ENZYME entry: EC 2.7.8.14

Accepted Name

CDP-ribitol ribitolphosphotransferase

Alternative Name(s)

polyribitol phosphate polymerase

teichoate synthase

teichoic-acid synthase

Reaction catalysed

4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol = 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)

Comment(s)

Involved in the biosynthesis of poly ribitol phosphate teichoic acids in the cell wall of the bacterium Staphylococcus aureus.
This enzyme adds around 40 ribitol units to the linker molecule.
Formerly EC 2.4.1.55.

Cross-references

BRENDA

2.7.8.14

EC2PDB

2.7.8.14

ExplorEnz

2.7.8.14

PRIAM enzyme-specific profiles

2.7.8.14

KEGG Ligand Database for Enzyme Nomenclature

2.7.8.14

IUBMB Enzyme Nomenclature

2.7.8.14

IntEnz

2.7.8.14

MEDLINE

Find literature relating to 2.7.8.14

MetaCyc

2.7.8.14

Rhea expert-curated reactions

2.7.8.14

UniProtKB/Swiss-Prot

Q2G1C2, TARK_STAA8

Q2G1B8, TARL_STAA8

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