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ATE269316T1 - 2-phenylpyran-4-on derivate - Google Patents

2-phenylpyran-4-on derivate

Info

Publication number
ATE269316T1
ATE269316T1 AT01927742T AT01927742T ATE269316T1 AT E269316 T1 ATE269316 T1 AT E269316T1 AT 01927742 T AT01927742 T AT 01927742T AT 01927742 T AT01927742 T AT 01927742T AT E269316 T1 ATE269316 T1 AT E269316T1
Authority
AT
Austria
Prior art keywords
phenylpyran
derivatives
Prior art date
Application number
AT01927742T
Other languages
English (en)
Inventor
Crespo Maria Isabel Crespo
Mayorga Juan Miguel Jimenez
Julia Josep Lluis Matallana
Gras Joan Feixas
Original Assignee
Almirall Prodesfarma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Ag filed Critical Almirall Prodesfarma Ag
Application granted granted Critical
Publication of ATE269316T1 publication Critical patent/ATE269316T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01927742T 2000-03-16 2001-03-16 2-phenylpyran-4-on derivate ATE269316T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200000637 2000-03-16
PCT/EP2001/003042 WO2001068633A1 (en) 2000-03-16 2001-03-16 2-phenylpyran-4-one derivatives

Publications (1)

Publication Number Publication Date
ATE269316T1 true ATE269316T1 (de) 2004-07-15

Family

ID=8492732

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01927742T ATE269316T1 (de) 2000-03-16 2001-03-16 2-phenylpyran-4-on derivate

Country Status (27)

Country Link
US (1) US7354936B2 (de)
EP (1) EP1263751B1 (de)
JP (1) JP2003527389A (de)
KR (1) KR20030005221A (de)
CN (1) CN1429221A (de)
AR (1) AR030410A1 (de)
AT (1) ATE269316T1 (de)
AU (1) AU2001254692A1 (de)
BG (1) BG107101A (de)
BR (1) BR0109252A (de)
CA (1) CA2403149A1 (de)
CZ (1) CZ20023058A3 (de)
DE (1) DE60103859T2 (de)
EE (1) EE200200528A (de)
ES (1) ES2223830T3 (de)
HK (1) HK1048117A1 (de)
HU (1) HUP0301696A2 (de)
IL (1) IL151598A0 (de)
MX (1) MXPA02009016A (de)
NO (1) NO20024393L (de)
NZ (1) NZ521187A (de)
PE (1) PE20011333A1 (de)
PL (1) PL358062A1 (de)
RU (1) RU2002127728A (de)
SK (1) SK12832002A3 (de)
WO (1) WO2001068633A1 (de)
ZA (1) ZA200207184B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465509B2 (en) * 2000-06-30 2002-10-15 Merck Frosst Canada & Co. Pyrones as inhibitors of cyclooxygenase-2
ES2213485B1 (es) 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
CN102731456B (zh) * 2011-04-01 2014-07-09 华中科技大学 一种抗肿瘤化合物及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH524613A (de) 1969-12-31 1972-06-30 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3901908A (en) 1970-12-28 1975-08-26 Ciba Geigy Corp 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles
IL59748A (en) 1979-04-05 1983-11-30 Lilly Industries Ltd 5-substituted pyranone derivatives,their production and pharmaceutical compositions containing them
US4304728A (en) 1979-04-05 1981-12-08 Lilly Industries Limited 6-Substituted pyranone compounds and their use as pharmaceuticals
US6048850A (en) 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
EP0729466A1 (de) * 1993-11-19 1996-09-04 PARKE, DAVIS & COMPANY Pyron derivate als protease inhibitoren und antivirusmittel
US5521213A (en) 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5541204A (en) 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
EP0819127A1 (de) 1995-04-04 1998-01-21 Glaxo Group Limited IMIDAZO[1,2-a]PYRIDINDERIVATE
CN1142148C (zh) 1997-11-19 2004-03-17 兴和株式会社 新颖的哒嗪衍生物和含有其作为有效成分的药物
TW587079B (en) * 1998-09-25 2004-05-11 Almirall Prodesfarma Ag 2-phenylpyran-4-one derivatives

Also Published As

Publication number Publication date
CA2403149A1 (en) 2001-09-20
CZ20023058A3 (cs) 2004-01-14
CN1429221A (zh) 2003-07-09
NZ521187A (en) 2004-03-26
ZA200207184B (en) 2003-12-08
NO20024393D0 (no) 2002-09-13
PE20011333A1 (es) 2002-01-16
AU2001254692A1 (en) 2001-09-24
IL151598A0 (en) 2003-04-10
EP1263751B1 (de) 2004-06-16
EE200200528A (et) 2004-04-15
HK1048117A1 (zh) 2003-03-21
AR030410A1 (es) 2003-08-20
EP1263751A1 (de) 2002-12-11
RU2002127728A (ru) 2004-03-20
KR20030005221A (ko) 2003-01-17
JP2003527389A (ja) 2003-09-16
PL358062A1 (en) 2004-08-09
ES2223830T3 (es) 2005-03-01
US20030232880A1 (en) 2003-12-18
BG107101A (bg) 2003-07-31
DE60103859T2 (de) 2005-07-21
NO20024393L (no) 2002-11-13
MXPA02009016A (es) 2004-10-15
SK12832002A3 (sk) 2003-11-04
US7354936B2 (en) 2008-04-08
HUP0301696A2 (hu) 2003-09-29
WO2001068633A1 (en) 2001-09-20
DE60103859D1 (de) 2004-07-22
BR0109252A (pt) 2002-12-24

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties