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ENZYME

ENZYME entry: EC 2.5.1.10

Accepted Name
(2E,6E)-farnesyl diphosphate synthase
Alternative Name(s)
farnesyl-diphosphate synthase
farnesyl pyrophosphate synthetase
FPP synthetase
geranyltranstransferase
Reaction catalysed
isopentenyl diphosphate + (2E)-geranyl diphosphate = (2E,6E)-farnesyl diphosphate + diphosphate
Comment(s)
  • Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
  • The enzyme will not accept larger prenyl diphosphates as efficient donors.
Cross-references
BRENDA2.5.1.10
EC2PDB2.5.1.10
ExplorEnz2.5.1.10
PRIAM enzyme-specific profiles2.5.1.10
KEGG Ligand Database for Enzyme Nomenclature2.5.1.10
IUBMB Enzyme Nomenclature2.5.1.10
IntEnz2.5.1.10
MEDLINEFind literature relating to 2.5.1.10
MetaCyc2.5.1.10
Rhea expert-curated reactions2.5.1.10
UniProtKB/Swiss-Prot
Q672V6, ATMG_ASPFLA0A3S5XFG0, CLE6_ASPVEB1XJV9, CRTE_PICP2
P9WEX3, DPASD_APISAH1VQB1, DPCHD_COLHII1RL14, DPFGD_GIBZE
P9WEX9, DPMAD_METANP9WEW8, DPMPD_MACPHQ4WEB8, ERG20_ASPFU
A0A1D8PH78, ERG20_CANALB4YA15, ERG20_GANLUV6RG22, ERG20_GIBZE
O14230, ERG20_SCHPOP08524, ERG20_YEASTA0A1V0QSA8, ERIE_HERER
A0A8D5M3Y5, ESDPD_PENSHQ09152, FPPS1_ARATHQ7XYS9, FPPS1_ARTSI
A0A7J6HWR9, FPPS1_CANSAP49351, FPPS1_LUPALO24241, FPPS1_PARAR
Q43315, FPPS2_ARATHQ7XYT0, FPPS2_ARTSIA0A1V0QSH7, FPPS2_CANSA
P49352, FPPS2_LUPALO24242, FPPS2_PARARP49350, FPPS_ARTAN
Q8WMY2, FPPS_BOVINP08836, FPPS_CHICKQ92235, FPPS_GIBFU
O64905, FPPS_HELANP14324, FPPS_HUMANP49349, FPPS_KLULA
P49353, FPPS_MAIZEQ920E5, FPPS_MOUSEA0A343W970, FPPS_MURHI
P0A5H9, FPPS_MYCBOP9WKH0, FPPS_MYCTOP9WKH1, FPPS_MYCTU
Q92250, FPPS_NEUCRP05369, FPPS_RATQ9NH03, FPS_DICDI
Q4JHN6, FPS_PANGIS0E627, GA5_GIBF5O53507, GFPPS_MYCTU
A0A858E6N7, GGDPS_MELLIA0A858E7G0, GGDPS_MELLPP34802, GGPP1_ARATH
O04046, GGPP2_ARATHQ9LUD9, GGPP3_ARATHQ9SLG2, GGPP4_ARATH
O22043, GGPP6_ARATHQ9ZU77, GGPP7_ARATHQ9LRR0, GGPP8_ARATH
Q9LUE1, GGPP9_ARATHQ9LJY2, GGPPA_ARATHQ9LIA0, GGPPB_ARATH
Q9LHR4, GGPPC_ARATHP56966, GGPPS_BOVINP80042, GGPPS_CAPAN
Q42698, GGPPS_CATROQ54BK1, GGPPS_DICDIQ758K0, GGPPS_EREGS
A0A0A7GEY4, GGPPS_GEOAIQ92236, GGPPS_GIBFUQ94ID7, GGPPS_HEVBR
O95749, GGPPS_HUMANQ9WTN0, GGPPS_MOUSEQ9P885, GGPPS_MUCCL
P24322, GGPPS_NEUCRQ6F596, GGPPS_RATO59703, GGPPS_SCHPO
Q43133, GGPPS_SINALQ12051, GGPPS_YEASTA0A2I6PJ05, GGS1_HYPPI
B2DBE8, GGS1_PHOAMF9WWF1, GGS2_ZYMTIF9XLC1, GGS3_ZYMTI
B2DBE9, GGS4_PHOAMQ6F5E6, GGS_NEOBTF9WZD2, GSS1_ZYMTI
J7FIX8, IDTG_CLAPAO66952, ISPA_AQUAEP54383, ISPA_BACSU
Q45220, ISPA_BRADUP57537, ISPA_BUCAIQ8K9A0, ISPA_BUCAP
P22939, ISPA_ECOLIQ08291, ISPA_GEOSEP45204, ISPA_HAEIN
O66126, ISPA_MICLUP55539, ISPA_SINFNA0A0E3D8M9, JANG_PENJA
Q56RZ3, LTMG_EPIFFQ56RZ7, LTMG_EPIFIO06428, NPPPS_MYCTU
P9WEQ2, OLCC_PENCNQ9C446, PAXG_PENPXA0A1U8QLG8, PBCB_EMENI
A0A0E3D8P4, PENG_PENCRA0A2L0VXR5, PLE4_CLIPAA0A6S6QJ62, PLE4_RHOPP
A0A140JWS2, PTMG_PENSIA0A1B4XBK0, SDNC_SORAAQ4WBI4, SPYE_ASPFU
E9F5E9, SUBD_METRAQ65164, TPRT_ASFB7P0C9E2, TPRT_ASFK5
Q8V9T7, TPRT_ASFM2P0C9E0, TPRT_ASFP4P0C9E1, TPRT_ASFWA
D7PHZ5, VRTD_PENAEQ55EU7, Y8742_DICDIQ54XP1, Y8823_DICDI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-