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Zou et al., 2012 - Google Patents

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Zou et al., 2012

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Document ID
16230769623872296919
Author
Zou F
Chai H
Younkin C
Allen M
Crook J
Pankratz V
Carrasquillo M
Rowley C
Nair A
Middha S
Maharjan S
Nguyen T
Ma L
Malphrus K
Palusak R
Lincoln S
Bisceglio G
Georgescu C
Kouri N
Kolbert C
Jen J
Haines J
Mayeux R
Pericak-Vance M
Farrer L
Schellenberg G
Alzheimer's Disease Genetics Consortium
Petersen R
Graff-Radford N
Dickson D
Younkin S
Ertekin-Taner N
Publication year
Publication venue
PLoS genetics

External Links

Snippet

Genetic variants that modify brain gene expression may also influence risk for human diseases. We measured expression levels of 24,526 transcripts in brain samples from the cerebellum and temporal cortex of autopsied subjects with Alzheimer's disease (AD …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
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