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ENZYME

ENZYME entry: EC 2.5.1.94

Accepted Name
adenosyl-chloride synthase
Alternative Name(s)
5'-chloro-5'-deoxyadenosine synthase
chlorinase
Reaction catalysed
chloride + S-adenosyl-L-methionine = 5'-chloro-5'-deoxyadenosine + L-methionine
Comment(s)
  • This enzyme, isolated from the marine bacterium Salinispora tropica, catalyzes an early step in the pathway leading to biosynthesis of the proteosome inhibitor salinosporamide A.
  • The enzyme is very similar to EC 2.5.1.63 but does not accept fluoride.
Cross-references
BRENDA2.5.1.94
EC2PDB2.5.1.94
ExplorEnz2.5.1.94
PRIAM enzyme-specific profiles2.5.1.94
KEGG Ligand Database for Enzyme Nomenclature2.5.1.94
IUBMB Enzyme Nomenclature2.5.1.94
IntEnz2.5.1.94
MEDLINEFind literature relating to 2.5.1.94
MetaCyc2.5.1.94
Rhea expert-curated reactions2.5.1.94
UniProtKB/Swiss-Prot
W8JNL4, FLA_NOCB7W0W999, FLA_STRSQA4X3Q0, SALL_SALTO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-