NO20022531D0 - Vaccine for the prevention and treatment of Alzheimer's and amyloid-related diseases - Google Patents
Vaccine for the prevention and treatment of Alzheimer's and amyloid-related diseasesInfo
- Publication number
- NO20022531D0 NO20022531D0 NO20022531A NO20022531A NO20022531D0 NO 20022531 D0 NO20022531 D0 NO 20022531D0 NO 20022531 A NO20022531 A NO 20022531A NO 20022531 A NO20022531 A NO 20022531A NO 20022531 D0 NO20022531 D0 NO 20022531D0
- Authority
- NO
- Norway
- Prior art keywords
- amyloid
- alzheimer
- vaccine
- prevention
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16859499P | 1999-11-29 | 1999-11-29 | |
US72484200A | 2000-11-28 | 2000-11-28 | |
PCT/CA2000/001413 WO2001039796A2 (en) | 1999-11-29 | 2000-11-29 | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20022531D0 true NO20022531D0 (en) | 2002-05-28 |
NO20022531L NO20022531L (en) | 2002-07-12 |
Family
ID=26864284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20022531A NO20022531L (en) | 1999-11-29 | 2002-05-28 | Vaccine for the prevention and treatment of Alzheimer's and amyloid-related diseases |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1235587A2 (en) |
JP (1) | JP2004500354A (en) |
KR (2) | KR20080059676A (en) |
CN (1) | CN1433321A (en) |
AU (1) | AU784312B2 (en) |
BR (1) | BR0016022A (en) |
CA (1) | CA2388559A1 (en) |
HK (1) | HK1049279A1 (en) |
IL (1) | IL149924A0 (en) |
MX (1) | MXPA02005576A (en) |
NO (1) | NO20022531L (en) |
NZ (1) | NZ540564A (en) |
WO (1) | WO2001039796A2 (en) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US6743427B1 (en) | 1997-12-02 | 2004-06-01 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
CA2400838C (en) * | 2000-02-21 | 2013-04-23 | Pharmexa A/S | Novel method for down-regulation of amyloid |
EP2082749A3 (en) | 2000-07-07 | 2010-06-30 | Bioarctic Neuroscience AB | Prevention and treatment of Alzheimer's disease |
AU2007200047B2 (en) * | 2000-07-07 | 2009-11-26 | Bioarctic Neuroscience Ab | Prevention and treatment of Alzheimer's disease |
US20020115717A1 (en) * | 2000-07-25 | 2002-08-22 | Francine Gervais | Amyloid targeting imaging agents and uses thereof |
US7311893B2 (en) | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
MY144532A (en) | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
AR038568A1 (en) * | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | ANTI-A BETA ANTIBODIES AND ITS USE |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
CA2491611A1 (en) * | 2002-07-03 | 2004-01-15 | Bio Science International, Inc. | Peptides comprising aromatic d-amino acids and methods of use |
DE10303974A1 (en) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid β (1-42) oligomers, process for their preparation and their use |
US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
MXPA05013977A (en) * | 2003-06-23 | 2006-03-09 | Neurochem Int Ltd | Methods and compositions for treating amyloid-related diseases. |
DK2336147T3 (en) * | 2003-12-17 | 2014-06-10 | Wyeth Llc | BETA-IMMUNOGEN-PEPTIDE CARRIER CONJUGATES AND PROCEDURES FOR PRODUCING THEREOF |
SE0401601D0 (en) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
WO2006066089A1 (en) | 2004-12-15 | 2006-06-22 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
JP5145537B2 (en) | 2004-12-22 | 2013-02-20 | ビーエイチアイ リミテッド パートナーシップ | Methods and compositions for treating amyloid-related diseases |
KR100851035B1 (en) | 2005-08-23 | 2008-08-11 | 대한민국 | - - Pharmaceutical composition and composition for screening therapeutics to preventing and treating of -amyloid accumulation in brain comprising GCP-Glutamate carboxypeptidase- as an active ingredient method for screening using said composition |
