[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

McCullough et al., 2020 - Google Patents

Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning

McCullough et al., 2020

View HTML @Full View
Document ID
11857359008160776910
Author
McCullough K
Chatzinakos C
Hartmann J
Missig G
Neve R
Fenster R
Carlezon Jr W
Daskalakis N
Ressler K
Publication year
Publication venue
Nature Communications

External Links

Snippet

Fear and extinction learning are adaptive processes caused by molecular changes in specific neural circuits. Neurons expressing the corticotropin-releasing hormone gene (Crh) in central amygdala (CeA) are implicated in threat regulation, yet little is known of cell type …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING; COUNTING
    • G06F—ELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Similar Documents

Publication Publication Date Title
Lorsch et al. Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex
Peña et al. Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
McCullough et al. Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning
Gergues et al. Circuit and molecular architecture of a ventral hippocampal network
Hu et al. Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons
Merienne et al. Cell-type-specific gene expression profiling in adult mouse brain reveals normal and disease-state signatures
Kim et al. Chd2 is necessary for neural circuit development and long-term memory
Barnard et al. Mutations and modeling of the chromatin remodeler CHD8 define an emerging autism etiology
Selvadurai et al. Medulloblastoma arises from the persistence of a rare and transient Sox2+ granule neuron precursor
Petkau et al. Progranulin in neurodegenerative disease
Chen et al. Changes in circular RNA expression patterns during human foetal brain development
Katsel et al. The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription
Rapanelli et al. Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3
Girgenti et al. Transcriptome alterations in posttraumatic stress disorder
McCullough et al. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction
Paden et al. Sex differences in adult mood and in stress-induced transcriptional coherence across mesocorticolimbic circuitry
Zhang et al. Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex
Nätt et al. Perinatal malnutrition leads to sexually dimorphic behavioral responses with associated epigenetic changes in the mouse brain
Scarr et al. Changed frontal pole gene expression suggest altered interplay between neurotransmitter, developmental, and inflammatory pathways in schizophrenia
Baran et al. Ecotype differences in aggression, neural activity and behaviorally relevant gene expression in cichlid fish
Toledo et al. Srebf1 controls midbrain dopaminergic neurogenesis
Duchon et al. Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models
Reuveni et al. Differential contribution of cis and trans gene transcription regulatory mechanisms in amygdala and prefrontal cortex and modulation by social stress
Navandar et al. Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior
Wei et al. Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder