ATE230389T1 - Angiogenese inhibitoren - Google Patents

Angiogenese inhibitoren

Info

Publication number: ATE230389T1
Authority: AT; Austria
Prior art keywords: angiogenesis inhibitors; angiogenesis; inhibitors
Prior art date: 1995-10-25

Application number

AT99102501T

Other languages

English (en)

Inventor

Chiho Fukiage

Mitsuyoshi Azuma

Jun Rui Inoue

Masayuki Nakamura

Yuka Yoshida

Original Assignee

Senju Pharma Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-25

Filing date

1996-10-23

Publication date

2003-01-15

1996-10-23 Application filed by Senju Pharma Co filed Critical Senju Pharma Co

2003-01-15 Application granted granted Critical

2003-01-15 Publication of ATE230389T1 publication Critical patent/ATE230389T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT99102501T 1995-10-25 1996-10-23 Angiogenese inhibitoren ATE230389T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP27748595		1995-10-25
JP24804696		1996-09-19

Publications (1)

Publication Number	Publication Date
ATE230389T1 true ATE230389T1 (de)	2003-01-15

Family

ID=26538555

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT99102501T ATE230389T1 (de)	1995-10-25	1996-10-23	Angiogenese inhibitoren
AT96116994T ATE230275T1 (de)	1995-10-25	1996-10-23	Angiogense-inhibitor
AT99106760T ATE239698T1 (de)	1995-10-25	1996-10-23	Angiogenese hemmer

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT96116994T ATE230275T1 (de)	1995-10-25	1996-10-23	Angiogense-inhibitor
AT99106760T ATE239698T1 (de)	1995-10-25	1996-10-23	Angiogenese hemmer

Country Status (13)

Country	Link
US (2)	US6057290A (de)
EP (2)	EP0927716B1 (de)
AR (1)	AR004694A1 (de)
AT (3)	ATE230389T1 (de)
AU (1)	AU716495B2 (de)
BR (1)	BR9605267A (de)
CA (1)	CA2188817C (de)
DE (3)	DE69625575T2 (de)
ES (2)	ES2190139T3 (de)
HU (1)	HUP9602943A3 (de)
MX (1)	MX9605156A (de)
NO (1)	NO964514L (de)
PL (1)	PL316669A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR19990028948A (ko) *	1995-07-13	1999-04-15	요시다 쇼지	피페라진 유도체 및 그의 용도
US6214800B1 (en) *	1995-10-25	2001-04-10	Senju Pharmaceutical Co., Ltd.	Angiogenesis inhibitor
DE19718826A1 (de) *	1997-05-05	1998-11-12	Marion S Dr Eckmiller	Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung
EP1022276B1 (de) *	1997-09-04	2003-05-28	Nippon Chemiphar Co., Ltd.	Epoxybernsteinsäureamid-derivate
US6015787A (en) *	1997-11-04	2000-01-18	New England Medical Center Hospitals, Inc.	Cell-permeable protein inhibitors of calpain
ATE400277T1 (de)	1998-03-05	2008-07-15	Senju Pharma Co	Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten
WO1999048522A1 (en) *	1998-03-20	1999-09-30	Senju Pharmaceutical Co., Ltd.	Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment
GB9819860D0 (en) *	1998-09-12	1998-11-04	Zeneca Ltd	Chemical compounds
WO2000038717A2 (en)	1998-12-23	2000-07-06	G.D. Searle & Co.	Use of a matrix metalloproteinase inhibitor and radiation as a combined treatment of neoplasia
AU3196300A (en) *	1999-03-26	2000-10-16	Shionogi & Co., Ltd.	Carbocyclic sulfonamide derivatives
KR20010001270A (ko) *	1999-06-03	2001-01-05	복성해	혈관신생을 억제하는 새로운 이소쿠마린 유도체
EP1221315A4 (de)	1999-10-13	2007-12-12	Senju Pharma Co	Adhäsive ophthalmische zubereitungen zur perkutanen absporption
WO2001041757A1 (fr) *	1999-12-10	2001-06-14	Senju Pharmaceutical Co., Ltd.	Composition pharmaceutique contenant de la cyclodextrine
AU2001292287A1 (en) *	2000-10-26	2002-05-06	Senju Pharmaceutical Co. Ltd.	Drug composition comprising dipeptydyl aldehyde derivative
AU2002221066A1 (en) *	2000-12-12	2002-06-24	Senju Pharmaceutical Co. Ltd.	Hydrazone derivatives and use thereof in medicines
CA2446719A1 (en)	2001-06-06	2002-12-12	Eli Lilly And Company	Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents
US7115607B2 (en) *	2001-07-25	2006-10-03	Amgen Inc.	Substituted piperazinyl amides and methods of use
JPWO2003078415A1 (ja) *	2002-03-15	2005-07-14	千寿製薬株式会社	環状ヘミアセタール誘導体およびその用途
WO2003082837A1 (fr)	2002-03-29	2003-10-09	Senju Pharmaceutical Co., Ltd.	Derive de l'hydroxymorpholinone et ses utilisations medicales
EP1354586A1 (de) *	2002-04-20	2003-10-22	Aventis Pharma Deutschland GmbH	Verwendung von Hydroxypyridon Derivaten zur Wundheilung
AU2003248059A1 (en) *	2002-07-22	2004-02-09	Senju Pharmaceutical Co., Ltd.	NOVEL Alpha-KETOAMIDE DERIVATIVE AND USE THEREOF
GB0314262D0 (en)	2003-06-19	2003-07-23	Univ Nottingham Trent	Novel compounds and methods of using the same
US7615556B2 (en) *	2006-01-27	2009-11-10	Bristol-Myers Squibb Company	Piperazinyl derivatives as modulators of chemokine receptor activity
US8236798B2 (en)	2009-05-07	2012-08-07	Abbott Gmbh & Co. Kg	Carboxamide compounds and their use as calpain inhibitors
US20120065793A1 (en)	2010-02-25	2012-03-15	Kaji Mitsuru	Demand and supply control apparatus, demand and supply control method, and program
WO2012008159A1 (en)	2010-07-14	2012-01-19	Senju Pharmaceutical Co., Ltd.	Solid dispersion of alfa-ketoamide derivatives
GB201218084D0 (en) *	2012-10-09	2012-11-21	Univ Aston	Novel compounds and methods for use in medicine
GB201220474D0 (en) *	2012-11-14	2012-12-26	Sagetis Biotech Sl	Polypeptides
US20210145930A1 (en) *	2018-05-07	2021-05-20	NeuroTheranostics, Inc.	Multiple layer article with interactive reinforcements linear ribbon fiber reinforcement for composite forms
WO2022187491A1 (en) *	2021-03-03	2022-09-09	The Texas A& M University System	Inhibitors of cysteine proteases

