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Venegas et al., 2012 - Google Patents

Quantification of mtDNA mutation heteroplasmy (ARMS qPCR)

Venegas et al., 2012

Document ID
14599823743324855661
Author
Venegas V
Halberg M
Publication year
Publication venue
Mitochondrial Disorders: Biochemical and Molecular Analysis

External Links

Snippet

Pathogenic mitochondrial DNA (mtDNA) mutations are usually present in heteroplasmic forms that vary in concentration among different tissues. Manifestation of clinical phenotypes depends on the degree of mtDNA mutation heteroplasmy (mutation load) in affected tissues …
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