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Wu et al., 1998 - Google Patents

Characterization of the p125 Subunit of Human DNA Polymerase δ and Its Deletion Mutants: INTERACTION WITH CYCLIN-DEPENDENT KINASE-CYCLINS

Wu et al., 1998

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Document ID
12576657397599997401
Author
Wu S
Zhang P
Zeng X
Zhang S
Mo J
Li B
Lee M
Publication year
Publication venue
Journal of Biological Chemistry

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Snippet

The catalytic subunit of human DNA polymerase (pol) δ was overexpressed in an active, soluble form by the use of a baculovirus system in insect cells. The recombinant enzyme was separated from endogenous DNA polymerases by phosphocellulose, Mono Q …
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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