Bush et al., 2000 - Google Patents
Ureidopenicillins and beta-lactam/beta-lactamase inhibitor combinationsBush et al., 2000
- Document ID
- 15696419339730470421
- Author
- Bush L
- Johnson C
- Publication year
- Publication venue
- Infectious disease clinics of North America
External Links
Snippet
The last penicillin to be made available for clinical use in the United States was the combination drug piperacillin-tazobactam. Since approval of this agent by the Food and Drug Administration (FDA) in 1993, research on new penicillins and new indications for …
- 239000003781 beta lactamase inhibitor 0 title abstract description 23
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
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- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
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