JP2009516654A (en) | 2005-11-10 | 2009-04-23 | ロスキャンプ リサーチ, エルエルシー | Regulation of angiogenesis by A-beta peptide |
KR101667623B1 (en) | 2005-11-30 | 2016-10-19 | 애브비 인코포레이티드 | Monoclonal antibodies against amyloid beta protein and uses thereof |
ES2527661T3 (en) | 2005-11-30 | 2015-01-28 | Abbvie Inc. | Scanning method, process for purifying non-spreadable Abeta oligomers, selective antibodies against said spreadable Abeta oligomers and a process for making said antibodies |
NO346105B1 (en) | 2005-12-12 | 2022-02-21 | E Hoffmann La Roche Ag | AMYLOID-BETA-4 ANTIBODIES WITH GLYCOSYLATED ASPARAGIN IN THE VARIABLE REGION |
KR101236611B1 (en) * | 2005-12-12 | 2013-03-04 | 에이씨 이뮨 에스.에이. | Therapeutic vaccine |
EP2004688B2 (en) | 2006-03-23 | 2014-03-05 | BioArtic Neuroscience AB | Improved protofibril selective antibodies and the use thereof |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
ME01758B (en) * | 2006-07-14 | 2014-09-20 | Genentech Inc | Humanized antibody against amyloid beta |
EP2468770B1 (en) | 2006-07-14 | 2017-12-20 | AC Immune S.A. | Humanized antibody against amyloid beta. |
BRPI0719763A2 (en) * | 2006-10-02 | 2014-01-28 | Ac Immune Sa | ANTIBODY, NUCLEIC ACID MOLECULE, EXPRESSION VECTOR, CELL, COMPOSITION, MIXTURE, USE OF A CHEMICAL ANTIBODY OR A FRAGMENT OF THE SAME OR A FRAGMENT OF THE SAME AND / OR A PART OR A FUNCTION OR A PART OR A FUNCTION MIXTURE, METHODS FOR PREPARING A PHARMACEUTICAL COMPOSITION OR MIXTURE, TO PREVENT, TREAT OR RELIEVE THE EFFECTS OF A DISEASE, DIAGNOSTIC DISEASE, OR CONDITION ASSOCIATED WITH A DETERMINATION OF THE DETERMINATION OF CAROGUE DETERMINATION IN A FABRIC AND / OR BODY FLUIDS, TEST KITS FOR DISEASE AND DIAGNOSTIC TESTING AND CONDITIONS ASSOCIATED WITH AMYLOID, LIGHT CHAIN VARIABLE REGION, HEAVY CIRCLE, GENELE DESENGER, GENELE DIAGET LINES PRE-FORMED BETA-AMYLOID FIBERS TO PREVENT ABETA-INDUCED NEURON DEGRADATION, TO DIAGNOSE A PREDISPOSITION TO A DISEASE OR CO NDITION ASSOCIATED WITH AMYLOID IN A PATIENT, TO MONITOR MINIMUM RESIDUAL DISEASE IN A PATIENT, TO PROGNOSE LIABILITY OF A PATIENT WHO IS TREATED WITH AN ANTIBODY OR A COMPOSITION OF VACCINE, TO REDUCE THE CARBON LOAD TO THE CIRCLE THE NUMBER OF PLATES IN AN ANIMAL BRAIN, TO REDUCE THE TOTAL SOLUBLE OPEN QUANTITY IN AN ANIMAL BRAIN AND TO HOLD OR INCREASE COGNITIVE MEMORY CAPACITY IN A MAMMALIAN. |
ES2533463T3 (en) | 2006-10-12 | 2015-04-10 | Bhi Limited Partnership | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
US8106015B2 (en) | 2007-04-20 | 2012-01-31 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Method for enhancing immune response with peptide |
JP2010528583A (en) * | 2007-06-11 | 2010-08-26 | エーシー イミューン ソシエテ アノニム | Humanized antibody against amyloid β |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
JP5889529B2 (en) | 2007-07-27 | 2016-03-22 | ヤンセン・サイエンシズ・アイルランド・ユーシー | Treatment of amyloidogenic diseases |
EP2586795B1 (en) | 2007-10-05 | 2018-05-16 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
JO3076B1 (en) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | Immunotherapy regimes dependent on apoe status |
WO2009143489A2 (en) * | 2008-05-22 | 2009-11-26 | Archer Pharmaceuticals, Inc. | Modulation of angiogenesis by a-beta peptide fragments |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
EP2273273A1 (en) * | 2009-07-11 | 2011-01-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | Inhibitors of the nitration of amyloid ß peptides and their uses in the diagnosis and treatment of alzheimer's disease |