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS50137951A (de)	1974-04-27	1975-11-01
JPS5754157A (en)	1980-09-19	1982-03-31	Nippon Kayaku Co Ltd	L-argininal derivative and its preparation
PT84170B (pt) *	1986-01-24	1989-03-30	Sanofi Sa	Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas
JP2536754B2 (ja) *	1987-05-08	1996-09-18	日本ケミファ株式会社	ピペラジン誘導体
JPH0832698B2 (ja) *	1987-05-08	1996-03-29	日本ケミファ株式会社	ピペラジン誘導体
JP2701932B2 (ja)	1989-04-10	1998-01-21	サントリー株式会社	タンパク質分解酵素阻害剤
US5510531A (en)	1989-04-10	1996-04-23	Suntory Limited	Proteinase inhibitor
DE69024400T2 (de) *	1989-04-28	1996-06-27	Takara Shuzo Co	Dem menschlichen Calpastatin ähnliches Polypeptid
ZA921279B (en)	1991-02-22	1993-08-23	Du Pont Merck Pharma	Substituted alpha-aminoaldehydes and derivatives
EP0504938A3 (en) *	1991-03-22	1993-04-14	Suntory Limited	Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
CA2071621C (en) *	1991-06-19	1996-08-06	Ahihiko Hosoda	Aldehyde derivatives
JP2848232B2 (ja)	1993-02-19	1999-01-20	武田薬品工業株式会社	アルデヒド誘導体
US5607831A (en)	1993-03-25	1997-03-04	The United States Of America As Represented By The Department Of Health And Human Services	In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death
US5658885A (en)	1993-04-27	1997-08-19	The Dupont Merck Pharmaceutical Company	Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes
JP3599287B2 (ja) *	1993-04-28	2004-12-08	三菱化学株式会社	スルホンアミド誘導体
WO1996010014A1 (en) *	1994-09-27	1996-04-04	Takeda Chemical Industries, Ltd.	Aldehyde derivatives as upsteine protease inhibitors
US5614649A (en)	1994-11-14	1997-03-25	Cephalon, Inc.	Multicatalytic protease inhibitors
EP0731107A1 (de) *	1995-02-13	1996-09-11	Takeda Chemical Industries, Ltd.	Herstellung von Aldehyd-Derivaten
EP0824543A1 (de)	1995-05-10	1998-02-25	Chiroscience Limited	Peptide, die metalloproteinasen und die tnf-freisetzung hemmen, und ihre therapeutische verwendung
KR19990028948A (ko) *	1995-07-13	1999-04-15	요시다 쇼지	피페라진 유도체 및 그의 용도
AU714324B2 (en)	1995-11-28	2000-01-06	Cephalon, Inc.	D-amino acid derived inhibitors of cysteine and serine proteases

