Stein et al., 2007 - Google Patents
Opioids: from physical pain to the pain of social isolationStein et al., 2007
- Document ID
- 15142732590098486763
- Author
- Stein D
- van Honk J
- Ipser J
- Solms M
- Panksepp J
- Publication year
- Publication venue
- CNS spectrums
External Links
Snippet
The opioid systems play an important role in mediating both physical pain and negative affects (eg, the pain of social isolation). From an evolutionary perspective, it is not surprising that the neurocircuitry and neurochemistry of physical pain would overlap with that involved …
- 230000003364 opioid 0 title abstract description 38
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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