AR212176A1 - Procedimiento para preparar derivados de(4-hidroxipirrolidin-2-on-il)acilamida - Google Patents
Procedimiento para preparar derivados de(4-hidroxipirrolidin-2-on-il)acilamidaInfo
- Publication number
- AR212176A1 AR212176A1 AR264270A AR26427076A AR212176A1 AR 212176 A1 AR212176 A1 AR 212176A1 AR 264270 A AR264270 A AR 264270A AR 26427076 A AR26427076 A AR 26427076A AR 212176 A1 AR212176 A1 AR 212176A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydroxypyrrolidin
- preparing
- procedure
- acylamide derivatives
- acylamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT26326/75A IT1045043B (it) | 1975-08-13 | 1975-08-13 | Derivati pirrolidinici |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR212176A1 true AR212176A1 (es) | 1978-05-31 |
Family
ID=11219233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR264270A AR212176A1 (es) | 1975-08-13 | 1976-08-09 | Procedimiento para preparar derivados de(4-hidroxipirrolidin-2-on-il)acilamida |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4118396A (es) |
| JP (1) | JPS5822034B2 (es) |
| AR (1) | AR212176A1 (es) |
| AT (1) | AT353783B (es) |
| AU (1) | AU506651B2 (es) |
| BE (1) | BE845099A (es) |
| CA (1) | CA1077947A (es) |
| CH (1) | CH624935A5 (es) |
| CS (1) | CS214766B2 (es) |
| DD (1) | DD127966B3 (es) |
| DE (1) | DE2635853C2 (es) |
| DK (1) | DK156055C (es) |
| ES (1) | ES450643A1 (es) |
| FI (1) | FI62290C (es) |
| FR (1) | FR2320741A1 (es) |
| GB (1) | GB1550160A (es) |
| HU (1) | HU173742B (es) |
| IN (1) | IN144871B (es) |
| IT (1) | IT1045043B (es) |
| MX (1) | MX4717E (es) |
| NL (1) | NL179052C (es) |
| NO (1) | NO146909C (es) |
| NZ (1) | NZ181726A (es) |
| PL (1) | PL101471B1 (es) |
| SE (1) | SE420599B (es) |
| SU (1) | SU663302A3 (es) |
| YU (1) | YU40147B (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1075280B (it) * | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| IT1075564B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| GB1580559A (en) * | 1977-11-24 | 1980-12-03 | Wyeth John & Brother Ltd | Amide cerivatives |
| IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
| NL8004025A (nl) * | 1979-08-09 | 1981-02-11 | Hoffmann La Roche | Pyrrolidinederivaten en werkwijze voor het bereiden daarvan alsmede geneesmiddel. |
| CH646149A5 (de) * | 1981-02-05 | 1984-11-15 | Hoffmann La Roche | Pyrrolidin-derivat. |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
| CH666483A5 (de) * | 1985-01-16 | 1988-07-29 | Lonza Ag | Verfahren zur herstellung von thiotetronsaeure. |
| IT1190378B (it) * | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| EP0223328B1 (en) | 1985-07-26 | 1992-01-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Process for producing oxiracetam |
| HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
| IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
| CH668423A5 (de) * | 1986-06-19 | 1988-12-30 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen. |
| US4677114A (en) * | 1985-11-22 | 1987-06-30 | Warner-Lambert Company | Pyrrolidone-2 derivatives and pharmaceutical compositions thereof |
| CH668424A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung. |
| CH668422A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure. |
| IT1224168B (it) * | 1986-08-01 | 1990-09-26 | Finanziaria R F Spa Ora Finanz | Derivati del pirrolidin-2-one ad attivita' nootropa |
| CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
| CH670644A5 (es) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
| US5202345A (en) * | 1987-08-19 | 1993-04-13 | Shionogi & Co., Ltd. | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
