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Fei et al., 2021 - Google Patents

ADAM17 is an essential attachment factor for classical swine fever virus

Fei et al., 2021

Document ID
11705265620858637802
Author
Fei Y
Dandan L
Changyao L
Yanan Z
Hao S
Suhua L
Hongkui D
Gao George F
Aihua Z
et al.
Publication year

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Snippet

Classical swine fever virus (CSFV) is an important pathogen in the swine industry. Virion attachment is mediated by envelope proteins Erns and E2, and E2 is indispensable. Using a pull-down assay with soluble E2 as the bait, we demonstrated that ADAM17, a disintegrin …
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N2310/14Type of nucleic acid interfering N.A.
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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