Mattingly, 2014 - Google Patents
Aminooxy reagents in nanomedicine and bioanalysis.Mattingly, 2014
View PDF- Document ID
- 3229371067571588692
- Author
- Mattingly S
- Publication year
External Links
Snippet
The development of nanomaterials as medical diagnostic and therapeutic agents is a rapidly expanding field. A brief search of the literature revealed that roughly half of all articles related to nanoparticle-based drug delivery were published after the onset of this thesis …
- 239000003153 chemical reaction reagent 0 title abstract description 63
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48769—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form
- A61K47/48853—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere
- A61K47/48861—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere the form being an inorganic particle, e.g. a ceramic particle, silica particle, ferrite, synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48007—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the pharmacologically- or therapeutically-active agent being covalently bound or complexed to a modifying agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Fusco et al. | Graphene and other 2D materials: a multidisciplinary analysis to uncover the hidden potential as cancer theranostics | |
US9486480B2 (en) | Surface-modified heavy metal nanoparticles, compositions and uses thereof | |
Mandriota et al. | Design and application of cisplatin-loaded magnetic nanoparticle clusters for smart chemotherapy | |
Sánchez et al. | Hybrid decorated core@ shell janus nanoparticles as a flexible platform for targeted multimodal molecular bioimaging of cancer | |
Huang et al. | Curcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration | |
Li et al. | Au@ MnS@ ZnS core/shell/shell nanoparticles for magnetic resonance imaging and enhanced cancer radiation therapy | |
Alvarez-Berríos et al. | In vitro evaluation of folic acid-conjugated redox-responsive mesoporous silica nanoparticles for the delivery of cisplatin | |
Ciofani et al. | Transferrin-conjugated boron nitride nanotubes: protein grafting, characterization, and interaction with human endothelial cells | |
Das et al. | “Clickable”, trifunctional magnetite nanoparticles and their chemoselective biofunctionalization | |
Topel et al. | Synthesis and characterization of Bodipy functionalized magnetic iron oxide nanoparticles for potential bioimaging applications | |
Ozgur et al. | Synthesis and biological evaluation of radiolabeled photosensitizer linked bovine serum albumin nanoparticles as a tumor imaging agent | |
Eshaghi Malekshah et al. | Synthesis and toxicity assessment of Fe3O4 NPs grafted by∼ NH2-Schiff base as anticancer drug: modeling and proposed molecular mechanism through docking and molecular dynamic simulation | |
Sharifi et al. | Fabrication and evaluation of anti-cancer efficacy of lactoferrin-coated maghemite and magnetite nanoparticles | |
Singh et al. | Biosynthesis of folic acid appended PHBV modified copper oxide nanorods for pH sensitive drug release in targeted breast cancer therapy | |
Han et al. | A facile route to form self-carried redox-responsive vorinostat nanodrug for effective solid tumor therapy | |
Li et al. | Iron–gold alloy nanoparticles serve as a cornerstone in hyperthermia-mediated controlled drug release for cancer therapy | |
US9849194B2 (en) | Compositions and methods for imaging and treatment | |
De Castro et al. | Visible light-activated water-soluble platicur nanocolloids: Photocytotoxicity and metabolomics studies in cancer cells | |
ES2796053T3 (en) | Au multicomponent nanomaterials and synthesis methods | |
Chen et al. | Folate conjugated CdHgTe quantum dots with high targeting affinity and sensitivity for in vivo early tumor diagnosis | |
Lu et al. | A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar [5] arene and galactose derivative for targeted drug delivery | |
Mallik et al. | Porous Silica Nanospheres with a Confined Mono (aquated) Mn (II)-Complex: A Potential T 1–T 2 Dual Contrast Agent for Magnetic Resonance Imaging | |
Saha Ray et al. | Set of Highly stable amine-and carboxylate-terminated dendronized Au nanoparticles with dense coating and nontoxic mixed-dendronized form | |
Shi et al. | Fine Regulation of Porous Architectures of Core–Shell Silica Nanocomposites Offers Robust Nanoprobes with Accelerated Responsiveness | |
Shokrollahi et al. | Cytotoxic effect of iron oxide nanoparticles functionalized with glucose and conjugated with Coumarin (Fe3O4@ Glu-Coumarin NPs) on liver cancer, HepG2, cell line |