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BG27903A3 - Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid - Google Patents

Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Info

Publication number
BG27903A3
BG27903A3 BG028038A BG2803874A BG27903A3 BG 27903 A3 BG27903 A3 BG 27903A3 BG 028038 A BG028038 A BG 028038A BG 2803874 A BG2803874 A BG 2803874A BG 27903 A3 BG27903 A3 BG 27903A3
Authority
BG
Bulgaria
Prior art keywords
morphinanes
benzomorphanes
furilmethil
methoxy
methyl
Prior art date
Application number
BG028038A
Other languages
Bulgarian (bg)
English (en)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walter
Klaus Stockbaus
Original Assignee
C.H.Boehringer Sohn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn
Publication of BG27903A3 publication Critical patent/BG27903A3/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BG028038A 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid BG27903A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732354002 DE2354002A1 (de) 1973-10-27 1973-10-27 Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
BG27903A3 true BG27903A3 (en) 1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes
BG028038A BG27903A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BG028036A BG27901A3 (bg) 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG028037A BG27902A3 (en) 1973-10-27 1974-10-25 Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes

Country Status (27)

Country Link
US (1) US3981874A (ro)
JP (1) JPS5738590B2 (ro)
AT (6) AT335076B (ro)
BE (1) BE821505A (ro)
BG (3) BG27901A3 (ro)
CA (1) CA1056377A (ro)
CH (6) CH609046A5 (ro)
CS (3) CS171195B2 (ro)
DD (1) DD115909A5 (ro)
DE (1) DE2354002A1 (ro)
DK (1) DK138325C (ro)
ES (6) ES431057A1 (ro)
FI (1) FI62079C (ro)
FR (1) FR2248838B1 (ro)
GB (1) GB1482552A (ro)
HU (1) HU176479B (ro)
IE (1) IE41528B1 (ro)
IL (1) IL45938A (ro)
NL (1) NL7413980A (ro)
NO (1) NO140859C (ro)
PH (1) PH11894A (ro)
PL (3) PL92053B1 (ro)
RO (5) RO65656A (ro)
SE (1) SE422791B (ro)
SU (6) SU510999A3 (ro)
YU (5) YU36949B (ro)
ZA (1) ZA746790B (ro)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
US8575156B2 (en) 2007-07-26 2013-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
US8859580B2 (en) 2007-11-16 2014-10-14 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5538239B2 (ja) * 2008-02-12 2014-07-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格の尿素誘導体、そのような化合物を含む医薬ならびにそれらの使用
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200946520A (en) 2008-05-01 2009-11-16 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状阻害剤
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CN102119160B (zh) 2008-07-25 2014-11-05 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) * 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 置換5、6及び7員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632591A (en) * 1968-07-19 1972-01-04 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) * 1968-12-26 1974-09-03 Sumitomo Chemical Co 2-aroylalkyl benzomorphans
CS166804B2 (ro) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim

Also Published As

Publication number Publication date
ES431054A1 (es) 1976-10-16
HU176479B (en) 1981-03-28
PL92086B1 (ro) 1977-03-31
YU285274A (en) 1982-02-25
SU512707A3 (ru) 1976-04-30
SE422791B (sv) 1982-03-29
RO65656A (ro) 1980-06-15
NO140859B (no) 1979-08-20
YU285174A (en) 1982-06-18
AT335631B (de) 1977-03-25
PL92052B1 (ro) 1977-03-31
YU36952B (en) 1984-08-31
CS171194B2 (ro) 1976-10-29
ATA829074A (de) 1976-07-15
YU36951B (en) 1984-08-31
ATA828574A (de) 1976-07-15
US3981874A (en) 1976-09-21
CH609340A5 (ro) 1979-02-28
CH609046A5 (ro) 1979-02-15
ZA746790B (en) 1976-06-30
YU36949B (en) 1984-08-31
ES431058A1 (es) 1976-10-16
CH609685A5 (ro) 1979-03-15
FI62079C (fi) 1982-11-10
NO140859C (no) 1979-11-28
YU285374A (en) 1982-06-18
SU511005A3 (ru) 1976-04-15
RO65655A (ro) 1980-06-15
CH609047A5 (ro) 1979-02-15
DD115909A5 (ro) 1975-10-20
JPS5071679A (ro) 1975-06-13
DK138325C (da) 1979-01-22
SU510999A3 (ru) 1976-04-15
BE821505A (fr) 1975-04-25
ES431056A1 (es) 1976-10-16
GB1482552A (en) 1977-08-10
SU508192A3 (ru) 1976-03-25
FI314174A (ro) 1975-04-28
IE41528L (en) 1975-04-27
DK559874A (ro) 1975-06-23
RO65658A (fr) 1979-07-15
IL45938A (en) 1977-12-30
IL45938A0 (en) 1974-12-31
FR2248838A1 (ro) 1975-05-23
RO65659A (ro) 1980-06-15
DK138325B (da) 1978-08-14
ATA828874A (de) 1976-06-15
AT335632B (de) 1977-03-25
ES431055A1 (es) 1976-10-16
NO743845L (ro) 1975-05-26
YU36519B (en) 1984-02-29
PL92053B1 (ro) 1977-03-31
IE41528B1 (en) 1980-01-30
YU285474A (en) 1982-06-18
FR2248838B1 (ro) 1977-11-04
CS171195B2 (ro) 1976-10-29
ATA828774A (de) 1976-07-15
YU36950B (en) 1984-08-31
ES431059A1 (es) 1976-10-16
DE2354002A1 (de) 1975-05-07
JPS5738590B2 (ro) 1982-08-16
CS171196B2 (ro) 1976-10-29
PH11894A (en) 1978-08-29
SU508193A3 (ru) 1976-03-25
SU578870A3 (ru) 1977-10-30
AT335633B (de) 1977-03-25
CH609686A5 (ro) 1979-03-15
BG27901A3 (bg) 1980-01-15
RO65657A (ro) 1980-06-15
NL7413980A (nl) 1975-04-29
FI62079B (fi) 1982-07-30
SE7413485L (ro) 1975-04-28
BG27902A3 (en) 1980-01-15
AT336202B (de) 1977-04-25
CA1056377A (en) 1979-06-12
ATA828974A (de) 1976-08-15
AT335076B (de) 1977-02-25
ES431057A1 (es) 1976-10-16
AT335634B (de) 1977-03-25
ATA828674A (de) 1976-07-15
YU285674A (en) 1982-06-18
CH609048A5 (ro) 1979-02-15

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