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ENZYME

ENZYME entry: EC 2.7.4.21

Accepted Name
inositol-hexakisphosphate 5-kinase
Alternative Name(s)
inositol-hexakisphosphate kinase
IP6K
Reaction catalysed
  • 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP
  • 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP
Comment(s)
  • Three mammalian isoforms are known to exist.
  • Formerly EC 2.7.1.152.
Cross-references
BRENDA2.7.4.21
EC2PDB2.7.4.21
ExplorEnz2.7.4.21
PRIAM enzyme-specific profiles2.7.4.21
KEGG Ligand Database for Enzyme Nomenclature2.7.4.21
IUBMB Enzyme Nomenclature2.7.4.21
IntEnz2.7.4.21
MEDLINEFind literature relating to 2.7.4.21
MetaCyc2.7.4.21
Rhea expert-curated reactions2.7.4.21
UniProtKB/Swiss-Prot
Q92551, IP6K1_HUMANQ6PD10, IP6K1_MOUSEQ9ESM0, IP6K1_RAT
Q96PC2, IP6K3_HUMANQ8BWD2, IP6K3_MOUSEQ84Y01, ITPK1_MAIZE
A7X657, ITPK1_SOYBNA7X665, ITPK2_SOYBNQ12494, KCS1_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-