1996
- 1996-10-23 EP EP99106760A patent/EP0927716B1/de not_active Expired - Lifetime
- 1996-10-23 AT AT99102501T patent/ATE230389T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99102501T patent/ES2190139T3/es not_active Expired - Lifetime
- 1996-10-23 ES ES99106760T patent/ES2193615T3/es not_active Expired - Lifetime
- 1996-10-23 DE DE69625575T patent/DE69625575T2/de not_active Expired - Lifetime
- 1996-10-23 EP EP96116994A patent/EP0771565B1/de not_active Expired - Lifetime
- 1996-10-23 DE DE69628050T patent/DE69628050T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT96116994T patent/ATE230275T1/de not_active IP Right Cessation
- 1996-10-23 AT AT99106760T patent/ATE239698T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69625622T patent/DE69625622T2/de not_active Expired - Lifetime
- 1996-10-24 NO NO964514A patent/NO964514L/no not_active Application Discontinuation
- 1996-10-24 CA CA2188817A patent/CA2188817C/en not_active Expired - Fee Related
- 1996-10-24 PL PL96316669A patent/PL316669A1/xx unknown
- 1996-10-24 US US08/740,069 patent/US6057290A/en not_active Expired - Lifetime
- 1996-10-24 MX MX9605156A patent/MX9605156A/es unknown
- 1996-10-24 HU HU9602943A patent/HUP9602943A3/hu unknown
- 1996-10-24 AU AU70384/96A patent/AU716495B2/en not_active Ceased
- 1996-10-25 AR ARP960104906A patent/AR004694A1/es unknown
- 1996-10-25 BR BR9605267A patent/BR9605267A/pt not_active Application Discontinuation
1999
- 1999-02-03 US US09/243,822 patent/US6551999B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0927716A1 (de)	1999-07-07
ES2193615T3 (es)	2003-11-01
EP0771565B1 (de)	2003-01-02
DE69625622T2 (de)	2003-08-14
ES2190139T3 (es)	2003-07-16
AU716495B2 (en)	2000-02-24
US6551999B1 (en)	2003-04-22
EP0771565A2 (de)	1997-05-07
DE69625575D1 (de)	2003-02-06
DE69628050T2 (de)	2004-04-01
US6057290A (en)	2000-05-02
NO964514D0 (no)	1996-10-24
HUP9602943A2 (en)	1997-08-28
DE69628050D1 (de)	2003-06-12
ATE239698T1 (de)	2003-05-15
EP0771565A3 (de)	1998-11-04
ATE230275T1 (de)	2003-01-15
BR9605267A (pt)	1998-07-21
AR004694A1 (es)	1999-03-10
HUP9602943A3 (en)	1998-03-02
NO964514L (no)	1997-04-28
CA2188817A1 (en)	1997-04-26
CA2188817C (en)	2010-01-26
MX9605156A (es)	1998-05-31
AU7038496A (en)	1997-05-01
PL316669A1 (en)	1997-04-28
EP0927716B1 (de)	2003-05-07
DE69625622D1 (de)	2003-02-06
DE69625575T2 (de)	2003-09-25

Publication	Publication Date	Title
ATE230389T1 (de)	2003-01-15	Angiogenese inhibitoren
FI963597A0 (fi)	1996-09-12	Isoprenyylitransferaasi-inhibiittoreita
NO972930D0 (no)	1997-06-23	Fibronectin-adhesjonsinhibitorer
FI972160A (fi)	1997-05-22	Matriisimetalloproteaasi-inhibiittorit
NO962381L (no)	1996-12-09	Spiss-beskytter-innretning
PT858464E (pt)	2003-08-29	Inibidores de trombina
DE59609887D1 (de)	2003-01-02	Substituierte cyanophenyluracile
NO980643D0 (no)	1998-02-16	Propylendopeptidase inhibitorer
DE59610332D1 (de)	2003-05-15	Substituierte aminouracile
PT863916E (pt)	2002-07-31	Tripeptidos de polifluoroalquil triptofano inibidores de trombina
BR9608890A (pt)	1999-06-15	N-metilenotiouréias substituídas
BR9609319A (pt)	1999-07-06	Carbonilaminofeniluracilas substituídas
BR9603376A (pt)	1998-05-12	Tetrahidro-5-nitro-pirimidinas substituídas
DE59607732D1 (de)	2001-10-25	Substituierte benzylidencyanessigester
BR9610514A (pt)	1999-03-30	Inibidores cicloantihelmínticos
DE59607958D1 (de)	2001-11-22	Substituierte phenyluracile
FI1943U1 (fi)	1995-06-09	Bomsystem till skogmaskin
KR970703937A (ko)	1997-08-09	금속단백질 분해효소 억제제(Metallproteinase inhibitors)
CY2007006I2 (el)	2009-11-04	Αναστολεις συνθεσεις απολιποπρωτεϊνης-β
NO950285D0 (no)	1995-01-26	Teletorgteknikk
BR9503278A (pt)	1996-04-30	Dispositivos absorventes bucais
FI2196U1 (fi)	1995-11-24	Snoestyrningsblad till snoeslunga
FI2002U1 (fi)	1995-07-07	Haollare till spoestaell
FI2187U1 (fi)	1995-11-21	Hoerndetalj till plaottlaoda
FI1863U1 (fi)	1995-04-19	Vaeggkonstruktion till timmerhus

Legal Events

Date	Code	Title	Description
2003-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties