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ENZYME

ENZYME entry: EC 2.1.1.174

Accepted Name
23S rRNA (guanine(1835)-N(2))-methyltransferase
Alternative Name(s)
ribosomal RNA large subunit methyltransferase G
Reaction catalysed
guanosine(1835) in 23S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.
  • The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA.
  • Formerly EC 2.1.1.52.
Cross-references
BRENDA2.1.1.174
EC2PDB2.1.1.174
ExplorEnz2.1.1.174
PRIAM enzyme-specific profiles2.1.1.174
KEGG Ligand Database for Enzyme Nomenclature2.1.1.174
IUBMB Enzyme Nomenclature2.1.1.174
IntEnz2.1.1.174
MEDLINEFind literature relating to 2.1.1.174
MetaCyc2.1.1.174
Rhea expert-curated reactions2.1.1.174
UniProtKB/Swiss-Prot
A0KHC4, RLMG_AERHHA4SQM2, RLMG_AERS4Q0VPK2, RLMG_ALCBS
Q5E6X8, RLMG_ALIF1B5FBH8, RLMG_ALIFMB6EIC1, RLMG_ALISL
B4RZB4, RLMG_ALTMDA8APY0, RLMG_CITK8Q488Q3, RLMG_COLP3
A7MIS8, RLMG_CROS8A7ZRW7, RLMG_ECO24Q8XAK8, RLMG_ECO57
B5YRC4, RLMG_ECO5EB1XG88, RLMG_ECODHA8A4P1, RLMG_ECOHS
A1AG02, RLMG_ECOK1Q0TD22, RLMG_ECOL5Q8FDE5, RLMG_ECOL6
B1IRN3, RLMG_ECOLCP42596, RLMG_ECOLIB1LFI2, RLMG_ECOSM
Q1R6P6, RLMG_ECOUTA4WER8, RLMG_ENT38B2VDD5, RLMG_ERWT9
B5XTX7, RLMG_KLEP3A6TEC2, RLMG_KLEP7A0L9S5, RLMG_MAGMM
Q6D9G1, RLMG_PECASQ6LTZ3, RLMG_PHOPRQ48DT7, RLMG_PSE14
Q15YR1, RLMG_PSEA6A6VC08, RLMG_PSEA7Q02G60, RLMG_PSEAB
Q9HVH4, RLMG_PSEAEQ1I4K4, RLMG_PSEE4Q4K5Q4, RLMG_PSEF5
A4XQA3, RLMG_PSEMYA5W920, RLMG_PSEP1Q3K6H7, RLMG_PSEPF
B0KHQ8, RLMG_PSEPGQ88E20, RLMG_PSEPKB1J2W7, RLMG_PSEPW
Q0EDR2, RLMG_PSESHQ87WA9, RLMG_PSESMQ3IHQ6, RLMG_PSET1
Q4ZNG3, RLMG_PSEU2A1SX22, RLMG_PSYINB5F6B6, RLMG_SALA4
A9MPU2, RLMG_SALARQ57JN9, RLMG_SALCHB5FHV5, RLMG_SALDC
B5QZ55, RLMG_SALEPB5REH7, RLMG_SALG2B4TIU8, RLMG_SALHS
B4T690, RLMG_SALNSQ5PC93, RLMG_SALPAA9N601, RLMG_SALPB
B5BG31, RLMG_SALPKB4TVV4, RLMG_SALSVQ8Z3L8, RLMG_SALTI
Q8ZLX5, RLMG_SALTYA8GJW6, RLMG_SERP5A1S8P4, RLMG_SHEAM
A3D130, RLMG_SHEB5A6WRY2, RLMG_SHEB8A9L0V0, RLMG_SHEB9
Q12K11, RLMG_SHEDOQ07YH6, RLMG_SHEFNB0TR07, RLMG_SHEHH
A3QH04, RLMG_SHELPQ8EHW5, RLMG_SHEONA8H786, RLMG_SHEPA
A4Y3Y0, RLMG_SHEPCA0KTP8, RLMG_SHESAA8FYW7, RLMG_SHESH
Q0HLQ7, RLMG_SHESMQ0HY38, RLMG_SHESRA1RN12, RLMG_SHESW
B1KD54, RLMG_SHEWMB2U1T3, RLMG_SHIB3Q31WU9, RLMG_SHIBS
Q32BN8, RLMG_SHIDSQ0T0I4, RLMG_SHIF8Q821A5, RLMG_SHIFL
Q3YXQ6, RLMG_SHISSQ82N59, RLMG_STRAWQ9K3L9, RLMG_STRCO
B1VMX8, RLMG_STRGGA4VI28, RLMG_STUS1B7VKD0, RLMG_VIBA3
A7N1U8, RLMG_VIBC1A5F5X3, RLMG_VIBC3Q9KPR9, RLMG_VIBCH
Q87MA4, RLMG_VIBPAQ8DBJ8, RLMG_VIBVUQ7MIC5, RLMG_VIBVY
A1JR10, RLMG_YERE8A7FE15, RLMG_YERP3Q1C310, RLMG_YERPA
B2K3B8, RLMG_YERPBQ0WJ78, RLMG_YERPEA9R1N3, RLMG_YERPG
Q1CMJ1, RLMG_YERPNA4THM8, RLMG_YERPPQ665P6, RLMG_YERPS
B1JLA4, RLMG_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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