Want et al., 2005 - Google Patents
The expanding role of mass spectrometry in metabolite profiling and characterizationWant et al., 2005
View PDF- Document ID
- 11013540598790504585
- Author
- Want E
- Cravatt B
- Siuzdak G
- Publication year
- Publication venue
- Chembiochem
External Links
Snippet
Mass spectrometry has a strong history in drug‐metabolite analysis and has recently emerged as the foremost technology in endogenous metabolite research. The advantages of mass spectrometry include a wide dynamic range, the ability to observe a diverse number …
- 238000007884 metabolite profiling 0 title abstract description 30
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Want et al. | The expanding role of mass spectrometry in metabolite profiling and characterization | |
Danzi et al. | To metabolomics and beyond: a technological portfolio to investigate cancer metabolism | |
Nalbantoglu | Metabolomics: basic principles and strategies | |
Want et al. | From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics | |
Roberts et al. | Toward new biomarkers of cardiometabolic diseases | |
Southam et al. | A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics | |
Lu et al. | LC–MS-based metabonomics analysis | |
Scalbert et al. | Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research | |
Gika et al. | Sample preparation prior to the LC–MS-based metabolomics/metabonomics of blood-derived samples | |
Want et al. | Global metabolic profiling procedures for urine using UPLC–MS | |
Barnes et al. | Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data | |
Schlotterbeck et al. | Metabolic profiling technologies for biomarker discovery in biomedicine and drug development | |
Lindon et al. | Metabonomics in pharmaceutical R & D | |
Fiehn | Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks | |
Finehout et al. | An introduction to mass spectrometry applications in biological research | |
Theodoridis et al. | Mass spectrometry‐based holistic analytical approaches for metabolite profiling in systems biology studies | |
Han et al. | Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry | |
Smith et al. | METLIN: a metabolite mass spectral database | |
Barnes et al. | Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its future | |
Pereira et al. | Development and validation of a UPLC/MS method for a nutritional metabolomic study of human plasma | |
Metz et al. | Future of liquid chromatography–mass spectrometry in metabolic profiling and metabolomic studies for biomarker discovery | |
Tebani et al. | Advances in metabolome information retrieval: turning chemistry into biology. Part I: analytical chemistry of the metabolome | |
Lee et al. | Mass spectrometry—based metabolomics, analysis of metabolite-protein interactions, and imaging | |
Han et al. | Mass spectrometry-based technologies for high-throughput metabolomics | |
Song et al. | Technological advances in current metabolomics and its application in tradition Chinese medicine |