764C (pt)
AP (1) AP643A (pt)
AR (1) AR006305A1 (pt)
AT (2) ATE258166T1 (pt)
AU (1) AU702698B2 (pt)
BG (1) BG64126B1 (pt)
BR (1) BR9609989A (pt)
CA (1) CA2227814C (pt)
CO (1) CO4480738A1 (pt)
CZ (1) CZ297543B6 (pt)
DE (2) DE69631390T2 (pt)
DK (2) DK0861235T3 (pt)
DZ (1) DZ2086A1 (pt)
ES (2) ES2163017T3 (pt)
HR (1) HRP960386B1 (pt)
HU (1) HU225480B1 (pt)
IL (1) IL119078A (pt)
IS (1) IS1947B (pt)
MA (1) MA23961A1 (pt)
MX (1) MX9801467A (pt)
MY (1) MY114800A (pt)
NO (1) NO310720B1 (pt)
NZ (1) NZ308207A (pt)
OA (1) OA10666A (pt)
PE (2) PE20010700A1 (pt)
PL (1) PL186773B1 (pt)
PT (2) PT861235E (pt)
RO (1) RO119299B1 (pt)
RU (1) RU2152930C2 (pt)
SI (2) SI1114817T1 (pt)
SK (1) SK282925B6 (pt)
TN (1) TNSN96107A1 (pt)
TR (1) TR199800300T1 (pt)
TW (1) TW340842B (pt)
UA (1) UA48981C2 (pt)
WO (1) WO1997008144A1 (pt)
YU (1) YU49122B (pt)

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MX9706196A (es) * 1996-08-14 1998-02-28 Pfizer Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
DE60007625T2 (de) * 1999-05-06 2004-11-18 Pfizer Products Inc., Groton Substituierte benzolactamverbindungen
RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
HRP20010861A2 (en) 1999-05-21 2003-04-30 Pfizer Prod Inc 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives
EP1095939B1 (en) * 1999-10-18 2004-01-07 Pfizer Products Inc. Process for the preparation of piperidinylaminomethyl trifluoromethyl cyclic ether compounds
CA2324116A1 (en) * 1999-10-25 2001-04-25 Susan Beth Sobolov-Jaynes Nk-1 receptor antagonists and eletriptan for the treatment of migraine
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
JP4907818B2 (ja) 1999-11-03 2012-04-04 エーエムアール テクノロジー インコーポレイテッド アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用
NZ523456A (en) 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
US6407235B1 (en) * 2000-08-21 2002-06-18 Hoffmann-La Roche Inc. Prodrug acid esters of [2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethansulfonyl]phenol
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
AU2004232799A1 (en) 2003-04-18 2004-11-04 Eli Lilly And Company (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists
BRPI0511183A (pt) * 2004-05-21 2007-12-04 Pfizer Prod Inc metabólitos de (+)-(2s, 3s)-3-(2-metóxi-5-trifluorometoxibenzilamino)-2-fenil- piperidina
MX2007000428A (es) 2004-07-15 2008-03-05 Amr Technology Inc Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina.
ES2382814T3 (es) 2005-05-17 2012-06-13 Merck Sharp & Dohme Ltd. Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
NZ565111A (en) 2005-07-15 2011-10-28 Amr Technology Inc Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
JP4879988B2 (ja) 2005-09-29 2012-02-22 メルク・シャープ・エンド・ドーム・コーポレイション メラノコルチン−４受容体モジュレーターとしてのアシル化スピロピペリジン誘導体
SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
CA2770486C (en) 2006-09-22 2014-07-15 Merck Sharp & Dohme Corp. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
BRPI0806245B1 (pt) 2007-01-10 2022-01-25 Msd Italia S.R.L. Compostos de fórmula i e seus usos
AU2008233662B2 (en) 2007-04-02 2012-08-23 Msd K.K. Indoledione derivative
CA2690191C (en) 2007-06-27 2015-07-28 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
EP2247185B1 (en) 2008-03-03 2014-04-16 Tiger Pharmatech Tyrosine kinase inhibitors
WO2009122707A1 (ja) 2008-03-31 2009-10-08 興和株式会社 １，３－ジヒドロイソベンゾフラン誘導体
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
EP2413932A4 (en) 2009-04-01 2012-09-19 Merck Sharp & Dohme INHIBITORS OF AKT ACTIVITY
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
EP2488028B1 (en) 2009-10-14 2020-08-19 Merck Sharp & Dohme Corp. Substituted piperidines that increase p53 activity and the uses thereof
WO2011163330A1 (en) 2010-06-24 2011-12-29 Merck Sharp & Dohme Corp. Novel heterocyclic compounds as erk inhibitors
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HRP20191232T1 (hr) 2010-08-17 2019-11-01 Sirna Therapeutics Inc Inhibicija, posredovana rna interferencijom, ekspresije gena virusa hepatitisa b (hbv) korištenjem kratkih interferirajućih nukleinskih kiselina (sina)
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US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
CZ289960B6 (cs) * 1991-03-26 2002-05-15 Pfizer Inc. Způsob přípravy substituovaných piperidinů
HU224443B1 (hu) * 1991-06-20 2005-09-28 Pfizer Inc. Fluor-alkoxi-benzaldehid-származékok
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
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PT780375E (pt) * 1995-12-21 2002-12-31 Pfizer 3-¬(benzilo substituido em 5)amino|-2-phenilpiperidinas como antagonistas da substancia p
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Also Published As

