Stohr et al., 2001 - Google Patents
Repair of topoisomerase-mediated DNA damage in bacteriophage T4Stohr et al., 2001
View PDF- Document ID
- 4828606776247060487
- Author
- Stohr B
- Kreuzer K
- Publication year
- Publication venue
- Genetics
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Snippet
Type II topoisomerase inhibitors are used to treat both tumors and bacterial infections. These inhibitors stabilize covalent DNA-topoisomerase cleavage complexes that ultimately cause lethal DNA damage. A functional recombinational repair apparatus decreases sensitivity to …
- 101710004466 rgy 0 title abstract description 60
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