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Nagaro et al., 1997 - Google Patents

The Effect of Prior Nerve Block on Neuropathic Pain Induced by Partial Sciatic Nerve Injury in Rats

Nagaro et al., 1997

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Document ID
8114600084629095617
Author
Nagaro T
Takaishi K
Kojo H
Disbrow E
Eisele J
Publication year
Publication venue
PAIN RESEARCH

External Links

Snippet

Using the sciatic nerve partial ligation model in rats, we investigated whether prior nerve block have prophylactic effect on the development of neuropathic pain by suppressing initial nerve injury discharge. The sciatic nerve block was done with bupivacaine prior to the …
Continue reading at www.jstage.jst.go.jp (PDF) (other versions)

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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain
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    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
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    • A61K31/47Quinolines; Isoquinolines
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
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