[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Expasy logo

ENZYME

ENZYME entry: EC 2.8.2.33

Accepted Name
N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase
Alternative Name(s)
GalNAc4S-6ST
Reaction catalysed
  • dermatan 4'-sulfate + n 3'-phosphoadenylyl sulfate = dermatan 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)
  • chondroitin 4'-sulfate + n 3'-phosphoadenylyl sulfate = chondroitin 4',6'-bissulfate + n adenosine 3',5'-bisphosphate + n H(+)
Comment(s)
  • The enzyme from human transfers sulfate to position 6 of both internal residues and non-reducing terminal GalNAc 4-sulfate residues of chondroitin sulfate.
  • Oligosaccharides derived from chondroitin sulfate also serve as acceptors but chondroitin sulfate E, keratan sulfate and heparan sulfate do not.
  • Differs from EC 2.8.2.17 in being able to use both chondroitin and dermatan as effective substrates.
Cross-references
BRENDA2.8.2.33
EC2PDB2.8.2.33
ExplorEnz2.8.2.33
PRIAM enzyme-specific profiles2.8.2.33
KEGG Ligand Database for Enzyme Nomenclature2.8.2.33
IUBMB Enzyme Nomenclature2.8.2.33
IntEnz2.8.2.33
MEDLINEFind literature relating to 2.8.2.33
MetaCyc2.8.2.33
Rhea expert-curated reactions2.8.2.33
UniProtKB/Swiss-Prot
Q7LFX5, CHSTF_HUMANQ91XQ5, CHSTF_MOUSEQ8WTN9, CHSTF_NOTSL
Q8CHI9, CHSTF_RAT

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-