ENZYME entry: EC 2.4.1.135
| Accepted Name | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase | |||||||||||||||||
| Alternative Name(s) | |||||||||||||||||
| glucuronosyltransferase I | |||||||||||||||||
| uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase | |||||||||||||||||
| Reaction catalysed | |||||||||||||||||
| 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+) | |||||||||||||||||
| Comment(s) | |||||||||||||||||
| Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates). | |||||||||||||||||
| Cross-references | |||||||||||||||||
| BRENDA | 2.4.1.135 | ||||||||||||||||
| EC2PDB | 2.4.1.135 | ||||||||||||||||
| ExplorEnz | 2.4.1.135 | ||||||||||||||||
| PRIAM enzyme-specific profiles | 2.4.1.135 | ||||||||||||||||
| KEGG Ligand Database for Enzyme Nomenclature | 2.4.1.135 | ||||||||||||||||
| IUBMB Enzyme Nomenclature | 2.4.1.135 | ||||||||||||||||
| IntEnz | 2.4.1.135 | ||||||||||||||||
| MEDLINE | Find literature relating to 2.4.1.135 | ||||||||||||||||
| MetaCyc | 2.4.1.135 | ||||||||||||||||
| Rhea expert-curated reactions | 2.4.1.135 | ||||||||||||||||
| UniProtKB/Swiss-Prot |
| ||||||||||||||||
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