MX349489B - Proceso para la preparación de moduladores del receptor h3 de histamina. - Google Patents
Proceso para la preparación de moduladores del receptor h3 de histamina.Info
- Publication number
- MX349489B MX349489B MX2016007228A MX2016007228A MX349489B MX 349489 B MX349489 B MX 349489B MX 2016007228 A MX2016007228 A MX 2016007228A MX 2016007228 A MX2016007228 A MX 2016007228A MX 349489 B MX349489 B MX 349489B
- Authority
- MX
- Mexico
- Prior art keywords
- histamine
- preparation
- receptor modulators
- disorders
- directed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La presente invención se refiere a procesos nuevos para la preparación de moduladores del receptor H3 de histamina, en el tratamiento de, por ejemplo, trastornos cognitivos, trastornos del sueño y / o trastornos siquiátricos. (Ver Fórmula).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16117709P | 2009-03-18 | 2009-03-18 | |
| PCT/US2010/027638 WO2010107897A2 (en) | 2009-03-18 | 2010-03-17 | Process for the preparation of histamine h3 receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX349489B true MX349489B (es) | 2017-07-31 |
Family
ID=42315639
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011009784A MX2011009784A (es) | 2009-03-18 | 2010-03-17 | Proceso para la preparacion de moduladores del receptor h3 de histamina. |
| MX2016007228A MX349489B (es) | 2009-03-18 | 2010-03-17 | Proceso para la preparación de moduladores del receptor h3 de histamina. |
| MX2014015305A MX347775B (es) | 2009-03-18 | 2010-03-17 | Proceso para la preparacion de moduladores del receptor h3 de histamina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011009784A MX2011009784A (es) | 2009-03-18 | 2010-03-17 | Proceso para la preparacion de moduladores del receptor h3 de histamina. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014015305A MX347775B (es) | 2009-03-18 | 2010-03-17 | Proceso para la preparacion de moduladores del receptor h3 de histamina. |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US8748596B2 (es) |
| EP (3) | EP2429996B1 (es) |
| JP (1) | JP5642149B2 (es) |
| CN (1) | CN102428070B (es) |
| AU (1) | AU2010226711B2 (es) |
| CA (2) | CA2755335C (es) |
| CY (2) | CY1119437T1 (es) |
| DK (2) | DK3216784T3 (es) |
| ES (2) | ES2625261T3 (es) |
| HR (2) | HRP20170776T1 (es) |
| HU (2) | HUE032345T2 (es) |
| LT (2) | LT3216784T (es) |
| MX (3) | MX2011009784A (es) |
| PL (2) | PL3216784T3 (es) |
| PT (2) | PT2429996T (es) |
| SI (2) | SI3216784T1 (es) |
| TR (1) | TR201902858T4 (es) |
| WO (1) | WO2010107897A2 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3216784T (lt) | 2009-03-18 | 2019-03-25 | Janssen Pharmaceutica Nv | Histamino h3 receptoriaus moduliatorių gamybos būdas |
| KR101427221B1 (ko) * | 2012-08-29 | 2014-08-13 | 주식회사 에스텍파마 | 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법 |
| CN104447867B (zh) * | 2013-09-17 | 2017-12-26 | 江苏天士力帝益药业有限公司 | 一种噻吩并哌啶衍生物、制备方法及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5724346B2 (es) * | 1973-06-22 | 1982-05-24 | ||
| NZ539595A (en) * | 2002-10-23 | 2008-02-29 | Janssen Pharmaceutica Nv | Piperazinyl and diazapanyl benzamides and benzthioamides |
| EA015555B1 (ru) | 2006-05-30 | 2011-08-30 | Янссен Фармацевтика Н.В. | Замещенные пиридиламидные соединения в качестве модуляторов гистаминового h-рецептора |
| MY158253A (en) | 2007-11-20 | 2016-09-30 | Janssen Pharmaceutica Nv | Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine h3 receptor |
| LT3216784T (lt) | 2009-03-18 | 2019-03-25 | Janssen Pharmaceutica Nv | Histamino h3 receptoriaus moduliatorių gamybos būdas |
-
2010
- 2010-03-17 LT LTEP17151754.3T patent/LT3216784T/lt unknown
- 2010-03-17 CA CA2755335A patent/CA2755335C/en active Active
- 2010-03-17 HU HUE10722449A patent/HUE032345T2/en unknown
- 2010-03-17 ES ES10722449.5T patent/ES2625261T3/es active Active
- 2010-03-17 ES ES17151754T patent/ES2714852T3/es active Active
- 2010-03-17 EP EP10722449.5A patent/EP2429996B1/en active Active
- 2010-03-17 HU HUE17151754 patent/HUE044837T2/hu unknown
- 2010-03-17 PT PT107224495T patent/PT2429996T/pt unknown
- 2010-03-17 MX MX2011009784A patent/MX2011009784A/es active IP Right Grant
- 2010-03-17 LT LTEP10722449.5T patent/LT2429996T/lt unknown
- 2010-03-17 PL PL17151754T patent/PL3216784T3/pl unknown
- 2010-03-17 MX MX2016007228A patent/MX349489B/es unknown
- 2010-03-17 CN CN201080022339.1A patent/CN102428070B/zh active Active
- 2010-03-17 SI SI201031867T patent/SI3216784T1/sl unknown
- 2010-03-17 CA CA2965059A patent/CA2965059C/en active Active
- 2010-03-17 EP EP17151754.3A patent/EP3216784B1/en active Active
- 2010-03-17 WO PCT/US2010/027638 patent/WO2010107897A2/en active Application Filing
- 2010-03-17 AU AU2010226711A patent/AU2010226711B2/en not_active Ceased
- 2010-03-17 PL PL10722449T patent/PL2429996T3/pl unknown
- 2010-03-17 TR TR2019/02858T patent/TR201902858T4/tr unknown
- 2010-03-17 MX MX2014015305A patent/MX347775B/es unknown
- 2010-03-17 EP EP18194673.2A patent/EP3492451B1/en active Active
- 2010-03-17 PT PT17151754T patent/PT3216784T/pt unknown
- 2010-03-17 DK DK17151754.3T patent/DK3216784T3/en active
- 2010-03-17 SI SI201031474T patent/SI2429996T1/sl unknown
- 2010-03-17 JP JP2012500921A patent/JP5642149B2/ja active Active
- 2010-03-17 US US13/257,224 patent/US8748596B2/en active Active
- 2010-03-17 DK DK10722449.5T patent/DK2429996T3/da active
-
2014
- 2014-04-25 US US14/261,713 patent/US9518021B2/en active Active
-
2016
- 2016-11-11 US US15/349,521 patent/US9809547B2/en active Active
-
2017
- 2017-05-24 HR HRP20170776TT patent/HRP20170776T1/hr unknown
- 2017-05-26 CY CY20171100547T patent/CY1119437T1/el unknown
- 2017-10-04 US US15/724,711 patent/US10323002B2/en active Active
-
2019
- 2019-03-11 HR HRP20190476TT patent/HRP20190476T1/hr unknown
- 2019-03-12 CY CY20191100292T patent/CY1121556T1/el unknown
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