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NO20070339L - 1-aza-bicyklo[3 3.1]nonaner - Google Patents

1-aza-bicyklo[3 3.1]nonaner

Info

Publication number
NO20070339L
NO20070339L NO20070339A NO20070339A NO20070339L NO 20070339 L NO20070339 L NO 20070339L NO 20070339 A NO20070339 A NO 20070339A NO 20070339 A NO20070339 A NO 20070339A NO 20070339 L NO20070339 L NO 20070339L
Authority
NO
Norway
Prior art keywords
aza
nonanes
bicyclo
pharmaceuticals
substituents
Prior art date
Application number
NO20070339A
Other languages
English (en)
Inventor
Thomas J Troxler
Dominik Feuerbach
Werner Mueller
Bernard Lucien Roy
Konstanze Hurth
Mathias Frederiksen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20070339L publication Critical patent/NO20070339L/no

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P25/32—Alcohol-abuse
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    • A61P27/00—Drugs for disorders of the senses
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
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  • Gynecology & Obstetrics (AREA)
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  • Vascular Medicine (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen angår 1-aza-bisykloalkylderivater med formelen (I) der substituentene er som definert i spesifikasjonen, fremgangsmåte for deres produksjon, deres anvendelse som legemidler og til farmasøytiske sammensetninger som omfatter dem.
NO20070339A 2004-06-18 2007-01-18 1-aza-bicyklo[3 3.1]nonaner NO20070339L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58102004P 2004-06-18 2004-06-18
PCT/EP2005/006566 WO2005123732A1 (en) 2004-06-18 2005-06-17 1-aza-bicyclo[3.3.1]nonanes

Publications (1)

Publication Number Publication Date
NO20070339L true NO20070339L (no) 2007-03-19

Family

ID=35045272

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070339A NO20070339L (no) 2004-06-18 2007-01-18 1-aza-bicyklo[3 3.1]nonaner

Country Status (32)

Country Link
US (3) US20070249657A1 (no)
EP (2) EP2336129A1 (no)
JP (1) JP4944772B2 (no)
KR (3) KR20120047317A (no)
CN (1) CN1964968A (no)
AR (1) AR049401A1 (no)
AT (1) ATE506362T1 (no)
AU (1) AU2005254689B2 (no)
BR (1) BRPI0510940A (no)
CA (1) CA2566155C (no)
CY (1) CY1111528T1 (no)
DE (1) DE602005027567D1 (no)
DK (1) DK1761533T3 (no)
EC (1) ECSP067053A (no)
ES (1) ES2364971T3 (no)
HR (1) HRP20110535T1 (no)
IL (2) IL179611A (no)
MA (1) MA28684B1 (no)
MX (1) MXPA06014697A (no)
MY (1) MY147262A (no)
NO (1) NO20070339L (no)
NZ (1) NZ551198A (no)
PE (1) PE20060437A1 (no)
PL (1) PL1761533T3 (no)
PT (1) PT1761533E (no)
RU (1) RU2445313C2 (no)
SG (1) SG153834A1 (no)
SI (1) SI1761533T1 (no)
TN (1) TNSN06407A1 (no)
TW (1) TWI370128B (no)
WO (1) WO2005123732A1 (no)
ZA (1) ZA200609255B (no)

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GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
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EP2768507B1 (en) 2011-10-20 2019-12-11 Novartis AG Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment
HK1208356A1 (en) * 2012-05-08 2016-03-04 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
US9458137B2 (en) * 2012-11-05 2016-10-04 Nantbioscience, Inc. Substituted indol-5-ol derivatives and their therapeutical applications
ES2661050T3 (es) 2012-12-11 2018-03-27 Novartis Ag Biomarcador predictivo de la capacidad de respuesta a tratamiento con activador del receptor nicotínico de acetilcolina alfa-7
WO2014111751A1 (en) 2013-01-15 2014-07-24 Novartis Ag Use of alpha 7 nicotinic receptor agonists for the treatment of narcolepsy
EP2945637B1 (en) * 2013-01-15 2021-03-10 Novartis AG Use of alpha 7 nicotinic acetylcholine receptor agonists
EP2945633B1 (en) * 2013-01-15 2021-06-30 Novartis AG Use of alpha 7 nicotinic acetylcholine receptor agonists
US20150313884A1 (en) 2013-01-15 2015-11-05 Novartis Ag Use of alpha 7 nicotinic acetylcholine receptor agonists
KR102636384B1 (ko) 2017-08-04 2024-02-14 스카이호크 테라퓨틱스, 인코포레이티드 스플라이싱을 조절하는 방법 및 조성물
KR20210135241A (ko) 2019-02-05 2021-11-12 스카이호크 테라퓨틱스, 인코포레이티드 스플라이싱을 조절하는 방법 및 조성물
JP7603595B2 (ja) 2019-02-06 2024-12-20 スカイホーク・セラピューティクス・インコーポレーテッド スプライシングを調節するための方法および組成物

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