Publication number Publication date
SK20798A3 (en) 1999-03-12
DZ2086A1 (fr) 2002-07-22
RO119299B1 (ro) 2004-07-30
TR199800300T1 (xx) 1998-06-22
SI0861235T1 (en) 2002-04-30
PL325332A1 (en) 1998-07-20
CO4480738A1 (es) 1997-07-09
AU702698B2 (en) 1999-03-04
CA2227814A1 (en) 1997-03-06
DE69631390D1 (de) 2004-02-26
PL186773B1 (pl) 2004-02-27
CA2227814C (en) 2002-12-31
CN1193961A (zh) 1998-09-23
US6506775B1 (en) 2003-01-14
ATE258166T1 (de) 2004-02-15
HK1014935A1 (en) 1999-10-08
KR100288673B1 (ko) 2001-05-02
HRP960386A2 (en) 1998-04-30
PE1398A1 (es) 1998-02-27
DE69616817T2 (de) 2002-04-04
JP3084069B2 (ja) 2000-09-04
CN1153764C (zh) 2004-06-16
TW340842B (en) 1998-09-21
HRP960386B1 (en) 2002-04-30
BG102288A (en) 1998-09-30
PT861235E (pt) 2002-03-28
WO1997008144A1 (en) 1997-03-06
EP0861235B1 (en) 2001-11-07
HUP9901159A3 (en) 2000-05-29
AP9600850A0 (en) 1996-10-31
ES2163017T3 (es) 2002-01-16
SK282925B6 (sk) 2003-01-09
PE20010700A1 (es) 2001-07-09
CZ52198A3 (cs) 1999-01-13
AP643A (en) 1998-04-24
CZ297543B6 (cs) 2007-02-07
KR19990044077A (ko) 1999-06-25
IS1947B (is) 2004-10-13
UA48981C2 (uk) 2002-09-16
JPH10510554A (ja) 1998-10-13
NO980751L (no) 1998-02-23
NO310720B1 (no) 2001-08-20
DK0861235T3 (da) 2001-12-27
OA10666A (en) 2002-11-25
NZ308207A (en) 1998-07-28
NO980751D0 (no) 1998-02-23
BG64126B1 (bg) 2004-01-30
ES2211684T3 (es) 2004-07-16
MA23961A1 (fr) 1997-04-01
DE69631390T2 (de) 2004-11-25
IL119078A (en) 2003-11-23
MX9801467A (es) 1998-05-31
IL119078A0 (en) 1996-11-14
EP1114817B1 (en) 2004-01-21
SI1114817T1 (en) 2004-06-30
IS4644A (is) 1997-12-30
PT1114817E (pt) 2004-05-31
YU47896A (sh) 1998-12-23
HU225480B1 (en) 2006-12-28
AU5776996A (en) 1997-03-19
EP1114817A1 (en) 2001-07-11
HUP9901159A2 (hu) 1999-07-28
MY114800A (en) 2003-01-31
DK1114817T3 (da) 2004-04-26
YU49122B (sh) 2004-03-12
AR006305A1 (es) 1999-08-25
DE69616817D1 (de) 2001-12-13
ATE208377T1 (de) 2001-11-15
EP0861235A1 (en) 1998-09-02
RU2152930C2 (ru) 2000-07-20
TNSN96107A1 (fr) 2005-03-15

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE PATENTE COM BASE NOS ARTIGOS 8, 11, 13 E 24 DA LPI NO 9.279/1.996.