[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Expasy logo

ENZYME

ENZYME entry: EC 2.1.1.282

Accepted Name
tRNA(Phe) 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4)]- methyltransferase
Alternative Name(s)
tRNA-yW synthesizing enzyme-3
Reaction catalysed
4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • The enzyme is involved in the biosynthesis of hypermodified tricyclic bases found at position 37 of certain tRNAs.
  • These modifications are important for translational reading-frame maintenance.
  • The enzyme is found in all eukaryotes and in some archaea, but not in bacteria.
  • The eukaryotic enzyme is involved in the biosynthesis of wybutosine.
Cross-references
BRENDA2.1.1.282
EC2PDB2.1.1.282
ExplorEnz2.1.1.282
PRIAM enzyme-specific profiles2.1.1.282
KEGG Ligand Database for Enzyme Nomenclature2.1.1.282
IUBMB Enzyme Nomenclature2.1.1.282
IntEnz2.1.1.282
MEDLINEFind literature relating to 2.1.1.282
MetaCyc2.1.1.282
Rhea expert-curated reactions2.1.1.282
UniProtKB/Swiss-Prot
Q8W4K1, TYW23_ARATHQ8H4D4, TYW23_ORYSJQ9V074, TYW31_PYRAB
Q8U1V7, TYW31_PYRFUO58796, TYW31_PYRHOQ5JFK6, TYW31_THEKO
Q9V1Y5, TYW32_PYRABQ8TZG0, TYW32_PYRFUO59533, TYW32_PYRHO
Q5JES6, TYW32_THEKOQ9YDV3, TYW3_AERPEO28220, TYW3_ARCFU
Q5E9U4, TYW3_BOVINQ6DHJ1, TYW3_DANREQ6IPR3, TYW3_HUMAN
Q58905, TYW3_METJAQ8BSA9, TYW3_MOUSEQ19QT9, TYW3_PIG
Q5R5S9, TYW3_PONABQ9UX16, TYW3_SACS2Q9UTA5, TYW3_SCHPO
C6A5A3, TYW3_THESMQ641F8, TYW3_XENLAP53177, TYW3_YEAST

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-