ENZYME entry: EC 2.7.11.3

Accepted Name
dephospho-[reductase kinase] kinase
Alternative Name(s)
AMP-activated kinase
AMP-activated protein kinase kinase
hydroxymethylglutaryl coenzyme A reductase kinase kinase
reductase kinase
reductase kinase kinase
Reaction catalysed
ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]
Comment(s)
Activated by AMP and is specific for its substrate. Phosphorylates and activates EC 2.7.11.31 which has been inactivated by EC 3.1.3.16. Formerly EC 2.7.1.110.
Cross-references
BRENDA	2.7.11.3
EC2PDB	2.7.11.3
ExplorEnz	2.7.11.3
PRIAM enzyme-specific profiles	2.7.11.3
KEGG Ligand Database for Enzyme Nomenclature	2.7.11.3
IUBMB Enzyme Nomenclature	2.7.11.3
IntEnz	2.7.11.3
MEDLINE	Find literature relating to 2.7.11.3
MetaCyc	2.7.11.3
Rhea expert-curated reactions	2.7.11.3

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-