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Process losses are pretty common throughout much of the fuel cycle, but Separations is the only archetype with an efficiency, putting the losses in the leftover commod. A few other archetypes would benefit from having a loss stream, especially Mixer, Enrichment. Storage could also have a loss stream, which could be paired with another archetype to model losses in a roundabout way.
For example, 0.2% fuel fabrication losses are a common modeling choice but I don't think that's usually modeled in Cyclus simulations using Cycamore agents because we don't have an easy way to do that