Schäfer et al., 2016 - Google Patents
Poly (S-ethylsulfonyl-l-cysteines) for Chemoselective Disulfide FormationSchäfer et al., 2016
- Document ID
- 8790664659352274334
- Author
- Schäfer O
- Huesmann D
- Barz M
- Publication year
- Publication venue
- Macromolecules
External Links
Snippet
The amino acid cysteine possesses a unique role in nature due to its ability to reversibly cross-link proteins. To transfer this feature to polypeptides and control the process of disulfide formation, a protective group needs to provide stability against amines during …
- 230000015572 biosynthetic process 0 title abstract description 115
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48169—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying agent being an organic macromolecular compound, i.e. an oligomeric, polymeric, dendrimeric molecule
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