CN102933601B (en) | 2010-04-15 | 2016-06-08 | Abbvie公司 | Amyloid beta binding proteins |
WO2012016173A2 (en) | 2010-07-30 | 2012-02-02 | Ac Immune S.A. | Safe and functional humanized antibodies |
CN103298833B (en) | 2010-08-14 | 2015-12-16 | Abbvie公司 | Amyloid beta associated proteins |
PL3166970T3 (en) | 2014-07-10 | 2021-09-13 | Bioarctic Ab | Improved a-beta protofibril binding antibodies |
MY180297A (en) | 2015-06-24 | 2020-11-27 | Hoffmann La Roche | Anti-transferrin receptor antibodies with tailored affinity |
RU2753390C1 (en) | 2015-10-02 | 2021-08-13 | Ф. Хоффманн-Ля Рош Аг | Bispecific antibodies to human cd20/human transferrin receptor and methods for their use |
AR106189A1 (en) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | BIESPECTIFIC ANTIBODIES AGAINST HUMAN A-b AND THE HUMAN TRANSFERRINE RECEIVER AND METHODS OF USE |
CN108350052A (en) | 2015-11-09 | 2018-07-31 | 英属哥伦比亚大学 | Epitope in amyloid beta intermediate region and its conformation antibodies selective |
EP3374383A4 (en) | 2015-11-09 | 2019-05-15 | The University Of British Columbia | Amyloid beta epitopes and antibodies thereto |
CN109476729A (en) | 2016-07-18 | 2019-03-15 | 英属哥伦比亚大学 | The antibody of amyloid beta |
US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2245003T3 (en) * | 1996-08-27 | 2005-12-16 | Praecis Pharmaceuticals Incorporated | MODULATORS OF THE AGGREGATION OF BETA-AMYLOOID PEPTIDES THAT INCLUDE D-AMINO ACIDS. |
NO314086B1 (en) * | 1998-05-08 | 2003-01-27 | Gemvax As | Peptides and pharmaceutical compositions containing them, nucleic acid sequences encoding such peptides, plasmids and virus vectors encompassing such DNA sequences and their use for the preparation of pharmaceutical preparations for |
AU4529800A (en) * | 1999-05-05 | 2000-11-21 | Neurochem, Inc. | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
-
2000
- 2000-11-29 CN CN00816414A patent/CN1433321A/en active Pending
- 2000-11-29 JP JP2001541528A patent/JP2004500354A/en active Pending
- 2000-11-29 KR KR1020087013848A patent/KR20080059676A/en not_active Application Discontinuation
- 2000-11-29 CA CA002388559A patent/CA2388559A1/en not_active Abandoned
- 2000-11-29 NZ NZ540564A patent/NZ540564A/en unknown
- 2000-11-29 WO PCT/CA2000/001413 patent/WO2001039796A2/en active Application Filing
- 2000-11-29 EP EP00981111A patent/EP1235587A2/en not_active Withdrawn
- 2000-11-29 MX MXPA02005576A patent/MXPA02005576A/en not_active Application Discontinuation
- 2000-11-29 BR BR0016022-9A patent/BR0016022A/en not_active Application Discontinuation
- 2000-11-29 KR KR1020027006845A patent/KR20020073341A/en not_active Application Discontinuation
- 2000-11-29 IL IL14992400A patent/IL149924A0/en unknown
- 2000-11-29 AU AU18473/01A patent/AU784312B2/en not_active Ceased
-
2002
- 2002-05-28 NO NO20022531A patent/NO20022531L/en not_active Application Discontinuation
-
2003
- 2003-01-16 HK HK03100407.4A patent/HK1049279A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001039796A2 (en) | 2001-06-07 |
JP2004500354A (en) | 2004-01-08 |
HK1049279A1 (en) | 2003-05-09 |
AU1847301A (en) | 2001-06-12 |
WO2001039796A3 (en) | 2001-12-06 |
EP1235587A2 (en) | 2002-09-04 |
MXPA02005576A (en) | 2002-12-13 |
CA2388559A1 (en) | 2001-06-07 |
NZ540564A (en) | 2007-04-27 |
IL149924A0 (en) | 2002-11-10 |
CN1433321A (en) | 2003-07-30 |
KR20080059676A (en) | 2008-06-30 |
NO20022531L (en) | 2002-07-12 |
AU784312B2 (en) | 2006-03-09 |
KR20020073341A (en) | 2002-09-23 |
BR0016022A (en) | 2002-08-06 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |