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Zelinski et al., 2009 - Google Patents

A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygen in mice

Zelinski et al., 2009

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Document ID
5446498893313089807
Author
Zelinski L
Ohgami Y
Chung E
Shirachi D
Quock R
Publication year
Publication venue
The journal of pain

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Snippet

Hyperbaric oxygen (HBO2) therapy is reported to cause pain relief in several conditions of chronic pain. A single 60-minute session of HBO2 treatment produced a prolonged antinociceptive effect in mice that persisted for 90 minutes after cessation of treatment. The …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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