| JP2660201B2 (ja) * | 1988-08-05 | 1997-10-08 | 塩野義製薬株式会社 | 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬 |
| DE58909320D1 (de) * | 1988-09-06 | 1995-08-03 | Lonza Ag | Verfahren zur Herstellung von 5-Alkyltetramsäuren. |
| AU625157B2 (en) * | 1989-01-17 | 1992-07-02 | F. Hoffmann-La Roche Ag | Cyclohexaneacetamide derivatives |
| FI95034C (fi) * | 1989-03-15 | 1995-12-11 | Lonza Ag | Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi |
| CH680293A5 (es) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| JP3038032B2 (ja) * | 1991-03-25 | 2000-05-08 | 日清製粉株式会社 | 血小板凝集抑制薬 |
| CN1484527A (zh) | 2000-12-28 | 2004-03-24 | ��һ��������ҩ��ʽ���� | 神经性疼痛治疗和预防药 |
| WO2007065634A1 (en) * | 2005-12-07 | 2007-06-14 | Ucb Pharma, S.A. | 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses |
| DK3260118T3 (da) | 2008-10-16 | 2021-04-19 | Univ Johns Hopkins | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| JP6082250B2 (ja) * | 2010-02-09 | 2017-02-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 認知機能を改善するための方法および組成物 |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| WO2014144801A1 (en) | 2013-03-15 | 2014-09-18 | Agenebio Inc. | Methods and compositions for improving cognitive function |
| CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
| CN105820102A (zh) * | 2016-05-10 | 2016-08-03 | 武汉工程大学 | 奥拉西坦的合成工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1011886B (de) * | 1952-04-29 | 1957-07-11 | Waldemar Kutscher Dr Ing Dr Me | Verfahren zur Herstellung von Aminoalkylpyrrolen |
| GB1309692A (en) * | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
| GB1039113A (en) * | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
| US3541111A (en) * | 1968-05-08 | 1970-11-17 | Du Pont | Pyrrolinecarboxanilide compounds |
| US3577432A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-phenoxypyrrolidines |
-
1975
- 1975-08-13 IT IT26326/75A patent/IT1045043B/it active Protection Beyond IP Right Term
-
1976
- 1976-08-09 CS CS765174A patent/CS214766B2/cs unknown
- 1976-08-09 CA CA258,677A patent/CA1077947A/en not_active Expired
- 1976-08-09 AT AT589476A patent/AT353783B/de active
- 1976-08-09 IN IN1433/CAL/1976A patent/IN144871B/en unknown
- 1976-08-09 AR AR264270A patent/AR212176A1/es active
- 1976-08-09 NZ NZ181726A patent/NZ181726A/xx unknown
- 1976-08-10 YU YU1964/76A patent/YU40147B/xx unknown
- 1976-08-10 HU HU76IE754A patent/HU173742B/hu not_active IP Right Cessation
- 1976-08-10 SE SE7608938A patent/SE420599B/xx not_active IP Right Cessation
- 1976-08-10 GB GB33243/76A patent/GB1550160A/en not_active Expired
- 1976-08-10 DE DE2635853A patent/DE2635853C2/de not_active Expired
- 1976-08-11 JP JP51095930A patent/JPS5822034B2/ja not_active Expired
- 1976-08-11 FR FR7624482A patent/FR2320741A1/fr active Granted
- 1976-08-11 CH CH1022576A patent/CH624935A5/de not_active IP Right Cessation
- 1976-08-11 BE BE6045634A patent/BE845099A/xx not_active IP Right Cessation
- 1976-08-11 NO NO762791A patent/NO146909C/no unknown
- 1976-08-11 NL NLAANVRAGE7608946,A patent/NL179052C/xx not_active IP Right Cessation
- 1976-08-11 DD DD19428776A patent/DD127966B3/de unknown
- 1976-08-12 FI FI762314A patent/FI62290C/fi not_active IP Right Cessation
- 1976-08-12 DK DK365176A patent/DK156055C/da not_active IP Right Cessation
- 1976-08-12 US US05/713,901 patent/US4118396A/en not_active Expired - Lifetime
- 1976-08-12 PL PL1976191773A patent/PL101471B1/pl unknown
- 1976-08-12 SU SU762388323A patent/SU663302A3/ru active
- 1976-08-12 ES ES450643A patent/ES450643A1/es not_active Expired
- 1976-08-12 AU AU16797/76A patent/AU506651B2/en not_active Expired
- 1976-08-13 MX MX762906U patent/MX4717E/es unknown
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